DE69736239D1 - Magnetisch aktivierte zellsortierung zur herstellung von proteinen - Google Patents

Magnetisch aktivierte zellsortierung zur herstellung von proteinen

Info

Publication number
DE69736239D1
DE69736239D1 DE69736239T DE69736239T DE69736239D1 DE 69736239 D1 DE69736239 D1 DE 69736239D1 DE 69736239 T DE69736239 T DE 69736239T DE 69736239 T DE69736239 T DE 69736239T DE 69736239 D1 DE69736239 D1 DE 69736239D1
Authority
DE
Germany
Prior art keywords
protein
cells
virus
antigen
proteins
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69736239T
Other languages
English (en)
Other versions
DE69736239T2 (de
Inventor
L Siegel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Pennsylvania Penn
Original Assignee
University of Pennsylvania Penn
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Pennsylvania Penn filed Critical University of Pennsylvania Penn
Application granted granted Critical
Publication of DE69736239D1 publication Critical patent/DE69736239D1/de
Publication of DE69736239T2 publication Critical patent/DE69736239T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/02—Libraries contained in or displayed by microorganisms, e.g. bacteria or animal cells; Libraries contained in or displayed by vectors, e.g. plasmids; Libraries containing only microorganisms or vectors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/34—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood group antigens
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
    • C12N15/1006—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers
    • C12N15/1013—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers by using magnetic beads
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1037—Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Virology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE69736239T 1996-10-11 1997-10-10 Magnetisch aktivierte zellsortierung zur herstellung von proteinen Expired - Lifetime DE69736239T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US2855096P 1996-10-11 1996-10-11
US28550P 1996-10-11
US08/884,045 US5876925A (en) 1996-10-11 1997-06-27 Magnetically activated cell sorting for production of proteins
US884045 1997-06-27
PCT/US1997/018808 WO1998016541A1 (en) 1996-10-11 1997-10-10 Magnetically activated cell sorting for production of proteins

Publications (2)

Publication Number Publication Date
DE69736239D1 true DE69736239D1 (de) 2006-08-10
DE69736239T2 DE69736239T2 (de) 2007-05-10

Family

ID=26703823

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69736239T Expired - Lifetime DE69736239T2 (de) 1996-10-11 1997-10-10 Magnetisch aktivierte zellsortierung zur herstellung von proteinen

Country Status (9)

Country Link
US (1) US5876925A (de)
EP (1) EP0935604B1 (de)
JP (1) JP4101298B2 (de)
AT (1) ATE331727T1 (de)
AU (1) AU722978B2 (de)
CA (1) CA2268397C (de)
DE (1) DE69736239T2 (de)
ES (1) ES2267134T3 (de)
WO (1) WO1998016541A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6255455B1 (en) * 1996-10-11 2001-07-03 The Trustees Of The University Of Pennsylvania Rh(D)-binding proteins and magnetically activated cell sorting method for production thereof
DE10129815A1 (de) * 2001-06-24 2003-01-09 Profos Ag Verfahren zur Aufreinigung von Bakterienzellen und Zellbestandteilen
WO2003049530A2 (en) * 2001-12-07 2003-06-19 Dyax Corporation Method and apparatus for washing magnetically responsive particles
MXPA05002934A (es) * 2002-09-18 2006-02-24 Univ Pennsylvania Composiciones, metodos y kits para deteccion de un antigeno en una celula y en una mezcla biologica.
DE102004033811A1 (de) * 2004-07-12 2006-02-02 Salama, Abdulgabar, Prof. Dr. Verfahren zum einfachen und schnellen Nachweis von Zellen und Biomolekülen mit Hilfe paramagnetischer Partikel
EP1771483A1 (de) * 2004-07-20 2007-04-11 Symphogen A/S Rekombinanter polyklonaler anti-rhesus-d-antikörper und herstellungsverfahren
WO2006007853A2 (en) * 2004-07-20 2006-01-26 Symphogen A/S A procedure for structural characterization of a recombinant polyclonal protein or a polyclonal cell line
EP1963494B1 (de) 2005-11-29 2014-10-08 The Trustees of The University of Pennsylvania Diagnostische phagenpartikelreagentien
US20100006501A1 (en) * 2006-05-05 2010-01-14 Erysave Ab Method for separation
EP2537589A1 (de) 2011-06-21 2012-12-26 Siemens Aktiengesellschaft Verfahren zum Trennen eines ersten Stoffes aus einem fließfähigen Primärstoffstrom, Vorrichtung zum Trennen eines ersten Stoffes aus einem fließfähigen Primärstoffstrom und Steuer- und/oder Regeleinrichtung
EP3739336B1 (de) 2013-06-28 2022-05-11 X-Body, Inc. Zielantigenerkennung, phänotypische masken und verwendung davon zur identifikation zielzellspezifischer zielepitope
WO2019209073A1 (ko) * 2018-04-27 2019-10-31 사회복지법인 삼성생명공익재단 세포의 자성 비드 부착을 통한 자성 기반 바이오 패닝 방법

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5338689A (en) * 1987-08-24 1994-08-16 Stiftung Fur Diagnostische Forschung Method and card for detecting antigens and/or antibodies
US5663143A (en) * 1988-09-02 1997-09-02 Dyax Corp. Engineered human-derived kunitz domains that inhibit human neutrophil elastase
US5498538A (en) * 1990-02-15 1996-03-12 The University Of North Carolina At Chapel Hill Totally synthetic affinity reagents
WO1992018619A1 (en) * 1991-04-10 1992-10-29 The Scripps Research Institute Heterodimeric receptor libraries using phagemids
US5665558A (en) * 1994-05-17 1997-09-09 Gamma Biologicals, Inc. Method and apparatus useful for detecting bloodgroup antigens and antibodies

Also Published As

Publication number Publication date
AU4824797A (en) 1998-05-11
AU722978B2 (en) 2000-08-17
JP2002503085A (ja) 2002-01-29
US5876925A (en) 1999-03-02
ES2267134T3 (es) 2007-03-01
DE69736239T2 (de) 2007-05-10
CA2268397A1 (en) 1998-04-23
JP4101298B2 (ja) 2008-06-18
EP0935604B1 (de) 2006-06-28
EP0935604A1 (de) 1999-08-18
ATE331727T1 (de) 2006-07-15
EP0935604A4 (de) 2004-10-20
CA2268397C (en) 2008-02-12
WO1998016541A1 (en) 1998-04-23

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