ATE276372T1 - Pichia methanolica glyceraldehyd-3-phosphat- dehydrogenase-1-promoter und -terminator - Google Patents

Pichia methanolica glyceraldehyd-3-phosphat- dehydrogenase-1-promoter und -terminator

Info

Publication number
ATE276372T1
ATE276372T1 AT00944702T AT00944702T ATE276372T1 AT E276372 T1 ATE276372 T1 AT E276372T1 AT 00944702 T AT00944702 T AT 00944702T AT 00944702 T AT00944702 T AT 00944702T AT E276372 T1 ATE276372 T1 AT E276372T1
Authority
AT
Austria
Prior art keywords
terminator
promoter
phosphate dehydrogenase
pichia methanolica
gap1
Prior art date
Application number
AT00944702T
Other languages
English (en)
Inventor
Brady G Miller
James S Sloan
Christopher K Raymond
Erica Vanaja
Original Assignee
Zymogenetics Inc
Brady G Miller
James S Sloan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zymogenetics Inc, Brady G Miller, James S Sloan filed Critical Zymogenetics Inc
Application granted granted Critical
Publication of ATE276372T1 publication Critical patent/ATE276372T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0008Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C12N15/815Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
AT00944702T 1999-06-24 2000-06-16 Pichia methanolica glyceraldehyd-3-phosphat- dehydrogenase-1-promoter und -terminator ATE276372T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14070399P 1999-06-24 1999-06-24
PCT/US2000/016671 WO2000078978A1 (en) 1999-06-24 2000-06-16 Pichia methanolica glyceraldehyde 3-phosphate dehydrogenase 1 promoter and terminator

Publications (1)

Publication Number Publication Date
ATE276372T1 true ATE276372T1 (de) 2004-10-15

Family

ID=22492440

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00944702T ATE276372T1 (de) 1999-06-24 2000-06-16 Pichia methanolica glyceraldehyd-3-phosphat- dehydrogenase-1-promoter und -terminator

Country Status (11)

Country Link
US (1) US6613547B1 (de)
EP (1) EP1192263B1 (de)
JP (1) JP2003503030A (de)
AT (1) ATE276372T1 (de)
AU (1) AU5876300A (de)
CA (1) CA2397494A1 (de)
DE (1) DE60013829T2 (de)
DK (1) DK1192263T3 (de)
ES (1) ES2231217T3 (de)
MX (1) MXPA02000160A (de)
WO (1) WO2000078978A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003091431A1 (fr) * 2002-04-26 2003-11-06 Kirin Beer Kabushiki Kaisha Methylotrophe produisant une chaine de sucre de type mammifere
US7259255B2 (en) * 2003-06-25 2007-08-21 E. I. Du Pont De Nemours And Company Glyceraldehyde-3-phosphate dehydrogenase and phosphoglycerate mutase promoters for gene expression in oleaginous yeast
WO2006065967A2 (en) * 2004-12-15 2006-06-22 General Atomics Allosteric enzyme coupled immunoassay (aecia)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2000101A1 (en) * 1988-12-22 1990-06-22 Mary E. Digan Pichia pastoris glyceraldehyde-3-phosphate dehydrogenase gene
ATE220721T1 (de) * 1990-01-16 2002-08-15 Ct Ingenieria Genetica Biotech Verfahren zur expression heterologischer gene in der hefe pichia pastoris, expressionsvektoren und transformierte mikroorganismen
CA2237039A1 (en) * 1995-11-09 1997-05-15 Zymogenetics, Inc. Production of gad65 in methylotrophic yeast
MX9605082A (es) * 1996-10-24 1998-04-30 Univ Autonoma De Nuevo Leon Levaduras metilotroficas modificadas geneticamente para la produccion y secrecion de hormona de crecimiento humano.
AU9231898A (en) * 1997-09-15 1999-04-05 Zymogenetics Inc. Protease-deficient strains of (pichia methanolica)
US6258559B1 (en) * 1999-03-22 2001-07-10 Zymogenetics, Inc. Method for producing proteins in transformed Pichia

Also Published As

Publication number Publication date
ES2231217T3 (es) 2005-05-16
CA2397494A1 (en) 2000-12-28
EP1192263A1 (de) 2002-04-03
MXPA02000160A (es) 2003-10-14
JP2003503030A (ja) 2003-01-28
WO2000078978A1 (en) 2000-12-28
DE60013829D1 (en) 2004-10-21
DE60013829T2 (de) 2005-09-22
DK1192263T3 (da) 2005-01-31
US6613547B1 (en) 2003-09-02
EP1192263B1 (de) 2004-09-15
AU5876300A (en) 2001-01-09

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