ATE320794T1 - Aerosolprodukte von steroidlösung mit verbesserter chemischer stabilität - Google Patents

Aerosolprodukte von steroidlösung mit verbesserter chemischer stabilität

Info

Publication number
ATE320794T1
ATE320794T1 AT00941435T AT00941435T ATE320794T1 AT E320794 T1 ATE320794 T1 AT E320794T1 AT 00941435 T AT00941435 T AT 00941435T AT 00941435 T AT00941435 T AT 00941435T AT E320794 T1 ATE320794 T1 AT E320794T1
Authority
AT
Austria
Prior art keywords
chemical stability
improved chemical
aerosol products
steroid solution
solution aerosol
Prior art date
Application number
AT00941435T
Other languages
English (en)
Inventor
Zheng Z Wu
Nayna Govind
Peter R Johnson
Original Assignee
3M Innovative Properties Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22489103&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE320794(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 3M Innovative Properties Co filed Critical 3M Innovative Properties Co
Application granted granted Critical
Publication of ATE320794T1 publication Critical patent/ATE320794T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A61K9/124—Aerosols; Foams characterised by the propellant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D83/00—Containers or packages with special means for dispensing contents
    • B65D83/14—Containers for dispensing liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant
    • B65D83/38—Details of the container body
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D83/00—Containers or packages with special means for dispensing contents
    • B65D83/14—Containers for dispensing liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant
    • B65D83/44—Valves specially adapted for the discharge of contents; Regulating devices
    • B65D83/52—Metering valves; Metering devices

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Mechanical Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Otolaryngology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
AT00941435T 1999-06-18 2000-06-15 Aerosolprodukte von steroidlösung mit verbesserter chemischer stabilität ATE320794T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US13996199P 1999-06-18 1999-06-18

Publications (1)

Publication Number Publication Date
ATE320794T1 true ATE320794T1 (de) 2006-04-15

Family

ID=22489103

Family Applications (2)

Application Number Title Priority Date Filing Date
AT06005429T ATE523190T1 (de) 1999-06-18 2000-06-15 Teroidlösung aerosolformulierung mit verbesserter chemischer stabilität
AT00941435T ATE320794T1 (de) 1999-06-18 2000-06-15 Aerosolprodukte von steroidlösung mit verbesserter chemischer stabilität

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT06005429T ATE523190T1 (de) 1999-06-18 2000-06-15 Teroidlösung aerosolformulierung mit verbesserter chemischer stabilität

Country Status (8)

Country Link
US (4) US6315985B1 (de)
EP (2) EP1693053B1 (de)
JP (1) JP4777560B2 (de)
AT (2) ATE523190T1 (de)
AU (1) AU777505B2 (de)
CA (1) CA2371931A1 (de)
DE (1) DE60026840T2 (de)
WO (1) WO2000078286A1 (de)

Families Citing this family (76)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20010031244A1 (en) * 1997-06-13 2001-10-18 Chiesi Farmaceutici S.P.A. Pharmaceutical aerosol composition
DZ2947A1 (fr) * 1998-11-25 2004-03-15 Chiesi Farma Spa Inhalateur à compteur de dose sous pression.
US6315985B1 (en) * 1999-06-18 2001-11-13 3M Innovative Properties Company C-17/21 OH 20-ketosteroid solution aerosol products with enhanced chemical stability
IT1313553B1 (it) 1999-07-23 2002-09-09 Chiesi Farma Spa Formulazioni ottimizzate costituite da soluzioni di steroidi dasomministrare per inalazione.
GB2354007B (en) * 1999-09-11 2003-10-22 Glaxo Group Ltd Pharmaceutical formulation of fluticasone propionate
WO2001047493A1 (en) * 1999-12-24 2001-07-05 Glaxo Group Limited Pharmaceutical aerosol formulation of salmeterol and fluticasone propionate
IT1317846B1 (it) 2000-02-22 2003-07-15 Chiesi Farma Spa Formulazioni contenenti un farmaco anticolinergico per il trattamentodella broncopneumopatia cronica ostruttiva.
IT1318514B1 (it) * 2000-05-12 2003-08-27 Chiesi Farma Spa Formulazioni contenenti un farmaco glucocorticosteroide per iltrattamento di patologie broncopolmonari.
UA73986C2 (uk) * 2000-05-22 2005-10-17 К'Єзі Фармачеутічі С.П.А. АЕРОЗОЛЬНА КОМПОЗИЦІЯ, ЩО МІСТИТЬ <font face="Symbol">b</font>2-АДРЕНЕРГІЧНИЙ АГОНІСТ ТРИВАЛОЇ ДІЇ, ДОЗУЮЧИЙ ІНГАЛЯТОР ПІД ТИСКОМ ТА СПОСІБ ЙОГО ЗАПОВНЕННЯ
TW523409B (en) * 2000-09-15 2003-03-11 Baxter Int Container for inhalation anesthetic
GB0025092D0 (en) * 2000-10-13 2000-11-29 Glaxo Group Ltd Medicament dispenser
EP1324797A2 (de) * 2000-10-13 2003-07-09 Glaxo Group Limited Spender für medikament
US20020085978A1 (en) * 2000-11-10 2002-07-04 Mina Buenafe Degradation-resistant glucocorticosteroid formulations
DE10062564A1 (de) * 2000-12-15 2002-06-20 Linde Ag Schutzgas und Verfahren zum Lichtbogenschweißen
GB0106046D0 (en) 2001-03-12 2001-05-02 Glaxo Group Ltd Canister
EP1241113A1 (de) 2001-03-12 2002-09-18 CHIESI FARMACEUTICI S.p.A. Inhalator mit Mitteln um chemische Stabilität der darin enthaltenen medizinischen Aerosollösung zu verbessern
EP1273292B1 (de) * 2001-07-02 2004-05-26 CHIESI FARMACEUTICI S.p.A. Optimierte Tobramycin-Formulierung zur Aerosolbildung
GB0122725D0 (en) * 2001-09-21 2001-11-14 Glaxo Group Ltd Drug dispensing components
EP1458354A1 (de) * 2001-12-21 2004-09-22 3M Innovative Properties Company Ionenpaarkomplexe enthaltende medizinische aerosolzusammensetzung
PT3494995T (pt) * 2002-03-01 2020-03-30 Chiesi Farm Spa Formulação superfina de formoterol
US7344707B2 (en) * 2002-05-15 2008-03-18 The Procter & Gamble Company Low combustion aerosol products in plastic packages having a reduced fire hazard classification that subsequently reduces storage costs
US20030215400A1 (en) * 2002-05-15 2003-11-20 The Procter & Gamble Company Pressurized package made of a polyamide resin and containing dimethyl ether
JP3691459B2 (ja) * 2002-06-14 2005-09-07 久光メディカル株式会社 粉末状吸入剤組成物
DE602004027638D1 (de) * 2003-08-04 2010-07-22 Alexza Pharmaceuticals Inc Substrate für eine medikamentenverabreichungsvorrichtung und verfahren zur bereitung
AU2004266658A1 (en) 2003-08-12 2005-03-03 3M Innovative Properties Company Hydroxylamine substituted imidazo-containing compounds
BRPI0413998A (pt) 2003-08-27 2006-11-07 3M Innovative Properties Co imidazoquinolinas arilóxi e arilalquilenóxi substituìdas
US20050054665A1 (en) 2003-09-05 2005-03-10 3M Innovative Properties Company Treatment for CD5+ B cell lymphoma
BRPI0414856A (pt) 2003-10-03 2006-11-21 3M Innovative Properties Co imidazoquinolinas alcóxi-substituìdas
US7544697B2 (en) 2003-10-03 2009-06-09 Coley Pharmaceutical Group, Inc. Pyrazolopyridines and analogs thereof
AR041873A1 (es) 2003-10-30 2005-06-01 Pablo Cassara Srl Lab Una formulacion farmaceutica en aerosol adecuada para la inhalacion oral o nasal que contienen glucocorticoides en solucion estable al almacenamiento; un metodo para estabilzar formulaciones y uso de un agente estabilizante
WO2005048933A2 (en) 2003-11-14 2005-06-02 3M Innovative Properties Company Oxime substituted imidazo ring compounds
CA2545825A1 (en) 2003-11-14 2005-06-02 3M Innovative Properties Company Hydroxylamine substituted imidazo ring compounds
CA2547020C (en) 2003-11-25 2014-03-25 3M Innovative Properties Company 1h-imidazo[4,5-c]pyridine-4-amine derivatives as immune response modifier
US20050121025A1 (en) 2003-12-04 2005-06-09 Gamard Stephan C.F. Portable gas operating inhaler
WO2005066170A1 (en) 2003-12-29 2005-07-21 3M Innovative Properties Company Arylalkenyl and arylalkynyl substituted imidazoquinolines
AU2004312508A1 (en) 2003-12-30 2005-07-21 3M Innovative Properties Company Imidazoquinolinyl, imidazopyridinyl, and imidazonaphthyridinyl sulfonamides
EP1595531A1 (de) 2004-05-13 2005-11-16 CHIESI FARMACEUTICI S.p.A. Stabile Arzneimittellösung für Druckdosierinhalatoren
TW200612932A (en) 2004-03-24 2006-05-01 3M Innovative Properties Co Amide substituted imidazopyridines, imidazoquinolines, and imidazonaphthyridines
WO2005123080A2 (en) 2004-06-15 2005-12-29 3M Innovative Properties Company Nitrogen-containing heterocyclyl substituted imidazoquinolines and imidazonaphthyridines
US7915281B2 (en) 2004-06-18 2011-03-29 3M Innovative Properties Company Isoxazole, dihydroisoxazole, and oxadiazole substituted imidazo ring compounds and method
WO2006009826A1 (en) 2004-06-18 2006-01-26 3M Innovative Properties Company Aryloxy and arylalkyleneoxy substituted thiazoloquinolines and thiazolonaphthyridines
US7897609B2 (en) 2004-06-18 2011-03-01 3M Innovative Properties Company Aryl substituted imidazonaphthyridines
AU2005322898B2 (en) 2004-12-30 2011-11-24 3M Innovative Properties Company Chiral fused (1,2)imidazo(4,5-c) ring compounds
US8034938B2 (en) 2004-12-30 2011-10-11 3M Innovative Properties Company Substituted chiral fused [1,2]imidazo[4,5-c] ring compounds
US9248127B2 (en) 2005-02-04 2016-02-02 3M Innovative Properties Company Aqueous gel formulations containing immune response modifiers
US7968563B2 (en) 2005-02-11 2011-06-28 3M Innovative Properties Company Oxime and hydroxylamine substituted imidazo[4,5-c] ring compounds and methods
AU2006218177B2 (en) * 2005-02-25 2012-04-12 Chiesi Farmaceutici S.P.A. Pharmaceutical aerosol formulations for pressurized metered dose inhalers comprising a sequestering agent
CA2602683A1 (en) 2005-04-01 2006-10-12 Coley Pharmaceutical Group, Inc. Pyrazolopyridine-1,4-diamines and analogs thereof
WO2006107851A1 (en) 2005-04-01 2006-10-12 Coley Pharmaceutical Group, Inc. 1-substituted pyrazolo (3,4-c) ring compounds as modulators of cytokine biosynthesis for the treatment of viral infections and neoplastic diseases
US8277780B2 (en) * 2005-05-27 2012-10-02 Taro Pharmaceutical North America, Inc. Stable liquid desoximethasone compositions with reduced oxidized impurity
WO2007112312A2 (en) * 2006-03-24 2007-10-04 3M Innovative Properties Company Medicinal formulation container with a treated metal surface
US20070231396A1 (en) * 2006-03-29 2007-10-04 Ray Charles D Medication spray formulation
US20070286814A1 (en) * 2006-06-12 2007-12-13 Medispray Laboratories Pvt. Ltd. Stable aerosol pharmaceutical formulations
GB0613761D0 (en) * 2006-07-11 2006-08-23 Norton Healthcare Ltd A pharmaceutical formulation and method for the preparation thereof
WO2008008432A2 (en) 2006-07-12 2008-01-17 Coley Pharmaceutical Group, Inc. Substituted chiral fused( 1,2) imidazo (4,5-c) ring compounds and methods
NZ577284A (en) * 2006-11-20 2012-04-27 Cipla Ltd An aerosol device
EP2121088B1 (de) 2007-03-09 2016-07-13 Alexza Pharmaceuticals, Inc. Erhitzungseinheit zur verwendung in einer arzneimittelabgabevorrichtung
EA201000677A1 (ru) * 2007-11-07 2010-12-30 Астразенека Аб Сухие порошкообразные композиции, содержащие производные аскорбиновой кислоты
US8227027B2 (en) * 2007-12-07 2012-07-24 Presspart Gmbh & Co. Kg Method for applying a polymer coating to an internal surface of a container
US20090208424A1 (en) * 2008-02-19 2009-08-20 Todd Maibach Compositions and methods for delivery of solution to the skin
US9278048B2 (en) * 2009-05-06 2016-03-08 Baxter International, Inc. Pharmaceutical product and method of use
EP3020393B1 (de) 2009-12-16 2020-10-07 3M Innovative Properties Company Formulierungen und verfahren zur steuerung der mdi-partikelgrössenfreisetzung
EP2926855B1 (de) * 2010-10-12 2018-12-05 Ivax Pharmaceuticals Ireland Nasensprayvorrichtung
US20120204871A1 (en) * 2011-02-10 2012-08-16 Julio Cesar Vega Stable, non-corrosive formulations for pressurized metered dose inhalers
DE102014112595A1 (de) * 2014-09-02 2016-03-03 Reinhard Caliebe Dose für ein medizinisches, pharmazeutisches oder kosmetisches Fluid
MX2020007997A (es) 2018-02-02 2020-12-03 Alexza Pharmaceuticals Inc Dispositivo electrico de aerosol de condensacion.
CN111939143A (zh) * 2019-05-16 2020-11-17 鲁南制药集团股份有限公司 一种布地奈德溶液型气雾剂及其制备方法
US12214346B2 (en) 2021-10-13 2025-02-04 Satio, Inc. Dermal patch with a diagnostic test strip
US11964121B2 (en) 2021-10-13 2024-04-23 Satio, Inc. Mono dose dermal patch for pharmaceutical delivery
US12053284B2 (en) 2021-11-08 2024-08-06 Satio, Inc. Dermal patch for collecting a physiological sample
US12048543B2 (en) 2021-11-08 2024-07-30 Satio, Inc. Dermal patch for collecting a physiological sample with removable vial
US12023156B2 (en) 2021-10-13 2024-07-02 Satio, Inc. Dermal patch for collecting a physiological sample
US11877848B2 (en) 2021-11-08 2024-01-23 Satio, Inc. Dermal patch for collecting a physiological sample
US11452474B1 (en) 2021-04-14 2022-09-27 Satio, Inc. Dual lever dermal patch system
US12178979B2 (en) 2021-10-13 2024-12-31 Satio, Inc. Dermal patch for delivering a pharmaceutical
US20250197609A1 (en) 2023-12-13 2025-06-19 Blue Evolution, Inc. Ecofriendly, biodegradable biological polysaccharide composition for packaging materials

Family Cites Families (62)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US577433A (en) * 1897-02-23 Door-alarm
BE555319A (de) * 1956-03-21 1900-01-01
US3361306A (en) * 1966-03-31 1968-01-02 Merck & Co Inc Aerosol unit dispensing uniform amounts of a medically active ingredient
IT1034011B (it) * 1969-06-26 1979-09-10 Vister Vismara Terapeutici S P Processo per la prapratzione di 17 monoesteri di 17 a 21 diossisteroidi per idrolisi die corpispondenti 17 21 ortoesteri ciclici a ph control lato
US3622053A (en) * 1969-12-10 1971-11-23 Schering Corp Aerosol inhaler with flip-up nozzle
US3923484A (en) * 1974-01-11 1975-12-02 Corning Glass Works Flame method of producing glass
US4185100A (en) * 1976-05-13 1980-01-22 Johnson & Johnson Topical anti-inflammatory drug therapy
US4499108A (en) * 1983-06-08 1985-02-12 Schering Corporation Stable pleasant-tasting albuterol sulfate pharmaceutical formulations
GB8334494D0 (en) * 1983-12-24 1984-02-01 Tanabe Seiyaku Co Carbostyril derivatives
IT1196142B (it) * 1984-06-11 1988-11-10 Sicor Spa Procedimento per la preparazione di 16,17-acetali di derivati pregnanici e nuovi composti ottenuti
US5192528A (en) * 1985-05-22 1993-03-09 Liposome Technology, Inc. Corticosteroid inhalation treatment method
GB2216794B (en) 1988-03-22 1991-11-20 Fisons Plc Pharmaceuticals compositions
US5776434A (en) 1988-12-06 1998-07-07 Riker Laboratories, Inc. Medicinal aerosol formulations
US5225183A (en) * 1988-12-06 1993-07-06 Riker Laboratories, Inc. Medicinal aerosol formulations
MX9203481A (es) 1990-10-18 1992-07-01 Minnesota Mining & Mfg Formulaciones.
US6006745A (en) * 1990-12-21 1999-12-28 Minnesota Mining And Manufacturing Company Device for delivering an aerosol
US5435297A (en) * 1991-08-29 1995-07-25 Christoph Klein Medical device for inhaling metered aerosols
DE4230876A1 (de) * 1992-03-17 1993-09-23 Asta Medica Ag Druckgaspackungen unter verwendung von polyoxyethylen-glyceryl-oleaten
ES2129117T3 (es) * 1992-12-09 1999-06-01 Boehringer Ingelheim Pharma Formulaciones en disolucion en forma de aerosol medicinales estabilizadas.
SE9203743D0 (sv) * 1992-12-11 1992-12-11 Astra Ab Efficient use
US6596260B1 (en) 1993-08-27 2003-07-22 Novartis Corporation Aerosol container and a method for storage and administration of a predetermined amount of a pharmaceutically active aerosol
WO1995017195A1 (en) * 1993-12-20 1995-06-29 Minnesota Mining And Manufacturing Company Flunisolide aerosol formulations
US5653961A (en) * 1995-03-31 1997-08-05 Minnesota Mining And Manufacturing Company Butixocort aerosol formulations in hydrofluorocarbon propellant
MX9707864A (es) 1995-04-14 1997-11-29 Glaxo Wellcome Inc Inhalador de dosis medida por salmeterol.
AP960A (en) * 1995-04-14 2001-04-20 Glaxo Wellcome Inc Metered dose inhaler for fluticasone propionate.
PT820279E (pt) 1995-04-14 2002-11-29 Smithkline Beecham Corp Inalador de doses calibradas para albuterol
JP3573213B2 (ja) 1995-04-14 2004-10-06 グラクソ、ウェルカム、インコーポレーテッド ベクロメタゾンジプロピオネート用計量投与用吸入器
JPH11507359A (ja) 1995-06-07 1999-06-29 ローヌ−プーラン ローラー ファーマシューティカルズ インコーポレイテッド 安定化ステロイド組成物
US5776573A (en) 1996-04-16 1998-07-07 Cd Magic, Inc. Compact disc revitalizer formulations and revitalizer
US5743251A (en) 1996-05-15 1998-04-28 Philip Morris Incorporated Aerosol and a method and apparatus for generating an aerosol
GB9620187D0 (en) 1996-09-27 1996-11-13 Minnesota Mining & Mfg Medicinal aerosol formulations
US6039932A (en) * 1996-09-27 2000-03-21 3M Innovative Properties Company Medicinal inhalation aerosol formulations containing budesonide
US6413496B1 (en) * 1996-12-04 2002-07-02 Biogland Ireland (R&D) Limited Pharmaceutical compositions and devices for their administration
NZ336049A (en) 1996-12-04 2000-09-29 Bioglan Ireland R & D Ltd Aersol device for administering pharmaceutical active agents in a solution of propellant, carrier and valve means for delivering this to the exterior of the container
US6126919A (en) * 1997-02-07 2000-10-03 3M Innovative Properties Company Biocompatible compounds for pharmaceutical drug delivery systems
US5891420A (en) * 1997-04-21 1999-04-06 Aeropharm Technology Limited Environmentally safe triancinolone acetonide aerosol formulations for oral inhalation
US5891419A (en) * 1997-04-21 1999-04-06 Aeropharm Technology Limited Environmentally safe flunisolide aerosol formulations for oral inhalation
US6120752A (en) 1997-05-21 2000-09-19 3M Innovative Properties Company Medicinal aerosol products containing formulations of ciclesonide and related steroids
US20010031244A1 (en) * 1997-06-13 2001-10-18 Chiesi Farmaceutici S.P.A. Pharmaceutical aerosol composition
NZ504021A (en) * 1997-10-17 2003-04-29 Systemic Pulmonary Delivery Lt Method and apparatus for delivering aerosolized medication having air discharged through air tube directly into plume of aerosolized medication
GB9805938D0 (en) 1998-03-19 1998-05-13 Glaxo Group Ltd Valve for aerosol container
US6045784A (en) * 1998-05-07 2000-04-04 The Procter & Gamble Company Aerosol package compositions containing fluorinated hydrocarbon propellants
US6451285B2 (en) * 1998-06-19 2002-09-17 Baker Norton Pharmaceuticals, Inc. Suspension aerosol formulations containing formoterol fumarate and a fluoroalkane propellant
US6241969B1 (en) * 1998-06-26 2001-06-05 Elan Corporation Plc Aqueous compositions containing corticosteroids for nasal and pulmonary delivery
DE19847969A1 (de) * 1998-10-17 2000-04-20 Boehringer Ingelheim Pharma Lagerfähig flüssige Formulierung mit Formoterol
DK1131059T3 (da) * 1998-11-13 2003-06-30 Jago Res Ag Tørpulver til inhalation
DZ2947A1 (fr) * 1998-11-25 2004-03-15 Chiesi Farma Spa Inhalateur à compteur de dose sous pression.
IT1303788B1 (it) * 1998-11-25 2001-02-23 Chiesi Farma Spa Formulazioni di aerosol medicinali.
US6261539B1 (en) * 1998-12-10 2001-07-17 Akwete Adjei Medicinal aerosol formulation
US6290930B1 (en) * 1998-12-18 2001-09-18 Baker Norton Pharmaceuticals, Inc. Pharmaceutical solution aerosol formulations containing fluoroalkanes and budesonide
US6004537A (en) * 1998-12-18 1999-12-21 Baker Norton Pharmaceuticals, Inc. Pharmaceutical solution aerosol formulations containing fluoroalkanes, budesonide and formoterol
US6315985B1 (en) 1999-06-18 2001-11-13 3M Innovative Properties Company C-17/21 OH 20-ketosteroid solution aerosol products with enhanced chemical stability
US6322053B1 (en) * 2000-02-08 2001-11-27 Valiant Machine & Tool Inc. Balancing system with a force multiplying device
IT1317846B1 (it) * 2000-02-22 2003-07-15 Chiesi Farma Spa Formulazioni contenenti un farmaco anticolinergico per il trattamentodella broncopneumopatia cronica ostruttiva.
IT1318514B1 (it) * 2000-05-12 2003-08-27 Chiesi Farma Spa Formulazioni contenenti un farmaco glucocorticosteroide per iltrattamento di patologie broncopolmonari.
UA73986C2 (uk) * 2000-05-22 2005-10-17 К'Єзі Фармачеутічі С.П.А. АЕРОЗОЛЬНА КОМПОЗИЦІЯ, ЩО МІСТИТЬ <font face="Symbol">b</font>2-АДРЕНЕРГІЧНИЙ АГОНІСТ ТРИВАЛОЇ ДІЇ, ДОЗУЮЧИЙ ІНГАЛЯТОР ПІД ТИСКОМ ТА СПОСІБ ЙОГО ЗАПОВНЕННЯ
US20060257324A1 (en) * 2000-05-22 2006-11-16 Chiesi Farmaceutici S.P.A. Pharmaceutical solution formulations for pressurised metered dose inhalers
PT3494995T (pt) * 2002-03-01 2020-03-30 Chiesi Farm Spa Formulação superfina de formoterol
EP1415647A1 (de) * 2002-10-23 2004-05-06 CHIESI FARMACEUTICI S.p.A. Langwirkende beta-2-Agonisten in ultrafeiner Formulierung
EP1340492A1 (de) * 2002-03-01 2003-09-03 CHIESI FARMACEUTICI S.p.A. Aerosolformulierungen zur pulmonalen Verabreichung von Arzneimitteln mit systemischer Wirkung
CA2388352A1 (en) * 2002-05-31 2003-11-30 Voiceage Corporation A method and device for frequency-selective pitch enhancement of synthesized speed
EP1595531A1 (de) * 2004-05-13 2005-11-16 CHIESI FARMACEUTICI S.p.A. Stabile Arzneimittellösung für Druckdosierinhalatoren

Also Published As

Publication number Publication date
EP1194121A1 (de) 2002-04-10
ATE523190T1 (de) 2011-09-15
EP1693053A3 (de) 2007-06-27
EP1693053A2 (de) 2006-08-23
US20050220717A1 (en) 2005-10-06
AU777505B2 (en) 2004-10-21
JP2003502357A (ja) 2003-01-21
US6315985B1 (en) 2001-11-13
EP1194121B1 (de) 2006-03-22
US6610273B2 (en) 2003-08-26
DE60026840T2 (de) 2006-10-12
EP1693053B1 (de) 2011-09-07
US20040033201A1 (en) 2004-02-19
WO2000078286A1 (en) 2000-12-28
CA2371931A1 (en) 2000-12-28
AU5614200A (en) 2001-01-09
DE60026840D1 (de) 2006-05-11
US20020071810A1 (en) 2002-06-13
JP4777560B2 (ja) 2011-09-21

Similar Documents

Publication Publication Date Title
ATE320794T1 (de) Aerosolprodukte von steroidlösung mit verbesserter chemischer stabilität
AU5762894A (en) Pharmaceutical compositions in semisolid form and a device for administration thereof
EP1525819A3 (de) Verpackung zum Spenden einer flie fähigen kosmetischen Zusammensetzung und eines Produktes
AU664651B2 (en) Squeezable tubular container and process for the production thereof
AU5599396A (en) Container for delivery of flowable material
IT1244181B (it) Apparecchio erogatore di liquidi sotto forma di getto nebulizzato, particolarmente quale nebulizzatore medicale
MY128732A (en) Container for a medical liquid
EP1143930B8 (de) Fluticasonpropionat arzneizubereitung
AU3761495A (en) Method for forming and packaging iontophoretic drug delivery patches and the like to increase stability and shelf-life
MX9603166A (es) Envase para productos, como pastillas y similares.
GB9517998D0 (en) Compositions and device for their administration
AU3533399A (en) A dispenser capsule for containers of liquid or semiliquid products
ES2127515T3 (es) Frasco de expedicion de producto.
NZ234183A (en) Container with tear-off seal: non metallic tear tab
AU5552494A (en) Liquid-tight non-adhesive stretch film as a container closure
AU2939992A (en) Flexible tube for the packaging of pasty products
AU2219201A (en) Device for the controlled delivery of liquids and/or creamy substances and/or flowable substances
AU114015S (en) Swan shaped air freshener liquid spray container
AU2001228976A1 (en) Reusable container for liquid products and method for producing the same
AU7812794A (en) Pharmaceutical compositions containing n-acetylcarnosine for the treatment of cataract
PL288702A1 (en) Packaging for liquid or powdered products
AU7988994A (en) An injectable solution of testosterone undecanoate
AR219171A1 (es) Sistema de pulverizacion en forma de aerosol,que comprende un recipiente;un producto pulverizable contenido en dicho recipiente,y un dispositivo de descarga asociado con el recipiente
EP0420047A3 (en) Device for the metered delivery or the application of liquid or pasty products
AU4594500A (en) Containers for cosmetic products and the like

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties