ATE322281T1 - Nanopartikelzusammensetzungen enthaltend amorphes cyclosporin und deren herstellungsverfahren und verwendungsverfahren - Google Patents
Nanopartikelzusammensetzungen enthaltend amorphes cyclosporin und deren herstellungsverfahren und verwendungsverfahrenInfo
- Publication number
- ATE322281T1 ATE322281T1 AT00959965T AT00959965T ATE322281T1 AT E322281 T1 ATE322281 T1 AT E322281T1 AT 00959965 T AT00959965 T AT 00959965T AT 00959965 T AT00959965 T AT 00959965T AT E322281 T1 ATE322281 T1 AT E322281T1
- Authority
- AT
- Austria
- Prior art keywords
- amorphic
- cyclosporin
- production
- cyclosporine
- compositions containing
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 7
- PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical compound CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 title abstract 5
- 108010036949 Cyclosporine Proteins 0.000 title abstract 5
- 229960001265 ciclosporin Drugs 0.000 title abstract 5
- 229930182912 cyclosporin Natural products 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 2
- 229930105110 Cyclosporin A Natural products 0.000 title 1
- 239000002105 nanoparticle Substances 0.000 title 1
- 238000009472 formulation Methods 0.000 abstract 3
- 239000002245 particle Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Transplantation (AREA)
- Tropical Medicine & Parasitology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/392,557 US6656504B1 (en) | 1999-09-09 | 1999-09-09 | Nanoparticulate compositions comprising amorphous cyclosporine and methods of making and using such compositions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE322281T1 true ATE322281T1 (de) | 2006-04-15 |
Family
ID=23551058
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00959965T ATE322281T1 (de) | 1999-09-09 | 2000-09-07 | Nanopartikelzusammensetzungen enthaltend amorphes cyclosporin und deren herstellungsverfahren und verwendungsverfahren |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6656504B1 (de) |
| EP (1) | EP1210104B1 (de) |
| JP (2) | JP2003508492A (de) |
| AT (1) | ATE322281T1 (de) |
| AU (1) | AU7119500A (de) |
| CA (1) | CA2384670C (de) |
| DE (1) | DE60027171T2 (de) |
| WO (1) | WO2001017546A1 (de) |
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-
1999
- 1999-09-09 US US09/392,557 patent/US6656504B1/en not_active Expired - Fee Related
-
2000
- 2000-09-07 AU AU71195/00A patent/AU7119500A/en not_active Abandoned
- 2000-09-07 JP JP2001521335A patent/JP2003508492A/ja active Pending
- 2000-09-07 CA CA2384670A patent/CA2384670C/en not_active Expired - Fee Related
- 2000-09-07 WO PCT/US2000/024505 patent/WO2001017546A1/en not_active Ceased
- 2000-09-07 EP EP00959965A patent/EP1210104B1/de not_active Expired - Lifetime
- 2000-09-07 DE DE60027171T patent/DE60027171T2/de not_active Expired - Lifetime
- 2000-09-07 AT AT00959965T patent/ATE322281T1/de not_active IP Right Cessation
-
2010
- 2010-08-24 JP JP2010186933A patent/JP2011006450A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| WO2001017546A1 (en) | 2001-03-15 |
| CA2384670C (en) | 2011-01-04 |
| EP1210104B1 (de) | 2006-04-05 |
| DE60027171D1 (de) | 2006-05-18 |
| JP2011006450A (ja) | 2011-01-13 |
| CA2384670A1 (en) | 2001-03-15 |
| DE60027171T2 (de) | 2007-01-04 |
| EP1210104A1 (de) | 2002-06-05 |
| AU7119500A (en) | 2001-04-10 |
| US6656504B1 (en) | 2003-12-02 |
| JP2003508492A (ja) | 2003-03-04 |
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| Date | Code | Title | Description |
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| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |