ATE338127T1 - Ribonukleaseresistente rna präparation und seine verwendung - Google Patents
Ribonukleaseresistente rna präparation und seine verwendungInfo
- Publication number
- ATE338127T1 ATE338127T1 AT97933547T AT97933547T ATE338127T1 AT E338127 T1 ATE338127 T1 AT E338127T1 AT 97933547 T AT97933547 T AT 97933547T AT 97933547 T AT97933547 T AT 97933547T AT E338127 T1 ATE338127 T1 AT E338127T1
- Authority
- AT
- Austria
- Prior art keywords
- rna preparation
- ribonuclease resistant
- resistant rna
- ribonuclease
- nucleic acids
- Prior art date
Links
- 102000006382 Ribonucleases Human genes 0.000 title abstract 2
- 108010083644 Ribonucleases Proteins 0.000 title abstract 2
- 102000039446 nucleic acids Human genes 0.000 abstract 2
- 108020004707 nucleic acids Proteins 0.000 abstract 2
- 150000007523 nucleic acids Chemical class 0.000 abstract 2
- 102000040650 (ribonucleotides)n+m Human genes 0.000 abstract 1
- 108091032973 (ribonucleotides)n+m Proteins 0.000 abstract 1
- 101710163270 Nuclease Proteins 0.000 abstract 1
Classifications
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- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/88—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microencapsulation, e.g. using amphiphile liposome vesicle
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- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
- C12P19/30—Nucleotides
- C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6851—Quantitative amplification
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
- C12Q1/706—Specific hybridization probes for hepatitis
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- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16061—Methods of inactivation or attenuation
- C12N2740/16062—Methods of inactivation or attenuation by genetic engineering
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- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16211—Human Immunodeficiency Virus, HIV concerning HIV gagpol
- C12N2740/16222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/00022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/00023—Virus like particles [VLP]
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- C12N2770/00011—Details
- C12N2770/00041—Use of virus, viral particle or viral elements as a vector
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- C12N2770/00011—Details
- C12N2770/34011—Potyviridae
- C12N2770/34022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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- C12N2770/00011—Details
- C12N2770/34011—Potyviridae
- C12N2770/34023—Virus like particles [VLP]
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- C12N2770/00011—Details
- C12N2770/34011—Potyviridae
- C12N2770/34041—Use of virus, viral particle or viral elements as a vector
- C12N2770/34042—Use of virus, viral particle or viral elements as a vector virus or viral particle as vehicle, e.g. encapsulating small organic molecule
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- C12N2770/00011—Details
- C12N2770/36011—Togaviridae
- C12N2770/36111—Alphavirus, e.g. Sindbis virus, VEE, EEE, WEE, Semliki
- C12N2770/36123—Virus like particles [VLP]
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- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/36011—Togaviridae
- C12N2770/36111—Alphavirus, e.g. Sindbis virus, VEE, EEE, WEE, Semliki
- C12N2770/36141—Use of virus, viral particle or viral elements as a vector
- C12N2770/36143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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- C12N2795/00—Bacteriophages
- C12N2795/00011—Details
- C12N2795/10011—Details dsDNA Bacteriophages
- C12N2795/10111—Myoviridae
- C12N2795/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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- C12N2795/00—Bacteriophages
- C12N2795/00011—Details
- C12N2795/10011—Details dsDNA Bacteriophages
- C12N2795/10111—Myoviridae
- C12N2795/10141—Use of virus, viral particle or viral elements as a vector
- C12N2795/10142—Use of virus, viral particle or viral elements as a vector virus or viral particle as vehicle, e.g. encapsulating small organic molecule
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- C12N2795/00—Bacteriophages
- C12N2795/00011—Details
- C12N2795/18011—Details ssRNA Bacteriophages positive-sense
- C12N2795/18111—Leviviridae
- C12N2795/18122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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- C12N2795/00—Bacteriophages
- C12N2795/00011—Details
- C12N2795/18011—Details ssRNA Bacteriophages positive-sense
- C12N2795/18111—Leviviridae
- C12N2795/18123—Virus like particles [VLP]
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- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
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- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Virology (AREA)
- Analytical Chemistry (AREA)
- Communicable Diseases (AREA)
- Plant Pathology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Gastroenterology & Hepatology (AREA)
- General Chemical & Material Sciences (AREA)
- Crystallography & Structural Chemistry (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2114596P | 1996-07-03 | 1996-07-03 | |
| US08/675,153 US5677124A (en) | 1996-07-03 | 1996-07-03 | Ribonuclease resistant viral RNA standards |
| US08/881,571 US5939262A (en) | 1996-07-03 | 1997-06-24 | Ribonuclease resistant RNA preparation and utilization |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE338127T1 true ATE338127T1 (de) | 2006-09-15 |
Family
ID=26694321
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97933547T ATE338127T1 (de) | 1996-07-03 | 1997-07-02 | Ribonukleaseresistente rna präparation und seine verwendung |
Country Status (8)
| Country | Link |
|---|---|
| US (5) | US5939262A (enExample) |
| EP (1) | EP0910643B1 (enExample) |
| JP (2) | JP4315471B2 (enExample) |
| AT (1) | ATE338127T1 (enExample) |
| AU (1) | AU729601B2 (enExample) |
| CA (1) | CA2258485C (enExample) |
| DE (1) | DE69736598T2 (enExample) |
| WO (1) | WO1998000547A1 (enExample) |
Families Citing this family (87)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5939262A (en) * | 1996-07-03 | 1999-08-17 | Ambion, Inc. | Ribonuclease resistant RNA preparation and utilization |
| DE19737442C2 (de) * | 1997-08-22 | 1999-06-24 | Olfert Landt Tib Molbiol Synth | Proteinumhüllte Polyribonukleinsäuren, ein Verfahren zu ihrer Herstellung und ihre Verwendung |
| AU9319398A (en) * | 1997-09-19 | 1999-04-05 | Sequitur, Inc. | Sense mrna therapy |
| EP1892299A3 (en) * | 1997-09-19 | 2011-07-20 | Life Technologies Corporation | Sense mRNA therapy |
| US7767422B2 (en) * | 1998-09-22 | 2010-08-03 | Oncomedx, Inc. | Detection of 5T4 RNA in plasma and serum |
| US6777210B1 (en) | 1998-09-24 | 2004-08-17 | Ambion, Inc. | Method and reagents for inactivating ribonucleases RNase A, RNase I and RNase T1 |
| DE19956568A1 (de) * | 1999-01-30 | 2000-08-17 | Roland Kreutzer | Verfahren und Medikament zur Hemmung der Expression eines vorgegebenen Gens |
| KR20000065690A (ko) * | 1999-04-08 | 2000-11-15 | 박종구 | 반응 특이성 및 안정성을 개선시킨 안티센스 올리고 뉴클레오타이드, 안티센스 dna 및 그 제조방법 |
| US7829693B2 (en) * | 1999-11-24 | 2010-11-09 | Alnylam Pharmaceuticals, Inc. | Compositions and methods for inhibiting expression of a target gene |
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-
1997
- 1997-06-24 US US08/881,571 patent/US5939262A/en not_active Expired - Lifetime
- 1997-07-02 EP EP97933547A patent/EP0910643B1/en not_active Expired - Lifetime
- 1997-07-02 CA CA2258485A patent/CA2258485C/en not_active Expired - Lifetime
- 1997-07-02 AT AT97933547T patent/ATE338127T1/de not_active IP Right Cessation
- 1997-07-02 WO PCT/US1997/012551 patent/WO1998000547A1/en not_active Ceased
- 1997-07-02 AU AU36709/97A patent/AU729601B2/en not_active Expired
- 1997-07-02 DE DE69736598T patent/DE69736598T2/de not_active Expired - Lifetime
- 1997-07-02 JP JP50452798A patent/JP4315471B2/ja not_active Expired - Lifetime
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1999
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2000
- 2000-09-19 US US09/665,638 patent/US6399307B1/en not_active Expired - Lifetime
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2002
- 2002-04-10 US US10/120,013 patent/US7033749B2/en not_active Expired - Fee Related
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2005
- 2005-12-21 US US11/316,340 patent/US20060257889A1/en not_active Abandoned
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2009
- 2009-03-09 JP JP2009055769A patent/JP2009131272A/ja not_active Withdrawn
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| US5939262A (en) | 1999-08-17 |
| WO1998000547A1 (en) | 1998-01-08 |
| EP0910643B1 (en) | 2006-08-30 |
| AU729601B2 (en) | 2001-02-08 |
| JP2002514905A (ja) | 2002-05-21 |
| DE69736598D1 (de) | 2006-10-12 |
| US6214982B1 (en) | 2001-04-10 |
| CA2258485A1 (en) | 1998-01-08 |
| US20060257889A1 (en) | 2006-11-16 |
| JP4315471B2 (ja) | 2009-08-19 |
| CA2258485C (en) | 2013-01-29 |
| DE69736598T2 (de) | 2007-08-09 |
| US7033749B2 (en) | 2006-04-25 |
| US20020192689A1 (en) | 2002-12-19 |
| JP2009131272A (ja) | 2009-06-18 |
| EP0910643A1 (en) | 1999-04-28 |
| AU3670997A (en) | 1998-01-21 |
| US6399307B1 (en) | 2002-06-04 |
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