ATE315934T1 - Thrombopoietin-mimetika - Google Patents
Thrombopoietin-mimetikaInfo
- Publication number
- ATE315934T1 ATE315934T1 AT00961674T AT00961674T ATE315934T1 AT E315934 T1 ATE315934 T1 AT E315934T1 AT 00961674 T AT00961674 T AT 00961674T AT 00961674 T AT00961674 T AT 00961674T AT E315934 T1 ATE315934 T1 AT E315934T1
- Authority
- AT
- Austria
- Prior art keywords
- mammal
- invented
- thrombopoietin mimetics
- mimetics
- thrombopoietin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/44—Oxygen and nitrogen or sulfur and nitrogen atoms
- C07D231/46—Oxygen atom in position 3 or 5 and nitrogen atom in position 4
- C07D231/48—Oxygen atom in position 3 or 5 and nitrogen atom in position 4 with hydrocarbon radicals attached to said nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/655—Azo (—N=N—), diazo (=N2), azoxy (>N—O—N< or N(=O)—N<), azido (—N3) or diazoamino (—N=N—N<) compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US15335899P | 1999-09-10 | 1999-09-10 | |
US20366800P | 2000-05-12 | 2000-05-12 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE315934T1 true ATE315934T1 (de) | 2006-02-15 |
Family
ID=26850465
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT00961674T ATE315934T1 (de) | 1999-09-10 | 2000-09-08 | Thrombopoietin-mimetika |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP1213965B1 (de) |
JP (1) | JP4488663B2 (de) |
AT (1) | ATE315934T1 (de) |
AU (1) | AU770564B2 (de) |
DE (1) | DE60025632T2 (de) |
ES (1) | ES2256038T3 (de) |
WO (1) | WO2001017349A1 (de) |
Families Citing this family (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CY2010012I2 (el) | 2000-05-25 | 2020-05-29 | Novartis Ag | Μιμητικα θρομβοποιητινης |
AU2001260661A1 (en) | 2000-05-30 | 2001-12-11 | Chugai Seiyaku Kabushiki Kaisha | Compounds exhibiting thrombopoietin-like activities |
EP1370252A4 (de) * | 2001-03-01 | 2006-04-05 | Smithkline Beecham Corp | Thrombopoietin-mimetika |
AR040083A1 (es) | 2002-05-22 | 2005-03-16 | Smithkline Beecham Corp | Compuesto bis-(monoetanolamina) del acido 3'-[(2z)-[1-(3,4-dimetilfenil) -1,5-dihidro-3-metil-5-oxo-4h-pirazol-4-iliden] hidrazino] -2'-hidroxi-[1,1'-bifenil]-3-carboxilico, procedimiento para prepararlo, composicion farmaceutica que lo comprende, procedimiento para preparar dicha composicion farmac |
JP4412173B2 (ja) | 2002-08-14 | 2010-02-10 | 日産化学工業株式会社 | トロンボポエチンレセプター活性化剤ならびにそれらの製造方法 |
TWI324593B (en) | 2002-10-09 | 2010-05-11 | Nissan Chemical Ind Ltd | Pyrazolone compounds and thrombopoietin receptor activator |
TW200526638A (en) | 2003-10-22 | 2005-08-16 | Smithkline Beecham Corp | 2-(3,4-dimethylphenyl)-4-{[2-hydroxy-3'-(1H-tetrazol-5-yl)biphenyl-3-yl]-hydrazono}-5-methyl-2,4-dihydropyrazol-3-one choline |
WO2005118551A2 (en) | 2004-05-28 | 2005-12-15 | Ligand Pharmaceuticals Inc. | Thrombopoietin activity modulating compounds and methods |
AU2005299720B2 (en) | 2004-10-25 | 2010-02-04 | Ligand Pharmaceuticals Incorporated | Thrombopoietin activity modulating compounds and methods |
CA2588979C (en) | 2004-12-08 | 2013-01-22 | Nissan Chemical Industries, Ltd. | 3-ethylidenehydrazino substituted heterocyclic compounds as thrombopoietin receptor activators |
WO2006064957A1 (ja) | 2004-12-14 | 2006-06-22 | Nissan Chemical Industries, Ltd. | アミド化合物及びトロンボポエチンレセプター活性化剤 |
TWI368617B (en) | 2005-07-15 | 2012-07-21 | Nissan Chemical Ind Ltd | Thiophene compounds and thrombopoietin receptor activators |
WO2007011056A1 (en) | 2005-07-20 | 2007-01-25 | Nissan Chemical Industries, Ltd. | Pyrazole compounds and thrombopoietin receptor activators |
US20100179161A1 (en) * | 2005-08-19 | 2010-07-15 | Astrazeneca Ab | Pyrazoline derivatives for the treatment of turberculosis |
EP1947101A4 (de) | 2005-11-07 | 2009-09-16 | Nissan Chemical Ind Ltd | Hydrazidverbindung und thrombopoietinrezeptoraktivator |
WO2007062078A2 (en) * | 2005-11-23 | 2007-05-31 | Ligand Pharmaceuticals Inc. | Thrombopoietin activity modulating compounds and methods |
WO2007142308A1 (ja) | 2006-06-07 | 2007-12-13 | Nissan Chemical Industries, Ltd. | 含窒素ヘテロ環化合物及びトロンボポエチンレセプター活性化剤 |
US7786159B2 (en) | 2006-12-01 | 2010-08-31 | Stategics, Inc. | Thrombopoietin mimetics |
ECSP077628A (es) | 2007-05-03 | 2008-12-30 | Smithkline Beechman Corp | Nueva composición farmacéutica |
CN101481352A (zh) | 2008-01-10 | 2009-07-15 | 上海恒瑞医药有限公司 | 双环取代吡唑酮偶氮类衍生物、其制备方法及其在医药上的应用 |
PE20100362A1 (es) | 2008-10-30 | 2010-05-27 | Irm Llc | Derivados de purina que expanden las celulas madre hematopoyeticas |
JP2012528184A (ja) | 2009-05-29 | 2012-11-12 | グラクソスミスクライン・リミテッド・ライアビリティ・カンパニー | トロンボポエチンアゴニスト化合物の投与の方法 |
CN101921232A (zh) | 2009-06-11 | 2010-12-22 | 上海恒瑞医药有限公司 | 双环取代吡唑酮偶氮类衍生物的盐,其制备方法及其在医药上的应用 |
WO2012102937A2 (en) | 2011-01-25 | 2012-08-02 | Irm Llc | Compounds that expand hematopoietic stem cells |
CA2858069C (en) | 2011-12-08 | 2020-02-11 | Fred Hutchinson Cancer Research Center | Compositions and methods for enhanced generation of hematopoietic stem/progenitor cells |
NZ627188A (en) | 2012-01-27 | 2015-12-24 | Univ Montreal | Pyrimido[4,5-b]indole derivatives and use thereof in the expansion of hematopoietic stem cells |
CN103232730B (zh) * | 2013-01-10 | 2015-01-14 | 浙江山峪染料化工有限公司 | 一种混拼型分散黄染料 |
CN103232729A (zh) * | 2013-01-10 | 2013-08-07 | 浙江山峪染料化工有限公司 | 多组份拼混型分散黄染料配方 |
CN103232728B (zh) * | 2013-01-10 | 2014-08-20 | 浙江山峪染料化工有限公司 | 混拼型分散黄染料 |
CN103232727B (zh) * | 2013-01-10 | 2014-09-03 | 浙江山峪染料化工有限公司 | 一种多组份拼混型分散黄染料 |
CN103044968B (zh) * | 2013-01-11 | 2014-10-22 | 浙江山峪染料化工有限公司 | 一种分散黄染料 |
ES2788977T3 (es) | 2014-04-22 | 2020-10-23 | Univ Montreal | Compuestos y uso de los mismos en la expansión de células madre hematopoyéticas y/o células progenitoras hematopoyéticas |
SG11201703407UA (en) | 2014-10-31 | 2017-05-30 | Nissan Chemical Ind Ltd | Ligand-binding fiber and cell culture substrate using said fiber |
WO2020113094A1 (en) | 2018-11-30 | 2020-06-04 | Nuvation Bio Inc. | Pyrrole and pyrazole compounds and methods of use thereof |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5482546A (en) * | 1994-03-30 | 1996-01-09 | Canon Kabushiki Kaisha | Dye, ink containing the same, and ink-jet recording method and instrument using the ink |
GC0000177A (en) * | 1998-12-17 | 2006-03-29 | Smithkline Beecham | Thrombopoietin mimetics |
-
2000
- 2000-09-08 ES ES00961674T patent/ES2256038T3/es not_active Expired - Lifetime
- 2000-09-08 WO PCT/US2000/024665 patent/WO2001017349A1/en active IP Right Grant
- 2000-09-08 JP JP2001521152A patent/JP4488663B2/ja not_active Expired - Fee Related
- 2000-09-08 EP EP00961674A patent/EP1213965B1/de not_active Expired - Lifetime
- 2000-09-08 AU AU73594/00A patent/AU770564B2/en not_active Ceased
- 2000-09-08 AT AT00961674T patent/ATE315934T1/de not_active IP Right Cessation
- 2000-09-08 DE DE60025632T patent/DE60025632T2/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
AU770564B2 (en) | 2004-02-26 |
DE60025632T2 (de) | 2006-08-10 |
DE60025632D1 (de) | 2006-04-06 |
ES2256038T3 (es) | 2006-07-16 |
WO2001017349A1 (en) | 2001-03-15 |
EP1213965A4 (de) | 2003-05-02 |
EP1213965A1 (de) | 2002-06-19 |
JP2003508463A (ja) | 2003-03-04 |
EP1213965B1 (de) | 2006-01-18 |
AU7359400A (en) | 2001-04-10 |
JP4488663B2 (ja) | 2010-06-23 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE350044T1 (de) | Thrombopoietinmimetika | |
ATE315934T1 (de) | Thrombopoietin-mimetika | |
DE60031714D1 (de) | Thrombopoietin-mimetika | |
MY136707A (en) | Thrombopoietin mimetics | |
WO2002049413A3 (en) | Thrombopoietin mimetics | |
WO2004054515A3 (en) | Thrombopoietin mimetics | |
EP1133291A4 (de) | Verfahren zur behandlung der thrombozytopenie | |
CY1108221T1 (el) | Μεθοδος για την αναπαραγωγη πλευρομουτιλινων | |
DE60124684D1 (de) | Sulfonamido-substituierte verbrückte bicycloalkylderivative | |
DE60001421D1 (de) | Behandlung von abgas | |
DE60101265D1 (de) | Behandlung von augenschmerzen | |
ATE203519T1 (de) | Chinolinderivate als antimalariamittel | |
ATE516027T1 (de) | Orazamid orotat zur vorbeugung von leberschäden | |
DK1305037T3 (da) | Smertestillende medikament | |
DE60103685D1 (de) | Behandlung von Poriomania | |
DE60110748D1 (de) | Behandlung von fluorkohlenstoff-beschickungen | |
ATE302008T1 (de) | Behandlung von entzündlichen erkrankungen | |
CY1106363T1 (el) | Χρηση του ενepγοποιημενου παραγοντα πηξης vii για την αγωγη των επαγομενων απο θρομβολυτικη θepαπεια μειζονων αιμορραγιων | |
EA200100785A1 (ru) | Шипучие слабительные средства | |
DE60125035D1 (de) | Behandlung von plasmid-haltigen lösungen | |
LU91009B1 (de) | Behandlung von Verbrennungen | |
DE60019921D1 (de) | Verwendung von interleukin-11 zur behandlung von hämoragischem schock | |
UA35854A (uk) | Спосіб лікування приховано протікаючого силікотуберкульозу |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |