ATE301648T1 - Verfahren zur herstellung von 4- oxytetrahydropyran-2-onen - Google Patents
Verfahren zur herstellung von 4- oxytetrahydropyran-2-onenInfo
- Publication number
- ATE301648T1 ATE301648T1 AT03710622T AT03710622T ATE301648T1 AT E301648 T1 ATE301648 T1 AT E301648T1 AT 03710622 T AT03710622 T AT 03710622T AT 03710622 T AT03710622 T AT 03710622T AT E301648 T1 ATE301648 T1 AT E301648T1
- Authority
- AT
- Austria
- Prior art keywords
- ones
- oxytetrahydropyran
- producing
- reaction
- reagent
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/30—Oxygen atoms, e.g. delta-lactones
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyrane Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SI200200086A SI21187A (sl) | 2002-03-26 | 2002-03-26 | Postopek za pripravo 4-oksitetrahidropiran-2-onov |
| PCT/SI2003/000009 WO2003080591A1 (en) | 2002-03-26 | 2003-03-17 | Process for the preparation of 4-oxytetrahydropyran-2-ones |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE301648T1 true ATE301648T1 (de) | 2005-08-15 |
Family
ID=28450345
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03710622T ATE301648T1 (de) | 2002-03-26 | 2003-03-17 | Verfahren zur herstellung von 4- oxytetrahydropyran-2-onen |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US7094912B2 (de) |
| EP (1) | EP1487814B1 (de) |
| JP (1) | JP2005523303A (de) |
| KR (1) | KR20040106306A (de) |
| CN (1) | CN1281596C (de) |
| AT (1) | ATE301648T1 (de) |
| AU (1) | AU2003214791A1 (de) |
| DE (1) | DE60301267T2 (de) |
| EA (1) | EA007012B1 (de) |
| HR (1) | HRP20040885B1 (de) |
| PL (1) | PL208279B1 (de) |
| SI (1) | SI21187A (de) |
| WO (1) | WO2003080591A1 (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2239543B1 (es) * | 2004-03-15 | 2006-08-01 | Ercros Industrial, S.A. | Procedimiento para la obtencion de simvastatina. |
| WO2007096753A2 (en) * | 2006-02-21 | 2007-08-30 | Cadila Healthcare Limited | Process for preparing highly pure simvastatin |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU548996B2 (en) | 1980-02-04 | 1986-01-09 | Merck & Co., Inc. | Tetrahydro-2h-pyran-2-one derivatives |
| EP0137445B1 (de) | 1983-10-11 | 1990-01-03 | Merck & Co. Inc. | Verfahren zur C-Methylierung von 2-Methylbutyraten |
| US4820850A (en) | 1987-07-10 | 1989-04-11 | Merck & Co., Inc. | Process for α-C-alkylation of the 8-acyl group on mevinolin and analogs thereof |
| US4894466A (en) * | 1988-02-29 | 1990-01-16 | Merck & Co., Inc. | Intermediates and processes for β-6-hydroxymethyl HMG-CoA reductable inhibitors |
| FI893004A (fi) | 1988-06-29 | 1989-12-30 | Merck & Co Inc | 5-oxygenerade hmg-coa-reduktas -inhibitorer. |
| CA2036962C (en) | 1990-02-26 | 1998-09-15 | Ann E. Decamp | Process for the desilylation of a 4-silyloxy-tetrahydro-pyran-2-one |
| US5393893A (en) | 1993-11-08 | 1995-02-28 | Apotex, Inc. | Process for producing simvastatin and analogs thereof |
| US5763653A (en) | 1997-03-13 | 1998-06-09 | Ranbaxy Laboratories, Ltd. | Key intermediates in the manufacture of simvastatin |
| US5763646A (en) | 1997-03-13 | 1998-06-09 | Ranbaxy Laboratories, Ltd. | Process for manufacturing simvastatin from lovastatin or mevinolinic acid |
| DE69813538T2 (de) | 1997-01-28 | 2004-04-01 | Plus Chemicals B.V. | Verfahren zur herstellung von halbsynthetischen statinen vianeue zwischenprodukte |
| SI20159A (sl) * | 1999-02-04 | 2000-08-31 | LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. | Nov postopek za odstranitev sililoksi zaščitne skupine iz 4-sililoksi tetrahidro-piran-2-on-ov |
| AU2000234636A1 (en) | 2000-03-30 | 2001-10-08 | Cheil Jedang Corporation | A process for producing simvastatin |
| US6833461B2 (en) * | 2001-02-27 | 2004-12-21 | Chong Kun Dang Pharmaceutical Corp. | Process for preparing simvastatin |
-
2002
- 2002-03-26 SI SI200200086A patent/SI21187A/sl not_active IP Right Cessation
-
2003
- 2003-03-17 AT AT03710622T patent/ATE301648T1/de not_active IP Right Cessation
- 2003-03-17 US US10/509,611 patent/US7094912B2/en not_active Expired - Fee Related
- 2003-03-17 EP EP03710622A patent/EP1487814B1/de not_active Expired - Lifetime
- 2003-03-17 WO PCT/SI2003/000009 patent/WO2003080591A1/en active IP Right Grant
- 2003-03-17 PL PL372360A patent/PL208279B1/pl unknown
- 2003-03-17 KR KR10-2004-7015123A patent/KR20040106306A/ko not_active Application Discontinuation
- 2003-03-17 EA EA200401253A patent/EA007012B1/ru not_active IP Right Cessation
- 2003-03-17 JP JP2003578346A patent/JP2005523303A/ja active Pending
- 2003-03-17 CN CNB038089475A patent/CN1281596C/zh not_active Expired - Fee Related
- 2003-03-17 AU AU2003214791A patent/AU2003214791A1/en not_active Abandoned
- 2003-03-17 DE DE60301267T patent/DE60301267T2/de not_active Expired - Lifetime
-
2004
- 2004-09-24 HR HRP20040885AA patent/HRP20040885B1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DE60301267D1 (de) | 2005-09-15 |
| EP1487814A1 (de) | 2004-12-22 |
| PL372360A1 (en) | 2005-07-25 |
| HRP20040885B1 (en) | 2012-09-30 |
| CN1281596C (zh) | 2006-10-25 |
| EP1487814B1 (de) | 2005-08-10 |
| HRP20040885A2 (en) | 2005-04-30 |
| SI21187A (sl) | 2003-10-31 |
| US7094912B2 (en) | 2006-08-22 |
| EA007012B1 (ru) | 2006-06-30 |
| WO2003080591A1 (en) | 2003-10-02 |
| US20050182263A1 (en) | 2005-08-18 |
| AU2003214791A1 (en) | 2003-10-08 |
| JP2005523303A (ja) | 2005-08-04 |
| KR20040106306A (ko) | 2004-12-17 |
| PL208279B1 (pl) | 2011-04-29 |
| EA200401253A1 (ru) | 2005-04-28 |
| CN1646517A (zh) | 2005-07-27 |
| DE60301267T2 (de) | 2006-06-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |