EE05691B1 - Ekspressioonivektorid ja nende rakendused - Google Patents

Ekspressioonivektorid ja nende rakendused

Info

Publication number
EE05691B1
EE05691B1 EEP200300483A EEP200300483A EE05691B1 EE 05691 B1 EE05691 B1 EE 05691B1 EE P200300483 A EEP200300483 A EE P200300483A EE P200300483 A EEP200300483 A EE P200300483A EE 05691 B1 EE05691 B1 EE 05691B1
Authority
EE
Estonia
Prior art keywords
vectors
relates
dna sequence
nuclear
binding
Prior art date
Application number
EEP200300483A
Other languages
English (en)
Inventor
Krohn Kai
Blazevic Vesna
T�htinen Marja
Ustav Mart
Toots Urve
M�nnik Andres
Ranki Annamari
Ustav Ene
Original Assignee
Fit Biotech Oyj Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FI20010922A external-priority patent/FI116851B/fi
Application filed by Fit Biotech Oyj Plc filed Critical Fit Biotech Oyj Plc
Publication of EE200300483A publication Critical patent/EE200300483A/et
Publication of EE05691B1 publication Critical patent/EE05691B1/et

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53DNA (RNA) vaccination
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2800/00Nucleic acids vectors
    • C12N2800/10Plasmid DNA
    • C12N2800/108Plasmid DNA episomal vectors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00Vector systems having a special element relevant for transcription
    • C12N2830/42Vector systems having a special element relevant for transcription being an intron or intervening sequence for splicing and/or stability of RNA
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2840/00Vectors comprising a special translation-regulating system
    • C12N2840/20Vectors comprising a special translation-regulating system translation of more than one cistron
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2840/00Vectors comprising a special translation-regulating system
    • C12N2840/20Vectors comprising a special translation-regulating system translation of more than one cistron
    • C12N2840/203Vectors comprising a special translation-regulating system translation of more than one cistron having an IRES

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
EEP200300483A 2001-05-03 2002-05-03 Ekspressioonivektorid ja nende rakendused EE05691B1 (et)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FI20010922A FI116851B (fi) 2001-05-03 2001-05-03 Ilmentämisvektori, sen käyttöjä ja menetelmä sen valmistamiseksi sekä sitä sisältäviä tuotteita
US10/138,098 US7498314B2 (en) 2001-05-03 2002-05-03 Expression vectors and uses thereof
PCT/FI2002/000379 WO2002090558A1 (en) 2001-05-03 2002-05-03 Novel expression vectors and uses thereof

Publications (2)

Publication Number Publication Date
EE200300483A EE200300483A (et) 2004-04-15
EE05691B1 true EE05691B1 (et) 2013-12-16

Family

ID=26161168

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200300483A EE05691B1 (et) 2001-05-03 2002-05-03 Ekspressioonivektorid ja nende rakendused

Country Status (23)

Country Link
EP (1) EP1390516B1 (et)
JP (1) JP5016779B2 (et)
CN (1) CN100430482C (et)
AP (1) AP2368A (et)
AT (1) ATE426035T1 (et)
AU (1) AU2002253198B2 (et)
BR (1) BRPI0209416A8 (et)
CA (1) CA2446260C (et)
CZ (1) CZ301691B6 (et)
DE (1) DE60231613D1 (et)
DK (1) DK1390516T3 (et)
EA (1) EA009388B1 (et)
EE (1) EE05691B1 (et)
ES (1) ES2324095T3 (et)
HK (1) HK1063486A1 (et)
HU (1) HU227667B1 (et)
IL (2) IL158730A0 (et)
MX (1) MXPA03009978A (et)
NZ (1) NZ529327A (et)
PL (1) PL206097B1 (et)
SI (1) SI1390516T1 (et)
SK (1) SK287471B6 (et)
WO (1) WO2002090558A1 (et)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003292280A1 (en) * 2002-12-20 2004-07-14 Strom & Gulliksson Ip Ab Vectors lacking an origin of replication functioning in mammalian cells and expressing growth factors
FI116068B (fi) 2003-09-15 2005-09-15 Fit Biotech Oyj Plc Uusi selektiojärjestelmä, siinä käyttökelpoinen vektori, bakteerisolukantoja sekä menetelmä solujen valikoimiseksi
WO2005117997A1 (en) * 2004-06-01 2005-12-15 The Ohio State University Ligands having metal binding ability and targeting properties
EP2047861B1 (en) * 2007-10-12 2019-07-31 Institut Pasteur Lentiviral gene transfer vectors suitable for iterative administration and their medicinal applications
CN102083462B (zh) 2007-08-03 2015-02-18 巴斯德研究院 慢病毒基因转移载体及其医学应用
ES2646320T3 (es) * 2009-03-27 2017-12-13 Eidgenössische Technische Hochschule Zürich Salmonella enterica que presenta un N-glicano de C. Jejuni o derivados del mismo
JP6607784B2 (ja) * 2012-12-06 2019-11-20 ピーアイエヌ ファーマ インコーポレイテッド 免疫抑制性Tat誘導体ポリペプチドを用いた炎症、自己免疫及び神経変性疾患の治療
CN107344962B (zh) * 2016-05-04 2021-03-02 中国科学院微生物研究所 阻遏蛋白、调控元件组和基因表达调控系统及其构建方法
WO2018185110A1 (en) 2017-04-03 2018-10-11 Fit Biotech Oy Novel expression vectors and uses thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4987071A (en) 1986-12-03 1991-01-22 University Patents, Inc. RNA ribozyme polymerases, dephosphorylases, restriction endoribonucleases and methods
JP2000516472A (ja) * 1996-08-16 2000-12-12 メディカル リサーチ カウンシル 組織特異的遺伝子発現を与える自己複製型エピソーム性発現ベクター

Also Published As

Publication number Publication date
HU227667B1 (en) 2011-11-28
CZ301691B6 (cs) 2010-05-26
IL158730A (en) 2010-06-16
WO2002090558A1 (en) 2002-11-14
HUP0304053A3 (en) 2004-10-28
SK287471B6 (sk) 2010-11-08
AU2002253198B2 (en) 2007-08-16
MXPA03009978A (es) 2005-03-07
HUP0304053A2 (hu) 2004-03-29
EP1390516A1 (en) 2004-02-25
CN100430482C (zh) 2008-11-05
SI1390516T1 (sl) 2009-08-31
JP2004533247A (ja) 2004-11-04
AP2003002914A0 (en) 2003-12-31
PL206097B1 (pl) 2010-06-30
EP1390516B1 (en) 2009-03-18
IL158730A0 (en) 2004-05-12
HK1063486A1 (en) 2004-12-31
JP5016779B2 (ja) 2012-09-05
AP2368A (en) 2012-02-27
WO2002090558A9 (en) 2003-02-06
ATE426035T1 (de) 2009-04-15
PL367126A1 (en) 2005-02-21
EE200300483A (et) 2004-04-15
NZ529327A (en) 2006-01-27
DK1390516T3 (da) 2009-07-13
EA009388B1 (ru) 2007-12-28
CZ20033201A3 (en) 2004-05-12
BRPI0209416A2 (pt) 2004-03-30
EA200301207A1 (ru) 2004-08-26
BRPI0209416A8 (pt) 2018-05-08
ES2324095T3 (es) 2009-07-30
CA2446260A1 (en) 2002-11-14
SK14692003A3 (sk) 2004-07-07
CA2446260C (en) 2011-06-14
DE60231613D1 (de) 2009-04-30
CN1529758A (zh) 2004-09-15

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