DE69823372D1 - Verfahren und reagentiensatz zur amplifizierung, sequenzierung und typisierung von hla i genen - Google Patents
Verfahren und reagentiensatz zur amplifizierung, sequenzierung und typisierung von hla i genenInfo
- Publication number
- DE69823372D1 DE69823372D1 DE69823372T DE69823372T DE69823372D1 DE 69823372 D1 DE69823372 D1 DE 69823372D1 DE 69823372 T DE69823372 T DE 69823372T DE 69823372 T DE69823372 T DE 69823372T DE 69823372 D1 DE69823372 D1 DE 69823372D1
- Authority
- DE
- Germany
- Prior art keywords
- amplificating
- sequencing
- genes
- reagent set
- typing hla
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6858—Allele-specific amplification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6881—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/16—Primer sets for multiplex assays
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/81—Packaged device or kit
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Cell Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/948,717 US5910413A (en) | 1997-10-10 | 1997-10-10 | Method and kit for amplification, sequencing and typing of classical HLA class I genes |
US948717 | 1997-10-10 | ||
PCT/CA1998/000950 WO1999019509A2 (en) | 1997-10-10 | 1998-10-09 | Method and kit for amplification, sequencing and typing of classical hla class i genes |
Publications (3)
Publication Number | Publication Date |
---|---|
DE69823372D1 true DE69823372D1 (de) | 2004-05-27 |
DE69823372T2 DE69823372T2 (de) | 2005-05-04 |
DE69823372T8 DE69823372T8 (de) | 2005-11-03 |
Family
ID=25488180
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69823372T Active DE69823372T8 (de) | 1997-10-10 | 1998-10-09 | Verfahren und reagentiensatz zur amplifizierung, sequenzierung und typisierung von hla i genen |
Country Status (7)
Country | Link |
---|---|
US (1) | US5910413A (de) |
EP (1) | EP1021559B1 (de) |
JP (1) | JP2001520020A (de) |
AU (1) | AU9425798A (de) |
CA (1) | CA2302810A1 (de) |
DE (1) | DE69823372T8 (de) |
WO (1) | WO1999019509A2 (de) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0953650A1 (de) | 1998-04-20 | 1999-11-03 | Innogenetics N.V. | Verfahren für die HLA Typisierung |
ES2351686T3 (es) * | 1999-04-09 | 2011-02-09 | Innogenetics N.V. | Método para la amplificación de alelos hla de clase i. |
AU5062500A (en) * | 1999-04-26 | 2000-11-10 | Amersham Pharmacia Biotech Ab | Primers for identifying typing or classifying nucleic acids |
FR2793809B1 (fr) | 1999-05-20 | 2006-07-28 | Biomerieux Sa | Procede d'analyse de la predisposition genetique d'un patient a au moins une maladie et amplification adaptee a un tel procede |
WO2004078999A1 (en) * | 2003-03-05 | 2004-09-16 | Genetic Technologies Limited | Identification of fetal dna and fetal cell markers in maternal plasma or serum |
KR100581002B1 (ko) * | 2003-03-25 | 2006-05-17 | 바이오코아 주식회사 | Hla 유전자형 분석을 위한 올리고뉴크레오티드 조성물및 그 검사 방법 |
JP2005102599A (ja) * | 2003-09-30 | 2005-04-21 | Shimadzu Corp | Hlaタイピング法 |
WO2005090605A1 (en) * | 2004-03-24 | 2005-09-29 | Biocore Co., Ltd. | Oligonucleotide composition for analyzing human leukocyte antigen (hla) genotype and detecting method thereof |
WO2007035836A2 (en) * | 2005-09-20 | 2007-03-29 | The Board Of Regents Of The University Of Oklahoma | Accelerated class i and class ii hla dna sequence-based typing |
CA2654729A1 (en) * | 2006-06-09 | 2007-12-13 | Conexio 4 Pty Ltd | Identification of a nucleic acid molecule |
US20100086914A1 (en) * | 2008-10-03 | 2010-04-08 | Roche Molecular Systems, Inc. | High resolution, high throughput hla genotyping by clonal sequencing |
US9012148B2 (en) * | 2008-04-16 | 2015-04-21 | Jian Han | Method for evaluating and comparing immunorepertoires |
US20100261189A1 (en) * | 2008-10-03 | 2010-10-14 | Roche Molecular Systems, Inc. | System and method for detection of HLA Variants |
US9416419B2 (en) | 2009-11-16 | 2016-08-16 | Michael E. Hogan | Methods for PCR and HLA typing using unpurified samples |
US8771951B2 (en) * | 2009-11-16 | 2014-07-08 | Genomics Usa, Inc. | Methods for PCR and HLA typing using raw blood |
WO2015047220A2 (en) * | 2013-09-24 | 2015-04-02 | Georgetown University | Compositions and methods for single g-level hla typing |
CA2937460A1 (en) * | 2014-02-18 | 2015-08-27 | Etablissement Francais Du Sang | High-resolution hla typing |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5424184A (en) * | 1991-05-08 | 1995-06-13 | Regents Of The University Of Minnesota | DNA sequence-based HLA class I typing method |
EP0540997A1 (de) * | 1991-11-05 | 1993-05-12 | F. Hoffmann-La Roche Ag | Verfahren und Reagenzien zur Typisierung von HLA-Klass-I-DNS |
WO1997023645A1 (en) * | 1996-01-04 | 1997-07-03 | Sloan-Kettering Institute For Cancer Research | Methods and reagents for typing hla class i genes |
CA2213731C (en) * | 1996-02-20 | 2003-09-09 | The Perkin-Elmer Corporation | Methods and reagents for typing hla class i genes |
WO1998026091A2 (en) * | 1996-12-12 | 1998-06-18 | Visible Genetics, Inc. | Method and kit for hla class i typing |
EP0986650A4 (de) * | 1997-02-11 | 2004-07-07 | William H Hildebrand | Auf klasse-i basierende typisierung von hla-a, -b, -c allelen durch direkte dns sequenzierung |
EP1003917A1 (de) * | 1997-08-11 | 2000-05-31 | Visible Genetics Inc. | Verfahren und kit zur typisierung von hla klass-i dns |
-
1997
- 1997-10-10 US US08/948,717 patent/US5910413A/en not_active Expired - Lifetime
-
1998
- 1998-10-09 JP JP2000516060A patent/JP2001520020A/ja active Pending
- 1998-10-09 AU AU94257/98A patent/AU9425798A/en not_active Abandoned
- 1998-10-09 EP EP98947253A patent/EP1021559B1/de not_active Expired - Lifetime
- 1998-10-09 WO PCT/CA1998/000950 patent/WO1999019509A2/en active IP Right Grant
- 1998-10-09 DE DE69823372T patent/DE69823372T8/de active Active
- 1998-10-09 CA CA002302810A patent/CA2302810A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
AU9425798A (en) | 1999-05-03 |
EP1021559B1 (de) | 2004-04-21 |
DE69823372T8 (de) | 2005-11-03 |
CA2302810A1 (en) | 1999-04-22 |
EP1021559A2 (de) | 2000-07-26 |
WO1999019509A3 (en) | 1999-06-24 |
DE69823372T2 (de) | 2005-05-04 |
JP2001520020A (ja) | 2001-10-30 |
US5910413A (en) | 1999-06-08 |
WO1999019509A2 (en) | 1999-04-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8327 | Change in the person/name/address of the patent owner |
Owner name: BAYER HEALTHCARE LLC (N.D.GES.D. STAATES DELAWARE) |
|
8327 | Change in the person/name/address of the patent owner |
Owner name: SIEMENS HEALTHCARE DIAGNOSTICS INC. (N.D.GES.D, US |
|
8328 | Change in the person/name/address of the agent |
Representative=s name: MAIER, D., DIPL.-ING. UNIV., PAT.-ASS., 81739 MUEN |