ATE304547T1 - Verfahren zur herstellung von l-ribose - Google Patents

Verfahren zur herstellung von l-ribose

Info

Publication number
ATE304547T1
ATE304547T1 AT03075945T AT03075945T ATE304547T1 AT E304547 T1 ATE304547 T1 AT E304547T1 AT 03075945 T AT03075945 T AT 03075945T AT 03075945 T AT03075945 T AT 03075945T AT E304547 T1 ATE304547 T1 AT E304547T1
Authority
AT
Austria
Prior art keywords
ribose
producing
Prior art date
Application number
AT03075945T
Other languages
German (de)
English (en)
Inventor
Chung K Chu
Yong S Choi
Jinfa Du
Original Assignee
Univ Georgia Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Georgia Res Found filed Critical Univ Georgia Res Found
Application granted granted Critical
Publication of ATE304547T1 publication Critical patent/ATE304547T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H9/00Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical
    • C07H9/02Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical the hetero ring containing only oxygen as ring hetero atoms
    • C07H9/04Cyclic acetals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06Pyrimidine radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/02Monosaccharides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT03075945T 1997-07-23 1998-07-23 Verfahren zur herstellung von l-ribose ATE304547T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US5348897P 1997-07-23 1997-07-23

Publications (1)

Publication Number Publication Date
ATE304547T1 true ATE304547T1 (de) 2005-09-15

Family

ID=21984622

Family Applications (2)

Application Number Title Priority Date Filing Date
AT03075945T ATE304547T1 (de) 1997-07-23 1998-07-23 Verfahren zur herstellung von l-ribose
AT98939087T ATE236187T1 (de) 1997-07-23 1998-07-23 Verfahren zur herstellung von 2'-fluoro-5-methyl- beta-l-arabino-furanosyluridin

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT98939087T ATE236187T1 (de) 1997-07-23 1998-07-23 Verfahren zur herstellung von 2'-fluoro-5-methyl- beta-l-arabino-furanosyluridin

Country Status (21)

Country Link
US (2) US6512107B2 (instruction)
EP (2) EP0998482B1 (instruction)
KR (1) KR100247505B1 (instruction)
CN (1) CN1113892C (instruction)
AR (1) AR009092A1 (instruction)
AT (2) ATE304547T1 (instruction)
AU (1) AU8758298A (instruction)
BR (1) BR9810804B1 (instruction)
DE (2) DE69812959T2 (instruction)
DK (1) DK1327637T3 (instruction)
ES (2) ES2249678T3 (instruction)
ID (1) ID20624A (instruction)
IL (1) IL121730A (instruction)
IN (1) IN186807B (instruction)
MY (1) MY117314A (instruction)
PT (2) PT998482E (instruction)
SA (1) SA98180771B1 (instruction)
SI (1) SI1327637T1 (instruction)
TR (1) TR199701051A3 (instruction)
TW (1) TW434252B (instruction)
WO (2) WO1999005157A1 (instruction)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW434252B (en) 1997-07-23 2001-05-16 Univ Georgia Res Found Process for the preparation of 2'-fluoro-5-methyl-β-L-arabino-furanosyluridine
KR100449618B1 (ko) * 1998-03-27 2004-11-16 부광약품 주식회사 2'-플루오로-5-메틸-β-L-아라비노푸라노실유리딘의 제조방법
US6462191B1 (en) * 2000-07-13 2002-10-08 Air Products And Chemicals, Inc. Synthesis of 2-deoxy-2-fluoro-arabinose derivatives
MXPA03008870A (es) * 2001-03-30 2004-01-29 Triangle Pharmaceuticals Inc Proceso para la preparacion de nucleosidos de 2¦halo-(beta)-l-arabinofuranosilo.
KR100487992B1 (ko) * 2001-10-25 2005-05-09 부광약품 주식회사 2'-플루오로-5-메틸-β-엘-아라비노푸라노실유리딘의 황유도체
AU2002360697B2 (en) * 2001-12-20 2009-04-23 Beth Israel Deaconess Medical Center Treatment of EBV and KHSV infection and associated abnormal cellular proliferation
KR100976778B1 (ko) 2003-04-17 2010-08-18 부광약품 주식회사 1-(2'-플루오로-베타-엘-아라비노푸라노실)티민의 황 유도체를 유효 활성 성분으로 하는 b형 간염 바이러스 치료제
BRPI0515279A (pt) 2004-09-14 2008-07-15 Pharmasset Inc preparação de ribofuranosil pirimidinas e purinas 2'fluoro-2'-alquil- substituìdas ou outras opcionalmente substituìdas e seus derivados
CN103735560A (zh) * 2005-06-07 2014-04-23 耶鲁大学 使用克来夫定和替比夫定治疗癌症和其它病症或疾病状态的方法
CN102066369B (zh) 2007-06-18 2013-05-29 广东东阳光药业有限公司 一种溴苯基-取代的噻唑二氢嘧啶
GB0907551D0 (en) 2009-05-01 2009-06-10 Univ Dundee Treatment or prophylaxis of proliferative conditions
JP2021512953A (ja) 2018-02-02 2021-05-20 メイベリックス オンコロジー インコーポレイテッド ゲムシタビンモノホスフェートの小分子薬物コンジュゲート
CN109320564B (zh) * 2018-10-26 2022-05-31 浙江晟格生物科技有限公司 一种l-来苏糖的制备工艺
CN109467541A (zh) * 2018-11-17 2019-03-15 扬州工业职业技术学院 一种绿色合成克拉夫定药物中间体的方法
CN109467583A (zh) * 2018-11-17 2019-03-15 扬州工业职业技术学院 一种克拉夫定的绿色合成工艺

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3714473A1 (de) * 1987-04-30 1988-11-10 Basf Ag Kontinuierliches verfahren zur epimerisierung von zuckern, insbesondere von d-arabinose zu d-ribose
EP0400064B1 (en) 1988-02-09 1993-04-21 Uop Solid catalysts for continuous interconversion of epimeric aldoses and aldose analogs
DE4002727A1 (de) * 1990-01-31 1991-08-01 Bayer Ag Mischungen aus waessrigen polymerdispersionen
US5587362A (en) 1994-01-28 1996-12-24 Univ. Of Ga Research Foundation L-nucleosides
US5808040A (en) 1995-01-30 1998-09-15 Yale University L-nucleosides incorporated into polymeric structure for stabilization of oligonucleotides
TW434252B (en) 1997-07-23 2001-05-16 Univ Georgia Res Found Process for the preparation of 2'-fluoro-5-methyl-β-L-arabino-furanosyluridine

Also Published As

Publication number Publication date
TR199701051A2 (xx) 1999-03-22
IN186807B (instruction) 2001-11-10
KR100247505B1 (ko) 2000-03-15
CN1113892C (zh) 2003-07-09
BR9810804B1 (pt) 2012-01-10
EP0998482A1 (en) 2000-05-10
ID20624A (id) 1999-01-28
TR199701051A3 (tr) 1999-03-22
US6894159B2 (en) 2005-05-17
AR009092A1 (es) 2000-03-08
PT998482E (pt) 2003-08-29
TW434252B (en) 2001-05-16
IL121730A (en) 2005-03-20
DE69831619T2 (de) 2006-06-14
WO1999005157A1 (en) 1999-02-04
AU8758298A (en) 1999-02-16
SI1327637T1 (sl) 2005-12-31
DE69831619D1 (de) 2005-10-20
KR19990013297A (ko) 1999-02-25
EP1327637A1 (en) 2003-07-16
DK1327637T3 (da) 2006-01-16
DE69812959D1 (de) 2003-05-08
SA98180771B1 (ar) 2006-10-29
ES2249678T3 (es) 2006-04-01
US20030139593A1 (en) 2003-07-24
WO1999005158A1 (en) 1999-02-04
ATE236187T1 (de) 2003-04-15
US20020062018A1 (en) 2002-05-23
BR9810804A (pt) 2000-09-12
CN1206012A (zh) 1999-01-27
EP1327637B1 (en) 2005-09-14
MY117314A (en) 2004-06-30
EP0998482B1 (en) 2003-04-02
IL121730A0 (en) 1998-02-22
US6512107B2 (en) 2003-01-28
PT1327637E (pt) 2005-11-30
DE69812959T2 (de) 2004-03-04
ES2195370T3 (es) 2003-12-01

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