DE69837267D1 - Kcnq kaliumkanäle und verfahren zur deren modulierung - Google Patents

Kcnq kaliumkanäle und verfahren zur deren modulierung

Info

Publication number
DE69837267D1
DE69837267D1 DE69837267T DE69837267T DE69837267D1 DE 69837267 D1 DE69837267 D1 DE 69837267D1 DE 69837267 T DE69837267 T DE 69837267T DE 69837267 T DE69837267 T DE 69837267T DE 69837267 D1 DE69837267 D1 DE 69837267D1
Authority
DE
Germany
Prior art keywords
kcnq2
proteins
kcnq3
kcnq
channels
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Revoked
Application number
DE69837267T
Other languages
English (en)
Other versions
DE69837267T2 (de
Inventor
Michael A Blanar
Steven Dworetzky
Wen-Pin Yang
Paul C Levesque
Valentin K Gribkoff
Michael G Neubauer
Wayne A Little
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Squibb Co
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21998937&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69837267(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of DE69837267D1 publication Critical patent/DE69837267D1/de
Application granted granted Critical
Publication of DE69837267T2 publication Critical patent/DE69837267T2/de
Anticipated expiration legal-status Critical
Revoked legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DE69837267T 1997-08-12 1998-06-26 Kcnq kaliumkanäle und verfahren zur deren modulierung Revoked DE69837267T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US5559997P 1997-08-12 1997-08-12
US55599P 1997-08-12
PCT/US1998/013276 WO1999007832A1 (en) 1997-08-12 1998-06-26 Kcnq potassium channels and methods of modulating same

Publications (2)

Publication Number Publication Date
DE69837267D1 true DE69837267D1 (de) 2007-04-19
DE69837267T2 DE69837267T2 (de) 2007-10-31

Family

ID=21998937

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69837267T Revoked DE69837267T2 (de) 1997-08-12 1998-06-26 Kcnq kaliumkanäle und verfahren zur deren modulierung

Country Status (10)

Country Link
US (4) US6403360B1 (de)
EP (1) EP1007638B1 (de)
JP (1) JP2001512673A (de)
AT (1) ATE356200T1 (de)
AU (1) AU731087B2 (de)
CA (1) CA2300985A1 (de)
DE (1) DE69837267T2 (de)
DK (1) DK1007638T3 (de)
ES (1) ES2281129T3 (de)
WO (1) WO1999007832A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1007638T3 (da) * 1997-08-12 2007-05-21 Bristol Myers Squibb Co KCNQ-kaliumkanaler og fremgangsmåde til modulering deraf
EP1037900A4 (de) * 1997-10-24 2006-08-30 Univ Utah Res Found Kcnq2 und kcnq3-kaliumkanalgene welche als mutanten bei gutartigen krämpfen bei neugeborenen und anderen formen von epilepsie vorliegen
WO2000061606A1 (en) * 1999-04-14 2000-10-19 Merck & Co., Inc. Novel human voltage-gated potassium channel
US6649371B1 (en) * 1999-06-11 2003-11-18 Neurosearch A/S Potassium channel KCNQ5 and sequences encoding the same
JP4833467B2 (ja) * 1999-06-11 2011-12-07 ニューロサーチ、アクティーゼルスカブ 新規カリウムチャネル及び同カリウムチャネルをコードする遺伝子
US6472165B1 (en) * 1999-08-03 2002-10-29 Arzneimittelwerk Dresden Gmbh Modulatory binding site in potassium channels for screening and finding new active ingredients
EP1200086A4 (de) 1999-08-04 2009-05-27 Icagen Inc Methoden zur behandlung oder vorbeugung von schmerzen und angstzuständen
US6617131B2 (en) 2000-03-21 2003-09-09 Aventis Pharma Deutschland Gmbh Nucleic acid molecule encoding the potassium channel protein, KCNQ5
DE10013732A1 (de) * 2000-03-21 2001-09-27 Aventis Pharma Gmbh Das Kaliumkanalprotein KCNQ5, ein neuer Angriffspunkt bei Erkrankungen des zentralen Nervensystems und des Herz-Kreislauf-Systems
US7049137B2 (en) 2000-03-21 2006-05-23 Icagen, Inc. KCNQ5, a novel potassium channel
EP1272634A1 (de) * 2000-04-03 2003-01-08 Lexicon Genetics Incorporated Humaner ionenkanal und polynukleotide dafür
US6893858B2 (en) * 2000-05-26 2005-05-17 Bristol-Myers Squibb Company Human kcnq5 potassium channel, methods and compositions thereof
TWI287984B (en) * 2000-10-17 2007-10-11 Wyeth Corp Pharmaceutical composition for modulating bladder function
WO2002072088A2 (en) * 2001-02-20 2002-09-19 Bristol-Myers Squibb Company Modulators of kcnq potassium channels and use thereof in treating migraine and mechanistically related diseases
DK2621945T3 (en) * 2010-09-28 2018-05-22 Nono Inc ND2 PEPTIDES AND METHODS OF TREATING NEUROLOGICAL DISEASE
FR3029113A1 (fr) * 2014-12-02 2016-06-03 Univ Paris-Sud Composes pour le traitement des maladies mitochondriales
WO2021178769A1 (en) * 2020-03-06 2021-09-10 Ionis Pharmaceuticals, Inc. Compounds and methods for modulating kcnq2

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09191882A (ja) 1996-01-16 1997-07-29 Japan Tobacco Inc ヒト新規ｋ＋チャネル蛋白質をコードするｄｎａおよびその断片
DK1007638T3 (da) * 1997-08-12 2007-05-21 Bristol Myers Squibb Co KCNQ-kaliumkanaler og fremgangsmåde til modulering deraf
EP1037900A4 (de) * 1997-10-24 2006-08-30 Univ Utah Res Found Kcnq2 und kcnq3-kaliumkanalgene welche als mutanten bei gutartigen krämpfen bei neugeborenen und anderen formen von epilepsie vorliegen

Also Published As

Publication number Publication date
CA2300985A1 (en) 1999-02-18
JP2001512673A (ja) 2001-08-28
US20030044912A1 (en) 2003-03-06
AU731087B2 (en) 2001-03-22
US20070148692A1 (en) 2007-06-28
US20020168724A1 (en) 2002-11-14
ES2281129T3 (es) 2007-09-16
US6403360B1 (en) 2002-06-11
US7482431B2 (en) 2009-01-27
AU8266598A (en) 1999-03-01
US7041496B2 (en) 2006-05-09
ATE356200T1 (de) 2007-03-15
DK1007638T3 (da) 2007-05-21
EP1007638A1 (de) 2000-06-14
US7262289B2 (en) 2007-08-28
EP1007638A4 (de) 2004-12-29
DE69837267T2 (de) 2007-10-31
EP1007638B1 (de) 2007-03-07
WO1999007832A1 (en) 1999-02-18

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Legal Events

Date Code Title Description
8363 Opposition against the patent
8331 Complete revocation