ATE345355T1 - Peptidkonjugate, deren derivate mit metallischen komplexen und deren verwendung zur bildgebenden magnetischen resonanz - Google Patents
Peptidkonjugate, deren derivate mit metallischen komplexen und deren verwendung zur bildgebenden magnetischen resonanzInfo
- Publication number
- ATE345355T1 ATE345355T1 AT02764797T AT02764797T ATE345355T1 AT E345355 T1 ATE345355 T1 AT E345355T1 AT 02764797 T AT02764797 T AT 02764797T AT 02764797 T AT02764797 T AT 02764797T AT E345355 T1 ATE345355 T1 AT E345355T1
- Authority
- AT
- Austria
- Prior art keywords
- magnetic resonance
- derivatives
- resonance imaging
- metal complexes
- peptide conjugates
- Prior art date
Links
- 238000002595 magnetic resonance imaging Methods 0.000 title 1
- 239000002184 metal Substances 0.000 title 1
- 239000000863 peptide conjugate Substances 0.000 title 1
- 108050001286 Somatostatin Receptor Proteins 0.000 abstract 2
- 102000011096 Somatostatin receptor Human genes 0.000 abstract 2
- 102000004859 Cholecystokinin Receptors Human genes 0.000 abstract 1
- 108090001085 Cholecystokinin Receptors Proteins 0.000 abstract 1
- 206010027476 Metastases Diseases 0.000 abstract 1
- 238000005481 NMR spectroscopy Methods 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 239000002872 contrast media Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/10—Organic compounds
- A61K49/14—Peptides, e.g. proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/085—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier conjugated systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/595—Gastrins; Cholecystokinins [CCK]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/655—Somatostatins
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Radiology & Medical Imaging (AREA)
- Toxicology (AREA)
- Endocrinology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT2001MI001708A ITMI20011708A1 (it) | 2001-08-03 | 2001-08-03 | Coniugati di peptidi, loro derivati con complessi metallici e utilizzo per i'indagine diagnostica tramite imaging per risonanza magnetica(m |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE345355T1 true ATE345355T1 (de) | 2006-12-15 |
Family
ID=11448231
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02764797T ATE345355T1 (de) | 2001-08-03 | 2002-07-26 | Peptidkonjugate, deren derivate mit metallischen komplexen und deren verwendung zur bildgebenden magnetischen resonanz |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20050008573A1 (de) |
| EP (1) | EP1412383B9 (de) |
| JP (1) | JP4216715B2 (de) |
| AT (1) | ATE345355T1 (de) |
| AU (1) | AU2002328981A1 (de) |
| DE (1) | DE60216111T2 (de) |
| IT (1) | ITMI20011708A1 (de) |
| WO (1) | WO2003014157A2 (de) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ITPD20030174A1 (it) * | 2003-07-31 | 2003-10-29 | Univ Padova | Coniugati polimerici per diagnostica e terapia |
| ATE430146T1 (de) | 2004-07-02 | 2009-05-15 | Bracco Imaging Spa | Kontrastmittel mit hoher relaxivität zur verwendung in der magnetresonanzbilddarstellung (mri), enthaltend eine chelatbildende gruppe mit polyhydroxylierten substituenten |
| EP1898958A2 (de) * | 2005-05-31 | 2008-03-19 | INBIOS S.r.l. | Supramolekulare aggregate mit cheliermitteln und bioaktiven peptiden als effektive und selektive abgabewerkzeuge für arzneimittel und kontrastmittel bei mrt oder in der nuklearmedizin |
| US9339559B2 (en) | 2005-09-09 | 2016-05-17 | Georgia State University Research Foundation, Inc. | Targeted contrast agents and methods for targeting contrast agents |
| CA2621763C (en) * | 2005-09-09 | 2021-04-06 | Georgia State University Research Foundation, Inc. | Targeted contrast agents and methods for targeting contrast agents |
| WO2007111514A1 (en) * | 2006-03-29 | 2007-10-04 | Ge Healthcare As | Contrast agents for magnetic resonance imaging and spectroscopy consisting of a cyclic oligoamid core of 3 to 4 identical monomer units with 3 to 4 paramagnetic chelate side chains |
| WO2008019123A2 (en) | 2006-08-04 | 2008-02-14 | Georgia State University Research Foundation, Inc. | Enzyme sensors, methods for preparing and using such sensors, and methods of detecting protease activity |
| US8288530B2 (en) | 2006-11-06 | 2012-10-16 | The United States Of America, As Represented By The Department Of Health And Human Services | Method of preparing macromolecular contrast agents and uses thereof |
| WO2008076365A2 (en) | 2006-12-14 | 2008-06-26 | Georgia State University Research Foundation, Inc. | Analyte sensors, methods for preparing and using such sensors, and methods of detecting analyte activity |
| EP2257316B1 (de) * | 2008-04-02 | 2018-11-07 | Georgia State University Research Foundation, Inc. | Kontrastmittel, verfahren zur herstellung von kontrastmitteln und abbildungsverfahren |
| US20110038805A1 (en) * | 2008-04-18 | 2011-02-17 | Andreas Meijer | Compounds comprising paramagnetic chelates arranged around a central core and their use in magneto resonance imaging and spectroscopy |
| ES2354320B2 (es) * | 2008-06-24 | 2011-10-11 | Universidade De Santiago De Compostela | Ciclopéptidos marcados magnéticamente con complejos de lantánidos. |
| EP3027228B1 (de) | 2013-08-01 | 2024-10-02 | Rochester Institute of Technology | Modulare kontrastmittel mit aminosäuren und peptiden |
| US10265014B2 (en) * | 2013-09-06 | 2019-04-23 | Somnology, Inc. | System and method for sleep disorder diagnosis and treatment |
| US10265013B2 (en) * | 2013-09-06 | 2019-04-23 | Somnology, Inc. | System and method for sleep disorder diagnosis and treatment |
| EP3101012A1 (de) | 2015-06-04 | 2016-12-07 | Bayer Pharma Aktiengesellschaft | Neue gadoliniumchelat-verbindung zur verwendung in der magnetresonanzbildgebung |
| EP3389478B1 (de) | 2015-12-15 | 2021-03-31 | Mayo Foundation for Medical Education and Research | Systeme und verfahren zum linearen zeitlichen clustering für begrenzte, wiederholbare, seltene ereignisse in physiologischen signalen |
| JP7034160B2 (ja) | 2016-11-28 | 2022-03-11 | バイエル・ファルマ・アクティエンゲゼルシャフト | 磁気共鳴画像法に使用するための高緩和度ガドリニウムキレート化合物 |
| PE20211471A1 (es) | 2018-11-23 | 2021-08-05 | Bayer Ag | Formulacion de medios de contraste y proceso para prepararlos |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9111199D0 (en) * | 1991-05-23 | 1991-07-17 | Sandoz Ltd | Improvements in or relating to organic compounds |
| US5364613A (en) * | 1989-04-07 | 1994-11-15 | Sieving Paul F | Polychelants containing macrocyclic chelant moieties |
| GB9215780D0 (en) * | 1992-07-24 | 1992-09-09 | Univ London Pharmacy | Peptide compounds |
| CA2113121A1 (en) * | 1993-01-12 | 1994-07-13 | Rainer Albert | Peptides |
| GB9404208D0 (en) * | 1994-03-04 | 1994-04-20 | Nycomed Salutar Inc | Chelants |
| GB9417873D0 (en) * | 1994-09-06 | 1994-10-26 | Sandoz Ltd | Organic compounds |
| US5762909A (en) * | 1995-08-31 | 1998-06-09 | General Electric Company | Tumor targeting with polymeric molecules having extended conformation |
| AT405906B (de) * | 1997-03-14 | 1999-12-27 | Irene Dr Virgolini | Radiomarkierte somatostatin rezeptor-liganden zur diagnose und therapie |
| US6342598B1 (en) * | 1998-11-26 | 2002-01-29 | Bracco International B.V. | Amphipatic polycarboxylic chelates and complexes with paramagnetic metals as MRI contrast agents |
| IT1315263B1 (it) * | 1999-12-21 | 2003-02-03 | Bracco Spa | Composti chelanti,loro chelati con ioni metallici paramagnetici, loropreparazione ed uso |
-
2001
- 2001-08-03 IT IT2001MI001708A patent/ITMI20011708A1/it unknown
-
2002
- 2002-07-26 US US10/485,847 patent/US20050008573A1/en not_active Abandoned
- 2002-07-26 AU AU2002328981A patent/AU2002328981A1/en not_active Abandoned
- 2002-07-26 WO PCT/EP2002/008382 patent/WO2003014157A2/en active IP Right Grant
- 2002-07-26 DE DE60216111T patent/DE60216111T2/de not_active Expired - Lifetime
- 2002-07-26 AT AT02764797T patent/ATE345355T1/de not_active IP Right Cessation
- 2002-07-26 EP EP02764797A patent/EP1412383B9/de not_active Expired - Lifetime
- 2002-07-26 JP JP2003519106A patent/JP4216715B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ITMI20011708A1 (it) | 2003-02-03 |
| DE60216111D1 (de) | 2006-12-28 |
| WO2003014157A2 (en) | 2003-02-20 |
| WO2003014157A3 (en) | 2003-11-13 |
| JP2005510461A (ja) | 2005-04-21 |
| US20050008573A1 (en) | 2005-01-13 |
| EP1412383B1 (de) | 2006-11-15 |
| JP4216715B2 (ja) | 2009-01-28 |
| EP1412383B9 (de) | 2007-10-03 |
| AU2002328981A1 (en) | 2003-02-24 |
| EP1412383A2 (de) | 2004-04-28 |
| ITMI20011708A0 (it) | 2001-08-03 |
| DE60216111T2 (de) | 2007-04-05 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE345355T1 (de) | Peptidkonjugate, deren derivate mit metallischen komplexen und deren verwendung zur bildgebenden magnetischen resonanz | |
| PT907379E (pt) | Agentes de contraste bioactivados para imagiologia de diagnostico | |
| CY1117387T1 (el) | ΜΟΝΟΚΛΩΝΙΚΑ ΑΝΤΙΣΩΜΑΤΑ Ν-11 ΔΙΑΣΠΑΣΜΕΝΟΥ β-ΑΜΥΛΟΕΙΔΟΥΣ, ΣΥΝΘΕΣΕΙΣ, ΜΕΘΟΔΟΙ ΚΑΙ ΧΡΗΣΕΙΣ | |
| ATE489108T1 (de) | Flt4 (vegfr-3) als ziel für tumornachweis (imaging) und antitumortherapie | |
| CY1112055T1 (el) | Συνθεσεις και μεθοδοι για την διαγνωση και θεραπευτικη αγωγη ογκου πνευμονα | |
| IL168058A (en) | Antibody preferentially linked to cell Ca125 / 0722p relative to ca125 / 0722p deciduous cell, the pharmaceutical composition containing it and its use in the preparation of a drug | |
| ATE527552T1 (de) | Mr-darstellungsverfahren zur diskriminierung zwischen gesundem und tumorgewebe | |
| ATE307540T1 (de) | Magnetresonanzkompatible metallische endoprothese | |
| SE8904087D0 (sv) | Peptide derivates | |
| UY28337A1 (es) | Anticuerpos humanizados que reconocen el peptido beta amiloide | |
| ATE352567T1 (de) | Herstellung von agonisten und antagonisten von cholecystokinin und ihre therapeutische und diagnostische verwendung | |
| CY1106662T1 (el) | Αντι-igf-ir αντισωματα και οι εφαρμογες τους | |
| ATE298763T1 (de) | Integrinbindende peptidderivate | |
| MY136095A (en) | Use of human anti-ctla-4 antibodies for treatment of cancer | |
| DE60035240D1 (de) | Marker für Computertomografie und MRI-Bilderzeugung | |
| DE60136054D1 (de) | Apoptose-induzierendes polypeptid | |
| DE69837273D1 (de) | Menschliches krebsantigen ny eso-1/cag-3 und dazu kodierendes gen | |
| Nedrow et al. | Positron emission tomographic imaging of copper 64–and gallium 68–labeled chelator conjugates of the somatostatin agonist Tyr3-octreotate | |
| GEP20053423B (en) | Method of Inhibiting Amyloid Protein Aggregation and Method for Imaging of Amyloid Deposits | |
| TR200103786T2 (tr) | Güğüs kanserinin tehisi ve imünoterapisi için bileşikler ve bunların kullanımı | |
| DE60014064D1 (de) | Einetenascin-c isoform als marker für neoplasmen | |
| ATE419861T1 (de) | Peptide mit homing für lymphgefässtumor und ihre verwendung | |
| DE59709109D1 (de) | Monoklonale antikörper gegen einen komplex aus humanem act und einer serinprotease | |
| DK1001977T3 (da) | Radioaktivt mærkede peptider til diagnosen og behandlingen af bryst- og prostatatumorer samt metastaser af sådanne tumorer | |
| ATE254130T1 (de) | Makrozyclische liganden für metallpharmazeutika |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |