ATE280756T1 - Substituierte benzolverbindungen als antiproliferative mittel - Google Patents

Substituierte benzolverbindungen als antiproliferative mittel

Info

Publication number
ATE280756T1
ATE280756T1 AT98939384T AT98939384T ATE280756T1 AT E280756 T1 ATE280756 T1 AT E280756T1 AT 98939384 T AT98939384 T AT 98939384T AT 98939384 T AT98939384 T AT 98939384T AT E280756 T1 ATE280756 T1 AT E280756T1
Authority
AT
Austria
Prior art keywords
agents
substituted benzene
antiproliferative agents
compositions
benzene compounds
Prior art date
Application number
AT98939384T
Other languages
German (de)
English (en)
Inventor
Julio Cesar Medina
David Louis Clark
John A Flygare
Terry J Rosen
Bei Shan
Original Assignee
Tularik Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tularik Inc filed Critical Tularik Inc
Application granted granted Critical
Publication of ATE280756T1 publication Critical patent/ATE280756T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C311/21—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT98939384T 1997-08-22 1998-08-13 Substituierte benzolverbindungen als antiproliferative mittel ATE280756T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/917,025 US6284923B1 (en) 1997-08-22 1997-08-22 Substituted benzene compounds as antiproliferative and cholesterol lowering action
PCT/US1998/016781 WO1999010320A1 (en) 1997-08-22 1998-08-13 Substituted benzene compounds as antiproliferative and cholesterol lowering agents

Publications (1)

Publication Number Publication Date
ATE280756T1 true ATE280756T1 (de) 2004-11-15

Family

ID=25438246

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98939384T ATE280756T1 (de) 1997-08-22 1998-08-13 Substituierte benzolverbindungen als antiproliferative mittel

Country Status (10)

Country Link
US (2) US6284923B1 (enExample)
EP (1) EP1005453B1 (enExample)
JP (1) JP4309041B2 (enExample)
AT (1) ATE280756T1 (enExample)
AU (1) AU748826B2 (enExample)
CA (1) CA2301842C (enExample)
DE (1) DE69827267T2 (enExample)
ES (1) ES2245803T3 (enExample)
PT (1) PT1005453E (enExample)
WO (1) WO1999010320A1 (enExample)

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US6583157B2 (en) 1998-01-29 2003-06-24 Tularik Inc. Quinolinyl and benzothiazolyl modulators
JP4253126B2 (ja) 1998-01-29 2009-04-08 アムジェン インコーポレイテッド Ｐｐａｒ−ガンマ調節剤
CA2335559A1 (en) * 1998-06-25 1999-12-29 Tularik Inc. Arylsulfonanilide phosphates
KR20010086073A (ko) * 1998-12-02 2001-09-07 데이비드 존 우드 ｐ53계 단백질의 배좌 안정성을 회복하기 위한 방법 및조성물
SG148834A1 (en) * 1999-06-30 2009-01-29 Japan Tobacco Inc Compounds for the modulation of ppary activity
US7041691B1 (en) 1999-06-30 2006-05-09 Amgen Inc. Compounds for the modulation of PPARγ activity
US6306615B1 (en) 1999-08-19 2001-10-23 Tularik Inc. Detection method for monitoring β tubulin isotype specific modification
WO2001082916A2 (en) 2000-05-03 2001-11-08 Tularik Inc. Combination therapeutic compositions and methods of use
US20030171399A1 (en) 2000-06-28 2003-09-11 Tularik Inc. Quinolinyl and benzothiazolyl modulators
US20050250854A1 (en) * 2000-11-03 2005-11-10 Amgen Inc. Combination therapy using pentafluorobenzenesulfonamides and antineoplastic agents
AU2002234165A1 (en) 2000-11-03 2002-05-27 Tularik, Inc. Combination therapy using pentafluorobenzenesulfonamides and antineoplastic agents
WO2003007931A1 (en) * 2001-06-08 2003-01-30 Institute Of Medicinal Molecular Design. Inc. Sulfonamide derivatives
JP2003081937A (ja) * 2001-09-07 2003-03-19 Bayer Ag ベンゼンスルホンアミド誘導体
US7550424B2 (en) * 2002-11-26 2009-06-23 Institute Of Virology Slovak Academy Of Sciences CA IX-specific inhibitors
US7833734B2 (en) * 2002-11-26 2010-11-16 Institute Of Virology Of The Slovak Academy Of Sciences CA IX-specific inhibitors
US7223761B2 (en) 2003-10-03 2007-05-29 Amgen Inc. Salts and polymorphs of a potent antidiabetic compound
FI20055498A0 (fi) * 2005-09-16 2005-09-16 Biotie Therapies Corp Sulfonamidijohdannaisia
GB0526252D0 (en) * 2005-12-22 2006-02-01 Novartis Ag Organic compounds
CA2803118C (en) 2010-07-09 2015-11-03 Pfizer Limited Sulfonamide derivatives as nav 1.7 inhibitors
US8692001B2 (en) 2010-10-27 2014-04-08 Dynamix Pharmaceuticals Ltd. Sulfonamides for the modulation of PKM2
EP2925717A4 (en) * 2012-11-28 2016-08-03 Stichting Dienst Landbouwkundi BENZOLSULFONAMIDE COMPOUNDS FOR PLANTS WITH SOMATIC EMBRYOGENESIS I
CN105452745B (zh) * 2013-08-28 2019-03-19 博格华纳公司 高温阀轴密封
GB201514021D0 (en) 2015-08-07 2015-09-23 Arner Elias Set Jeno Novel Pyridines and their use in the treatment of cancer
EP3580209A1 (en) 2017-02-07 2019-12-18 Oblique Therapeutics AB Heterocyclylsulfonyl-substituted pyridines and their use in the treatment of cancer
KR20190115014A (ko) 2017-02-07 2019-10-10 오블리크 세러퓨틱스 에이비 하이드로카르빌설포닐-치환된 피리딘 및 암의 치료에서 이의 용도
BR112019016223A2 (pt) 2017-02-07 2020-04-07 Oblique Therapeutics Ab piridinas substituídas por heteroarilsulfonila e uso das mesmas no tratamento de câncer
MX2019009356A (es) 2017-02-07 2019-09-19 Oblique Therapeutics Ab Sulfinilpiridinas y su uso en el tratamiento del cancer.
US11555012B2 (en) * 2018-11-09 2023-01-17 Nimbus Artemis, Inc. ACLY inhibitors and uses thereof
US20220281812A1 (en) * 2019-07-17 2022-09-08 2692372 Ontario, Inc. Benzenesulfonamide derivatives and uses thereof
MX2024011428A (es) * 2022-03-21 2024-09-24 Chemocentryx Inc Compuestos de sulfonamida para cxcr6.
WO2024175999A2 (en) * 2023-02-23 2024-08-29 Dunad Therapeutics Ltd. Benzenesulfonamide derivatives and uses thereof

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Also Published As

Publication number Publication date
DE69827267D1 (de) 2004-12-02
DE69827267T2 (de) 2006-02-02
ES2245803T3 (es) 2006-01-16
US6388131B2 (en) 2002-05-14
AU748826B2 (en) 2002-06-13
US6284923B1 (en) 2001-09-04
JP4309041B2 (ja) 2009-08-05
CA2301842C (en) 2010-04-27
AU8782498A (en) 1999-03-16
CA2301842A1 (en) 1999-03-04
EP1005453B1 (en) 2004-10-27
US20020013496A1 (en) 2002-01-31
PT1005453E (pt) 2005-02-28
JP2001514167A (ja) 2001-09-11
WO1999010320A8 (en) 1999-09-23
WO1999010320A1 (en) 1999-03-04
EP1005453A1 (en) 2000-06-07

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