ATE310566T1 - 5ht2-agoniste zur behandlung des glaukoms - Google Patents

5ht2-agoniste zur behandlung des glaukoms

Info

Publication number
ATE310566T1
ATE310566T1 AT99948085T AT99948085T ATE310566T1 AT E310566 T1 ATE310566 T1 AT E310566T1 AT 99948085 T AT99948085 T AT 99948085T AT 99948085 T AT99948085 T AT 99948085T AT E310566 T1 ATE310566 T1 AT E310566T1
Authority
AT
Austria
Prior art keywords
agonits
glaucoma
treatment
Prior art date
Application number
AT99948085T
Other languages
German (de)
English (en)
Inventor
Jesse A May
Thomas R Dean
Najam A Sharif
Mark R Hellberg
Original Assignee
Alcon Mfg Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Mfg Ltd filed Critical Alcon Mfg Ltd
Application granted granted Critical
Publication of ATE310566T1 publication Critical patent/ATE310566T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT99948085T 1998-09-18 1999-09-03 5ht2-agoniste zur behandlung des glaukoms ATE310566T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10106798P 1998-09-18 1998-09-18
PCT/US1999/019888 WO2000016761A2 (fr) 1998-09-18 1999-09-03 Agonistes de 5ht2 serotoninergiques utiles pour traiter le glaucome

Publications (1)

Publication Number Publication Date
ATE310566T1 true ATE310566T1 (de) 2005-12-15

Family

ID=22282920

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99948085T ATE310566T1 (de) 1998-09-18 1999-09-03 5ht2-agoniste zur behandlung des glaukoms

Country Status (18)

Country Link
US (2) US6664286B1 (fr)
EP (1) EP1112106B1 (fr)
JP (1) JP2002526443A (fr)
KR (1) KR20010073153A (fr)
CN (1) CN1269484C (fr)
AR (1) AR020442A1 (fr)
AT (1) ATE310566T1 (fr)
AU (1) AU755119B2 (fr)
BR (1) BR9913800A (fr)
CA (1) CA2344150A1 (fr)
DE (1) DE69928542T2 (fr)
DK (1) DK1112106T3 (fr)
ES (1) ES2252978T3 (fr)
HK (1) HK1038516A1 (fr)
TR (1) TR200100754T2 (fr)
TW (1) TWI229602B (fr)
WO (1) WO2000016761A2 (fr)
ZA (1) ZA200102157B (fr)

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US7005443B1 (en) * 2000-03-17 2006-02-28 Alcon, Inc. 5-Hydroxy indazole derivatives for treating glaucoma
US6806285B1 (en) 2000-03-17 2004-10-19 Alcon, Inc. 5-Hydroxyl indole derivatives for treating glaucoma
AU2001216072A1 (en) * 2000-03-17 2001-10-03 Alcon, Inc. 6-hydroxy-indazole derivatives for treating glaucoma
US7012090B1 (en) 2000-03-17 2006-03-14 Alcon, Inc. Pyranoindoles for treating glaucoma
WO2001070686A1 (fr) * 2000-03-17 2001-09-27 Alcon, Inc. Derives de 5-hydroxy-indole destines au traitement du glaucome
US6956036B1 (en) 2000-03-17 2005-10-18 Alcon, Inc. 6-hydroxy-indazole derivatives for treating glaucoma
AU2001219185A1 (en) 2000-03-17 2001-10-03 Alcon, Inc. 2-acylaminobenzimidazole derivatives for treating glaucoma
JP2004538240A (ja) * 2000-03-31 2004-12-24 パーデュー・リサーチ・ファウンデーション ホスホラミデートおよびそのための方法
CA2447156A1 (fr) 2001-06-01 2002-12-12 Alcon, Inc. Indazoles et indoles nouveaux fusionnes et leur utilisation dans le traitement de glaucomes
CA2447479A1 (fr) 2001-06-01 2002-12-12 Alcon, Inc. Nouveaux analogues d'arylaminopropane et leur utilisation dans le traitement du glaucome
MXPA03010807A (es) 2001-06-01 2004-11-22 Alcon Inc Piranoidazoles y su uso para el tratamiento del glaucoma.
US6884816B2 (en) * 2001-08-31 2005-04-26 Alcon, Inc. Hydroxy substituted fused naphthyl-azoles and fused indeno-azoles and their use for the treatment of glaucoma
TW593302B (en) 2001-12-20 2004-06-21 Alcon Inc Novel benzodifuranimidazoline and benzofuranimidazoline derivatives and their use for the treatment of glaucoma
PL375564A1 (en) * 2002-08-30 2005-11-28 Alcon, Inc. Substituted 5-chroman-5-yl-ethylamine compounds and their use for the treatment of glaucoma
WO2004028451A2 (fr) * 2002-09-24 2004-04-08 Virginia Commonwealth University ?eta-hydroxyphenylaldylamines et utilisation de celles-ci pour traiter le glaucome
CA2506204A1 (fr) * 2002-12-13 2004-07-01 Alcon, Inc. Nouveaux analogues de benzopyranne et leur utilisation pour le traitement du glaucome
US7476687B2 (en) * 2003-11-26 2009-01-13 Alcon, Inc. Substituted furo[2,3-g]indazoles for the treatment of glaucoma
US7129257B1 (en) * 2003-12-15 2006-10-31 Alcon, Inc. Pyrazolo[3,4- e]benzoxazoles for the treatment of glaucoma
US7338972B1 (en) 2003-12-15 2008-03-04 Alcon, Inc. Substituted 1-alkylamino-1H-indazoles for the treatment of glaucoma
WO2005058911A2 (fr) * 2003-12-15 2005-06-30 Alcon, Inc. [1,4]oxazino[2,3-g]indazoles substitues pour traiter le glaucome
US20050256182A1 (en) * 2004-05-11 2005-11-17 Sutter Diane E Formulations of anti-pain agents and methods of using the same
EP2248524A3 (fr) 2004-08-25 2011-03-09 Takeda Pharmaceutical Company Limited Agents preventifs/remedes pour l'incontinence de stress et procede de selecetion de ceux-ci
US7425572B2 (en) * 2004-12-08 2008-09-16 Alcon, Inc. Use of dioxindoindazoles and dioxoloindazoles for treating glaucoma
US20060211700A1 (en) * 2005-03-21 2006-09-21 Alcon, Inc. (R)-8,9-dichloro-2,3,4,4a-tetrahydro-1H,6H-pyrazino[1,2-a]quinoxalin-5-one for controlling IOP and treating glaucoma
TW200744567A (en) * 2005-09-23 2007-12-16 Alcon Inc Phenylethylamine analogs and their use for treating glaucoma
EP2742936A1 (fr) 2006-05-16 2014-06-18 Takeda Pharmaceutical Company Limited Composé hétérocyclique condensé et son utilisation
WO2007149728A2 (fr) * 2006-06-20 2007-12-27 Alcon Research, Ltd. Dérivés d'aryl et d'hétéroaryl tétrahydrobenzazépine et leur utilisation pour traiter le glaucome
CA2704199C (fr) 2007-11-01 2016-01-19 Acucela Inc. Composes derives d'amines pour le traitement de maladies et de troubles ophtalmiques
US20100266504A1 (en) 2007-11-15 2010-10-21 Takahiro Matsumoto Condensed pyridine derivative and use thereof
US9642819B2 (en) * 2008-07-10 2017-05-09 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical Low dosage serotonin 5-HT2A receptor agonist to suppress inflammation
US8299079B2 (en) 2009-05-22 2012-10-30 Kaufman Herbert E Preparations and methods for ameliorating or reducing presbyopia
EP2510949A4 (fr) 2009-12-11 2013-11-13 Astellas Pharma Inc Agent thérapeutique pour la fibromyalgie
TW201210584A (en) 2010-08-18 2012-03-16 Alcon Res Ltd Bradykinin receptor agonists and uses thereof to treat ocular hypertension and glaucoma
GB2571696B (en) 2017-10-09 2020-05-27 Compass Pathways Ltd Large scale method for the preparation of Psilocybin and formulations of Psilocybin so produced
EP3733204A4 (fr) 2017-12-27 2021-09-15 Takeda Pharmaceutical Company Limited Agent thérapeutique pour incontinence urinaire de stress et incontinence fécale
EP3955936A1 (fr) 2019-04-17 2022-02-23 COMPASS Pathfinder Limited Traitement de la dépression et de divers autres troubles au moyen de psilocybine
WO2024010765A1 (fr) * 2022-07-05 2024-01-11 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Compositions de traitement d'états sensibles à 5-ht2 et leurs procédés d'utilisation

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EP0410384B1 (fr) 1989-07-28 1995-04-05 Nippon Oil Co. Ltd. Procédé pour la fabrication en continu d'un matériau en polyéthylène à haute résistance et à haut module
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DE69602970T2 (de) 1995-11-09 2000-01-20 Sanofi-Synthelabo, Paris 5-(phenyl)-3-(4-piperidinyl)-1,3,4-oxadiazol-2(3h)-on-derivate verwendbar als 5-ht4- oder h3-rezeptorliganden
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GB9718833D0 (en) 1997-09-04 1997-11-12 Merck Sharp & Dohme Therapeutic agents

Also Published As

Publication number Publication date
EP1112106B1 (fr) 2005-11-23
CN1317979A (zh) 2001-10-17
HK1038516A1 (en) 2002-03-22
EP1112106A2 (fr) 2001-07-04
DE69928542T2 (de) 2006-03-30
TWI229602B (en) 2005-03-21
US6664286B1 (en) 2003-12-16
WO2000016761A3 (fr) 2000-05-25
KR20010073153A (ko) 2001-07-31
WO2000016761A2 (fr) 2000-03-30
JP2002526443A (ja) 2002-08-20
AR020442A1 (es) 2002-05-15
DK1112106T3 (da) 2005-12-12
ZA200102157B (en) 2003-03-05
BR9913800A (pt) 2001-05-29
AU755119B2 (en) 2002-12-05
ES2252978T3 (es) 2006-05-16
DE69928542D1 (de) 2005-12-29
US20030203912A1 (en) 2003-10-30
AU6132699A (en) 2000-04-10
TR200100754T2 (tr) 2001-10-22
CA2344150A1 (fr) 2000-03-30
CN1269484C (zh) 2006-08-16

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