DK129988B - Fremgangsmåde til fremstilling af 17-monoestere af 17α,21-dihydroxy-20-keto-steroidforbindelser af pregnanrækken. - Google Patents

Fremgangsmåde til fremstilling af 17-monoestere af 17α,21-dihydroxy-20-keto-steroidforbindelser af pregnanrækken.

Info

Publication number
DK129988B
DK129988B DK321370AA DK321370A DK129988B DK 129988 B DK129988 B DK 129988B DK 321370A A DK321370A A DK 321370AA DK 321370 A DK321370 A DK 321370A DK 129988 B DK129988 B DK 129988B
Authority
DK
Denmark
Prior art keywords
monoesters
keto
dihydroxy
preparation
steroid compounds
Prior art date
Application number
DK321370AA
Other languages
English (en)
Other versions
DK129988C (da
Inventor
A Ercoli
R Gardi
R Vitali
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of DK129988B publication Critical patent/DK129988B/da
Application granted granted Critical
Publication of DK129988C publication Critical patent/DK129988C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Prevention Of Electric Corrosion (AREA)
DK321370AA 1969-06-26 1970-06-22 Fremgangsmåde til fremstilling af 17-monoestere af 17α,21-dihydroxy-20-keto-steroidforbindelser af pregnanrækken. DK129988B (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT18717/69A IT1034011B (it) 1969-06-26 1969-06-26 Processo per la prapratzione di 17 monoesteri di 17 a 21 diossisteroidi per idrolisi die corpispondenti 17 21 ortoesteri ciclici a ph control lato

Publications (2)

Publication Number Publication Date
DK129988B true DK129988B (da) 1974-12-09
DK129988C DK129988C (da) 1975-06-23

Family

ID=11153377

Family Applications (1)

Application Number Title Priority Date Filing Date
DK321370AA DK129988B (da) 1969-06-26 1970-06-22 Fremgangsmåde til fremstilling af 17-monoestere af 17α,21-dihydroxy-20-keto-steroidforbindelser af pregnanrækken.

Country Status (11)

Country Link
US (1) US3755302A (da)
CH (1) CH583252A5 (da)
DK (1) DK129988B (da)
FI (1) FI48186C (da)
FR (1) FR2051186A5 (da)
GB (1) GB1296458A (da)
IT (1) IT1034011B (da)
NL (1) NL162914C (da)
NO (1) NO133936C (da)
SE (1) SE356976B (da)
ZA (1) ZA704243B (da)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3857941A (en) * 1970-06-22 1974-12-31 Warner Lambert Co Pharmaceutical compositions and use of prednisolone 17-benzoate
GB1440063A (en) * 1972-08-11 1976-06-23 Glaxo Lab Ltd 17alpha-esters of 17alpha,21-dihydroxy-20-oxo-steroids
US3992422A (en) * 1975-08-14 1976-11-16 Schering Corporation Process for the preparation of 21-halogeno-21-desoxy-17α-acyloxy-20-keto-pregnenes
DE3069074D1 (en) * 1979-11-16 1984-10-04 Sterosynt Ltd 6-alpha-9-alpha-difluoro-16-beta-methyl-prednisolone-17,21 diesters and pharmaceutical compositions containing them
US6315985B1 (en) * 1999-06-18 2001-11-13 3M Innovative Properties Company C-17/21 OH 20-ketosteroid solution aerosol products with enhanced chemical stability
GB0019172D0 (en) 2000-08-05 2000-09-27 Glaxo Group Ltd Novel compounds
US6858596B2 (en) * 2000-08-05 2005-02-22 Smithkline Beecham Corporation Formulation containing anti-inflammatory androstane derivative
US6759398B2 (en) * 2000-08-05 2004-07-06 Smithkline Beecham Corporation Anti-inflammatory androstane derivative
SK287576B6 (sk) * 2000-08-05 2011-03-04 Glaxo Group Limited S-fluórmetylester kyseliny 6alfa, 9alfa-difluór-17alfa-[(2- furanylkarboxyl)oxy]-11beta-hydroxy-16alfa-metyl-3-oxo-androsta- 1,4-dién-17beta-karbotiovej, spôsob jeho prípravy, farmaceutický prostriedok s jeho obsahom, jeho použitie a medziprodukty
US6777399B2 (en) * 2000-08-05 2004-08-17 Smithkline Beecham Corporation Anti-inflammatory androstane derivative compositions
AR033290A1 (es) * 2001-04-30 2003-12-10 Glaxo Group Ltd Derivados antiinflamatorios de androstano
WO2002100879A1 (en) * 2001-06-12 2002-12-19 Glaxo Group Limited Novel anti-inflammatory 17.alpha.-heterocyclic-esters of 17.beta.carbothioate androstane derivatives
US20050175545A1 (en) * 2002-02-04 2005-08-11 Keith Biggadike Formulation for inhalation comprising a glucocorticoid and a beta 2-adrenoreceptor agonist
GB0202635D0 (en) * 2002-02-05 2002-03-20 Glaxo Wellcome Mfg Pte Ltd Formulation containing novel anti-inflammatory androstane derivative
GB2389530B (en) 2002-06-14 2007-01-10 Cipla Ltd Pharmaceutical compositions
GB0507165D0 (en) * 2005-04-08 2005-05-18 Glaxo Group Ltd Novel crystalline pharmaceutical product
GB0615108D0 (en) * 2006-07-28 2006-09-06 Glaxo Group Ltd Novel formulations
CN102964414A (zh) * 2012-12-14 2013-03-13 中国科学院上海有机化学研究所 17位甾体羧酸酯的合成方法
CN115010198B (zh) * 2022-07-11 2023-05-09 西安国康瑞金制药有限公司 一种整合在倍他米松上氟中的废水处理工艺

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2897216A (en) * 1954-11-01 1959-07-28 Schering Corp Process for the preparation of steroidal dienes and intermediates obtained thereby
GB1070751A (en) * 1964-01-28 1967-06-01 Glaxo Lab Ltd 17-esters of 17-hydroxy-21-desoxy-steroids
US3345387A (en) * 1964-05-25 1967-10-03 Merck & Co Inc Process for producing 16beta-alkyl and 16beta-alkyl steroids of the pregnane series
US3499081A (en) * 1966-12-21 1970-03-03 Squibb & Sons Inc 9-chloroprogestational agents
IT1061787B (it) * 1967-03-01 1983-04-30 Vismara Francesco Spa Miglioramenti relativi alla preparazione di 17 benzoato di betametazone
US3455968A (en) * 1967-05-15 1969-07-15 Schering Corp 9alpha-halogeno-11beta-azido-steroids and methods for their manufacture

Also Published As

Publication number Publication date
DE2031205A1 (de) 1971-02-04
NL7009254A (da) 1970-12-29
ZA704243B (en) 1971-03-31
GB1296458A (da) 1972-11-15
NO133936B (da) 1976-04-12
CH583252A5 (da) 1976-12-31
DK129988C (da) 1975-06-23
FI48186C (fi) 1974-07-10
NL162914B (nl) 1980-02-15
NL162914C (nl) 1980-07-15
US3755302A (en) 1973-08-28
NO133936C (da) 1976-07-21
FR2051186A5 (da) 1971-04-02
SE356976B (da) 1973-06-12
FI48186B (da) 1974-04-01
DE2031205B2 (de) 1975-09-25
IT1034011B (it) 1979-09-10

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