ATE288499T1 - Die verwendung von modularen oligonukleotiden als sonden oder primern in auf nukleinsaure basierenden tests - Google Patents
Die verwendung von modularen oligonukleotiden als sonden oder primern in auf nukleinsaure basierenden testsInfo
- Publication number
- ATE288499T1 ATE288499T1 AT97942121T AT97942121T ATE288499T1 AT E288499 T1 ATE288499 T1 AT E288499T1 AT 97942121 T AT97942121 T AT 97942121T AT 97942121 T AT97942121 T AT 97942121T AT E288499 T1 ATE288499 T1 AT E288499T1
- Authority
- AT
- Austria
- Prior art keywords
- primers
- probe
- modular
- acid based
- methods
- Prior art date
Links
- 108091034117 Oligonucleotide Proteins 0.000 title abstract 4
- JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methyl [5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate Polymers Cc1cn(C2CC(OP(O)(=O)OCC3OC(CC3OP(O)(=O)OCC3OC(CC3O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c3nc(N)[nH]c4=O)C(COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3CO)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cc(C)c(=O)[nH]c3=O)n3cc(C)c(=O)[nH]c3=O)n3ccc(N)nc3=O)n3cc(C)c(=O)[nH]c3=O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)O2)c(=O)[nH]c1=O JLCPHMBAVCMARE-UHFFFAOYSA-N 0.000 title abstract 2
- 239000002253 acid Substances 0.000 title 1
- 238000000034 method Methods 0.000 abstract 5
- 230000000295 complement effect Effects 0.000 abstract 2
- 238000002955 isolation Methods 0.000 abstract 2
- 108020004707 nucleic acids Proteins 0.000 abstract 2
- 150000007523 nucleic acids Chemical class 0.000 abstract 2
- 102000039446 nucleic acids Human genes 0.000 abstract 2
- 239000002773 nucleotide Substances 0.000 abstract 2
- 125000003729 nucleotide group Chemical group 0.000 abstract 2
- 238000001514 detection method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
- C12Q1/706—Specific hybridization probes for hepatitis
- C12Q1/707—Specific hybridization probes for hepatitis non-A, non-B Hepatitis, excluding hepatitis D
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6832—Enhancement of hybridisation reaction
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Communicable Diseases (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Virology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Seeds, Soups, And Other Foods (AREA)
- Semiconductor Lasers (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9620075.3A GB9620075D0 (en) | 1996-09-26 | 1996-09-26 | Method |
| PCT/GB1997/002629 WO1998013522A1 (en) | 1996-09-26 | 1997-09-26 | The use of modular oligonucleotides as probes or primers in nucleic acid based assay |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE288499T1 true ATE288499T1 (de) | 2005-02-15 |
Family
ID=10800518
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97942121T ATE288499T1 (de) | 1996-09-26 | 1997-09-26 | Die verwendung von modularen oligonukleotiden als sonden oder primern in auf nukleinsaure basierenden tests |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6482592B1 (enExample) |
| EP (1) | EP0928342B1 (enExample) |
| JP (1) | JP2001501470A (enExample) |
| AT (1) | ATE288499T1 (enExample) |
| AU (1) | AU743820B2 (enExample) |
| CA (1) | CA2266749C (enExample) |
| DE (1) | DE69732419T2 (enExample) |
| ES (1) | ES2234031T3 (enExample) |
| GB (1) | GB9620075D0 (enExample) |
| WO (1) | WO1998013522A1 (enExample) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9620075D0 (en) | 1996-09-26 | 1996-11-13 | Dynal As | Method |
| US5888778A (en) * | 1997-06-16 | 1999-03-30 | Exact Laboratories, Inc. | High-throughput screening method for identification of genetic mutations or disease-causing microorganisms using segmented primers |
| CA2247545C (en) * | 1998-09-15 | 2008-12-30 | Dynal As | Method of isolation of primer extension products with modular oligonucleotides |
| AU773108B2 (en) * | 1998-09-15 | 2004-05-13 | Dynal Asa | Method of isolation primer extension products with modular oligonucleotides |
| US20010031467A1 (en) * | 1999-12-10 | 2001-10-18 | Johannes Dapprich | Method for selectively isolating a nucleic acid |
| ATE510012T1 (de) * | 2001-03-15 | 2011-06-15 | Univ Aix Marseille Ii | Herstellung von kalibratoren und ihre verwendung zur quantifizierung von besonderen nukleotidsequenzen |
| DE602004021185D1 (de) * | 2003-06-27 | 2009-07-02 | Nanosphere Inc | Auf bio-barcodes beruhender nachweis von zielanalyten |
| US20050095627A1 (en) * | 2003-09-03 | 2005-05-05 | The Salk Institute For Biological Studies | Multiple antigen detection assays and reagents |
| US20060040300A1 (en) * | 2004-08-09 | 2006-02-23 | Generation Biotech, Llc | Method for nucleic acid isolation and amplification |
| US9109256B2 (en) | 2004-10-27 | 2015-08-18 | Esoterix Genetic Laboratories, Llc | Method for monitoring disease progression or recurrence |
| WO2007044071A2 (en) | 2005-04-21 | 2007-04-19 | Exact Sciences Corporation | Analysis of heterogeneous nucleic acid samples |
| US20090263798A1 (en) * | 2006-05-15 | 2009-10-22 | Generation Biotech, Llc | Method For Identification Of Novel Physical Linkage Of Genomic Sequences |
| EP1903117A1 (en) * | 2006-09-22 | 2008-03-26 | Veterinärmedizinische Universität Wien | Methods for the detection of mutations by means of primers that hybridize contiguously |
| US8790916B2 (en) | 2009-05-14 | 2014-07-29 | Genestream, Inc. | Microfluidic method and system for isolating particles from biological fluid |
| US8747084B2 (en) | 2010-07-21 | 2014-06-10 | Aperia Technologies, Inc. | Peristaltic pump |
| EP2809784A4 (en) * | 2012-01-31 | 2015-07-15 | Advanced Liquid Logic Inc | AMPLIFICATION SPREADERS AND PROBES FOR DETECTING HIV-1 |
| US9862995B2 (en) * | 2012-03-13 | 2018-01-09 | Abhijit Ajit Patel | Measurement of nucleic acid variants using highly-multiplexed error-suppressed deep sequencing |
| PL2828103T3 (pl) | 2012-03-20 | 2017-09-29 | Aperia Technologies | System pompowania opon |
| US10144254B2 (en) | 2013-03-12 | 2018-12-04 | Aperia Technologies, Inc. | Tire inflation system |
| US9604157B2 (en) | 2013-03-12 | 2017-03-28 | Aperia Technologies, Inc. | Pump with water management |
| US11453258B2 (en) | 2013-03-12 | 2022-09-27 | Aperia Technologies, Inc. | System for tire inflation |
| ITUA20163413A1 (it) * | 2016-05-13 | 2017-11-13 | Fondazione St Italiano Tecnologia | Reazione di amplificazione di acidi nucleici con primer cooperativi. |
| WO2018048885A1 (en) | 2016-09-06 | 2018-03-15 | Aperia Technologies, Inc. | System for tire inflation |
| US10406869B2 (en) | 2017-11-10 | 2019-09-10 | Aperia Technologies, Inc. | Inflation system |
| US11642920B2 (en) | 2018-11-27 | 2023-05-09 | Aperia Technologies, Inc. | Hub-integrated inflation system |
| US12442364B2 (en) | 2023-12-11 | 2025-10-14 | Aperia Technologies, Inc. | Two-stage pump and method of operation |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5149625A (en) | 1987-08-11 | 1992-09-22 | President And Fellows Of Harvard College | Multiplex analysis of DNA |
| US5030557A (en) | 1987-11-24 | 1991-07-09 | Ml Technology Venture | Means and method for enhancing nucleic acid hybridization |
| US4988617A (en) * | 1988-03-25 | 1991-01-29 | California Institute Of Technology | Method of detecting a nucleotide change in nucleic acids |
| JPH03504199A (ja) * | 1988-05-10 | 1991-09-19 | イー・アイ・デユポン・ド・ネモアース・アンド・コンパニー | 迅速な核酸検出法 |
| EP0426843B1 (en) * | 1989-05-24 | 1995-09-13 | Amoco Corporation | Nucleic acid probes for the detection of neisseria gonorrhoeae |
| FR2663040B1 (fr) * | 1990-06-11 | 1995-09-15 | Bio Merieux | Procede de detection d'une sequence nucleotidique selon la technique d'hybridation sandwich. |
| JPH0484899A (ja) * | 1990-07-26 | 1992-03-18 | Tosoh Corp | 核酸測定法 |
| US5627032A (en) * | 1990-12-24 | 1997-05-06 | Ulanovsky; Levy | Composite primers for nucleic acids |
| US5428145A (en) | 1991-08-09 | 1995-06-27 | Immuno Japan, Inc. | Non-A, non-B, hepatitis virus genome, polynucleotides, polypeptides, antigen, antibody and detection systems |
| US5387510A (en) | 1991-10-02 | 1995-02-07 | Eastman Kodak Company | Detection of amplified nucleic acid using secondary capture oligonucleotides and test kit |
| GB9207598D0 (en) | 1992-04-03 | 1992-05-20 | Dynal As | Method of sequencing double stranded dna |
| JP3408564B2 (ja) * | 1992-04-30 | 2003-05-19 | メディカル リサーチ カウンスル | 結核菌中のイソニアジド抵抗性の迅速検出 |
| US5547843A (en) * | 1992-07-17 | 1996-08-20 | Associated Universities, Inc. | Method for promoting specific alignment of short oligonucleotides on nucleic acids |
| JP3454847B2 (ja) * | 1992-08-26 | 2003-10-06 | 株式会社東芝 | ハイブリダイゼーション法 |
| CA2119701A1 (en) * | 1993-04-16 | 1994-10-17 | Colleen M. Nycz | Nucleic acid assay procedure |
| JP3746083B2 (ja) * | 1993-05-28 | 2006-02-15 | 日本製粉株式会社 | 隣接する２種の核酸プローブを用いたｒｎａの検出方法 |
| CA2170264A1 (en) | 1993-09-10 | 1995-03-16 | Michael W. Konrad | Optical detection of position of oligonucleotides on large dna molecules |
| AU702436B2 (en) * | 1994-10-21 | 1999-02-18 | Innogenetics N.V. | New sequences of hepatitis C virus genotypes and their use as prophylactic, therapeutic and diagnostic agents |
| US5731153A (en) * | 1996-08-26 | 1998-03-24 | The Regents Of The University Of California | Identification of random nucleic acid sequence aberrations using dual capture probes which hybridize to different chromosome regions |
| US5908745A (en) * | 1996-01-16 | 1999-06-01 | University Of Chicago | Use of continuous/contiguous stacking hybridization as a diagnostic tool |
| GB9620075D0 (en) | 1996-09-26 | 1996-11-13 | Dynal As | Method |
| US6124092A (en) | 1996-10-04 | 2000-09-26 | The Perkin-Elmer Corporation | Multiplex polynucleotide capture methods and compositions |
| CA2247545C (en) * | 1998-09-15 | 2008-12-30 | Dynal As | Method of isolation of primer extension products with modular oligonucleotides |
-
1996
- 1996-09-26 GB GBGB9620075.3A patent/GB9620075D0/en active Pending
-
1997
- 1997-09-26 AT AT97942121T patent/ATE288499T1/de not_active IP Right Cessation
- 1997-09-26 ES ES97942121T patent/ES2234031T3/es not_active Expired - Lifetime
- 1997-09-26 EP EP97942121A patent/EP0928342B1/en not_active Expired - Lifetime
- 1997-09-26 JP JP10515411A patent/JP2001501470A/ja not_active Ceased
- 1997-09-26 AU AU43917/97A patent/AU743820B2/en not_active Ceased
- 1997-09-26 CA CA002266749A patent/CA2266749C/en not_active Expired - Fee Related
- 1997-09-26 DE DE69732419T patent/DE69732419T2/de not_active Expired - Lifetime
- 1997-09-26 WO PCT/GB1997/002629 patent/WO1998013522A1/en not_active Ceased
-
1998
- 1998-09-15 US US09/153,242 patent/US6482592B1/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AU743820B2 (en) | 2002-02-07 |
| JP2001501470A (ja) | 2001-02-06 |
| US6482592B1 (en) | 2002-11-19 |
| DE69732419T2 (de) | 2006-04-06 |
| CA2266749A1 (en) | 1998-04-02 |
| AU4391797A (en) | 1998-04-17 |
| WO1998013522A1 (en) | 1998-04-02 |
| DE69732419D1 (de) | 2005-03-10 |
| EP0928342A1 (en) | 1999-07-14 |
| EP0928342B1 (en) | 2005-02-02 |
| CA2266749C (en) | 2009-11-10 |
| ES2234031T3 (es) | 2005-06-16 |
| GB9620075D0 (en) | 1996-11-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 0928342 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |