ATE331727T1 - Magnetisch aktivierte zellsortierung zur herstellung von proteinen - Google Patents

Magnetisch aktivierte zellsortierung zur herstellung von proteinen

Info

Publication number
ATE331727T1
ATE331727T1 AT97911009T AT97911009T ATE331727T1 AT E331727 T1 ATE331727 T1 AT E331727T1 AT 97911009 T AT97911009 T AT 97911009T AT 97911009 T AT97911009 T AT 97911009T AT E331727 T1 ATE331727 T1 AT E331727T1
Authority
AT
Austria
Prior art keywords
protein
cells
virus
antigen
expressing
Prior art date
Application number
AT97911009T
Other languages
English (en)
Inventor
Donald L Siegel
Original Assignee
Univ Pennsylvania
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Pennsylvania filed Critical Univ Pennsylvania
Application granted granted Critical
Publication of ATE331727T1 publication Critical patent/ATE331727T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/02—Libraries contained in or displayed by microorganisms, e.g. bacteria or animal cells; Libraries contained in or displayed by vectors, e.g. plasmids; Libraries containing only microorganisms or vectors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/34—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood group antigens
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
    • C12N15/1006—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers
    • C12N15/1013—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers by using magnetic beads
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1037—Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT97911009T 1996-10-11 1997-10-10 Magnetisch aktivierte zellsortierung zur herstellung von proteinen ATE331727T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2855096P 1996-10-11 1996-10-11
US08/884,045 US5876925A (en) 1996-10-11 1997-06-27 Magnetically activated cell sorting for production of proteins

Publications (1)

Publication Number Publication Date
ATE331727T1 true ATE331727T1 (de) 2006-07-15

Family

ID=26703823

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97911009T ATE331727T1 (de) 1996-10-11 1997-10-10 Magnetisch aktivierte zellsortierung zur herstellung von proteinen

Country Status (9)

Country Link
US (1) US5876925A (de)
EP (1) EP0935604B1 (de)
JP (1) JP4101298B2 (de)
AT (1) ATE331727T1 (de)
AU (1) AU722978B2 (de)
CA (1) CA2268397C (de)
DE (1) DE69736239T2 (de)
ES (1) ES2267134T3 (de)
WO (1) WO1998016541A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6255455B1 (en) * 1996-10-11 2001-07-03 The Trustees Of The University Of Pennsylvania Rh(D)-binding proteins and magnetically activated cell sorting method for production thereof
DE10129815A1 (de) * 2001-06-24 2003-01-09 Profos Ag Verfahren zur Aufreinigung von Bakterienzellen und Zellbestandteilen
EP1487969A4 (de) * 2001-12-07 2008-07-09 Dyax Corp Verfahren und vorrichtung zum waschen von magnetisch reagierenden teilchen
WO2004027028A2 (en) * 2002-09-18 2004-04-01 The Trustees Of The University Of Pennsylvania Compositions, methods and kits for detection of an antigen on a cell and in a biological mixture
DE102004033811A1 (de) * 2004-07-12 2006-02-02 Salama, Abdulgabar, Prof. Dr. Verfahren zum einfachen und schnellen Nachweis von Zellen und Biomolekülen mit Hilfe paramagnetischer Partikel
WO2006007853A2 (en) 2004-07-20 2006-01-26 Symphogen A/S A procedure for structural characterization of a recombinant polyclonal protein or a polyclonal cell line
BRPI0513706A (pt) * 2004-07-20 2008-05-13 Symphogen As anticorpo policlonal recombinante anti-rhesus d e métodos de produção
US9658224B2 (en) 2005-11-29 2017-05-23 The Trustees Of The University Of Pennsylvania Phage particle diagnostic reagents
EP2015798A2 (de) * 2006-05-05 2009-01-21 Erysave AB Trennungsverfahren
EP2537589A1 (de) 2011-06-21 2012-12-26 Siemens Aktiengesellschaft Verfahren zum Trennen eines ersten Stoffes aus einem fließfähigen Primärstoffstrom, Vorrichtung zum Trennen eines ersten Stoffes aus einem fließfähigen Primärstoffstrom und Steuer- und/oder Regeleinrichtung
MY191368A (en) * 2013-06-28 2022-06-20 X Body Inc Target antigen discovery, phenotypic screens and use thereof for identification of target cell specific target epitopes
EP3798305A4 (de) * 2018-04-27 2022-02-09 Aimed Bio Inc. Magnetbasiertes biopanningverfahren durch anbringen eines magnetischen kügelchens an einer zelle

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5338689A (en) * 1987-08-24 1994-08-16 Stiftung Fur Diagnostische Forschung Method and card for detecting antigens and/or antibodies
US5663143A (en) * 1988-09-02 1997-09-02 Dyax Corp. Engineered human-derived kunitz domains that inhibit human neutrophil elastase
US5498538A (en) * 1990-02-15 1996-03-12 The University Of North Carolina At Chapel Hill Totally synthetic affinity reagents
DK1471142T3 (da) * 1991-04-10 2009-03-09 Scripps Research Inst Heterodimere receptor-biblioteker under anvendelse af fagemider
US5665558A (en) * 1994-05-17 1997-09-09 Gamma Biologicals, Inc. Method and apparatus useful for detecting bloodgroup antigens and antibodies

Also Published As

Publication number Publication date
CA2268397C (en) 2008-02-12
DE69736239T2 (de) 2007-05-10
AU4824797A (en) 1998-05-11
WO1998016541A1 (en) 1998-04-23
US5876925A (en) 1999-03-02
EP0935604B1 (de) 2006-06-28
AU722978B2 (en) 2000-08-17
JP4101298B2 (ja) 2008-06-18
ES2267134T3 (es) 2007-03-01
JP2002503085A (ja) 2002-01-29
CA2268397A1 (en) 1998-04-23
DE69736239D1 (de) 2006-08-10
EP0935604A1 (de) 1999-08-18
EP0935604A4 (de) 2004-10-20

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