ATE281161T1 - Heilmittel und vorbeugende mittel die cyclopentenonverbindungen als wirksamen stoff enthalten - Google Patents
Heilmittel und vorbeugende mittel die cyclopentenonverbindungen als wirksamen stoff enthaltenInfo
- Publication number
- ATE281161T1 ATE281161T1 AT99937010T AT99937010T ATE281161T1 AT E281161 T1 ATE281161 T1 AT E281161T1 AT 99937010 T AT99937010 T AT 99937010T AT 99937010 T AT99937010 T AT 99937010T AT E281161 T1 ATE281161 T1 AT E281161T1
- Authority
- AT
- Austria
- Prior art keywords
- diseases
- need
- remedies
- regulation
- active substance
- Prior art date
Links
- BZKFMUIJRXWWQK-UHFFFAOYSA-N Cyclopentenone Chemical class O=C1CCC=C1 BZKFMUIJRXWWQK-UHFFFAOYSA-N 0.000 title abstract 2
- 230000003449 preventive effect Effects 0.000 title abstract 2
- 239000013543 active substance Substances 0.000 title 1
- 239000003795 chemical substances by application Substances 0.000 title 1
- 201000010099 disease Diseases 0.000 abstract 6
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 6
- 125000001931 aliphatic group Chemical group 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 102000002812 Heat-Shock Proteins Human genes 0.000 abstract 1
- 108010004889 Heat-Shock Proteins Proteins 0.000 abstract 1
- 206010061218 Inflammation Diseases 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 230000033228 biological regulation Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000002538 fungal effect Effects 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 1
- 230000007365 immunoregulation Effects 0.000 abstract 1
- 230000006698 induction Effects 0.000 abstract 1
- 230000004054 inflammatory process Effects 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
- 230000024155 regulation of cell adhesion Effects 0.000 abstract 1
- 230000024060 regulation of tumor necrosis factor production Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
- A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/013—Esters of alcohols having the esterified hydroxy group bound to a carbon atom of a ring other than a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/10—Systems containing only non-condensed rings with a five-membered ring the ring being unsaturated
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Emergency Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP23165998 | 1998-08-18 | ||
| PCT/JP1999/004323 WO2000010560A1 (fr) | 1998-08-18 | 1999-08-10 | Moyens de traitement ou de prevention contenant des composes de cyclopentenone comme principe actif |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE281161T1 true ATE281161T1 (de) | 2004-11-15 |
Family
ID=16926974
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99937010T ATE281161T1 (de) | 1998-08-18 | 1999-08-10 | Heilmittel und vorbeugende mittel die cyclopentenonverbindungen als wirksamen stoff enthalten |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6548543B1 (de) |
| EP (1) | EP1112742B1 (de) |
| KR (1) | KR20010072356A (de) |
| CN (1) | CN1250211C (de) |
| AT (1) | ATE281161T1 (de) |
| AU (1) | AU5195799A (de) |
| DE (1) | DE69921670T2 (de) |
| ES (1) | ES2228078T3 (de) |
| TW (1) | TWI246919B (de) |
| WO (1) | WO2000010560A1 (de) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000048586A1 (en) * | 1999-02-19 | 2000-08-24 | Takara Shuzo Co., Ltd. | Remedies |
| US20030032625A1 (en) * | 2001-03-29 | 2003-02-13 | Topo Target Aps | Succinimide and maleimide derivatives and their use as topoisomerase II catalytic inhibitors |
| ES2477884T3 (es) | 2008-08-19 | 2014-07-18 | Xenoport, Inc. | Profármacos de hidrogenofumarato de metilo, composiciones farmacéuticas de los mismos y procedimientos de uso |
| GB0910856D0 (en) * | 2009-06-23 | 2009-08-05 | Univ Aston | Antimicrobial agent |
| US20140348915A9 (en) | 2012-08-22 | 2014-11-27 | Xenoport, Inc. | Oral Dosage Forms of Methyl Hydrogen Fumarate and Prodrugs Thereof |
| EP2887934A1 (de) | 2012-08-22 | 2015-07-01 | XenoPort, Inc. | Verfahren zur verabreichung von monomethylfumarat und prodrugs davon mit verringerten nebenwirkungen |
| ES2481990B1 (es) * | 2012-12-31 | 2015-05-08 | Ciber De Enfermedades Respiratorias (Ciberes) | Compuestos ciclopentenonas, procedimiento de obtención y su uso en la preparación de un medicamento útil para el tratamiento de enfermedades inflamatorias que cursan con procesos apoptóticos y fibróticos celulares. |
| EA201890239A3 (ru) | 2013-03-14 | 2018-10-31 | Алкермес Фарма Айэрлэнд Лимитед | Фумараты как пролекарства и их применение при лечении различных заболеваний |
| US8669281B1 (en) | 2013-03-14 | 2014-03-11 | Alkermes Pharma Ireland Limited | Prodrugs of fumarates and their use in treating various diseases |
| WO2014160633A1 (en) | 2013-03-24 | 2014-10-02 | Xenoport, Inc. | Pharmaceutical compositions of dimethyl fumarate |
| US9302977B2 (en) | 2013-06-07 | 2016-04-05 | Xenoport, Inc. | Method of making monomethyl fumarate |
| WO2014205392A1 (en) | 2013-06-21 | 2014-12-24 | Xenoport, Inc. | Cocrystals of dimethyl fumarate |
| JP2016534133A (ja) | 2013-09-06 | 2016-11-04 | ゼノポート，インコーポレイティド | （ｎ，ｎ−ジエチルカルバモイル）メチル メチル（２ｅ）ブト−２−エン−１，４−ジオエートの結晶形態、その合成方法及び使用 |
| NZ723269A (en) | 2014-02-24 | 2017-04-28 | Alkermes Pharma Ireland Ltd | Sulfonamide and sulfinamide prodrugs of fumarates and their use in treating various diseases |
| US9999672B2 (en) | 2014-03-24 | 2018-06-19 | Xenoport, Inc. | Pharmaceutical compositions of fumaric acid esters |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0768163B2 (ja) | 1989-03-17 | 1995-07-26 | 財団法人野口研究所 | シクロペンテノン誘導体の製法 |
| IT1289250B1 (it) | 1996-12-13 | 1998-09-29 | Consiglio Nazionale Ricerche | Impiego di 2 ciclopenten 1-one e suoi derivati come inibitori del fattore nf-kb |
| KR100582159B1 (ko) | 1996-09-27 | 2006-05-24 | 다카라 바이오 가부시키가이샤 | 사이클로펜테논, 이의 제조방법 및 용도 |
| AU730766B2 (en) | 1997-03-11 | 2001-03-15 | Takara Bio Inc. | Cyclopentenone derivative |
| JP3639601B2 (ja) * | 1997-06-30 | 2005-04-20 | タカラバイオ株式会社 | シクロペンテノン誘導体 |
-
1999
- 1999-08-10 DE DE69921670T patent/DE69921670T2/de not_active Expired - Fee Related
- 1999-08-10 EP EP99937010A patent/EP1112742B1/de not_active Expired - Lifetime
- 1999-08-10 AT AT99937010T patent/ATE281161T1/de not_active IP Right Cessation
- 1999-08-10 AU AU51957/99A patent/AU5195799A/en not_active Abandoned
- 1999-08-10 ES ES99937010T patent/ES2228078T3/es not_active Expired - Lifetime
- 1999-08-10 US US09/763,244 patent/US6548543B1/en not_active Expired - Fee Related
- 1999-08-10 CN CNB998123102A patent/CN1250211C/zh not_active Expired - Fee Related
- 1999-08-10 WO PCT/JP1999/004323 patent/WO2000010560A1/ja not_active Ceased
- 1999-08-10 KR KR1020017001696A patent/KR20010072356A/ko not_active Ceased
- 1999-08-13 TW TW088113895A patent/TWI246919B/zh active
Also Published As
| Publication number | Publication date |
|---|---|
| US6548543B1 (en) | 2003-04-15 |
| EP1112742A1 (de) | 2001-07-04 |
| CN1250211C (zh) | 2006-04-12 |
| EP1112742A4 (de) | 2001-11-14 |
| DE69921670D1 (de) | 2004-12-09 |
| AU5195799A (en) | 2000-03-14 |
| DE69921670T2 (de) | 2005-11-03 |
| KR20010072356A (ko) | 2001-07-31 |
| CN1323204A (zh) | 2001-11-21 |
| ES2228078T3 (es) | 2005-04-01 |
| WO2000010560A1 (fr) | 2000-03-02 |
| TWI246919B (en) | 2006-01-11 |
| EP1112742B1 (de) | 2004-11-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |