DE69823372T8 - Verfahren und reagentiensatz zur amplifizierung, sequenzierung und typisierung von hla i genen - Google Patents

Verfahren und reagentiensatz zur amplifizierung, sequenzierung und typisierung von hla i genen Download PDF

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Publication number
DE69823372T8
DE69823372T8 DE69823372T DE69823372T DE69823372T8 DE 69823372 T8 DE69823372 T8 DE 69823372T8 DE 69823372 T DE69823372 T DE 69823372T DE 69823372 T DE69823372 T DE 69823372T DE 69823372 T8 DE69823372 T8 DE 69823372T8
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DE
Germany
Prior art keywords
hla
typing
sequencing
genes
amplification
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE69823372T
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English (en)
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DE69823372T2 (de
DE69823372D1 (de
Inventor
Elizabeth Caroline GAREY
James Leushner
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Siemens Healthcare Diagnostics Inc
Original Assignee
Bayer Healthcare LLC
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Publication of DE69823372D1 publication Critical patent/DE69823372D1/de
Publication of DE69823372T2 publication Critical patent/DE69823372T2/de
Publication of DE69823372T8 publication Critical patent/DE69823372T8/de
Active legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6858—Allele-specific amplification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6881—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/16—Primer sets for multiplex assays
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/81—Packaged device or kit

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DE69823372T 1997-10-10 1998-10-09 Verfahren und reagentiensatz zur amplifizierung, sequenzierung und typisierung von hla i genen Active DE69823372T8 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/948,717 US5910413A (en) 1997-10-10 1997-10-10 Method and kit for amplification, sequencing and typing of classical HLA class I genes
US948717 1997-10-10
PCT/CA1998/000950 WO1999019509A2 (en) 1997-10-10 1998-10-09 Method and kit for amplification, sequencing and typing of classical hla class i genes

Publications (3)

Publication Number Publication Date
DE69823372D1 DE69823372D1 (de) 2004-05-27
DE69823372T2 DE69823372T2 (de) 2005-05-04
DE69823372T8 true DE69823372T8 (de) 2005-11-03

Family

ID=25488180

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69823372T Active DE69823372T8 (de) 1997-10-10 1998-10-09 Verfahren und reagentiensatz zur amplifizierung, sequenzierung und typisierung von hla i genen

Country Status (7)

Country Link
US (1) US5910413A (de)
EP (1) EP1021559B1 (de)
JP (1) JP2001520020A (de)
AU (1) AU9425798A (de)
CA (1) CA2302810A1 (de)
DE (1) DE69823372T8 (de)
WO (1) WO1999019509A2 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0953650A1 (de) 1998-04-20 1999-11-03 Innogenetics N.V. Verfahren für die HLA Typisierung
ES2351686T3 (es) * 1999-04-09 2011-02-09 Innogenetics N.V. Método para la amplificación de alelos hla de clase i.
AU5062500A (en) * 1999-04-26 2000-11-10 Amersham Pharmacia Biotech Ab Primers for identifying typing or classifying nucleic acids
FR2793809B1 (fr) 1999-05-20 2006-07-28 Biomerieux Sa Procede d'analyse de la predisposition genetique d'un patient a au moins une maladie et amplification adaptee a un tel procede
WO2004078999A1 (en) * 2003-03-05 2004-09-16 Genetic Technologies Limited Identification of fetal dna and fetal cell markers in maternal plasma or serum
KR100581002B1 (ko) * 2003-03-25 2006-05-17 바이오코아 주식회사 Ｈｌａ 유전자형 분석을 위한 올리고뉴크레오티드 조성물및 그 검사 방법
JP2005102599A (ja) * 2003-09-30 2005-04-21 Shimadzu Corp Ｈｌａタイピング法
WO2005090605A1 (en) * 2004-03-24 2005-09-29 Biocore Co., Ltd. Oligonucleotide composition for analyzing human leukocyte antigen (hla) genotype and detecting method thereof
WO2007035836A2 (en) * 2005-09-20 2007-03-29 The Board Of Regents Of The University Of Oklahoma Accelerated class i and class ii hla dna sequence-based typing
CA2654729A1 (en) * 2006-06-09 2007-12-13 Conexio 4 Pty Ltd Identification of a nucleic acid molecule
US20100086914A1 (en) * 2008-10-03 2010-04-08 Roche Molecular Systems, Inc. High resolution, high throughput hla genotyping by clonal sequencing
US9012148B2 (en) * 2008-04-16 2015-04-21 Jian Han Method for evaluating and comparing immunorepertoires
US20100261189A1 (en) * 2008-10-03 2010-10-14 Roche Molecular Systems, Inc. System and method for detection of HLA Variants
US9416419B2 (en) 2009-11-16 2016-08-16 Michael E. Hogan Methods for PCR and HLA typing using unpurified samples
US8771951B2 (en) * 2009-11-16 2014-07-08 Genomics Usa, Inc. Methods for PCR and HLA typing using raw blood
WO2015047220A2 (en) * 2013-09-24 2015-04-02 Georgetown University Compositions and methods for single g-level hla typing
CA2937460A1 (en) * 2014-02-18 2015-08-27 Etablissement Francais Du Sang High-resolution hla typing

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5424184A (en) * 1991-05-08 1995-06-13 Regents Of The University Of Minnesota DNA sequence-based HLA class I typing method
EP0540997A1 (de) * 1991-11-05 1993-05-12 F. Hoffmann-La Roche Ag Verfahren und Reagenzien zur Typisierung von HLA-Klass-I-DNS
WO1997023645A1 (en) * 1996-01-04 1997-07-03 Sloan-Kettering Institute For Cancer Research Methods and reagents for typing hla class i genes
CA2213731C (en) * 1996-02-20 2003-09-09 The Perkin-Elmer Corporation Methods and reagents for typing hla class i genes
WO1998026091A2 (en) * 1996-12-12 1998-06-18 Visible Genetics, Inc. Method and kit for hla class i typing
EP0986650A4 (de) * 1997-02-11 2004-07-07 William H Hildebrand Auf klasse-i basierende typisierung von hla-a, -b, -c allelen durch direkte dns sequenzierung
EP1003917A1 (de) * 1997-08-11 2000-05-31 Visible Genetics Inc. Verfahren und kit zur typisierung von hla klass-i dns

Also Published As

Publication number Publication date
AU9425798A (en) 1999-05-03
EP1021559B1 (de) 2004-04-21
CA2302810A1 (en) 1999-04-22
EP1021559A2 (de) 2000-07-26
WO1999019509A3 (en) 1999-06-24
DE69823372T2 (de) 2005-05-04
JP2001520020A (ja) 2001-10-30
US5910413A (en) 1999-06-08
DE69823372D1 (de) 2004-05-27
WO1999019509A2 (en) 1999-04-22

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: BAYER HEALTHCARE LLC (N.D.GES.D. STAATES DELAWARE)

8327 Change in the person/name/address of the patent owner

Owner name: SIEMENS HEALTHCARE DIAGNOSTICS INC. (N.D.GES.D, US

8328 Change in the person/name/address of the agent

Representative=s name: MAIER, D., DIPL.-ING. UNIV., PAT.-ASS., 81739 MUEN