ATE338749T1 - Derivate von 3-phenyl-n-(2-(4-benzyl)piperidin-1- yl)ethyl) acrylamid mit ccr-3-rezeptor antagonistischer wirkung zur verwendung bei der behandlung von entzündungen und allergischen leiden - Google Patents
Derivate von 3-phenyl-n-(2-(4-benzyl)piperidin-1- yl)ethyl) acrylamid mit ccr-3-rezeptor antagonistischer wirkung zur verwendung bei der behandlung von entzündungen und allergischen leidenInfo
- Publication number
- ATE338749T1 ATE338749T1 AT02767151T AT02767151T ATE338749T1 AT E338749 T1 ATE338749 T1 AT E338749T1 AT 02767151 T AT02767151 T AT 02767151T AT 02767151 T AT02767151 T AT 02767151T AT E338749 T1 ATE338749 T1 AT E338749T1
- Authority
- AT
- Austria
- Prior art keywords
- sup
- phenyl
- ccr
- piperidine
- acrylamide
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
- C07D211/14—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/48—Oxygen atoms attached in position 4 having an acyclic carbon atom attached in position 4
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0114699.2A GB0114699D0 (en) | 2001-06-15 | 2001-06-15 | Organic compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE338749T1 true ATE338749T1 (de) | 2006-09-15 |
Family
ID=9916722
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT02767151T ATE338749T1 (de) | 2001-06-15 | 2002-06-14 | Derivate von 3-phenyl-n-(2-(4-benzyl)piperidin-1- yl)ethyl) acrylamid mit ccr-3-rezeptor antagonistischer wirkung zur verwendung bei der behandlung von entzündungen und allergischen leiden |
Country Status (8)
Country | Link |
---|---|
US (1) | US7259173B2 (de) |
EP (1) | EP1401814B1 (de) |
AT (1) | ATE338749T1 (de) |
DE (1) | DE60214554T2 (de) |
ES (1) | ES2269762T3 (de) |
GB (1) | GB0114699D0 (de) |
PT (1) | PT1401814E (de) |
WO (1) | WO2002102775A1 (de) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10244842B4 (de) | 2002-09-22 | 2006-09-14 | Stiftung Alfred-Wegener-Institut Für Polar- Und Meeresforschung | Für proteinspaltende Enzyme in Form von spezifischen Proteasen kodierende Nukleinsäuresequenzen, zugehörige Polypeptide und Verwendung von allen |
TW202140550A (zh) | 2020-01-29 | 2021-11-01 | 瑞士商諾華公司 | 使用抗tslp抗體治療炎性或阻塞性氣道疾病之方法 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0660160B2 (ja) | 1985-12-13 | 1994-08-10 | テルモ株式会社 | アミド誘導体およびこれを含有する抗アレルギ−剤 |
IL125658A0 (en) | 1997-08-18 | 1999-04-11 | Hoffmann La Roche | Ccr-3 receptor antagonists |
CN1163484C (zh) | 1998-11-17 | 2004-08-25 | 霍夫曼-拉罗奇有限公司 | 4-芳酰基-哌啶-ccr-3受体拮抗剂ⅲ |
ATE386720T1 (de) * | 1998-11-20 | 2008-03-15 | Hoffmann La Roche | Piperidin ccr-3 rezeptor-hemmer |
HUP0202017A3 (en) | 1999-03-26 | 2003-03-28 | Astrazeneca Ab | Novel compounds |
TWI227231B (en) | 2000-07-12 | 2005-02-01 | Novartis Ag | 4-benzoyl-piperidine derivatives for treating conditions mediated by CCR-3 |
-
2001
- 2001-06-15 GB GBGB0114699.2A patent/GB0114699D0/en not_active Ceased
-
2002
- 2002-06-14 AT AT02767151T patent/ATE338749T1/de not_active IP Right Cessation
- 2002-06-14 PT PT02767151T patent/PT1401814E/pt unknown
- 2002-06-14 EP EP02767151A patent/EP1401814B1/de not_active Expired - Lifetime
- 2002-06-14 ES ES02767151T patent/ES2269762T3/es not_active Expired - Lifetime
- 2002-06-14 US US10/478,795 patent/US7259173B2/en not_active Expired - Fee Related
- 2002-06-14 DE DE60214554T patent/DE60214554T2/de not_active Expired - Lifetime
- 2002-06-14 WO PCT/EP2002/006588 patent/WO2002102775A1/en active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
US7259173B2 (en) | 2007-08-21 |
GB0114699D0 (en) | 2001-08-08 |
PT1401814E (pt) | 2006-12-29 |
ES2269762T3 (es) | 2007-04-01 |
US20040180926A1 (en) | 2004-09-16 |
WO2002102775A1 (en) | 2002-12-27 |
DE60214554D1 (de) | 2006-10-19 |
EP1401814A1 (de) | 2004-03-31 |
EP1401814B1 (de) | 2006-09-06 |
DE60214554T2 (de) | 2007-09-27 |
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