ATE285241T1 - Pharmazeutische zubereitungen, enthaltend salze von hyaluronsäure und lokalanästhetika - Google Patents
Pharmazeutische zubereitungen, enthaltend salze von hyaluronsäure und lokalanästhetikaInfo
- Publication number
- ATE285241T1 ATE285241T1 AT97943093T AT97943093T ATE285241T1 AT E285241 T1 ATE285241 T1 AT E285241T1 AT 97943093 T AT97943093 T AT 97943093T AT 97943093 T AT97943093 T AT 97943093T AT E285241 T1 ATE285241 T1 AT E285241T1
- Authority
- AT
- Austria
- Prior art keywords
- hyaluronic acid
- pharmaceutical preparations
- preparations containing
- local anesthetics
- containing salts
- Prior art date
Links
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical class CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 title abstract 2
- 229920002674 hyaluronan Polymers 0.000 title abstract 2
- 229960003160 hyaluronic acid Drugs 0.000 title abstract 2
- 239000000825 pharmaceutical preparation Substances 0.000 title abstract 2
- 239000003589 local anesthetic agent Chemical class 0.000 title 1
- 229960005015 local anesthetics Drugs 0.000 title 1
- CNBGNNVCVSKAQZ-UHFFFAOYSA-N benzydamine Chemical compound C12=CC=CC=C2C(OCCCN(C)C)=NN1CC1=CC=CC=C1 CNBGNNVCVSKAQZ-UHFFFAOYSA-N 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- LEBVLXFERQHONN-UHFFFAOYSA-N 1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide Chemical compound CCCCN1CCCCC1C(=O)NC1=C(C)C=CC=C1C LEBVLXFERQHONN-UHFFFAOYSA-N 0.000 abstract 1
- 125000001931 aliphatic group Chemical group 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 230000003444 anaesthetic effect Effects 0.000 abstract 1
- 229960000333 benzydamine Drugs 0.000 abstract 1
- 229960003150 bupivacaine Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/728—Hyaluronic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A61K31/416—1,2-Diazoles condensed with carbocyclic ring systems, e.g. indazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
- A61P23/02—Local anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Anesthesiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Cosmetics (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Materials For Medical Uses (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT96PD000254A IT1287967B1 (it) | 1996-10-17 | 1996-10-17 | Preparazioni farmaceutiche per uso anestetico locale |
| PCT/IB1997/001288 WO1998017285A1 (en) | 1996-10-17 | 1997-10-17 | Pharmaceutical preparations comprised of salts of hyaluronic acid with local anaesthetics |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE285241T1 true ATE285241T1 (de) | 2005-01-15 |
Family
ID=11391550
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97943093T ATE285241T1 (de) | 1996-10-17 | 1997-10-17 | Pharmazeutische zubereitungen, enthaltend salze von hyaluronsäure und lokalanästhetika |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US6224857B1 (de) |
| EP (1) | EP0956026B1 (de) |
| JP (1) | JP4334620B2 (de) |
| KR (1) | KR20000049281A (de) |
| AT (1) | ATE285241T1 (de) |
| AU (1) | AU712927B2 (de) |
| BR (1) | BR9713486A (de) |
| CA (1) | CA2268967C (de) |
| DE (1) | DE69732049T2 (de) |
| ES (1) | ES2235254T3 (de) |
| IT (1) | IT1287967B1 (de) |
| TR (1) | TR199900860T2 (de) |
| WO (1) | WO1998017285A1 (de) |
Families Citing this family (74)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7338433B2 (en) | 2002-08-13 | 2008-03-04 | Allergan, Inc. | Remotely adjustable gastric banding method |
| BR0306183A (pt) | 2002-08-28 | 2004-10-19 | Inamed Medical Products Corp | Dispositivo de enfaixamento gástrico resistente à fadiga |
| DE10246340A1 (de) * | 2002-10-04 | 2004-04-29 | Wohlrab, David, Dr. | Kombinationspräparat aus Hyaluronsäure und mindestens einem Lokalanästhetikum und dessen Verwendung |
| US7238677B2 (en) * | 2003-03-28 | 2007-07-03 | Kimberly-Clark Worldwide, Inc. | Prevention of urogenital infections |
| FR2861734B1 (fr) | 2003-04-10 | 2006-04-14 | Corneal Ind | Reticulation de polysaccharides de faible et forte masse moleculaire; preparation d'hydrogels monophasiques injectables; polysaccharides et hydrogels obtenus |
| JP4672302B2 (ja) * | 2003-08-05 | 2011-04-20 | 天藤製薬株式会社 | 安定な局所麻酔組成物 |
| US20050095219A1 (en) * | 2003-10-29 | 2005-05-05 | Shu-Ping Yang | Compositions for promoting vaginal cell proliferation and maturation |
| MXPA06008256A (es) | 2004-01-23 | 2007-02-20 | Allergan Inc | Banda gastrica ajustable de una sola pieza que se asegura de manera liberable. |
| ATE444045T1 (de) | 2004-03-08 | 2009-10-15 | Allergan Medical S A | Verschlusssystem für röhrenförmige organe |
| WO2005094257A2 (en) | 2004-03-18 | 2005-10-13 | Inamed Medical Products Corporation | Apparatus and method for volume adjustment of intragastric balloons |
| US8251888B2 (en) | 2005-04-13 | 2012-08-28 | Mitchell Steven Roslin | Artificial gastric valve |
| US20070110788A1 (en) * | 2005-11-14 | 2007-05-17 | Hissong James B | Injectable formulation capable of forming a drug-releasing device |
| US7798954B2 (en) | 2006-01-04 | 2010-09-21 | Allergan, Inc. | Hydraulic gastric band with collapsible reservoir |
| US8043206B2 (en) | 2006-01-04 | 2011-10-25 | Allergan, Inc. | Self-regulating gastric band with pressure data processing |
| US7959943B2 (en) * | 2006-05-10 | 2011-06-14 | Medtronics Xomed, Inc. | Solvating system and sealant for medical use in the middle or inner ear |
| US7976873B2 (en) * | 2006-05-10 | 2011-07-12 | Medtronic Xomed, Inc. | Extracellular polysaccharide solvating system for treatment of bacterial ear conditions |
| US7993675B2 (en) | 2006-05-10 | 2011-08-09 | Medtronic Xomed, Inc. | Solvating system and sealant for medical use in the sinuses and nasal passages |
| US20070264296A1 (en) * | 2006-05-10 | 2007-11-15 | Myntti Matthew F | Biofilm extracellular polysachharide solvating system |
| US8088095B2 (en) * | 2007-02-08 | 2012-01-03 | Medtronic Xomed, Inc. | Polymeric sealant for medical use |
| EP2152743A2 (de) * | 2007-05-23 | 2010-02-17 | Allergan, Inc. | Quervernetztes collagen und anwendungen davon |
| US8318695B2 (en) * | 2007-07-30 | 2012-11-27 | Allergan, Inc. | Tunably crosslinked polysaccharide compositions |
| US8697044B2 (en) * | 2007-10-09 | 2014-04-15 | Allergan, Inc. | Crossed-linked hyaluronic acid and collagen and uses thereof |
| EP3498299A1 (de) | 2007-11-16 | 2019-06-19 | Aclaris Therapeutics, Inc. | Zusammensetzungen und verfahren zur behandlung von purpura |
| US8394784B2 (en) * | 2007-11-30 | 2013-03-12 | Allergan, Inc. | Polysaccharide gel formulation having multi-stage bioactive agent delivery |
| US20090143348A1 (en) * | 2007-11-30 | 2009-06-04 | Ahmet Tezel | Polysaccharide gel compositions and methods for sustained delivery of drugs |
| US8394782B2 (en) * | 2007-11-30 | 2013-03-12 | Allergan, Inc. | Polysaccharide gel formulation having increased longevity |
| US8784790B2 (en) | 2008-06-12 | 2014-07-22 | Medtronic Xomed, Inc. | Method for treating chronic wounds with an extracellular polymeric substance solvating system |
| US8450475B2 (en) * | 2008-08-04 | 2013-05-28 | Allergan, Inc. | Hyaluronic acid-based gels including lidocaine |
| JP5722217B2 (ja) | 2008-09-02 | 2015-05-20 | アラーガン・ホールディングス・フランス・ソシエテ・パール・アクシオン・サンプリフィエＡｌｌｅｒｇａｎ Ｈｏｌｄｉｎｇｓ Ｆｒａｎｃｅ Ｓ．Ａ．Ｓ． | ヒアルロン酸および／またはその誘導体の糸、その作製方法、ならびにその使用 |
| US20100305397A1 (en) * | 2008-10-06 | 2010-12-02 | Allergan Medical Sarl | Hydraulic-mechanical gastric band |
| US20100086576A1 (en) * | 2008-10-06 | 2010-04-08 | Myntti Matthew F | Antimicrobial composition and methods of making and using same |
| WO2010042493A1 (en) | 2008-10-06 | 2010-04-15 | Allergan, Inc. | Mechanical gastric band with cushions |
| US20100185049A1 (en) | 2008-10-22 | 2010-07-22 | Allergan, Inc. | Dome and screw valves for remotely adjustable gastric banding systems |
| US8390326B2 (en) * | 2009-05-05 | 2013-03-05 | William Marsh Rice University | Method for fabrication of a semiconductor element and structure thereof |
| WO2011049958A2 (en) | 2009-10-21 | 2011-04-28 | Otonomy, Inc. | Modulation of gel temperature of poloxamer-containing formulations |
| US20110171286A1 (en) * | 2010-01-13 | 2011-07-14 | Allergan, Inc. | Hyaluronic acid compositions for dermatological use |
| US20110172180A1 (en) | 2010-01-13 | 2011-07-14 | Allergan Industrie. Sas | Heat stable hyaluronic acid compositions for dermatological use |
| US20110171311A1 (en) * | 2010-01-13 | 2011-07-14 | Allergan Industrie, Sas | Stable hydrogel compositions including additives |
| US9114188B2 (en) | 2010-01-13 | 2015-08-25 | Allergan, Industrie, S.A.S. | Stable hydrogel compositions including additives |
| US8758221B2 (en) | 2010-02-24 | 2014-06-24 | Apollo Endosurgery, Inc. | Source reservoir with potential energy for remotely adjustable gastric banding system |
| US8840541B2 (en) * | 2010-02-25 | 2014-09-23 | Apollo Endosurgery, Inc. | Pressure sensing gastric banding system |
| CA2792729C (en) * | 2010-03-12 | 2016-06-28 | Allergan Industrie, Sas | Fluid compositions for improving skin conditions |
| HUE030138T2 (en) | 2010-03-22 | 2017-04-28 | Allergan Inc | Polysaccharide and protein-polysaccharide cross-linked hydrogels for soft tissue augmentation |
| US9028394B2 (en) | 2010-04-29 | 2015-05-12 | Apollo Endosurgery, Inc. | Self-adjusting mechanical gastric band |
| US20110270024A1 (en) | 2010-04-29 | 2011-11-03 | Allergan, Inc. | Self-adjusting gastric band having various compliant components |
| US9044298B2 (en) | 2010-04-29 | 2015-06-02 | Apollo Endosurgery, Inc. | Self-adjusting gastric band |
| US20110270025A1 (en) | 2010-04-30 | 2011-11-03 | Allergan, Inc. | Remotely powered remotely adjustable gastric band system |
| US8517915B2 (en) | 2010-06-10 | 2013-08-27 | Allergan, Inc. | Remotely adjustable gastric banding system |
| US8883139B2 (en) | 2010-08-19 | 2014-11-11 | Allergan Inc. | Compositions and soft tissue replacement methods |
| US9005605B2 (en) | 2010-08-19 | 2015-04-14 | Allergan, Inc. | Compositions and soft tissue replacement methods |
| US8697057B2 (en) | 2010-08-19 | 2014-04-15 | Allergan, Inc. | Compositions and soft tissue replacement methods |
| US8889123B2 (en) | 2010-08-19 | 2014-11-18 | Allergan, Inc. | Compositions and soft tissue replacement methods |
| US20120059216A1 (en) | 2010-09-07 | 2012-03-08 | Allergan, Inc. | Remotely adjustable gastric banding system |
| US8961393B2 (en) | 2010-11-15 | 2015-02-24 | Apollo Endosurgery, Inc. | Gastric band devices and drive systems |
| US10653133B2 (en) | 2011-05-10 | 2020-05-19 | Next Science IP Holdings Pty Ltd | Antimicrobial solid and methods of making and using same |
| US20130096081A1 (en) | 2011-06-03 | 2013-04-18 | Allergan, Inc. | Dermal filler compositions |
| US9393263B2 (en) | 2011-06-03 | 2016-07-19 | Allergan, Inc. | Dermal filler compositions including antioxidants |
| US9408797B2 (en) | 2011-06-03 | 2016-08-09 | Allergan, Inc. | Dermal filler compositions for fine line treatment |
| AU2012262047A1 (en) | 2011-06-03 | 2014-01-16 | Allergan, Inc. | Dermal filler compositions including antioxidants |
| US20130244943A1 (en) | 2011-09-06 | 2013-09-19 | Allergan, Inc. | Hyaluronic acid-collagen matrices for dermal filling and volumizing applications |
| US9662422B2 (en) | 2011-09-06 | 2017-05-30 | Allergan, Inc. | Crosslinked hyaluronic acid-collagen gels for improving tissue graft viability and soft tissue augmentation |
| EP2581079B1 (de) | 2011-10-11 | 2016-12-07 | BioPolymer GmbH & Co. KG | Kombination aus Hyaluronsäure und Prilocain |
| US8876694B2 (en) | 2011-12-07 | 2014-11-04 | Apollo Endosurgery, Inc. | Tube connector with a guiding tip |
| US8961394B2 (en) | 2011-12-20 | 2015-02-24 | Apollo Endosurgery, Inc. | Self-sealing fluid joint for use with a gastric band |
| EP2985027B1 (de) | 2014-08-16 | 2021-03-31 | Church & Dwight Co., Inc. | Nasenheilmittel enthaltend ein gemisch von hyaluronsäuren und salzlösung |
| EP2985019B1 (de) | 2014-08-16 | 2021-10-20 | Church & Dwight Co., Inc. | Nasale Zusammensetzung mit antiviralen Eigenschaften |
| WO2016051219A1 (en) | 2014-09-30 | 2016-04-07 | Allergan Industrie, Sas | Stable hydrogel compositions including additives |
| WO2016128783A1 (en) | 2015-02-09 | 2016-08-18 | Allergan Industrie Sas | Compositions and methods for improving skin appearance |
| EP3653232A1 (de) | 2015-02-13 | 2020-05-20 | Allergan Industrie, SAS | Implantate zur formung, verstärkung oder korrektur von gesichtszügen wie etwa dem kinn |
| CN106187864B (zh) * | 2016-07-11 | 2018-11-23 | 江苏天和制药有限公司 | 一种由盐酸布比卡因制备高纯度布比卡因碱的方法 |
| IT201800001890A1 (it) * | 2018-01-25 | 2019-07-25 | Fidia Farm Spa | Composizioni farmaceutiche per il trattamento del dolore postoperatorio |
| EP3977881B1 (de) | 2020-09-04 | 2024-06-19 | Bert Raf Celis | Sportbekleidung für das fahrradfahren und zugehörige kühlverfahren |
| JP2024519426A (ja) * | 2020-09-29 | 2024-05-14 | ジロパ・インコーポレイテッド | 疼痛の緩和及び麻痺のための組成物及び方法 |
| KR102762718B1 (ko) * | 2022-02-23 | 2025-02-06 | 주식회사 스카이테라퓨틱스 | 고분자 히알루론산의 구조체, 이의 제조방법 및 이를 포함하는 화장료 조성물 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1229075B (it) * | 1985-04-05 | 1991-07-17 | Fidia Farmaceutici | Medicamenti per uso topico, ottenuti tramite l'impiego dell'acido ialuronico |
| IN163192B (de) * | 1983-10-11 | 1988-08-20 | Fidia Spa | |
| US4851521A (en) | 1985-07-08 | 1989-07-25 | Fidia, S.P.A. | Esters of hyaluronic acid |
| IT1247175B (it) | 1991-04-19 | 1994-12-12 | Fidia Spa | Procedimento per la purificazione di acido ialuronico e frazione di acido ialuronico puro per uso oftalmico. |
| HUP9700322A3 (en) * | 1995-06-09 | 2001-03-28 | Euro Celtique Sa | Formulations and methods for providing prolonged local anesthesia |
-
1996
- 1996-10-17 IT IT96PD000254A patent/IT1287967B1/it active IP Right Grant
-
1997
- 1997-10-17 KR KR1019990703392A patent/KR20000049281A/ko not_active Ceased
- 1997-10-17 EP EP97943093A patent/EP0956026B1/de not_active Expired - Lifetime
- 1997-10-17 DE DE69732049T patent/DE69732049T2/de not_active Expired - Lifetime
- 1997-10-17 BR BR9713486-4A patent/BR9713486A/pt not_active Application Discontinuation
- 1997-10-17 CA CA002268967A patent/CA2268967C/en not_active Expired - Lifetime
- 1997-10-17 US US09/284,668 patent/US6224857B1/en not_active Expired - Lifetime
- 1997-10-17 AU AU44700/97A patent/AU712927B2/en not_active Expired
- 1997-10-17 WO PCT/IB1997/001288 patent/WO1998017285A1/en not_active Ceased
- 1997-10-17 AT AT97943093T patent/ATE285241T1/de active
- 1997-10-17 ES ES97943093T patent/ES2235254T3/es not_active Expired - Lifetime
- 1997-10-17 JP JP51916298A patent/JP4334620B2/ja not_active Expired - Fee Related
- 1997-10-17 TR TR1999/00860T patent/TR199900860T2/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE69732049D1 (de) | 2005-01-27 |
| AU712927B2 (en) | 1999-11-18 |
| JP2001503042A (ja) | 2001-03-06 |
| TR199900860T2 (xx) | 1999-06-21 |
| ITPD960254A1 (it) | 1998-04-17 |
| KR20000049281A (ko) | 2000-07-25 |
| AU4470097A (en) | 1998-05-15 |
| WO1998017285A1 (en) | 1998-04-30 |
| EP0956026A1 (de) | 1999-11-17 |
| EP0956026B1 (de) | 2004-12-22 |
| HK1023518A1 (en) | 2000-09-15 |
| CA2268967A1 (en) | 1998-04-30 |
| US6224857B1 (en) | 2001-05-01 |
| DE69732049T2 (de) | 2006-03-02 |
| CA2268967C (en) | 2003-02-04 |
| JP4334620B2 (ja) | 2009-09-30 |
| IT1287967B1 (it) | 1998-09-10 |
| BR9713486A (pt) | 2000-04-11 |
| ES2235254T3 (es) | 2005-07-01 |
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