BRPI0417451A - método de tratar um tumor resistente a interferon - Google Patents
método de tratar um tumor resistente a interferonInfo
- Publication number
- BRPI0417451A BRPI0417451A BRPI0417451-8A BRPI0417451A BRPI0417451A BR PI0417451 A BRPI0417451 A BR PI0417451A BR PI0417451 A BRPI0417451 A BR PI0417451A BR PI0417451 A BRPI0417451 A BR PI0417451A
- Authority
- BR
- Brazil
- Prior art keywords
- interferon
- treating
- recombinant vectors
- resistant tumor
- present
- Prior art date
Links
- 102000014150 Interferons Human genes 0.000 title abstract 8
- 108010050904 Interferons Proteins 0.000 title abstract 8
- 229940079322 interferon Drugs 0.000 title abstract 6
- 206010028980 Neoplasm Diseases 0.000 title abstract 4
- 239000013598 vector Substances 0.000 abstract 3
- 229940047124 interferons Drugs 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/0008—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
- A61K38/212—IFN-alpha
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/555—Interferons [IFN]
- C07K14/56—IFN-alpha
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10341—Use of virus, viral particle or viral elements as a vector
- C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Toxicology (AREA)
- Immunology (AREA)
- Virology (AREA)
- Physics & Mathematics (AREA)
- Dispersion Chemistry (AREA)
- Reproductive Health (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Gynecology & Obstetrics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
"MéTODO DE TRATAR UM TUMOR RESISTENTE A INTERFERON". A presente invenção fornece um método para o tratamento de tumores resistentes a interferon, através do uso de vetores recombinantes codificando espécie de interferon. Em particular é observado que a espécie de interferon, provida por vetores recombinantes, possui propriedades não associadas com as proteínas de interferon recombinantemente produzidas. A presente invenção provê ainda composições úteis no tratamento de tumores resistentes a interferon, empregando vetores recombinantes codificando interferons.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US52852503P | 2003-12-10 | 2003-12-10 | |
PCT/US2004/041307 WO2005058368A1 (en) | 2003-12-10 | 2004-12-10 | Methods and compositions for treatment of interferon-resistant tumors |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0417451A true BRPI0417451A (pt) | 2007-04-10 |
Family
ID=34699875
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0417451-8A BRPI0417451A (pt) | 2003-12-10 | 2004-12-10 | método de tratar um tumor resistente a interferon |
Country Status (17)
Country | Link |
---|---|
US (7) | US7691822B2 (pt) |
EP (2) | EP2301584A1 (pt) |
JP (2) | JP4801594B2 (pt) |
KR (1) | KR101163248B1 (pt) |
CN (1) | CN1893981B (pt) |
AT (1) | ATE502654T1 (pt) |
AU (1) | AU2004298991A1 (pt) |
BR (1) | BRPI0417451A (pt) |
CA (1) | CA2548100C (pt) |
DE (1) | DE602004031973D1 (pt) |
ES (1) | ES2363912T3 (pt) |
HK (1) | HK1095525A1 (pt) |
IL (1) | IL175820A0 (pt) |
NO (1) | NO20062385L (pt) |
SG (2) | SG166117A1 (pt) |
WO (1) | WO2005058368A1 (pt) |
ZA (1) | ZA200604640B (pt) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5789244A (en) * | 1996-01-08 | 1998-08-04 | Canji, Inc. | Compositions and methods for the treatment of cancer using recombinant viral vector delivery systems |
US7002027B1 (en) * | 1996-01-08 | 2006-02-21 | Canji, Inc. | Compositions and methods for therapeutic use |
PT1456377T (pt) * | 2001-12-20 | 2019-09-10 | Merck Sharp & Dohme | Composições de syn3 e processos |
CN101396555A (zh) * | 2003-06-04 | 2009-04-01 | 坎基股份有限公司 | 用于干扰素治疗的方法和组合物 |
JP4801594B2 (ja) * | 2003-12-10 | 2011-10-26 | カンジ,インコーポレイテッド | インターフェロン耐性腫瘍の処置のための方法および組成物 |
ATE516343T1 (de) | 2004-12-13 | 2011-07-15 | Canji Inc | Zellinien zur produktion von replikationsdefektem adenovirus |
US20070249043A1 (en) * | 2005-12-12 | 2007-10-25 | Mayall Timothy P | Adenoviral expression vectors |
US20070231301A1 (en) * | 2006-03-31 | 2007-10-04 | Warren Stephen L | Parenteral low dose type 1 interferons for bladder cancer |
US8877206B2 (en) | 2007-03-22 | 2014-11-04 | Pds Biotechnology Corporation | Stimulation of an immune response by cationic lipids |
WO2009129227A1 (en) | 2008-04-17 | 2009-10-22 | Pds Biotechnology Corporation | Stimulation of an immune response by enantiomers of cationic lipids |
TWI672149B (zh) | 2012-09-21 | 2019-09-21 | 美商Pds生技公司 | 改良之疫苗組成物及使用方法 |
WO2017083820A1 (en) | 2015-11-13 | 2017-05-18 | Pds Biotechnology Corporation | Lipids as synthetic vectors to enhance antigen processing and presentation ex-vivo in dendritic cell therapy |
KR102129195B1 (ko) * | 2016-02-15 | 2020-07-01 | 에프케이디 테라피즈 리미티드, | 향상된 인터페론 치료 |
EP3442588A4 (en) * | 2016-04-14 | 2020-02-19 | Trizell Ltd. | VIRAL VECTOR STABILIZATION |
US20190321321A1 (en) * | 2017-12-05 | 2019-10-24 | Pds Biotechnology Coporation | Methods and compositions comprising cationic lipids for stimulating type 1 interferon genes |
CN111363726A (zh) * | 2018-12-26 | 2020-07-03 | 上海元宋生物技术有限公司 | 表达干扰素的溶瘤病毒及其应用 |
US20200222477A1 (en) * | 2019-01-10 | 2020-07-16 | Trizell Ltd. | Method to Curtail the Progression of Non-Muscle Invasive Bladder Cancer To Muscle-Invasive Cancer |
EP4121115A1 (en) | 2020-03-19 | 2023-01-25 | Trizell Ltd. | Temperature-responsive virus storage system |
JP2023519709A (ja) * | 2020-03-30 | 2023-05-12 | トライゼル リミテッド | がんを治療するための組成物及び方法 |
Family Cites Families (30)
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US4235871A (en) | 1978-02-24 | 1980-11-25 | Papahadjopoulos Demetrios P | Method of encapsulating biologically active materials in lipid vesicles |
US4394448A (en) | 1978-02-24 | 1983-07-19 | Szoka Jr Francis C | Method of inserting DNA into living cells |
US4501728A (en) | 1983-01-06 | 1985-02-26 | Technology Unlimited, Inc. | Masking of liposomes from RES recognition |
US5019369A (en) | 1984-10-22 | 1991-05-28 | Vestar, Inc. | Method of targeting tumors in humans |
US5618711A (en) * | 1986-08-22 | 1997-04-08 | Hoffmann-La Roche Inc. | Recombinant expression vectors and purification methods for Thermus thermophilus DNA polymerase |
US4837028A (en) | 1986-12-24 | 1989-06-06 | Liposome Technology, Inc. | Liposomes with enhanced circulation time |
EP0331635A3 (en) | 1988-02-29 | 1990-02-28 | The Board of Regents of the University of Texas System | Preparations for treating bladder cancer |
US6207454B1 (en) * | 1989-10-16 | 2001-03-27 | Amgen Inc. | Method for enhancing the effciency of gene transfer with stem cell factor (SCF) polypeptide |
US5120316A (en) * | 1990-09-28 | 1992-06-09 | Akzo N.V. | Urethral catheter and catheterization process |
US5602023A (en) * | 1992-03-24 | 1997-02-11 | Csatary; Laszlo K. | Pharmaceutical product containing live, stabilized virus for the therapy of viral and malignant diseases and process for preparing the same |
US5631236A (en) * | 1993-08-26 | 1997-05-20 | Baylor College Of Medicine | Gene therapy for solid tumors, using a DNA sequence encoding HSV-Tk or VZV-Tk |
US5804566A (en) * | 1993-08-26 | 1998-09-08 | The Regents Of The University Of California | Methods and devices for immunizing a host through administration of naked polynucleotides with encode allergenic peptides |
US6210939B1 (en) | 1993-10-25 | 2001-04-03 | Canji, Inc. | Recombinant adenoviral vector and methods of use |
US5552309A (en) * | 1994-09-30 | 1996-09-03 | Indiana University Foundation | Use of polyols for improving the introduction of genetic material into cells |
WO1996012406A1 (en) * | 1994-10-19 | 1996-05-02 | Genetic Therapy, Inc. | Gene therapy involving concurrent and repeated administration of adenoviruses and immunosuppressive agents |
US5650096A (en) | 1994-12-09 | 1997-07-22 | Genzyme Corporation | Cationic amphiphiles for intracellular delivery of therapeutic molecules |
WO1997005209A1 (en) | 1995-07-28 | 1997-02-13 | Kohne David E | Method for enhancing chemiluminescence |
US7002027B1 (en) * | 1996-01-08 | 2006-02-21 | Canji, Inc. | Compositions and methods for therapeutic use |
US5789244A (en) * | 1996-01-08 | 1998-08-04 | Canji, Inc. | Compositions and methods for the treatment of cancer using recombinant viral vector delivery systems |
US6392069B2 (en) | 1996-01-08 | 2002-05-21 | Canji, Inc. | Compositions for enhancing delivery of nucleic acids to cells |
US20040014709A1 (en) * | 1996-01-08 | 2004-01-22 | Canji, Inc. | Methods and compositions for interferon therapy |
BR9712362A (pt) * | 1996-10-18 | 1999-08-31 | Canji Inc | Métodos e composições para distribuição e expressão de ácidos nucléicos de alfa-interferon |
US6210969B1 (en) * | 1999-04-28 | 2001-04-03 | Coulter International Corp. | Composition and method for differentiation of basophil and eosinophil subpopulations of leukocytes in blood |
US20040002474A1 (en) * | 1999-10-07 | 2004-01-01 | Maxygen Inc. | IFN-alpha homologues |
PT1456377T (pt) * | 2001-12-20 | 2019-09-10 | Merck Sharp & Dohme | Composições de syn3 e processos |
WO2003073998A2 (en) * | 2002-03-02 | 2003-09-12 | Board Of Regents, The University Of Texas System | Local production and/or delivery of anti-cancer agents by stromal cell precursors |
WO2004108088A2 (en) * | 2003-06-04 | 2004-12-16 | Canji, Inc. | Methods and compositions for interferon therapy |
CN101396555A (zh) * | 2003-06-04 | 2009-04-01 | 坎基股份有限公司 | 用于干扰素治疗的方法和组合物 |
JP4801594B2 (ja) | 2003-12-10 | 2011-10-26 | カンジ,インコーポレイテッド | インターフェロン耐性腫瘍の処置のための方法および組成物 |
US20070249043A1 (en) * | 2005-12-12 | 2007-10-25 | Mayall Timothy P | Adenoviral expression vectors |
-
2004
- 2004-12-10 JP JP2006543988A patent/JP4801594B2/ja not_active Expired - Fee Related
- 2004-12-10 EP EP10180208A patent/EP2301584A1/en not_active Withdrawn
- 2004-12-10 BR BRPI0417451-8A patent/BRPI0417451A/pt not_active IP Right Cessation
- 2004-12-10 CN CN2004800371241A patent/CN1893981B/zh active Active
- 2004-12-10 SG SG201007186-8A patent/SG166117A1/en unknown
- 2004-12-10 AT AT04813611T patent/ATE502654T1/de not_active IP Right Cessation
- 2004-12-10 WO PCT/US2004/041307 patent/WO2005058368A1/en active Application Filing
- 2004-12-10 KR KR1020067010818A patent/KR101163248B1/ko active IP Right Grant
- 2004-12-10 AU AU2004298991A patent/AU2004298991A1/en not_active Abandoned
- 2004-12-10 EP EP04813611A patent/EP1691844B1/en active Active
- 2004-12-10 DE DE602004031973T patent/DE602004031973D1/de active Active
- 2004-12-10 SG SG200704175-9A patent/SG133594A1/en unknown
- 2004-12-10 US US11/009,689 patent/US7691822B2/en active Active
- 2004-12-10 CA CA2548100A patent/CA2548100C/en not_active Expired - Fee Related
- 2004-12-10 ES ES04813611T patent/ES2363912T3/es active Active
-
2006
- 2006-05-22 IL IL175820A patent/IL175820A0/en unknown
- 2006-05-24 NO NO20062385A patent/NO20062385L/no not_active Application Discontinuation
- 2006-06-06 ZA ZA200604640A patent/ZA200604640B/en unknown
-
2007
- 2007-02-16 HK HK07101922.4A patent/HK1095525A1/xx unknown
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2010
- 2010-02-16 US US12/706,625 patent/US9439977B2/en active Active
-
2011
- 2011-05-02 JP JP2011103283A patent/JP2011148834A/ja active Pending
-
2015
- 2015-10-27 US US14/924,136 patent/US20160045618A1/en not_active Abandoned
-
2018
- 2018-12-10 US US16/214,180 patent/US20190374654A1/en not_active Abandoned
-
2020
- 2020-01-10 US US16/739,245 patent/US20200164091A1/en not_active Abandoned
-
2021
- 2021-04-29 US US17/244,835 patent/US20210322572A1/en active Pending
-
2023
- 2023-09-15 US US18/368,641 patent/US20240000968A1/en active Pending
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Legal Events
Date | Code | Title | Description |
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B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE AS 6A E 7A ANUIDADES. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2158 DE 15/05/2012. |