ATE284679T1 - Implantierbare verabreichungsvorrichtung mit einer selbstjustierenden ausgangsöffnung - Google Patents

Implantierbare verabreichungsvorrichtung mit einer selbstjustierenden ausgangsöffnung

Info

Publication number
ATE284679T1
ATE284679T1 AT98911539T AT98911539T ATE284679T1 AT E284679 T1 ATE284679 T1 AT E284679T1 AT 98911539 T AT98911539 T AT 98911539T AT 98911539 T AT98911539 T AT 98911539T AT E284679 T1 ATE284679 T1 AT E284679T1
Authority
AT
Austria
Prior art keywords
self
exit opening
administration device
implantable administration
adjusting exit
Prior art date
Application number
AT98911539T
Other languages
English (en)
Inventor
Juan C Gumucio
Keith E Dionne
James E Brown
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Application granted granted Critical
Publication of ATE284679T1 publication Critical patent/ATE284679T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medicinal Preparation (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Bidet-Like Cleaning Device And Other Flush Toilet Accessories (AREA)
  • Refuse Collection And Transfer (AREA)
  • Paper (AREA)
  • Coating Apparatus (AREA)
AT98911539T 1997-03-24 1998-03-10 Implantierbare verabreichungsvorrichtung mit einer selbstjustierenden ausgangsöffnung ATE284679T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3560797P 1997-03-24 1997-03-24
PCT/US1998/004637 WO1998042317A2 (en) 1997-03-24 1998-03-10 Implantable delivery device with self adjustable exit port

Publications (1)

Publication Number Publication Date
ATE284679T1 true ATE284679T1 (de) 2005-01-15

Family

ID=21883714

Family Applications (2)

Application Number Title Priority Date Filing Date
AT98911539T ATE284679T1 (de) 1997-03-24 1998-03-10 Implantierbare verabreichungsvorrichtung mit einer selbstjustierenden ausgangsöffnung
AT03075936T ATE363897T1 (de) 1997-03-24 1998-03-10 Implantierbare verabreichungsvorrichtung mit einer selbstjustierenden ausgangsöffnung

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT03075936T ATE363897T1 (de) 1997-03-24 1998-03-10 Implantierbare verabreichungsvorrichtung mit einer selbstjustierenden ausgangsöffnung

Country Status (19)

Country Link
US (2) US5997527A (de)
EP (1) EP0969820B1 (de)
JP (1) JP2002513414A (de)
KR (1) KR100572188B1 (de)
CN (2) CN1290590C (de)
AR (1) AR010407A1 (de)
AT (2) ATE284679T1 (de)
AU (1) AU738417B2 (de)
CA (1) CA2284929C (de)
CO (1) CO5021220A1 (de)
DE (2) DE69828157T2 (de)
ES (1) ES2232940T3 (de)
IL (1) IL132041A0 (de)
MY (1) MY123359A (de)
NZ (1) NZ338024A (de)
PT (1) PT969820E (de)
TW (1) TW369419B (de)
WO (1) WO1998042317A2 (de)
ZA (1) ZA981610B (de)

Families Citing this family (90)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY125870A (en) * 1997-07-25 2006-08-30 Alza Corp Osmotic delivery system flow modulator apparatus and method
ATE234603T1 (de) * 1998-12-31 2003-04-15 Alza Corp Osmotisches verabreichungsystem mit raumsparenden kolben
US7919109B2 (en) 1999-02-08 2011-04-05 Intarcia Therapeutics, Inc. Stable non-aqueous single phase viscous vehicles and formulations utilizing such vehicles
US7258869B1 (en) * 1999-02-08 2007-08-21 Alza Corporation Stable non-aqueous single phase viscous vehicles and formulations utilizing such vehicle
DE60023361T2 (de) 1999-12-21 2006-04-27 Alza Corp., Mountain View Ventil für osmotische vorrichtungen
DK1246662T3 (da) * 1999-12-27 2006-01-16 Alza Corp Osmotisk system til levering af gavnligt middel
US6464688B1 (en) 2000-02-15 2002-10-15 Microsolutions, Inc. Osmotic pump delivery system with flexible drug compartment
US6454759B2 (en) * 2000-02-28 2002-09-24 The Regents Of The University Of California Microfabricated injectable drug delivery system
US6375972B1 (en) * 2000-04-26 2002-04-23 Control Delivery Systems, Inc. Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof
US6796972B1 (en) 2000-07-14 2004-09-28 Edwards Lifesciences Llc Catheter anchoring balloon structure with irrigation
US6464662B1 (en) 2000-07-26 2002-10-15 Image-Guided Neurologics, Inc. Drug delivery and catheter systems, apparatus and processes
US6561479B1 (en) * 2000-08-23 2003-05-13 Micron Technology, Inc. Small scale actuators and methods for their formation and use
US6605055B1 (en) 2000-09-13 2003-08-12 Cardiofocus, Inc. Balloon catheter with irrigation sheath
AU2007202144B2 (en) * 2000-11-29 2009-04-23 Durect Corporation Devices and methods for controlled delivery from a drug delivery device
JP4248236B2 (ja) * 2000-11-29 2009-04-02 デュレクト コーポレイション 薬物送達装置からの送達を制御するための装置および方法
WO2002056863A2 (en) * 2000-12-29 2002-07-25 Bausch & Lomb Incorporated Sustained release drug delivery devices
DE60137542D1 (de) 2001-01-03 2009-03-12 Bausch & Lomb Wirkstoffabgabevorrichtungen mit verzögerter freisetzung mehrere stoffe enthaltend
CA2433032C (en) * 2001-01-03 2008-11-25 Bausch & Lomb Incorporated Sustained release drug delivery devices with coated drug cores
US6805207B2 (en) * 2001-01-23 2004-10-19 Black & Decker Inc. Housing with functional overmold
US6632217B2 (en) 2001-04-19 2003-10-14 Microsolutions, Inc. Implantable osmotic pump
GB2374905B (en) * 2001-04-27 2004-09-15 Reckitt Benckiser Uk Ltd Aerosol delivery system
US7163688B2 (en) * 2001-06-22 2007-01-16 Alza Corporation Osmotic implant with membrane and membrane retention means
US7648496B2 (en) * 2001-09-17 2010-01-19 Durect Corporation Device and method for accurate delivery of an active agent
US8871241B2 (en) 2002-05-07 2014-10-28 Psivida Us, Inc. Injectable sustained release delivery devices
CN1668279A (zh) * 2002-06-17 2005-09-14 阿尔萨公司 具有包含分散在液体载体中的渗透物质的早期零级推动力动力系统的渗透递送体系
US6939556B2 (en) * 2002-06-26 2005-09-06 Alza Corporation Minimally compliant, volume efficient piston for osmotic drug delivery systems
US20060009739A1 (en) * 2002-09-06 2006-01-12 Durect Corporation Implantable flow regulator with failsafe mode and reserve drug supply
US7014636B2 (en) * 2002-11-21 2006-03-21 Alza Corporation Osmotic delivery device having a two-way valve and a dynamically self-adjusting flow channel
US7731947B2 (en) * 2003-11-17 2010-06-08 Intarcia Therapeutics, Inc. Composition and dosage form comprising an interferon particle formulation and suspending vehicle
CA2508124A1 (en) * 2002-12-19 2004-07-08 Alza Corporation Stable, non-aqueous, single-phase gels and formulations thereof for delivery from an implantable device
CA2520610A1 (en) * 2003-03-31 2004-10-21 Alza Corporation Osmotic pump with means for dissipating internal pressure
AR043810A1 (es) * 2003-03-31 2005-08-17 Alza Corp Sistema osmotico de administracion y metodo para disminuir los tiempos de llegada al regimen de funcionamiento en los sistemas osmoticos de administracion
DE602004015755D1 (de) 2003-03-31 2008-09-25 Alza Corp Nicht wässrige einphasige visköse vehikel und formulierungen die diese vehikel verwenden
US7678103B2 (en) 2003-06-12 2010-03-16 Cordis Corporation Orifice device for delivering drugs at low fluid flow rates
US6976983B2 (en) 2003-06-12 2005-12-20 Cordis Corporation Implantable device for delivering drugs using orifice mechanism capable of low fluid flow rates
US8109922B2 (en) 2003-06-12 2012-02-07 Cordis Corporation Orifice device having multiple channels and multiple layers for drug delivery
US8491571B2 (en) 2003-06-12 2013-07-23 Cordis Corporation Orifice device having multiple channels with varying flow rates for drug delivery
US7108762B2 (en) 2003-06-12 2006-09-19 Cordis Corporation Method for manufacturing an orifice mechanism capable of low fluid flow rates
US7211076B2 (en) 2003-06-12 2007-05-01 Cordis Corporation Medical device for fluid delivery having low fluid flow rate
AU2004277980A1 (en) 2003-09-30 2005-04-14 Alza Corporation Osmotically driven active agent delivery device providing an ascending release profile
JP2007526792A (ja) * 2003-11-06 2007-09-20 アルザ・コーポレーシヨン 移植可能な浸透ポンプと一緒の使用のためのモジュール型の吸入速度低下器
US20050175701A1 (en) * 2004-02-10 2005-08-11 Alza Corporation Capillary moderator for osmotic delivery system
US20050266087A1 (en) * 2004-05-25 2005-12-01 Gunjan Junnarkar Formulations having increased stability during transition from hydrophobic vehicle to hydrophilic medium
US7731715B2 (en) 2004-12-10 2010-06-08 Edwards Lifesciences Corporation Ablative treatment of atrial fibrillation via the coronary sinus
US7655254B2 (en) * 2005-02-03 2010-02-02 Intarcia Therapeutics, Inc. Implantable device for continuous delivery of interferon
WO2006083761A2 (en) 2005-02-03 2006-08-10 Alza Corporation Solvent/polymer solutions as suspension vehicles
US11246913B2 (en) 2005-02-03 2022-02-15 Intarcia Therapeutics, Inc. Suspension formulation comprising an insulinotropic peptide
US7959938B2 (en) * 2005-03-15 2011-06-14 Intarcia Therapeutics, Inc. Polyoxaester suspending vehicles for use with implantable delivery systems
US20070027105A1 (en) 2005-07-26 2007-02-01 Alza Corporation Peroxide removal from drug delivery vehicle
CN101351148B (zh) * 2005-12-28 2010-09-08 奥林巴斯医疗株式会社 被检体内观察系统
WO2007140416A2 (en) 2006-05-30 2007-12-06 Intarcia Therapeutics, Inc. Two-piece, internal-channel osmotic delivery system flow modulator
PT2359808E (pt) 2006-08-09 2013-08-28 Intarcia Therapeutics Inc Sistemas de entrega osmótica e montagens de pistão
US8617143B2 (en) * 2006-12-07 2013-12-31 The Regents Of The University Of California Therapeutic agent delivery systems and devices
ES2402172T3 (es) 2007-04-23 2013-04-29 Intarcia Therapeutics, Inc Formulación en suspensión de péptidos insulinotrópicos y usos de los mismos
WO2009102467A2 (en) 2008-02-13 2009-08-20 Intarcia Therapeutics, Inc. Devices, formulations, and methods for delivery of multiple beneficial agents
US20090259217A1 (en) * 2008-04-09 2009-10-15 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Methods and systems associated with delivery of one or more agents to an individual
US20090259112A1 (en) * 2008-04-09 2009-10-15 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Sensors
US8028743B2 (en) * 2008-04-17 2011-10-04 Hewlett-Packard Development Company, L.P. Passive cooling in response to ambient environmental properties
ES2604590T3 (es) * 2008-09-10 2017-03-07 Sandoz Ag Cápsula con elemento de bloqueo soluble
CN102281865B (zh) * 2008-10-15 2017-04-05 精达制药公司 高浓缩药物颗粒、制剂、混悬剂及其应用
EP3735944A1 (de) * 2009-09-28 2020-11-11 Intarcia Therapeutics, Inc. Schnelle initiierung und/oder beendigung der verabreichung substantiell stabiler arzneimittel
US8038650B2 (en) * 2010-02-22 2011-10-18 Microsert Ltd. Slow release liquid drug delivery device
US20120208755A1 (en) 2011-02-16 2012-08-16 Intarcia Therapeutics, Inc. Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers
US8979885B2 (en) 2012-02-24 2015-03-17 Elwha Llc Devices, systems, and methods to control stomach volume
CN104001261A (zh) * 2013-02-27 2014-08-27 重庆市北碚区精神卫生中心 一种皮下给药装置
US10137287B2 (en) 2013-03-05 2018-11-27 Taris Biomedical Llc Drug delivery devices and methods for controlled drug release through device orifice
EP2968120B1 (de) * 2013-03-15 2026-01-14 TARIS Biomedical LLC Wirkstofffreisetzungsvorrichtungen und verfahren zur wirkstofffreisetzung
US9889085B1 (en) 2014-09-30 2018-02-13 Intarcia Therapeutics, Inc. Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c
KR102650751B1 (ko) 2015-06-03 2024-03-22 인타르시아 세라퓨틱스 인코포레이티드 임플란트 배치 및 제거 시스템들
PL3370705T3 (pl) 2015-11-05 2022-08-01 The General Hospital Corporation Dooponowe dostarczanie sekwencji kwasów nukleinowych do kodowania abcd1 w leczeniu adrenomieloneuropatii
CN109310743A (zh) 2016-05-16 2019-02-05 因塔西亚制药公司 胰高血糖素受体选择性多肽及其使用方法
USD860451S1 (en) 2016-06-02 2019-09-17 Intarcia Therapeutics, Inc. Implant removal tool
USD840030S1 (en) 2016-06-02 2019-02-05 Intarcia Therapeutics, Inc. Implant placement guide
US10406336B2 (en) 2016-08-03 2019-09-10 Neil S. Davey Adjustable rate drug delivery implantable device
EP4635569A3 (de) 2016-10-20 2025-12-31 Peptron, Inc. Verfahren zur abgabe eines neuroprotektiven polypeptids an das zentrale nervensystem
AU2018206539A1 (en) 2017-01-03 2019-07-18 Intarcia Therapeutics, Inc. Methods comprising continuous administration of a GLP-1 receptor agonist and co-administration of a drug
US11020575B2 (en) * 2017-02-01 2021-06-01 Taris Biomedical Llc In vivo drug delivery devices and methods for drug delivery
WO2018165462A1 (en) 2017-03-08 2018-09-13 Intarcia Therapeutics, Inc Apparatus and methods for administration of a nauseogenic compound from a drug delivery device
EP3630263A4 (de) * 2017-05-29 2021-03-17 Bionaut Labs Ltd. Auslösung einer nutzlastfreigabe aus miniaturisierten vorrichtungen
CN108339189A (zh) * 2018-02-08 2018-07-31 孙玉荣 一种口腔给药治疗装置
USD933219S1 (en) 2018-07-13 2021-10-12 Intarcia Therapeutics, Inc. Implant removal tool and assembly
IL282079B2 (en) 2018-10-11 2025-09-01 Intarcia Therapeutics Inc Human amylin analog polypeptides and methods of use
WO2020089016A1 (en) * 2018-10-30 2020-05-07 F. Hoffmann-La Roche Ag Implantation needle and kit
CN110613872A (zh) * 2019-10-31 2019-12-27 厦门大学嘉庚学院 一种防止血液凝固的留置针辅助装置及其工作方法
EP4090353A4 (de) 2020-01-13 2023-08-09 Durect Corporation Arzneimittelabgabesysteme mit verzögerter freisetzung mit reduzierten verunreinigungen und verwandte verfahren
CN112370645A (zh) * 2020-11-25 2021-02-19 珠海市人民医院 一种皮肤涂药瓶及使用方法
JP2024503402A (ja) 2021-01-12 2024-01-25 デュレクト コーポレーション 徐放性薬物送達システム及び関連の方法
JPWO2023181996A1 (de) * 2022-03-25 2023-09-28
WO2025160155A1 (en) 2024-01-22 2025-07-31 The Broad Institute, Inc. Epigenetic targeting of prion diseases
EP4684816A1 (de) * 2024-07-23 2026-01-28 Manta MedTech LLC Implantierbare vorrichtung mit einstellbarer dosis mit drucksensor zur überwachung der kolbenverschiebung

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3732865A (en) * 1971-01-13 1973-05-15 Alza Corp Osmotic dispenser
US3987790A (en) * 1975-10-01 1976-10-26 Alza Corporation Osmotically driven fluid dispenser
GB2048710B (en) * 1979-05-07 1983-03-09 Alza Corp Osmotically driven fluid dispenser
US4455143A (en) * 1982-03-22 1984-06-19 Alza Corporation Osmotic device for dispensing two different medications
US4781714A (en) * 1983-11-02 1988-11-01 Alza Corporation Dispenser for delivering thermo-responsive composition
US5034229A (en) * 1988-12-13 1991-07-23 Alza Corporation Dispenser for increasing feed conversion of hog
KR0171224B1 (ko) * 1990-01-24 1999-02-01 에드워드 엘. 맨델 내부 압력조절 수단을 포함하는 전달 시스템
US5122128A (en) * 1990-03-15 1992-06-16 Alza Corporation Orifice insert for a ruminal bolus
US5861166A (en) * 1991-03-12 1999-01-19 Alza Corporation Delivery device providing beneficial agent stability
MX9205850A (es) * 1991-10-10 1993-06-01 Alza Corp Dispositivos de surtido osmotico de farmaco con materiales de pared hidrofobicos
US5308348A (en) * 1992-02-18 1994-05-03 Alza Corporation Delivery devices with pulsatile effect
US5456679A (en) * 1992-02-18 1995-10-10 Alza Corporation Delivery devices with pulsatile effect
US5221278A (en) * 1992-03-12 1993-06-22 Alza Corporation Osmotically driven delivery device with expandable orifice for pulsatile delivery effect
US5639477A (en) * 1993-06-23 1997-06-17 Alza Corporation Ruminal drug delivery device
PL189137B1 (pl) * 1996-02-02 2005-06-30 Alza Corp Implantowane urządzenie do dostarczania substancji aktywnej

Also Published As

Publication number Publication date
CN1504242A (zh) 2004-06-16
AU6547298A (en) 1998-10-20
EP0969820B1 (de) 2004-12-15
DE69828157T2 (de) 2005-12-22
AR010407A1 (es) 2000-06-07
EP0969820A2 (de) 2000-01-12
HK1067077A1 (en) 2005-04-01
KR20010005657A (ko) 2001-01-15
TW369419B (en) 1999-09-11
MY123359A (en) 2006-05-31
CN1290590C (zh) 2006-12-20
DE69837894T2 (de) 2008-01-31
DE69837894D1 (de) 2007-07-19
CN1251036A (zh) 2000-04-19
DE69828157D1 (de) 2005-01-20
IL132041A0 (en) 2001-03-19
HK1025049A1 (en) 2000-11-03
CN1139411C (zh) 2004-02-25
ATE363897T1 (de) 2007-06-15
CA2284929A1 (en) 1998-10-01
PT969820E (pt) 2005-02-28
ZA981610B (en) 1999-08-26
US5997527A (en) 1999-12-07
ES2232940T3 (es) 2005-06-01
WO1998042317A3 (en) 1998-12-30
AU738417B2 (en) 2001-09-20
NZ338024A (en) 2001-06-29
KR100572188B1 (ko) 2006-04-18
CA2284929C (en) 2006-12-19
US6217906B1 (en) 2001-04-17
CO5021220A1 (es) 2001-03-27
JP2002513414A (ja) 2002-05-08
WO1998042317A2 (en) 1998-10-01

Similar Documents

Publication Publication Date Title
ATE363897T1 (de) Implantierbare verabreichungsvorrichtung mit einer selbstjustierenden ausgangsöffnung
DE69507955D1 (de) Prosthetische verschlusseinrichtung
DE69519911D1 (de) Prothesenverankerungsvorrichtung
DE69233344D1 (de) Implantierbare Einlassöffnung
NO996106L (no) 4"-substituert-9-deokso-9A-AZA-9A-Homoerytromycin A-derivater
DE59803755D1 (de) Intraluminale implantationsvorrichtung
DE69720881D1 (de) Katheteranordnung
DE69515387D1 (de) Verriegelungseinrichtung mit einer Riegelfunktion
ZA981935B (en) Tissue with a moisture barrier
HUP0100104A3 (en) A closing device
DE19882269T1 (de) Automatisches Übergehen zwischen ACPI-C3- und -C2-Zuständen
DE69711509D1 (de) Einzugsarretiervorrichtung in einer Erntemaschine
BR9603689A (pt) Dispositivo médico possuindo um revestimento lúbrico sobre o mesmo
DE69418445D1 (de) MOS-Bauelement mit einer drainseitigen Kanalimplantation
DE69530750D1 (de) Verschlussverbindung
DK0818964T3 (da) Doseringsstift
IT1293648B1 (it) Otturatore a vitone perfezionato
ZA989883B (en) A closing device
DE59606017D1 (de) Schliessvorrichtung
DE59802232D1 (de) Telefongerät mit einer haltesicherung
IT1277752B1 (it) Doccia con dispositivo anticalcare a spilli
FIU960240U0 (fi) Lukituslaite
FR2744479B1 (fr) Verrou a onglet
IT1295757B1 (it) Otturatore a vitone perfezionato
DK0969820T3 (da) Implanterbar udleveringsanordning med en selvjusterende udgangsport

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 0969820

Country of ref document: EP

REN Ceased due to non-payment of the annual fee