ATE356200T1 - Kcnq kaliumkanäle und verfahren zur deren modulierung - Google Patents

Kcnq kaliumkanäle und verfahren zur deren modulierung

Info

Publication number
ATE356200T1
ATE356200T1 AT98932877T AT98932877T ATE356200T1 AT E356200 T1 ATE356200 T1 AT E356200T1 AT 98932877 T AT98932877 T AT 98932877T AT 98932877 T AT98932877 T AT 98932877T AT E356200 T1 ATE356200 T1 AT E356200T1
Authority
AT
Austria
Prior art keywords
kcnq2
proteins
kcnq3
potassium channels
disease
Prior art date
Application number
AT98932877T
Other languages
English (en)
Inventor
Michael A Blanar
Steven Dworetzky
Wen-Pin Yang
Paul C Levesque
Valentin K Gribkoff
Michael G Neubauer
Wayne A Little
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21998937&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE356200(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Application granted granted Critical
Publication of ATE356200T1 publication Critical patent/ATE356200T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Steroid Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT98932877T 1997-08-12 1998-06-26 Kcnq kaliumkanäle und verfahren zur deren modulierung ATE356200T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US5559997P 1997-08-12 1997-08-12

Publications (1)

Publication Number Publication Date
ATE356200T1 true ATE356200T1 (de) 2007-03-15

Family

ID=21998937

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98932877T ATE356200T1 (de) 1997-08-12 1998-06-26 Kcnq kaliumkanäle und verfahren zur deren modulierung

Country Status (10)

Country Link
US (4) US6403360B1 (de)
EP (1) EP1007638B1 (de)
JP (1) JP2001512673A (de)
AT (1) ATE356200T1 (de)
AU (1) AU731087B2 (de)
CA (1) CA2300985A1 (de)
DE (1) DE69837267T2 (de)
DK (1) DK1007638T3 (de)
ES (1) ES2281129T3 (de)
WO (1) WO1999007832A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2281129T3 (es) * 1997-08-12 2007-09-16 Bristol-Myers Squibb Company Canales de potasio kcnq y procedimientos para su modulacion.
US6413719B1 (en) 1997-10-24 2002-07-02 University Of Utah Research Foundation KCNQ2 and KCNQ3-potassium channel genes which are mutated in benign familial neonatal convulsions (BFNC) and other epilepsies
JP2002543768A (ja) * 1999-04-14 2002-12-24 メルク エンド カムパニー インコーポレーテッド 新規ヒト電位依存性カリウムチャンネル
US6649371B1 (en) 1999-06-11 2003-11-18 Neurosearch A/S Potassium channel KCNQ5 and sequences encoding the same
JP4833467B2 (ja) * 1999-06-11 2011-12-07 ニューロサーチ、アクティーゼルスカブ 新規カリウムチャネル及び同カリウムチャネルをコードする遺伝子
US6472165B1 (en) 1999-08-03 2002-10-29 Arzneimittelwerk Dresden Gmbh Modulatory binding site in potassium channels for screening and finding new active ingredients
JP2003506388A (ja) 1999-08-04 2003-02-18 アイカゲン インコーポレイテッド 疼痛および不安症を処置または予防するための方法
DE10013732A1 (de) * 2000-03-21 2001-09-27 Aventis Pharma Gmbh Das Kaliumkanalprotein KCNQ5, ein neuer Angriffspunkt bei Erkrankungen des zentralen Nervensystems und des Herz-Kreislauf-Systems
US6617131B2 (en) 2000-03-21 2003-09-09 Aventis Pharma Deutschland Gmbh Nucleic acid molecule encoding the potassium channel protein, KCNQ5
US7049137B2 (en) 2000-03-21 2006-05-23 Icagen, Inc. KCNQ5, a novel potassium channel
US6767736B2 (en) * 2000-04-03 2004-07-27 Lexicon Genetics Incorporated Human ion channel protein and polynucleotides encoding the same
US6893858B2 (en) * 2000-05-26 2005-05-17 Bristol-Myers Squibb Company Human kcnq5 potassium channel, methods and compositions thereof
US6348486B1 (en) * 2000-10-17 2002-02-19 American Home Products Corporation Methods for modulating bladder function
WO2002072088A2 (en) * 2001-02-20 2002-09-19 Bristol-Myers Squibb Company Modulators of kcnq potassium channels and use thereof in treating migraine and mechanistically related diseases
RU2607033C2 (ru) * 2010-09-28 2017-01-10 Ноно Инк. Пептиды nd2 и способы лечения неврологического заболевания
FR3029113A1 (fr) * 2014-12-02 2016-06-03 Univ Paris-Sud Composes pour le traitement des maladies mitochondriales
US20230124616A1 (en) * 2020-03-06 2023-04-20 Ionis Pharmaceuticals, Inc. Compounds and methods for modulating kcnq2

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09191882A (ja) * 1996-01-16 1997-07-29 Japan Tobacco Inc ヒト新規ｋ＋チャネル蛋白質をコードするｄｎａおよびその断片
ES2281129T3 (es) * 1997-08-12 2007-09-16 Bristol-Myers Squibb Company Canales de potasio kcnq y procedimientos para su modulacion.
US6413719B1 (en) * 1997-10-24 2002-07-02 University Of Utah Research Foundation KCNQ2 and KCNQ3-potassium channel genes which are mutated in benign familial neonatal convulsions (BFNC) and other epilepsies

Also Published As

Publication number Publication date
CA2300985A1 (en) 1999-02-18
ES2281129T3 (es) 2007-09-16
WO1999007832A1 (en) 1999-02-18
US7262289B2 (en) 2007-08-28
US6403360B1 (en) 2002-06-11
DE69837267T2 (de) 2007-10-31
US20030044912A1 (en) 2003-03-06
JP2001512673A (ja) 2001-08-28
DK1007638T3 (da) 2007-05-21
US7041496B2 (en) 2006-05-09
EP1007638B1 (de) 2007-03-07
AU731087B2 (en) 2001-03-22
US7482431B2 (en) 2009-01-27
US20070148692A1 (en) 2007-06-28
EP1007638A1 (de) 2000-06-14
US20020168724A1 (en) 2002-11-14
DE69837267D1 (de) 2007-04-19
AU8266598A (en) 1999-03-01
EP1007638A4 (de) 2004-12-29

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