ATE318815T1 - Verfahren zur herstellung von enantiomeren von indol-2,3-dion-3-oximderivaten - Google Patents
Verfahren zur herstellung von enantiomeren von indol-2,3-dion-3-oximderivatenInfo
- Publication number
- ATE318815T1 ATE318815T1 AT03792147T AT03792147T ATE318815T1 AT E318815 T1 ATE318815 T1 AT E318815T1 AT 03792147 T AT03792147 T AT 03792147T AT 03792147 T AT03792147 T AT 03792147T AT E318815 T1 ATE318815 T1 AT E318815T1
- Authority
- AT
- Austria
- Prior art keywords
- dione
- indole
- oxime derivatives
- producing enantiomers
- enantiomers
- Prior art date
Links
- LNMAXZZQNSPQSR-UHFFFAOYSA-N 3-(hydroxyamino)indol-2-one Chemical class C1=CC=CC2=NC(=O)C(NO)=C21 LNMAXZZQNSPQSR-UHFFFAOYSA-N 0.000 title abstract 2
- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical compound C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/02—Oxygen as only ring hetero atoms
- C12P17/04—Oxygen as only ring hetero atoms containing a five-membered hetero ring, e.g. griseofulvin, vitamin C
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
- C12P41/003—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
- C12P41/004—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of alcohol- or thiol groups in the enantiomers or the inverse reaction
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200201237 | 2002-08-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE318815T1 true ATE318815T1 (de) | 2006-03-15 |
Family
ID=31896777
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03792147T ATE318815T1 (de) | 2002-08-22 | 2003-08-13 | Verfahren zur herstellung von enantiomeren von indol-2,3-dion-3-oximderivaten |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US7632948B2 (https=) |
| EP (1) | EP1532146B1 (https=) |
| JP (1) | JP2006503011A (https=) |
| CN (1) | CN1296372C (https=) |
| AT (1) | ATE318815T1 (https=) |
| AU (1) | AU2003250323A1 (https=) |
| CA (1) | CA2493244A1 (https=) |
| DE (1) | DE60303825T2 (https=) |
| DK (1) | DK1532146T3 (https=) |
| MX (1) | MXPA05002056A (https=) |
| NZ (1) | NZ537810A (https=) |
| WO (1) | WO2004018466A2 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1183025T3 (da) | 1999-05-19 | 2009-05-04 | Painceptor Pharma Corp | Hæmmere af proton-styrede kationskanaler og deres anvendelse til behandling af iskæmiske lidelser |
| GT200600180A (es) * | 2005-04-29 | 2006-11-22 | Proceso para preparar isatinas con control de formacion de subproductos | |
| WO2007059608A1 (en) | 2005-11-23 | 2007-05-31 | Painceptor Pharma Corporation | Compositions and methods for modulating gated ion channels |
| CA2652307A1 (en) * | 2006-04-10 | 2007-10-18 | Painceptor Pharma Corporation | Compositions and methods for modulating gated ion channels |
| US20090246134A1 (en) * | 2007-05-30 | 2009-10-01 | Painceptor Pharma Corporation | Compositions and methods for modulating gated ion channels |
| AU2016359230B2 (en) | 2015-11-25 | 2020-04-23 | Ligachem Biosciences Inc. | Conjugates comprising self-immolative groups and methods related thereto |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2542941B2 (ja) * | 1990-02-02 | 1996-10-09 | チッソ株式会社 | 光学活性ヒドロキシラクトン類の製造方法 |
| JP2939646B2 (ja) * | 1990-07-17 | 1999-08-25 | チッソ株式会社 | ４―置換―２―ヒドロキシブタン酸エステルおよび製造法 |
| JP3789951B2 (ja) * | 1993-11-25 | 2006-06-28 | 三共アグロ株式会社 | Ｏ−ｎ結合を有する糖誘導体及び製造方法 |
| UA54403C2 (uk) * | 1996-10-01 | 2003-03-17 | Н'Юросерч А/С | Похідні індол-2,3-діон-3-оксиму, фармацевтична композиція, спосіб лікування розладу чи захворювання ссавців, у тому числі людини та спосіб одержання похідних індол-2,3-діон-3-оксиму |
| EP1066037B1 (en) * | 1998-03-31 | 2004-12-29 | Neurosearch A/S | Use of indole-2,3-dione-3-oxime derivatives as ampa antagonists |
| WO2001018231A2 (de) * | 1999-09-08 | 2001-03-15 | Lonza Ag | VERFAHREN ZUR HERSTELLUNG VON (R)- ODER (S)-HYDROXY-η-BUTYROLACTON |
-
2003
- 2003-08-13 DE DE60303825T patent/DE60303825T2/de not_active Expired - Lifetime
- 2003-08-13 DK DK03792147T patent/DK1532146T3/da active
- 2003-08-13 AT AT03792147T patent/ATE318815T1/de not_active IP Right Cessation
- 2003-08-13 JP JP2004529729A patent/JP2006503011A/ja active Pending
- 2003-08-13 AU AU2003250323A patent/AU2003250323A1/en not_active Abandoned
- 2003-08-13 NZ NZ537810A patent/NZ537810A/en unknown
- 2003-08-13 CA CA002493244A patent/CA2493244A1/en not_active Abandoned
- 2003-08-13 WO PCT/DK2003/000539 patent/WO2004018466A2/en not_active Ceased
- 2003-08-13 MX MXPA05002056A patent/MXPA05002056A/es active IP Right Grant
- 2003-08-13 EP EP03792147A patent/EP1532146B1/en not_active Expired - Lifetime
- 2003-08-13 CN CNB03818396XA patent/CN1296372C/zh not_active Expired - Fee Related
- 2003-08-13 US US10/524,441 patent/US7632948B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JP2006503011A (ja) | 2006-01-26 |
| DK1532146T3 (da) | 2006-07-03 |
| US20060178391A1 (en) | 2006-08-10 |
| EP1532146A2 (en) | 2005-05-25 |
| US7632948B2 (en) | 2009-12-15 |
| CA2493244A1 (en) | 2004-03-04 |
| CN1671704A (zh) | 2005-09-21 |
| MXPA05002056A (es) | 2005-06-08 |
| NZ537810A (en) | 2006-10-27 |
| CN1296372C (zh) | 2007-01-24 |
| DE60303825D1 (de) | 2006-04-27 |
| DE60303825T2 (de) | 2006-08-17 |
| WO2004018466A3 (en) | 2004-03-25 |
| EP1532146B1 (en) | 2006-03-01 |
| WO2004018466A2 (en) | 2004-03-04 |
| AU2003250323A1 (en) | 2004-03-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1532146 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |