ATE344031T1 - Thrombopoietin-mimetika - Google Patents
Thrombopoietin-mimetikaInfo
- Publication number
- ATE344031T1 ATE344031T1 AT00984123T AT00984123T ATE344031T1 AT E344031 T1 ATE344031 T1 AT E344031T1 AT 00984123 T AT00984123 T AT 00984123T AT 00984123 T AT00984123 T AT 00984123T AT E344031 T1 ATE344031 T1 AT E344031T1
- Authority
- AT
- Austria
- Prior art keywords
- mammal
- invented
- thrombopoietin mimetics
- mimetics
- thrombopoietin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/10—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16913099P | 1999-12-06 | 1999-12-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE344031T1 true ATE344031T1 (de) | 2006-11-15 |
Family
ID=22614367
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00984123T ATE344031T1 (de) | 1999-12-06 | 2000-12-06 | Thrombopoietin-mimetika |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP1244446B1 (de) |
| JP (1) | JP2003515560A (de) |
| AT (1) | ATE344031T1 (de) |
| AU (1) | AU2079901A (de) |
| DE (1) | DE60031714T2 (de) |
| ES (1) | ES2275567T3 (de) |
| WO (1) | WO2001039773A1 (de) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004016264A1 (ja) | 2002-08-14 | 2004-02-26 | Nissan Chemical Industries, Ltd. | トロンボポエチンレセプター活性化剤ならびにそれらの製造方法 |
| TWI324593B (en) | 2002-10-09 | 2010-05-11 | Nissan Chemical Ind Ltd | Pyrazolone compounds and thrombopoietin receptor activator |
| DK1569912T3 (en) | 2002-12-03 | 2015-06-29 | Pharmacyclics Inc | 2- (2-hydroxybiphenyl-3-yl) -1h-benzoimidazole-5-carboxamidine derivatives as factor VIIa inhibitors. |
| EP1581527A4 (de) * | 2002-12-13 | 2006-11-22 | Smithkline Beecham Corp | Thrombopoietin-mimetika |
| US8030336B2 (en) * | 2002-12-13 | 2011-10-04 | Ym Biosciences Australia Pty Ltd | Nicotinamide-based kinase inhibitors |
| TW200418791A (en) * | 2003-01-23 | 2004-10-01 | Bristol Myers Squibb Co | Pharmaceutical compositions for inhibiting proteasome |
| WO2005016862A1 (en) * | 2003-08-14 | 2005-02-24 | Asahi Kasei Pharma Corporation | Substituted arylalkanoic acid derivative and use thereof |
| US8729117B2 (en) | 2004-06-02 | 2014-05-20 | Pharmacyclics, Inc. | Factor VIIa inhibitor |
| TWI351954B (en) | 2004-12-08 | 2011-11-11 | Nissan Chemical Ind Ltd | Heterocyclic compounds and thrombopoietin receptor |
| TWI399368B (zh) | 2004-12-14 | 2013-06-21 | Nissan Chemical Ind Ltd | Amide compounds and thrombopoietin receptor activators |
| MX2008000462A (es) | 2005-07-14 | 2008-03-10 | Irm Llc | Compuestos heterotetraciclicos como mimeticos de tpo. |
| EP1904472A1 (de) | 2005-07-15 | 2008-04-02 | Nissan Chemical Industries, Ltd. | Thiophen-verbindungen und thrombopoietin-rezeptor-aktivatoren |
| US7960425B2 (en) | 2005-07-20 | 2011-06-14 | Nissan Chemical Industries, Ltd. | Pyrazole compounds and thrombopoietin receptor activators |
| CA2618634A1 (en) * | 2005-08-15 | 2007-02-22 | Irm Llc | Compounds and compositions as tpo mimetics |
| EP1947101A4 (de) | 2005-11-07 | 2009-09-16 | Nissan Chemical Ind Ltd | Hydrazidverbindung und thrombopoietinrezeptoraktivator |
| EP2025671A4 (de) | 2006-06-07 | 2011-04-06 | Nissan Chemical Ind Ltd | Stickstoffhaltige heterocyclische verbindung und thrombopoietinrezeptoraktivator |
| CA2656810C (en) | 2006-07-11 | 2012-03-13 | Daewoong Pharmaceutical Co., Ltd. | Biaryl benzoimidazole derivatives and pharmaceutical composition comprising the same |
| CN101720327A (zh) | 2007-04-30 | 2010-06-02 | 雅培制药有限公司 | 二酰甘油o-酰基转移酶1型酶的抑制剂 |
| CN101481352A (zh) | 2008-01-10 | 2009-07-15 | 上海恒瑞医药有限公司 | 双环取代吡唑酮偶氮类衍生物、其制备方法及其在医药上的应用 |
| PE20100362A1 (es) | 2008-10-30 | 2010-05-27 | Irm Llc | Derivados de purina que expanden las celulas madre hematopoyeticas |
| CN101921232A (zh) | 2009-06-11 | 2010-12-22 | 上海恒瑞医药有限公司 | 双环取代吡唑酮偶氮类衍生物的盐,其制备方法及其在医药上的应用 |
| WO2012102937A2 (en) | 2011-01-25 | 2012-08-02 | Irm Llc | Compounds that expand hematopoietic stem cells |
| AU2012347534B2 (en) | 2011-12-08 | 2018-01-25 | Fred Hutchinson Cancer Research Center | Compositions and methods for enhanced generation of hematopoietic stem/progenitor cells |
| BR112014018524B1 (pt) | 2012-01-27 | 2023-03-28 | Universite De Montreal | Derivados de pirimido [4,5-b]indol, seu usos, composição farmaceutica, e método in vivo ou ex vivo para aumen-tar as células estaminais e/ou progenitoras |
| CN111620870B (zh) | 2014-04-22 | 2023-01-03 | 蒙特利尔大学 | 化合物及其在扩增造血干细胞和/或造血祖细胞中的应用 |
| SG11201703407UA (en) | 2014-10-31 | 2017-05-30 | Nissan Chemical Ind Ltd | Ligand-binding fiber and cell culture substrate using said fiber |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE193350C (de) * | ||||
| US851444A (en) * | 1905-11-13 | 1907-04-23 | Agfa Ag | Amido-oxy-sulfonic acid of phenylnaphthimidazol and process of making same. |
| US4435417A (en) * | 1981-02-20 | 1984-03-06 | Gruppo Lepetit S.P.A. | Antiinflammatory 3H-naphtho[1,2-d]imidazoles |
| DE4126612A1 (de) * | 1990-08-14 | 1992-02-20 | Ciba Geigy Ag | Reaktivfarbstoffe, deren herstellung und verwendung |
| PT98673B (pt) * | 1990-08-15 | 1999-01-29 | British Bio Technology | Processo para a preparacao de compostos que sao antagonistas do factor de activacao de plaquetas por exemplo derivados de benzimidazole e de seus intermediarios |
-
2000
- 2000-12-06 AU AU20799/01A patent/AU2079901A/en not_active Abandoned
- 2000-12-06 EP EP00984123A patent/EP1244446B1/de not_active Expired - Lifetime
- 2000-12-06 JP JP2001541505A patent/JP2003515560A/ja active Pending
- 2000-12-06 AT AT00984123T patent/ATE344031T1/de not_active IP Right Cessation
- 2000-12-06 WO PCT/US2000/033432 patent/WO2001039773A1/en active IP Right Grant
- 2000-12-06 ES ES00984123T patent/ES2275567T3/es not_active Expired - Lifetime
- 2000-12-06 DE DE60031714T patent/DE60031714T2/de not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE60031714D1 (de) | 2006-12-14 |
| ES2275567T3 (es) | 2007-06-16 |
| AU2079901A (en) | 2001-06-12 |
| WO2001039773A1 (en) | 2001-06-07 |
| EP1244446A4 (de) | 2003-01-08 |
| EP1244446A1 (de) | 2002-10-02 |
| EP1244446B1 (de) | 2006-11-02 |
| DE60031714T2 (de) | 2007-09-06 |
| JP2003515560A (ja) | 2003-05-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |