ATE312615T1 - Zusammensetzung zur behandlung von schäden des gelenkknorpels - Google Patents

Zusammensetzung zur behandlung von schäden des gelenkknorpels

Info

Publication number
ATE312615T1
ATE312615T1 AT02751903T AT02751903T ATE312615T1 AT E312615 T1 ATE312615 T1 AT E312615T1 AT 02751903 T AT02751903 T AT 02751903T AT 02751903 T AT02751903 T AT 02751903T AT E312615 T1 ATE312615 T1 AT E312615T1
Authority
AT
Austria
Prior art keywords
composition
treatment
damage
articular cartilage
stem cells
Prior art date
Application number
AT02751903T
Other languages
English (en)
Inventor
Chul-Won Ha
Yoon-Sun Yang
Sung-Eun Yang
Original Assignee
Medipost Co Ltd
Chul-Won Ha
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medipost Co Ltd, Chul-Won Ha filed Critical Medipost Co Ltd
Application granted granted Critical
Publication of ATE312615T1 publication Critical patent/ATE312615T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48—Reproductive organs
    • A61K35/51—Umbilical cord; Umbilical cord blood; Umbilical stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
AT02751903T 2001-08-14 2002-08-14 Zusammensetzung zur behandlung von schäden des gelenkknorpels ATE312615T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR20010049147 2001-08-14
KR20010049148 2001-08-14
PCT/KR2002/001552 WO2003015802A1 (en) 2001-08-14 2002-08-14 Composition for treatment of articular cartilage damage

Publications (1)

Publication Number Publication Date
ATE312615T1 true ATE312615T1 (de) 2005-12-15

Family

ID=36746258

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02751903T ATE312615T1 (de) 2001-08-14 2002-08-14 Zusammensetzung zur behandlung von schäden des gelenkknorpels

Country Status (8)

Country Link
US (4) US7459307B2 (de)
EP (1) EP1416944B1 (de)
JP (2) JP4959916B2 (de)
KR (1) KR100494265B1 (de)
CN (1) CN1272022C (de)
AT (1) ATE312615T1 (de)
DE (1) DE60208042T2 (de)
WO (1) WO2003015802A1 (de)

Families Citing this family (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1229940T3 (da) 1999-11-15 2014-08-18 Piramal Healthcare Canada Ltd Temperaturstyret og ph-afhængig selvgelerende, vandig biopolymeropløsning
EP1237585B1 (de) * 1999-12-09 2003-06-18 Biosyntech Canada Inc. Mineral-polymer hybrid-zusammensetzung
US20030158302A1 (en) 1999-12-09 2003-08-21 Cyric Chaput Mineral-polymer hybrid composition
MXPA03000203A (es) 2000-06-29 2004-09-13 Biosyntech Canada Inc Composicion y metodo para la reparacion y regeneracion del cartilago y otros tejidos.
JP4959916B2 (ja) * 2001-08-14 2012-06-27 メディポスト・カンパニー・リミテッド 関節軟骨損傷治療用組成物
US20050118714A1 (en) * 2002-02-19 2005-06-02 Chul-Won Ha Isolation and culture-expansion methods of mesenchymal stem/progenitor cells from umbilical cord blood and differentation method of umbilical cord blood-derived mesenchymal stem/progenitor cells into various mesenchymal tissues
AR047712A1 (es) 2002-09-07 2006-02-15 Royal Veterinary College Metodo de tratamiento de una lesion de tejido esqueletico blando natural administrando una composicion de celulas madre mesenquimatosas
US8119397B2 (en) 2004-03-31 2012-02-21 Two Cells Co., Ltd. Therapeutic agents and therapeutic methods for treating injured tissue
AU2005241008C1 (en) 2004-04-23 2010-11-04 Bioe, Inc. Multi-Lineage Progenitor Cells
GB0511723D0 (en) * 2005-06-09 2005-07-13 Smith & Nephew Placental stem cells
CA2628313A1 (en) * 2005-11-04 2007-05-31 Bio Syntech Canada Inc. Composition and method for efficient delivery of nucleic acids to cells using chitosan
US20070178073A1 (en) * 2006-02-01 2007-08-02 Samsung Life Public Welfare Foundation Composition Comprising Separated or Proliferated Cells from Umbilical Cord Blood for Treating Developmental and/or Chronic Lung Disease
KR100834718B1 (ko) * 2006-09-20 2008-06-02 세원셀론텍(주) 뼈 재생을 도모하는 뼈 형성 촉진 세포조성물 및 그 제조방법
US20080311087A1 (en) * 2007-06-15 2008-12-18 Anna Gosiewska Human Umbilical Tissue-Derived Cell Compositions for the Treatment of Incontinence
WO2008157059A1 (en) * 2007-06-15 2008-12-24 Ethicon, Inc. Tissue fragment compositions for the treatment of incontinence
KR100905900B1 (ko) 2007-07-24 2009-07-02 (주)씨네이처 콜라겐을 함유한 관절연골 치료용 이중 지지체
CN101835479A (zh) * 2007-07-25 2010-09-15 佰欧益有限公司 多系祖细胞分化为软骨细胞
NZ601497A (en) 2008-08-20 2014-03-28 Anthrogenesis Corp Improved cell composition and methods of making the same
KR20100056718A (ko) * 2008-11-20 2010-05-28 한국과학기술연구원 형상회복력을 갖는 고탄성 생분해성 고분자 지지체 및 이를이용한 관절 연골 손상의 치료
WO2010114319A2 (ko) * 2009-03-31 2010-10-07 코오롱생명과학(주) 골재생용 조성물
EP2752483B1 (de) * 2009-05-13 2018-01-17 Medipost, Co., Ltd. Mit Stammzellenaktivitäten assoziiertes TSP-1, TSP-2, IL-17BR und HB-EGF und Anwendungen davon
US9040298B2 (en) 2009-05-29 2015-05-26 Medipost Co., Ltd. Method of selecting stem cells having high chondrogenic differentiation capability
FR2948286B1 (fr) * 2009-07-27 2011-08-26 Jean-Noel Thorel Composition injectable associant un agent de comblement et un milieu de croissance des fibroblastes
US8574614B2 (en) * 2010-02-04 2013-11-05 Hwa-Chang Liu Surgical grafts for repairing chondral defects
US8883210B1 (en) 2010-05-14 2014-11-11 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
US9352003B1 (en) 2010-05-14 2016-05-31 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
US10130736B1 (en) 2010-05-14 2018-11-20 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
US8716204B2 (en) 2010-07-27 2014-05-06 Zimmer, Inc. Synthetic synovial fluid compositions and methods for making the same
CN101934095B (zh) * 2010-08-31 2013-09-18 赵亮 一种可注射强化型磷石灰/水凝胶微囊组织工程骨及其制备方法和应用
US9446075B2 (en) * 2011-05-06 2016-09-20 Bioregenerative Sciences Compositions derived from stem cell released molecules and methods for formulation thereof
US8834928B1 (en) 2011-05-16 2014-09-16 Musculoskeletal Transplant Foundation Tissue-derived tissugenic implants, and methods of fabricating and using same
CN103796659A (zh) * 2011-07-13 2014-05-14 车比奥及戴奥斯泰有限公司 包含胶原、透明质酸衍生物和哺乳动物脐带来源干细胞的软骨细胞治疗物
US9545370B2 (en) 2012-05-08 2017-01-17 BioRegenerative Sciences, Inc. Bioactive compositions and methods for their preparation and use
KR101532556B1 (ko) 2012-09-03 2015-06-30 메디포스트(주) 간엽줄기세포의 배양 방법
CN102899287B (zh) * 2012-10-24 2013-08-21 天津和泽干细胞科技有限公司 一种诱导间充质干细胞向软骨细胞分化的方法及其在骨关节炎中的应用
ES2858648T3 (es) * 2014-01-08 2021-09-30 Samsung Life Public Welfare Foundation Células madre derivadas de la porción basal de la capa de trofoblastos coriónicos y terapia celular que comprende las mismas
EP3146973B1 (de) 2014-07-07 2020-05-06 Medipost Co., Ltd. Haarwachstumsfördernde funktion von kleinen stammzellen und verwendung davon
WO2016015007A1 (en) 2014-07-25 2016-01-28 Recellerate, Inc. Methods of treating exercise-induced pulmonary hemorrhage
KR101593318B1 (ko) 2014-08-26 2016-02-17 동국대학교 산학협력단 서방출 및 생체 적합성이 개선된 카토제닌-키토산 복합체 입자 및 이의 이용
CA2986702C (en) 2015-05-21 2023-04-04 David Wang Modified demineralized cortical bone fibers
JP6800984B2 (ja) * 2015-10-05 2020-12-16 ボード・オブ・リージエンツ，ザ・ユニバーシテイ・オブ・テキサス・システム 軟骨傷害の検出及び処置のためのマイクロ並びにナノデバイス
CN105796600B (zh) * 2016-04-28 2020-02-28 博雅干细胞科技有限公司 使用干细胞治疗骨关节炎的方法和组合物
AU2019283518A1 (en) * 2018-06-05 2021-01-14 Medipost Co., Ltd. Pharmaceutical composition comprising mesenchymal stem cells as effective ingredient for prevention or treatment of inflammatory disease
KR20200000823A (ko) 2018-06-25 2020-01-03 주식회사 씨아이에스티이엠 인간 유도 만능 줄기세포로부터 연골세포의 펠렛을 제조하는 방법 및 이의 용도
IT201800020722A1 (it) * 2018-12-21 2020-06-21 Assunta Borzacchiello Biomateriale e suo utilizzo nel trattamento di patologie polmonari
IT201900002697A1 (it) * 2019-02-25 2020-08-25 Scuola Superiore Di Studi Univ E Di Perfezionamento Santanna Materiale e sistema per il trattamento terapeutico di articolazioni
CN114173760A (zh) * 2019-08-01 2022-03-11 河唯真 用于预防或治疗关节及软骨损伤的包含透明质酸和普朗尼克的组合物
KR102156602B1 (ko) * 2019-10-17 2020-09-16 전북대학교산학협력단 miRNA-140-5p가 함유된 젤란검 하이드로겔 조성물과 이를 이용한 연골손상 치료용 조성물
CN111676190B (zh) * 2020-06-09 2022-04-22 生物岛实验室 一种干细胞向成软骨分化的诱导剂及其应用
WO2022149937A2 (ko) 2021-01-08 2022-07-14 서울대학교 산학협력단 골관절염 치료를 위한 건조된 세포 분비물 기반 치료제
JP7213500B2 (ja) 2021-03-19 2023-01-27 極東工業株式会社 固定治具
CN114569795B (zh) * 2022-03-08 2023-03-24 香港理工大学深圳研究院 一种双层骨软骨支架材料及其制备方法与应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5902741A (en) * 1986-04-18 1999-05-11 Advanced Tissue Sciences, Inc. Three-dimensional cartilage cultures
US4816437A (en) * 1987-06-01 1989-03-28 Trustees Of Boston University Methods for inducing general and localized bone apposition in-vivo
US5004681B1 (en) * 1987-11-12 2000-04-11 Biocyte Corp Preservation of fetal and neonatal hematopoietic stem and progenitor cells of the blood
US5906934A (en) * 1995-03-14 1999-05-25 Morphogen Pharmaceuticals, Inc. Mesenchymal stem cells for cartilage repair
US5842477A (en) * 1996-02-21 1998-12-01 Advanced Tissue Sciences, Inc. Method for repairing cartilage
US5919702A (en) * 1996-10-23 1999-07-06 Advanced Tissue Science, Inc. Production of cartilage tissue using cells isolated from Wharton's jelly
WO1998051317A1 (en) 1997-05-13 1998-11-19 Osiris Therapeutics, Inc. Osteoarthritis cartilage regeneration using human mesenchymal stem cells
US5985208A (en) * 1998-08-27 1999-11-16 Alliedsignal Inc. Process for debinding and sintering metal injection molded parts made with an aqueous binder
EP1099754A1 (de) 1999-11-10 2001-05-16 Universiteit Leiden Mesenchym-Stammzellen und/oder Vorlaüferzellen, ihre Isolierung und ihre Verwendung
JP4959916B2 (ja) * 2001-08-14 2012-06-27 メディポスト・カンパニー・リミテッド 関節軟骨損傷治療用組成物

Also Published As

Publication number Publication date
JP2012107026A (ja) 2012-06-07
US20090047261A1 (en) 2009-02-19
DE60208042D1 (de) 2006-01-19
JP4959916B2 (ja) 2012-06-27
KR100494265B1 (ko) 2005-06-13
EP1416944A1 (de) 2004-05-12
US7459307B2 (en) 2008-12-02
JP2005501101A (ja) 2005-01-13
JP5597817B2 (ja) 2014-10-01
DE60208042T2 (de) 2006-08-17
US20090022698A1 (en) 2009-01-22
EP1416944B1 (de) 2005-12-14
CN1543353A (zh) 2004-11-03
KR20030015160A (ko) 2003-02-20
EP1416944A4 (de) 2004-10-27
US20040151703A1 (en) 2004-08-05
WO2003015802A1 (en) 2003-02-27
US20090060885A1 (en) 2009-03-05
CN1272022C (zh) 2006-08-30

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