DE69736598T2 - Ribonukleaseresistente rna präparation und seine verwendung - Google Patents
Ribonukleaseresistente rna präparation und seine verwendung Download PDFInfo
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- DE69736598T2 DE69736598T2 DE69736598T DE69736598T DE69736598T2 DE 69736598 T2 DE69736598 T2 DE 69736598T2 DE 69736598 T DE69736598 T DE 69736598T DE 69736598 T DE69736598 T DE 69736598T DE 69736598 T2 DE69736598 T2 DE 69736598T2
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- rna
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- bacteriophage
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Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
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| US2114596P | 1996-07-03 | 1996-07-03 | |
| US675153 | 1996-07-03 | ||
| US08/675,153 US5677124A (en) | 1996-07-03 | 1996-07-03 | Ribonuclease resistant viral RNA standards |
| US21145P | 1996-07-03 | ||
| US08/881,571 US5939262A (en) | 1996-07-03 | 1997-06-24 | Ribonuclease resistant RNA preparation and utilization |
| US881571 | 1997-06-24 | ||
| PCT/US1997/012551 WO1998000547A1 (en) | 1996-07-03 | 1997-07-02 | Ribonuclease resistant rna preparation and utilization |
Publications (2)
| Publication Number | Publication Date |
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| DE69736598D1 DE69736598D1 (de) | 2006-10-12 |
| DE69736598T2 true DE69736598T2 (de) | 2007-08-09 |
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| DE69736598T Expired - Lifetime DE69736598T2 (de) | 1996-07-03 | 1997-07-02 | Ribonukleaseresistente rna präparation und seine verwendung |
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| US (5) | US5939262A (enExample) |
| EP (1) | EP0910643B1 (enExample) |
| JP (2) | JP4315471B2 (enExample) |
| AT (1) | ATE338127T1 (enExample) |
| AU (1) | AU729601B2 (enExample) |
| CA (1) | CA2258485C (enExample) |
| DE (1) | DE69736598T2 (enExample) |
| WO (1) | WO1998000547A1 (enExample) |
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| US5939262A (en) * | 1996-07-03 | 1999-08-17 | Ambion, Inc. | Ribonuclease resistant RNA preparation and utilization |
| DE19737442C2 (de) * | 1997-08-22 | 1999-06-24 | Olfert Landt Tib Molbiol Synth | Proteinumhüllte Polyribonukleinsäuren, ein Verfahren zu ihrer Herstellung und ihre Verwendung |
| EP1892299A3 (en) * | 1997-09-19 | 2011-07-20 | Life Technologies Corporation | Sense mRNA therapy |
| JP2002508299A (ja) * | 1997-09-19 | 2002-03-19 | セクイター, インク. | センスmRNA治療 |
| US7767422B2 (en) * | 1998-09-22 | 2010-08-03 | Oncomedx, Inc. | Detection of 5T4 RNA in plasma and serum |
| US6777210B1 (en) * | 1998-09-24 | 2004-08-17 | Ambion, Inc. | Method and reagents for inactivating ribonucleases RNase A, RNase I and RNase T1 |
| DE19956568A1 (de) * | 1999-01-30 | 2000-08-17 | Roland Kreutzer | Verfahren und Medikament zur Hemmung der Expression eines vorgegebenen Gens |
| KR20000065690A (ko) * | 1999-04-08 | 2000-11-15 | 박종구 | 반응 특이성 및 안정성을 개선시킨 안티센스 올리고 뉴클레오타이드, 안티센스 dna 및 그 제조방법 |
| US7829693B2 (en) * | 1999-11-24 | 2010-11-09 | Alnylam Pharmaceuticals, Inc. | Compositions and methods for inhibiting expression of a target gene |
| CA2402452A1 (en) * | 2000-03-31 | 2001-10-11 | Cambridge Antibody Technology Limited | Improvements to ribosome display |
| ATE498020T1 (de) * | 2000-08-28 | 2011-02-15 | Oncomedx Inc | 5t4 rna in plasma und serum als marker für neoplastische erkrankungen |
| GB0021303D0 (en) * | 2000-08-30 | 2000-10-18 | Medinnova Sf | Use |
| RU2189396C2 (ru) * | 2000-10-27 | 2002-09-20 | Федеральное государственное учреждение науки и здравоохранения Нижегородский научно-исследовательский институт эпидемиологии и микробиологии им. акад. И.Н.Блохиной | Способ обнаружения и дифференциации рнк энтеровирусов |
| US8546143B2 (en) | 2001-01-09 | 2013-10-01 | Alnylam Pharmaceuticals, Inc. | Compositions and methods for inhibiting expression of a target gene |
| US20020172972A1 (en) * | 2001-05-15 | 2002-11-21 | President And Fellows Of Harvard College | Use of a selectively inactivatable enzyme to digest contaminating nucleic acid |
| JP2005514012A (ja) * | 2001-12-06 | 2005-05-19 | ザ アーロン ダイアモンド エイズ リサーチ センター | キメラバクテリオファージ標準を使用する高感度ゲノムアッセイ |
| EP2290098A1 (en) | 2002-01-28 | 2011-03-02 | Ambion, Inc. | Preparing crude biological extracts using protease, suitable for preparing cDNA |
| US20060009409A1 (en) | 2002-02-01 | 2006-01-12 | Woolf Tod M | Double-stranded oligonucleotides |
| CA2474910A1 (en) | 2002-02-01 | 2003-08-07 | Sequitur, Inc. | Oligonucleotide compositions with enhanced efficiency |
| JP2006507800A (ja) * | 2002-06-07 | 2006-03-09 | ラージ・スケール・バイオロジー・コーポレイション | 可撓性ワクチンアセンブリおよびワクチン送達プラットフォーム |
| US7482116B2 (en) | 2002-06-07 | 2009-01-27 | Dna Genotek Inc. | Compositions and methods for obtaining nucleic acids from sputum |
| WO2004085611A2 (en) * | 2003-03-21 | 2004-10-07 | The Research Foundation Of State University Of New York | Model for mutually exclusive domain folding molecular switch |
| GB2422196B (en) * | 2003-05-20 | 2008-05-07 | Investigen Inc | System for detecting polynucleotides |
| CN100577680C (zh) | 2003-07-03 | 2010-01-06 | 宾夕法尼亚大学理事会 | 对Syk激酶表达的抑制 |
| EP1694692B1 (en) * | 2003-12-16 | 2010-04-28 | QIAGEN North American Holdings, Inc. | Formulations and methods for denaturing proteins |
| CA2561741C (en) | 2004-04-05 | 2016-09-27 | Alnylam Pharmaceuticals, Inc. | Processes and reagents for oligonucleotide synthesis and purification |
| US7626014B2 (en) | 2004-04-27 | 2009-12-01 | Alnylam Pharmaceuticals | Single-stranded and double-stranded oligonucleotides comprising a 2-arylpropyl moiety |
| AU2005323437B2 (en) * | 2004-04-30 | 2011-10-06 | Alnylam Pharmaceuticals, Inc. | Oligonucleotides comprising a C5-modified pyrimidine |
| CA2572151A1 (en) * | 2004-06-30 | 2006-08-24 | Alnylam Pharmaceuticals, Inc. | Oligonucleotides comprising a non-phosphate backbone linkage |
| WO2006093526A2 (en) | 2004-07-21 | 2006-09-08 | Alnylam Pharmaceuticals, Inc. | Oligonucleotides comprising a modified or non-natural nucleobase |
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| US20060257889A1 (en) | 2006-11-16 |
| ATE338127T1 (de) | 2006-09-15 |
| JP4315471B2 (ja) | 2009-08-19 |
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| JP2009131272A (ja) | 2009-06-18 |
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| AU729601B2 (en) | 2001-02-08 |
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| CA2258485C (en) | 2013-01-29 |
| US5939262A (en) | 1999-08-17 |
| US7033749B2 (en) | 2006-04-25 |
| US6214982B1 (en) | 2001-04-10 |
| JP2002514905A (ja) | 2002-05-21 |
| DE69736598D1 (de) | 2006-10-12 |
| US20020192689A1 (en) | 2002-12-19 |
| CA2258485A1 (en) | 1998-01-08 |
| EP0910643B1 (en) | 2006-08-30 |
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