IT1034011B - Processo per la prapratzione di 17 monoesteri di 17 a 21 diossisteroidi per idrolisi die corpispondenti 17 21 ortoesteri ciclici a ph control lato - Google Patents

Processo per la prapratzione di 17 monoesteri di 17 a 21 diossisteroidi per idrolisi die corpispondenti 17 21 ortoesteri ciclici a ph control lato

Info

Publication number
IT1034011B
IT1034011B IT18717/69A IT1871769A IT1034011B IT 1034011 B IT1034011 B IT 1034011B IT 18717/69 A IT18717/69 A IT 18717/69A IT 1871769 A IT1871769 A IT 1871769A IT 1034011 B IT1034011 B IT 1034011B
Authority
IT
Italy
Prior art keywords
dioxysteroids
corpispondent
monoesters
dies
hydrolysis
Prior art date
Application number
IT18717/69A
Other languages
English (en)
Inventor
Romano Vitali
Alberto Ercoli
Rinaldo Gardi
Original Assignee
Vister Vismara Terapeutici S P
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vister Vismara Terapeutici S P filed Critical Vister Vismara Terapeutici S P
Priority to IT18717/69A priority Critical patent/IT1034011B/it
Priority to ZA704243A priority patent/ZA704243B/xx
Priority to GB1296458D priority patent/GB1296458A/en
Priority to DK321370AA priority patent/DK129988B/da
Priority to US00048481A priority patent/US3755302A/en
Priority to FR7022964A priority patent/FR2051186A5/fr
Priority to FI701737A priority patent/FI48186C/fi
Priority to NL7009254.A priority patent/NL162914C/xx
Priority to DE19702031205 priority patent/DE2031205C3/de
Priority to SE08839/70A priority patent/SE356976B/xx
Priority to NO2493/70A priority patent/NO133936C/no
Priority to CH974770A priority patent/CH583252A5/xx
Application granted granted Critical
Publication of IT1034011B publication Critical patent/IT1034011B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Prevention Of Electric Corrosion (AREA)
IT18717/69A 1969-06-26 1969-06-26 Processo per la prapratzione di 17 monoesteri di 17 a 21 diossisteroidi per idrolisi die corpispondenti 17 21 ortoesteri ciclici a ph control lato IT1034011B (it)

Priority Applications (12)

Application Number Priority Date Filing Date Title
IT18717/69A IT1034011B (it) 1969-06-26 1969-06-26 Processo per la prapratzione di 17 monoesteri di 17 a 21 diossisteroidi per idrolisi die corpispondenti 17 21 ortoesteri ciclici a ph control lato
ZA704243A ZA704243B (en) 1969-06-26 1969-07-22 Improvement in the preparation of 17-monoesters of 17alpha,21-dihydroxy-steroids
DK321370AA DK129988B (da) 1969-06-26 1970-06-22 Fremgangsmåde til fremstilling af 17-monoestere af 17α,21-dihydroxy-20-keto-steroidforbindelser af pregnanrækken.
US00048481A US3755302A (en) 1969-06-26 1970-06-22 Process for the production of 17-monesters of 17{60 , 21-dihydroxy-steroids and products thereof
GB1296458D GB1296458A (it) 1969-06-26 1970-06-22
FR7022964A FR2051186A5 (it) 1969-06-26 1970-06-22
FI701737A FI48186C (fi) 1969-06-26 1970-06-22 Parannettu tapa valmistaa 17alfa,21-dihydroksi-20-keto-steroidien 17-m onoestereitä
NL7009254.A NL162914C (nl) 1969-06-26 1970-06-24 Werkwijze voor de bereiding van 17-mono-esters uit 17 alfa,21-dihydroxy-20-keto-steroiden van de pregnaan- reeks, alsmede gevormd farmaceutisch preparaat met ontstekingswerende eigenschappen.
DE19702031205 DE2031205C3 (de) 1969-06-26 1970-06-24 Verfahren zur Herstellung von 17-Monoestern von 17 alpha, 21-Dihydroxy-20-ketosteroiden und Prednisolon-17benzoat
SE08839/70A SE356976B (it) 1969-06-26 1970-06-25
NO2493/70A NO133936C (it) 1969-06-26 1970-06-25
CH974770A CH583252A5 (it) 1969-06-26 1970-06-26

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT18717/69A IT1034011B (it) 1969-06-26 1969-06-26 Processo per la prapratzione di 17 monoesteri di 17 a 21 diossisteroidi per idrolisi die corpispondenti 17 21 ortoesteri ciclici a ph control lato

Publications (1)

Publication Number Publication Date
IT1034011B true IT1034011B (it) 1979-09-10

Family

ID=11153377

Family Applications (1)

Application Number Title Priority Date Filing Date
IT18717/69A IT1034011B (it) 1969-06-26 1969-06-26 Processo per la prapratzione di 17 monoesteri di 17 a 21 diossisteroidi per idrolisi die corpispondenti 17 21 ortoesteri ciclici a ph control lato

Country Status (11)

Country Link
US (1) US3755302A (it)
CH (1) CH583252A5 (it)
DK (1) DK129988B (it)
FI (1) FI48186C (it)
FR (1) FR2051186A5 (it)
GB (1) GB1296458A (it)
IT (1) IT1034011B (it)
NL (1) NL162914C (it)
NO (1) NO133936C (it)
SE (1) SE356976B (it)
ZA (1) ZA704243B (it)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3857941A (en) * 1970-06-22 1974-12-31 Warner Lambert Co Pharmaceutical compositions and use of prednisolone 17-benzoate
GB1440063A (en) * 1972-08-11 1976-06-23 Glaxo Lab Ltd 17alpha-esters of 17alpha,21-dihydroxy-20-oxo-steroids
US3992422A (en) * 1975-08-14 1976-11-16 Schering Corporation Process for the preparation of 21-halogeno-21-desoxy-17α-acyloxy-20-keto-pregnenes
DE3069074D1 (en) * 1979-11-16 1984-10-04 Sterosynt Ltd 6-alpha-9-alpha-difluoro-16-beta-methyl-prednisolone-17,21 diesters and pharmaceutical compositions containing them
US6315985B1 (en) * 1999-06-18 2001-11-13 3M Innovative Properties Company C-17/21 OH 20-ketosteroid solution aerosol products with enhanced chemical stability
GB0019172D0 (en) 2000-08-05 2000-09-27 Glaxo Group Ltd Novel compounds
US6858596B2 (en) * 2000-08-05 2005-02-22 Smithkline Beecham Corporation Formulation containing anti-inflammatory androstane derivative
US6759398B2 (en) * 2000-08-05 2004-07-06 Smithkline Beecham Corporation Anti-inflammatory androstane derivative
SK287576B6 (sk) * 2000-08-05 2011-03-04 Glaxo Group Limited S-fluórmetylester kyseliny 6alfa, 9alfa-difluór-17alfa-[(2- furanylkarboxyl)oxy]-11beta-hydroxy-16alfa-metyl-3-oxo-androsta- 1,4-dién-17beta-karbotiovej, spôsob jeho prípravy, farmaceutický prostriedok s jeho obsahom, jeho použitie a medziprodukty
US6777399B2 (en) * 2000-08-05 2004-08-17 Smithkline Beecham Corporation Anti-inflammatory androstane derivative compositions
AR033290A1 (es) * 2001-04-30 2003-12-10 Glaxo Group Ltd Derivados antiinflamatorios de androstano
WO2002100879A1 (en) * 2001-06-12 2002-12-19 Glaxo Group Limited Novel anti-inflammatory 17.alpha.-heterocyclic-esters of 17.beta.carbothioate androstane derivatives
US20050175545A1 (en) * 2002-02-04 2005-08-11 Keith Biggadike Formulation for inhalation comprising a glucocorticoid and a beta 2-adrenoreceptor agonist
GB0202635D0 (en) * 2002-02-05 2002-03-20 Glaxo Wellcome Mfg Pte Ltd Formulation containing novel anti-inflammatory androstane derivative
GB2389530B (en) 2002-06-14 2007-01-10 Cipla Ltd Pharmaceutical compositions
GB0507165D0 (en) * 2005-04-08 2005-05-18 Glaxo Group Ltd Novel crystalline pharmaceutical product
GB0615108D0 (en) * 2006-07-28 2006-09-06 Glaxo Group Ltd Novel formulations
CN102964414A (zh) * 2012-12-14 2013-03-13 中国科学院上海有机化学研究所 17位甾体羧酸酯的合成方法
CN115010198B (zh) * 2022-07-11 2023-05-09 西安国康瑞金制药有限公司 一种整合在倍他米松上氟中的废水处理工艺

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2897216A (en) * 1954-11-01 1959-07-28 Schering Corp Process for the preparation of steroidal dienes and intermediates obtained thereby
GB1070751A (en) * 1964-01-28 1967-06-01 Glaxo Lab Ltd 17-esters of 17-hydroxy-21-desoxy-steroids
US3345387A (en) * 1964-05-25 1967-10-03 Merck & Co Inc Process for producing 16beta-alkyl and 16beta-alkyl steroids of the pregnane series
US3499081A (en) * 1966-12-21 1970-03-03 Squibb & Sons Inc 9-chloroprogestational agents
IT1061787B (it) * 1967-03-01 1983-04-30 Vismara Francesco Spa Miglioramenti relativi alla preparazione di 17 benzoato di betametazone
US3455968A (en) * 1967-05-15 1969-07-15 Schering Corp 9alpha-halogeno-11beta-azido-steroids and methods for their manufacture

Also Published As

Publication number Publication date
DE2031205A1 (de) 1971-02-04
NL7009254A (it) 1970-12-29
ZA704243B (en) 1971-03-31
GB1296458A (it) 1972-11-15
NO133936B (it) 1976-04-12
CH583252A5 (it) 1976-12-31
DK129988B (da) 1974-12-09
DK129988C (it) 1975-06-23
FI48186C (fi) 1974-07-10
NL162914B (nl) 1980-02-15
NL162914C (nl) 1980-07-15
US3755302A (en) 1973-08-28
NO133936C (it) 1976-07-21
FR2051186A5 (it) 1971-04-02
SE356976B (it) 1973-06-12
FI48186B (it) 1974-04-01
DE2031205B2 (de) 1975-09-25

Similar Documents

Publication Publication Date Title
IT1034011B (it) Processo per la prapratzione di 17 monoesteri di 17 a 21 diossisteroidi per idrolisi die corpispondenti 17 21 ortoesteri ciclici a ph control lato
IT1048136B (it) Processo per la produzione di alfa olefine
IT1045517B (it) Metodo per la produzione di color caramello
FR1468050A (fr) Procédé de production de l'acide phosphorique
BE760672A (fr) Procede de production d'alcenes
BE756218A (fr) Procede de production d'acides imidocarboxyliques
FR1543753A (fr) Procédé de production d'acide phosphorique
BE777349A (fr) Procede de fabrication de diuranate d'ammonium
IT941664B (it) Processo per produrre alcooli
IT999077B (it) Processo per la produzione di alcooli alifatici
IT1056058B (it) Processo per produrre chinossalin di a ossidi
IT1005111B (it) Processo per ottenere resorcina
CH490344A (fr) Procédé de production d'urée
FR1484782A (fr) Procédé de production d'amines
IT977950B (it) Processo per chiarificare brodi di fermentazione
FR1480663A (fr) Procédé de production d'acide phosphorique
CH479519A (fr) Procédé de production d'acides méthylolalcanoïques
FR1488064A (fr) Procédé de production de chlorures d'acides chloroaliphatiques
IT941432B (it) Processo per la produzione di imidazoisochinolindioni
FR1491404A (fr) Procédé perfectionné de production de l'urée
CH481872A (fr) Procédé de production de 1,1'-peroxydicyclohexylamine
FR1493184A (fr) Procédé de production d'acide fluorhydrique
BR7106575D0 (pt) Um processo de producao de glicose por cisao inzimatica de polissacarideos
FR1491197A (fr) Procédé de production d'inosine
FR1482256A (fr) Procédé de production d'inosine