ATE356221T1 - Sequenzierung durch ligation kodierter adapter - Google Patents
Sequenzierung durch ligation kodierter adapterInfo
- Publication number
- ATE356221T1 ATE356221T1 AT97929757T AT97929757T ATE356221T1 AT E356221 T1 ATE356221 T1 AT E356221T1 AT 97929757 T AT97929757 T AT 97929757T AT 97929757 T AT97929757 T AT 97929757T AT E356221 T1 ATE356221 T1 AT E356221T1
- Authority
- AT
- Austria
- Prior art keywords
- encoded
- ligation
- protruding strands
- ligated
- target polynucleotide
- Prior art date
Links
- 238000007841 sequencing by ligation Methods 0.000 title 1
- 230000000295 complement effect Effects 0.000 abstract 2
- 108091033319 polynucleotide Proteins 0.000 abstract 2
- 102000040430 polynucleotide Human genes 0.000 abstract 2
- 239000002157 polynucleotide Substances 0.000 abstract 2
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 1
- 108091034117 Oligonucleotide Proteins 0.000 abstract 1
- 238000012300 Sequence Analysis Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 150000007523 nucleic acids Chemical group 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates
- C12Q1/6855—Ligating adaptors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
- C12Q1/6874—Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Saccharide Compounds (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/659,453 US5846719A (en) | 1994-10-13 | 1996-06-06 | Oligonucleotide tags for sorting and identification |
| US68958796A | 1996-08-12 | 1996-08-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE356221T1 true ATE356221T1 (de) | 2007-03-15 |
Family
ID=27097828
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97929757T ATE356221T1 (de) | 1996-06-06 | 1997-06-02 | Sequenzierung durch ligation kodierter adapter |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP0923650B1 (enExample) |
| JP (1) | JP4124377B2 (enExample) |
| CN (1) | CN1195872C (enExample) |
| AT (1) | ATE356221T1 (enExample) |
| AU (1) | AU733782B2 (enExample) |
| CA (1) | CA2256700A1 (enExample) |
| CZ (1) | CZ397998A3 (enExample) |
| DE (1) | DE69737450T2 (enExample) |
| HU (1) | HUP0003944A3 (enExample) |
| NO (1) | NO985698L (enExample) |
| PL (1) | PL331513A1 (enExample) |
| WO (1) | WO1997046704A1 (enExample) |
Families Citing this family (90)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| USRE43097E1 (en) | 1994-10-13 | 2012-01-10 | Illumina, Inc. | Massively parallel signature sequencing by ligation of encoded adaptors |
| ATE466109T1 (de) * | 1995-06-07 | 2010-05-15 | Solexa Inc | Verfahren zur verbesserung der effizienz der polynukleotidsequenzierung |
| GB9620769D0 (en) * | 1996-10-04 | 1996-11-20 | Brax Genomics Ltd | Nucleic acid sequencing |
| US5888737A (en) * | 1997-04-15 | 1999-03-30 | Lynx Therapeutics, Inc. | Adaptor-based sequence analysis |
| JP4294740B2 (ja) | 1997-05-23 | 2009-07-15 | ソレクサ・インコーポレイテッド | 分析物の系列的プロセシングのためのシステムおよび装置 |
| US6607878B2 (en) | 1997-10-06 | 2003-08-19 | Stratagene | Collections of uniquely tagged molecules |
| US6265163B1 (en) | 1998-01-09 | 2001-07-24 | Lynx Therapeutics, Inc. | Solid phase selection of differentially expressed genes |
| JP3944996B2 (ja) | 1998-03-05 | 2007-07-18 | 株式会社日立製作所 | Dnaプローブアレー |
| AU754952B2 (en) | 1998-06-24 | 2002-11-28 | Illumina, Inc. | Decoding of array sensors with microspheres |
| US6480791B1 (en) * | 1998-10-28 | 2002-11-12 | Michael P. Strathmann | Parallel methods for genomic analysis |
| NO986133D0 (no) * | 1998-12-23 | 1998-12-23 | Preben Lexow | FremgangsmÕte for DNA-sekvensering |
| WO2000039333A1 (en) * | 1998-12-23 | 2000-07-06 | Jones Elizabeth Louise | Sequencing method using magnifying tags |
| AU778438B2 (en) * | 1999-04-06 | 2004-12-02 | Yale University | Fixed address analysis of sequence tags |
| US20060275782A1 (en) | 1999-04-20 | 2006-12-07 | Illumina, Inc. | Detection of nucleic acid reactions on bead arrays |
| WO2000075373A2 (en) * | 1999-05-20 | 2000-12-14 | Illumina, Inc. | Combinatorial decoding of random nucleic acid arrays |
| US6544732B1 (en) | 1999-05-20 | 2003-04-08 | Illumina, Inc. | Encoding and decoding of array sensors utilizing nanocrystals |
| US8080380B2 (en) | 1999-05-21 | 2011-12-20 | Illumina, Inc. | Use of microfluidic systems in the detection of target analytes using microsphere arrays |
| US8481268B2 (en) | 1999-05-21 | 2013-07-09 | Illumina, Inc. | Use of microfluidic systems in the detection of target analytes using microsphere arrays |
| EP1206577B1 (en) * | 1999-08-13 | 2006-03-01 | Yale University | Binary encoded sequence tags |
| EP1218545B1 (en) | 1999-08-18 | 2012-01-25 | Illumina, Inc. | Methods for preparing oligonucleotide solutions |
| AU3806701A (en) | 2000-02-07 | 2001-08-14 | Illumina Inc | Nucleic acid detection methods using universal priming |
| US7582420B2 (en) | 2001-07-12 | 2009-09-01 | Illumina, Inc. | Multiplex nucleic acid reactions |
| DE60136166D1 (de) | 2000-02-07 | 2008-11-27 | Illumina Inc | Nukleinsäure-nachweisverfahren mit universellem priming |
| US7611869B2 (en) | 2000-02-07 | 2009-11-03 | Illumina, Inc. | Multiplexed methylation detection methods |
| US7361488B2 (en) | 2000-02-07 | 2008-04-22 | Illumina, Inc. | Nucleic acid detection methods using universal priming |
| DE60136335D1 (de) | 2000-02-16 | 2008-12-11 | Illumina Inc | Parallele genotypisierung mehrerer patientenproben |
| WO2003102216A2 (en) * | 2002-05-31 | 2003-12-11 | Diversa Corporation | Multiplexed systems for nucleic acid sequencing |
| CA2513985C (en) | 2003-01-21 | 2012-05-29 | Illumina Inc. | Chemical reaction monitor |
| EP1594980B2 (en) * | 2003-01-29 | 2017-08-16 | 454 Life Sciences Corporation | Bead emulsion nucleic acid amplification |
| GB0308852D0 (en) * | 2003-04-16 | 2003-05-21 | Lingvitae As | Method |
| WO2005010184A1 (ja) * | 2003-07-25 | 2005-02-03 | Takara Bio Inc. | 変異の検出方法 |
| GB0324456D0 (en) | 2003-10-20 | 2003-11-19 | Isis Innovation | Parallel DNA sequencing methods |
| US7622281B2 (en) | 2004-05-20 | 2009-11-24 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and compositions for clonal amplification of nucleic acid |
| US20080003571A1 (en) | 2005-02-01 | 2008-01-03 | Mckernan Kevin | Reagents, methods, and libraries for bead-based sequencing |
| GB0524069D0 (en) | 2005-11-25 | 2006-01-04 | Solexa Ltd | Preparation of templates for solid phase amplification |
| SG169356A1 (en) * | 2006-02-08 | 2011-03-30 | Illumina Cambridge Ltd | Method for sequencing a polynucleotide template |
| WO2007097443A1 (ja) * | 2006-02-20 | 2007-08-30 | National University Corporation Hokkaido University | Dna塩基配列を決定する方法 |
| CN101495654A (zh) * | 2006-04-19 | 2009-07-29 | 阿普里拉股份有限公司 | 无凝胶珠基测序的试剂、方法和文库 |
| CN101495656B (zh) | 2006-06-07 | 2017-02-08 | 纽约哥伦比亚大学理事会 | 采用带修饰的核苷酸通过纳米通道进行dna序列测定 |
| US9678055B2 (en) | 2010-02-08 | 2017-06-13 | Genia Technologies, Inc. | Methods for forming a nanopore in a lipid bilayer |
| US9605307B2 (en) | 2010-02-08 | 2017-03-28 | Genia Technologies, Inc. | Systems and methods for forming a nanopore in a lipid bilayer |
| US8324914B2 (en) | 2010-02-08 | 2012-12-04 | Genia Technologies, Inc. | Systems and methods for characterizing a molecule |
| US9121059B2 (en) | 2010-12-22 | 2015-09-01 | Genia Technologies, Inc. | Nanopore-based single molecule characterization |
| US9581563B2 (en) | 2011-01-24 | 2017-02-28 | Genia Technologies, Inc. | System for communicating information from an array of sensors |
| US9110478B2 (en) | 2011-01-27 | 2015-08-18 | Genia Technologies, Inc. | Temperature regulation of measurement arrays |
| SG194745A1 (en) * | 2011-05-20 | 2013-12-30 | Fluidigm Corp | Nucleic acid encoding reactions |
| US10501791B2 (en) | 2011-10-14 | 2019-12-10 | President And Fellows Of Harvard College | Sequencing by structure assembly |
| ES2991004T3 (es) | 2011-12-22 | 2024-12-02 | Harvard College | Métodos para la detección de analitos |
| ES2953308T3 (es) | 2011-12-22 | 2023-11-10 | Harvard College | Composiciones y métodos para la detección de analitos |
| WO2014163886A1 (en) | 2013-03-12 | 2014-10-09 | President And Fellows Of Harvard College | Method of generating a three-dimensional nucleic acid containing matrix |
| US8986629B2 (en) | 2012-02-27 | 2015-03-24 | Genia Technologies, Inc. | Sensor circuit for controlling, detecting, and measuring a molecular complex |
| CN102766689B (zh) * | 2012-04-17 | 2015-07-22 | 盛司潼 | 一种增加测序读长的测序方法 |
| AU2013251701A1 (en) * | 2012-04-24 | 2014-10-30 | Gen9, Inc. | Methods for sorting nucleic acids and multiplexed preparative in vitro cloning |
| ES2905448T3 (es) * | 2012-05-10 | 2022-04-08 | Massachusetts Gen Hospital | Métodos para determinar una secuencia nucleotídica |
| US9914967B2 (en) | 2012-06-05 | 2018-03-13 | President And Fellows Of Harvard College | Spatial sequencing of nucleic acids using DNA origami probes |
| GB2510719A (en) | 2012-06-15 | 2014-08-13 | Genia Technologies Inc | Chip set-up and high-accuracy nucleic acid sequencing |
| US9605309B2 (en) | 2012-11-09 | 2017-03-28 | Genia Technologies, Inc. | Nucleic acid sequencing using tags |
| US9759711B2 (en) | 2013-02-05 | 2017-09-12 | Genia Technologies, Inc. | Nanopore arrays |
| US10648026B2 (en) | 2013-03-15 | 2020-05-12 | The Trustees Of Columbia University In The City Of New York | Raman cluster tagged molecules for biological imaging |
| MY177814A (en) | 2013-06-04 | 2020-09-23 | Harvard College | Rna-guided transcriptional regulation |
| EP3052645B1 (en) * | 2013-09-30 | 2019-01-09 | Qiagen GmbH | Dna-adapter-molecules for the preparation of dna-libraries and method for producing them and use |
| US9551697B2 (en) | 2013-10-17 | 2017-01-24 | Genia Technologies, Inc. | Non-faradaic, capacitively coupled measurement in a nanopore cell array |
| CN105723222B (zh) | 2013-10-23 | 2019-01-22 | 吉尼亚科技公司 | 使用纳米孔的高速分子感测 |
| US9567630B2 (en) | 2013-10-23 | 2017-02-14 | Genia Technologies, Inc. | Methods for forming lipid bilayers on biochips |
| HUE051262T2 (hu) * | 2014-01-28 | 2021-03-01 | Lanzatech New Zealand Ltd | Módszer rekombináns mirkoorganizmus elõállítására |
| DK3604544T3 (en) * | 2014-01-31 | 2022-02-14 | Swift Biosciences Inc | Improved methods for processing dna substrates |
| US10179932B2 (en) | 2014-07-11 | 2019-01-15 | President And Fellows Of Harvard College | Methods for high-throughput labelling and detection of biological features in situ using microscopy |
| JP2017525369A (ja) | 2014-09-05 | 2017-09-07 | キアゲン ゲーエムベーハー | アダプター連結アンプリコンの調製 |
| WO2016037358A1 (zh) | 2014-09-12 | 2016-03-17 | 深圳华大基因科技有限公司 | 分离的寡核苷酸及其在核酸测序中的用途 |
| US20180044668A1 (en) * | 2014-10-14 | 2018-02-15 | Bgi Shenzhen Co., Limited | Mate pair library construction |
| WO2016058136A1 (zh) * | 2014-10-14 | 2016-04-21 | 深圳华大基因科技有限公司 | 一种接头元件和使用其构建测序文库的方法 |
| US10221448B2 (en) | 2015-03-06 | 2019-03-05 | Pillar Biosciences Inc. | Selective amplification of overlapping amplicons |
| CN106435744B (zh) * | 2015-08-13 | 2022-02-01 | 生捷科技控股公司 | 使用y-接头和消失限制位点的文库构建 |
| GB2559526B (en) | 2015-11-03 | 2021-02-17 | Harvard College | Method and apparatus for volumetric imaging of a three-dimensional nucleic acid containing matrix |
| CA3006994A1 (en) | 2015-12-16 | 2017-06-22 | Fluidigm Corporation | High-level multiplex amplification |
| WO2017156336A1 (en) | 2016-03-10 | 2017-09-14 | The Board Of Trustees Of The Leland Stanford Junior University | Transposase-mediated imaging of the accessible genome |
| EP4613756A3 (en) | 2016-04-25 | 2025-11-12 | President And Fellows Of Harvard College | Hybridization chain reaction methods for in situ molecular detection |
| EP3485035B1 (en) * | 2016-07-15 | 2024-07-03 | The Regents of the University of California | Methods of producing nucleic acid libraries |
| GB2570412A (en) | 2016-08-31 | 2019-07-24 | Harvard College | Methods of generating libraries of nucleic acid sequences for detection via fluorescent in situ sequencing |
| CN118853848A (zh) | 2016-08-31 | 2024-10-29 | 哈佛学院董事及会员团体 | 将生物分子的检测组合到使用荧光原位测序的单个试验的方法 |
| US10550425B2 (en) * | 2016-11-14 | 2020-02-04 | Agilent Technologies, Inc. | Composition and method for improving signal-to-noise in hybridization to oligonucleotide arrays |
| EP3513346B1 (en) * | 2016-11-30 | 2020-04-15 | Microsoft Technology Licensing, LLC | Dna random access storage system via ligation |
| CN109789167A (zh) | 2017-04-14 | 2019-05-21 | 哈佛学院董事及会员团体 | 用于产生细胞衍生的微丝网络的方法 |
| CN107299151B (zh) * | 2017-08-28 | 2020-06-09 | 华中农业大学 | 用于鉴别稻米脂肪酸品质的dna分子标记及其应用 |
| JP7296969B2 (ja) | 2018-01-12 | 2023-06-23 | クラレット バイオサイエンス, エルエルシー | 核酸を解析するための方法および組成物 |
| CN119020348A (zh) | 2018-02-05 | 2024-11-26 | 斯坦福大学托管董事会 | 用于单细胞和集合细胞的多重测量的系统和方法 |
| WO2019236726A1 (en) | 2018-06-06 | 2019-12-12 | The Regents Of The University Of California | Methods of producing nucleic acid libraries and compositions and kits for practicing same |
| SG11202101934SA (en) | 2018-07-30 | 2021-03-30 | Readcoor Llc | Methods and systems for sample processing or analysis |
| WO2020076976A1 (en) | 2018-10-10 | 2020-04-16 | Readcoor, Inc. | Three-dimensional spatial molecular indexing |
| US20220049303A1 (en) | 2020-08-17 | 2022-02-17 | Readcoor, Llc | Methods and systems for spatial mapping of genetic variants |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5102785A (en) * | 1987-09-28 | 1992-04-07 | E. I. Du Pont De Nemours And Company | Method of gene mapping |
| JPH02299598A (ja) * | 1989-04-14 | 1990-12-11 | Ro Inst For Molecular Genetics & Geneteic Res | 微視的サイズの別個の粒子と結合している核酸試料中のごく短い配列の全部または一部のオリゴヌクレチドプローブとのハイブリダイゼーションによる決定法 |
| US5650274A (en) * | 1993-06-25 | 1997-07-22 | Hitachi, Ltd. | DNA analyzing method |
| GB9401200D0 (en) * | 1994-01-21 | 1994-03-16 | Medical Res Council | Sequencing of nucleic acids |
| US5552278A (en) * | 1994-04-04 | 1996-09-03 | Spectragen, Inc. | DNA sequencing by stepwise ligation and cleavage |
| US5604097A (en) * | 1994-10-13 | 1997-02-18 | Spectragen, Inc. | Methods for sorting polynucleotides using oligonucleotide tags |
| HUP9900910A2 (hu) * | 1995-06-07 | 1999-07-28 | Lynx Therapeutics, Inc. | Oligonukleotid jelzések osztályozáshoz és azonosításhoz |
-
1997
- 1997-06-02 JP JP50075598A patent/JP4124377B2/ja not_active Expired - Lifetime
- 1997-06-02 CA CA002256700A patent/CA2256700A1/en not_active Abandoned
- 1997-06-02 AT AT97929757T patent/ATE356221T1/de not_active IP Right Cessation
- 1997-06-02 CN CNB971971013A patent/CN1195872C/zh not_active Expired - Lifetime
- 1997-06-02 AU AU33740/97A patent/AU733782B2/en not_active Ceased
- 1997-06-02 WO PCT/US1997/009472 patent/WO1997046704A1/en not_active Ceased
- 1997-06-02 HU HU0003944A patent/HUP0003944A3/hu not_active Application Discontinuation
- 1997-06-02 CZ CZ983979A patent/CZ397998A3/cs unknown
- 1997-06-02 EP EP97929757A patent/EP0923650B1/en not_active Expired - Lifetime
- 1997-06-02 PL PL97331513A patent/PL331513A1/xx unknown
- 1997-06-02 DE DE69737450T patent/DE69737450T2/de not_active Expired - Lifetime
-
1998
- 1998-12-04 NO NO985698A patent/NO985698L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| AU733782B2 (en) | 2001-05-24 |
| CN1230226A (zh) | 1999-09-29 |
| NO985698D0 (no) | 1998-12-04 |
| PL331513A1 (en) | 1999-07-19 |
| JP4124377B2 (ja) | 2008-07-23 |
| EP0923650B1 (en) | 2007-03-07 |
| HK1021206A1 (en) | 2000-06-02 |
| DE69737450D1 (de) | 2007-04-19 |
| EP0923650A1 (en) | 1999-06-23 |
| CZ397998A3 (cs) | 1999-07-14 |
| CN1195872C (zh) | 2005-04-06 |
| JP2000515006A (ja) | 2000-11-14 |
| HUP0003944A2 (en) | 2001-03-28 |
| NO985698L (no) | 1999-02-08 |
| DE69737450T2 (de) | 2007-11-29 |
| WO1997046704A1 (en) | 1997-12-11 |
| CA2256700A1 (en) | 1997-12-11 |
| HUP0003944A3 (en) | 2003-08-28 |
| AU3374097A (en) | 1998-01-05 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE356221T1 (de) | Sequenzierung durch ligation kodierter adapter | |
| ATE201238T1 (de) | Dns-sequenzierung durch stufenweise ligierung und spaltung | |
| DK0970240T3 (da) | Kunstig fejlparringshydridisering | |
| NO961165L (no) | Fremgangsmåte og kit for effektiv sekvensering av nukleinsyre | |
| MX9705961A (es) | Polimerasa de adn termoestable, modificada. | |
| ATE164883T1 (de) | Verfahren zur vorbereitung von doppel strangiger rna und seine anwendungen | |
| CA2218017A1 (en) | Dna sequencing by parallel oligonucleotide extensions | |
| CA2218476A1 (en) | Diagnostic method | |
| WO2002068579A3 (en) | Kits, such as nucleic acid arrays, comprising a majority of human exons or transcripts, for detecting expression and other uses thereof | |
| DE69516116D1 (de) | Sequenzierung von nukleinsäuren | |
| DE69924140D1 (de) | Bestimmung der länge von repetitiven nukleinsäuresequenzen durch eine diskontinuierliche verlängerung von startermolekülen | |
| ATE241018T1 (de) | Untersuchung von nukleotiden in loesung mit hilfe von pna-sonden | |
| ATE160822T1 (de) | Identifizierung von salmonella durch die polymerase-ketten-reaktion | |
| DE60204874D1 (de) | Verfahren zur nachweis von nukleinsäuren | |
| AU1204600A (en) | Systems and methods for sequencing by hybridization | |
| ATE195974T1 (de) | Nukleotidsequenzen die spezifisch mit einer nukleotidsequenz aus campylobacter jejuni hybridisieren | |
| HK1054572A1 (en) | Method of generation and management of unique sequences in dna production | |
| AU2002215010A1 (en) | Thermostable polymerase based on thermococcus pacificus | |
| CN119932729A (zh) | 甲基化文库的构建方法及试剂盒 | |
| WO2001040510A3 (de) | Dynamische sequenzierung durch hybridisierung |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |