ATE360029T1 - Verfahren zur herstellung von glycopeptidderivaten - Google Patents

Verfahren zur herstellung von glycopeptidderivaten

Info

Publication number
ATE360029T1
ATE360029T1 AT02759433T AT02759433T ATE360029T1 AT E360029 T1 ATE360029 T1 AT E360029T1 AT 02759433 T AT02759433 T AT 02759433T AT 02759433 T AT02759433 T AT 02759433T AT E360029 T1 ATE360029 T1 AT E360029T1
Authority
AT
Austria
Prior art keywords
glycopeptide derivatives
producing glycopeptide
producing
derivatives
isolation
Prior art date
Application number
AT02759433T
Other languages
English (en)
Inventor
Junning Lee
Jyanwei Liu
Original Assignee
Theravance Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Theravance Inc filed Critical Theravance Inc
Application granted granted Critical
Publication of ATE360029T1 publication Critical patent/ATE360029T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/006—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure
    • C07K9/008—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure directly attached to a hetero atom of the saccharide radical, e.g. actaplanin, avoparcin, ristomycin, vancomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT02759433T 2001-08-24 2002-08-23 Verfahren zur herstellung von glycopeptidderivaten ATE360029T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US31471101P 2001-08-24 2001-08-24

Publications (1)

Publication Number Publication Date
ATE360029T1 true ATE360029T1 (de) 2007-05-15

Family

ID=23221113

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02759433T ATE360029T1 (de) 2001-08-24 2002-08-23 Verfahren zur herstellung von glycopeptidderivaten

Country Status (14)

Country Link
US (2) US7015305B2 (de)
EP (1) EP1419174B1 (de)
JP (1) JP4116546B2 (de)
KR (1) KR100909435B1 (de)
CN (1) CN1281619C (de)
AT (1) ATE360029T1 (de)
AU (1) AU2002324768A1 (de)
CA (1) CA2457215C (de)
DE (1) DE60219638T2 (de)
DK (1) DK1419174T3 (de)
ES (1) ES2284907T3 (de)
NO (1) NO335304B1 (de)
TW (1) TWI312785B (de)
WO (1) WO2003018607A2 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6951963B2 (en) 2002-06-17 2005-10-04 Theravance, Inc. Process for preparing N-protected β-amino aldehyde compounds
TWI342312B (en) * 2003-10-22 2011-05-21 Theravance Inc Hydrochloride salts of a glycopeptide phosphonate derivative
WO2006024741A2 (fr) * 2004-07-30 2006-03-09 Palumed S.A. Molecules hybrides qa ou q est une aminoquinoleine et a est un residu antibiotique, leur synthese et leurs utilisations en tant qu'agent antibacterien
EP2753638A1 (de) 2011-09-09 2014-07-16 Sandoz AG Verfahren zur synthese von telavancin und seinen pharmazeutisch akzeptablen salzen sowie n-geschützte derivate daraus
EP2753637A1 (de) 2011-09-09 2014-07-16 Sandoz AG Verfahren zur synthese von telavancin, seine pharmazeutisch akzeptablen salze sowie ein n-geschütztes iminderivat von telavancin
US20160243190A1 (en) 2015-02-23 2016-08-25 Theravance Biopharma Antibiotics Ip, Llc Doses and methods for administering telavancin
CN106467570B (zh) * 2015-08-14 2020-04-07 正大天晴药业集团股份有限公司 糖肽类抗生素的还原烷基化方法
CN106631902A (zh) * 2016-09-23 2017-05-10 上海步越化工科技有限公司 一种特拉万星侧链癸基(2‑氧代乙基)氨基甲酸9h‑芴‑9‑甲基酯的制备方法
GB2577419B (en) 2017-05-22 2022-08-17 Insmed Inc Lipo-glycopeptide cleavable derivatives and uses thereof
CN111233713A (zh) * 2020-01-20 2020-06-05 福建康鸿生物科技有限公司 一种特拉万星中间体合成方法
WO2022198009A1 (en) * 2021-03-18 2022-09-22 Insmed Incorporated Dry powder compositions of glycopeptide derivative compounds and methods of use thereof

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3160632A (en) * 1961-01-30 1964-12-08 Stauffer Chemical Co Aminomethylenephosphinic acids, salts thereof, and process for their production
IL78597A0 (en) 1985-04-25 1986-08-31 Lilly Co Eli Novel glycopeptide derivatives
US4698327A (en) * 1985-04-25 1987-10-06 Eli Lilly And Company Novel glycopeptide derivatives
US4643987A (en) * 1985-08-14 1987-02-17 Eli Lilly And Company Modified glycopeptides
EP0273727A3 (de) 1986-12-30 1990-01-17 Smithkline Beecham Corporation Glykosilierte Glycopeptide
EP0376041B1 (de) * 1988-12-27 1996-02-28 GRUPPO LEPETIT S.p.A. C63-Amidderivate von 34-de(acetylglucosaminyl)-34-deoxy-teicoplaninen
NZ236393A (en) * 1989-12-13 1992-05-26 Lilly Co Eli N-alkylated glycopeptide derivatives prepared from antibiotics a82846 series and pa-42867-a; pharmaceutical compositions
US5750509A (en) * 1991-07-29 1998-05-12 Gruppo Lepetit S.P.A. Amide derivatives of antibiotic A 40926
HU223946B1 (hu) * 1991-07-29 2005-03-29 Vicuron Pharmaceuticals Inc. Eljárás az A 40926 glikopeptid antibiotikum-származékai és az azokat hatóanyagként tartalmazó gyógyszerkészítmények előállítására
US5840684A (en) * 1994-01-28 1998-11-24 Eli Lilly And Company Glycopeptide antibiotic derivatives
MY128335A (en) 1994-01-28 2007-01-31 Lilly Co Eli Glycopeptide antibiotic derivatives
US5918873A (en) * 1995-03-30 1999-07-06 Canon Kabushiki Kaisha Sheet supplying apparatus which regulates tip end of sheet by first and second abutment means
US5919756A (en) 1996-06-28 1999-07-06 Eli Lilly And Company Amides
US5939382A (en) 1996-11-21 1999-08-17 Eli Lilly And Company Reducing agent for reductive alkylation of glycopeptide antibiotics
US5952466A (en) * 1997-11-12 1999-09-14 Eli Lilly And Company Reductive alkylation of glycopeptide antibiotics
US5916873A (en) 1997-04-17 1999-06-29 Eli Lilly And Company Teicoplanin derivatives
AU3307399A (en) 1998-02-20 1999-09-06 Advanced Medicine, Inc. Novel antibacterial agents
US6518242B1 (en) * 1998-02-20 2003-02-11 Theravance, Inc. Derivatives of glycopeptide antibacterial agents
PT1140993E (pt) * 1998-12-23 2003-10-31 Theravance Inc Derivados de glicopeptidos e composicoes farmaceuticas contendo os mesmos
CA2370782A1 (en) 1999-04-02 2000-10-12 The Trustees Of Princeton University Desleucyl glycopeptide antibiotics and methods of making same
AU2001238020A1 (en) * 2000-02-04 2001-08-14 Advanced Medicine, Inc. Glycopeptide derivatives having antibiotic activity
CN1223378C (zh) * 2000-05-02 2005-10-19 施万制药 含有糖肽抗生素和环糊精的药物组合物
ATE402951T1 (de) 2000-05-02 2008-08-15 Theravance Inc Verfahren zur reduktiven alkylierung von glykopeptiden
UA75083C2 (uk) * 2000-06-22 2006-03-15 Тераванс, Інк. Похідні глікопептидфосфонатів

Also Published As

Publication number Publication date
NO20040779L (no) 2004-02-23
JP2005525997A (ja) 2005-09-02
TWI312785B (en) 2009-08-01
CA2457215C (en) 2011-12-13
US20030045457A1 (en) 2003-03-06
EP1419174A4 (de) 2005-10-12
KR100909435B1 (ko) 2009-07-28
DK1419174T3 (da) 2007-07-02
CN1610692A (zh) 2005-04-27
DE60219638D1 (de) 2007-05-31
NO335304B1 (no) 2014-11-10
AU2002324768A1 (en) 2003-03-10
US20060058503A1 (en) 2006-03-16
US7160984B2 (en) 2007-01-09
EP1419174B1 (de) 2007-04-18
ES2284907T3 (es) 2007-11-16
DE60219638T2 (de) 2007-12-20
KR20040028997A (ko) 2004-04-03
US7015305B2 (en) 2006-03-21
EP1419174A2 (de) 2004-05-19
JP4116546B2 (ja) 2008-07-09
WO2003018607A2 (en) 2003-03-06
CA2457215A1 (en) 2003-03-06
WO2003018607A3 (en) 2003-11-27
CN1281619C (zh) 2006-10-25

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties