DE69835813D1 - Verfahren zur kultivierung von zellen und zur vermehrung von viren - Google Patents

Verfahren zur kultivierung von zellen und zur vermehrung von viren

Info

Publication number
DE69835813D1
DE69835813D1 DE69835813T DE69835813T DE69835813D1 DE 69835813 D1 DE69835813 D1 DE 69835813D1 DE 69835813 T DE69835813 T DE 69835813T DE 69835813 T DE69835813 T DE 69835813T DE 69835813 D1 DE69835813 D1 DE 69835813D1
Authority
DE
Germany
Prior art keywords
viruses
improving
culturing cells
methods
propagating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69835813T
Other languages
English (en)
Other versions
DE69835813T2 (de
Inventor
G Condon
V Connelly
Andreas Frei
Edward Glowacki
Vijay Yabannavar
Serge Batondolo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme Corp
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of DE69835813D1 publication Critical patent/DE69835813D1/de
Application granted granted Critical
Publication of DE69835813T2 publication Critical patent/DE69835813T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2531/00—Microcarriers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10351—Methods of production or purification of viral material

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Virology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
DE69835813T 1997-01-31 1998-01-28 Verfahren zur kultivierung von zellen und zur vermehrung von viren Expired - Fee Related DE69835813T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US79767797A 1997-01-31 1997-01-31
US79767697A 1997-01-31 1997-01-31
US797677 1997-01-31
US797676 1997-01-31
PCT/US1998/000911 WO1998033886A1 (en) 1997-01-31 1998-01-28 Methods for cultivating cells and propagating viruses

Publications (2)

Publication Number Publication Date
DE69835813D1 true DE69835813D1 (de) 2006-10-19
DE69835813T2 DE69835813T2 (de) 2007-09-13

Family

ID=27121912

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69835813T Expired - Fee Related DE69835813T2 (de) 1997-01-31 1998-01-28 Verfahren zur kultivierung von zellen und zur vermehrung von viren

Country Status (10)

Country Link
EP (2) EP1731598A1 (de)
JP (2) JP2001509675A (de)
AT (1) ATE338814T1 (de)
AU (1) AU6028898A (de)
CA (1) CA2278808C (de)
DE (1) DE69835813T2 (de)
DK (1) DK0981601T3 (de)
ES (1) ES2273404T3 (de)
IL (2) IL131014A0 (de)
WO (1) WO1998033886A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6951752B2 (en) * 2001-12-10 2005-10-04 Bexter Healthcare S.A. Method for large scale production of virus antigen
JP2003219865A (ja) * 2002-01-29 2003-08-05 Japan Tissue Engineering:Kk スフェロイドの作製方法、スフェロイド及びスフェロイド含有組成物
CN1688686A (zh) * 2002-04-08 2005-10-26 米列姆·贝尔罗吉克公司 自动化组织工程系统
EP1718738A2 (de) 2004-02-23 2006-11-08 Crucell Holland B.V. Verfahren zur reinigung von viren
DE102004049290A1 (de) 2004-10-09 2006-04-20 Bayer Healthcare Ag Verfahren zur Herstellung von Virusmaterial
ATE412737T1 (de) 2005-04-11 2008-11-15 Crucell Holland Bv Virusreinigung mit ultrafiltration
JP6303497B2 (ja) * 2013-12-27 2018-04-04 株式会社Ihi 細胞剥離回収装置及び細胞剥離回収方法及び細胞培養システム
JP2016036274A (ja) * 2014-08-06 2016-03-22 株式会社Ihi 細胞剥離方法、細胞剥離装置、及び、細胞培養システム
GB201509193D0 (en) * 2015-05-28 2015-07-15 Ge Healthcare Bio Sciences Ab Method and system for cell cultivation
EP3303549B1 (de) 2015-05-29 2019-10-02 Mesoblast International Sàrl Verfahren und vorrichtung zum trennen von zellen aus mikroträgern
IL264798B2 (en) * 2016-08-21 2023-10-01 Adva Biotechnology Ltd Bioreactor and methods of use
JP6480093B2 (ja) * 2017-02-27 2019-03-06 剛士 田邊 体細胞製造システム
CN108103030B (zh) * 2018-01-08 2021-04-30 兆丰华生物科技(福州)有限公司 一种微载体生物反应器培养猪圆环病毒2型的方法
CA3120129A1 (en) * 2018-11-21 2020-05-28 Western Oncolytics Ltd. Manufacture of virus

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986001531A1 (en) * 1984-08-28 1986-03-13 Massachusetts Institute Of Technology Detachment of anchorage-dependent cells from microcarriers
HRP950097A2 (en) * 1994-03-08 1997-06-30 Merck & Co Inc Hepatitis a virus culture process

Also Published As

Publication number Publication date
EP0981601A1 (de) 2000-03-01
JP2008067720A (ja) 2008-03-27
ES2273404T3 (es) 2007-05-01
IL131014A0 (en) 2001-01-28
IL181695A0 (en) 2007-07-04
WO1998033886A1 (en) 1998-08-06
CA2278808C (en) 2006-04-04
EP1731598A1 (de) 2006-12-13
EP0981601B1 (de) 2006-09-06
JP2001509675A (ja) 2001-07-24
CA2278808A1 (en) 1998-08-06
DE69835813T2 (de) 2007-09-13
DK0981601T3 (da) 2007-01-15
AU6028898A (en) 1998-08-25
ATE338814T1 (de) 2006-09-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee