DK1192263T3 - Pichia methanolica glyceraldehyd-3-fosfat dehydrogenase 1 promotor og terminator - Google Patents

Pichia methanolica glyceraldehyd-3-fosfat dehydrogenase 1 promotor og terminator

Info

Publication number
DK1192263T3
DK1192263T3 DK00944702T DK00944702T DK1192263T3 DK 1192263 T3 DK1192263 T3 DK 1192263T3 DK 00944702 T DK00944702 T DK 00944702T DK 00944702 T DK00944702 T DK 00944702T DK 1192263 T3 DK1192263 T3 DK 1192263T3
Authority
DK
Denmark
Prior art keywords
terminator
promoter
phosphate dehydrogenase
pichia methanolica
gap1
Prior art date
Application number
DK00944702T
Other languages
English (en)
Inventor
Brady G Miller
James S Sloan
Christopher K Raymond
Erica Vanaja
Original Assignee
Zymogenetics Inc
Brady G Miller
James S Sloan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zymogenetics Inc, Brady G Miller, James S Sloan filed Critical Zymogenetics Inc
Application granted granted Critical
Publication of DK1192263T3 publication Critical patent/DK1192263T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0008—Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C12N15/815—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
DK00944702T 1999-06-24 2000-06-16 Pichia methanolica glyceraldehyd-3-fosfat dehydrogenase 1 promotor og terminator DK1192263T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US14070399P 1999-06-24 1999-06-24
PCT/US2000/016671 WO2000078978A1 (en) 1999-06-24 2000-06-16 Pichia methanolica glyceraldehyde 3-phosphate dehydrogenase 1 promoter and terminator
EP00944702A EP1192263B1 (en) 1999-06-24 2000-06-16 Pichia methanolica glyceraldehyde-3-phosphate dehydrogenase 1 promoter and terminator

Publications (1)

Publication Number Publication Date
DK1192263T3 true DK1192263T3 (da) 2005-01-31

Family

ID=22492440

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00944702T DK1192263T3 (da) 1999-06-24 2000-06-16 Pichia methanolica glyceraldehyd-3-fosfat dehydrogenase 1 promotor og terminator

Country Status (11)

Country Link
US (1) US6613547B1 (da)
EP (1) EP1192263B1 (da)
JP (1) JP2003503030A (da)
AT (1) ATE276372T1 (da)
AU (1) AU5876300A (da)
CA (1) CA2397494A1 (da)
DE (1) DE60013829T2 (da)
DK (1) DK1192263T3 (da)
ES (1) ES2231217T3 (da)
MX (1) MXPA02000160A (da)
WO (1) WO2000078978A1 (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003091431A1 (fr) * 2002-04-26 2003-11-06 Kirin Beer Kabushiki Kaisha Methylotrophe produisant une chaine de sucre de type mammifere
US7259255B2 (en) * 2003-06-25 2007-08-21 E. I. Du Pont De Nemours And Company Glyceraldehyde-3-phosphate dehydrogenase and phosphoglycerate mutase promoters for gene expression in oleaginous yeast
WO2006065967A2 (en) * 2004-12-15 2006-06-22 General Atomics Allosteric enzyme coupled immunoassay (aecia)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2000101A1 (en) * 1988-12-22 1990-06-22 Mary E. Digan Pichia pastoris glyceraldehyde-3-phosphate dehydrogenase gene
ATE220721T1 (de) * 1990-01-16 2002-08-15 Ct Ingenieria Genetica Biotech Verfahren zur expression heterologischer gene in der hefe pichia pastoris, expressionsvektoren und transformierte mikroorganismen
CA2237039A1 (en) * 1995-11-09 1997-05-15 Zymogenetics, Inc. Production of gad65 in methylotrophic yeast
MX9605082A (es) * 1996-10-24 1998-04-30 Univ Autonoma De Nuevo Leon Levaduras metilotroficas modificadas geneticamente para la produccion y secrecion de hormona de crecimiento humano.
AU9231898A (en) * 1997-09-15 1999-04-05 Zymogenetics Inc. Protease-deficient strains of (pichia methanolica)
US6258559B1 (en) * 1999-03-22 2001-07-10 Zymogenetics, Inc. Method for producing proteins in transformed Pichia

Also Published As

Publication number Publication date
ES2231217T3 (es) 2005-05-16
CA2397494A1 (en) 2000-12-28
EP1192263A1 (en) 2002-04-03
MXPA02000160A (es) 2003-10-14
JP2003503030A (ja) 2003-01-28
WO2000078978A1 (en) 2000-12-28
DE60013829D1 (en) 2004-10-21
DE60013829T2 (de) 2005-09-22
ATE276372T1 (de) 2004-10-15
US6613547B1 (en) 2003-09-02
EP1192263B1 (en) 2004-09-15
AU5876300A (en) 2001-01-09

Similar Documents

Publication Publication Date Title
ATE352626T1 (de) Polypeptide mit galaktoseoxidaseaktivität und dafür kodierende nukleisäuren
EP3704143B1 (en) Chemo-enzymatic synthesis of liraglutide, semaglutide and glp-1
KR880014110A (ko) 인체 프로아포지방단백질 a-i의 발현
ZA967173B (en) Purified coprinus laccases and nucleic acids and encoding same
DE602004028724D1 (de) Verfahren zur herstellung sezernierter polypeptide
NZ335628A (en) Improved expression vectors comprising a nucleic acid construct with tac and gal bacterial promoters
PT917571E (pt) Gene relacionado com agouti
IL155245A (en) Genes for serine protease close to DPPIV
ATE319818T1 (de) Polypeptide mit aminopeptidaseaktivität und für diese kodierende nukleinsäuren
DK0981630T3 (da) Polypeptider med prolyldipeptidylaminopeptidaseaktivitet og nukleinsyrer, der koder for samme
ATE450603T1 (de) Polypeptide mit verzweigungsenzym-aktivität und für diese kodierende nukleinsäuren
DE69535696D1 (de) Tripeptidyl-aminopeptidase
CN102533839B (zh) 融合表达含有二硫键蛋白质的方法
DK0910642T3 (da) Fremgangsmåde til at öge hæmoproteinproduktionen i filamentöse fungi
ATE542913T1 (de) Promotorvarianten zur expression von genen in einer pilzzelle
ATE358725T1 (de) Polypeptide mit aminopeptidaseaktivität und dafür kodierende nukleinsäuren
ES2140398T3 (es) Produccion de factor xiii a por tecnologia genetica.
ATE383420T1 (de) Verwendung des cyp52a2a promotors für die erhöhung der genexpression in hefe
DK1192263T3 (da) Pichia methanolica glyceraldehyd-3-fosfat dehydrogenase 1 promotor og terminator
DK0904356T3 (da) Aspergillus Oryzae 5-aminolevulinsyre-synthaser og nukleinsyrer, der koder disse
HUP0203051A2 (hu) Fehérjék előállítása autoproteolitikus hasítással
HUP0003541A2 (hu) Expressziós vektor polipeptidek javított hatékonyságú előállítására élesztőben
FR2785291B1 (fr) Procede de production in vivo de proteines chimiquement diversifiees par incorporation d'acides amines non conventionnels
DK1032683T3 (da) Polypeptider med 5-aminolevulinsyre-syntase-aktivitet og nukleinsyrer, der koder for disse
Ohnishi et al. Cloning and nucleotide sequences of livB and liv, the structural genes encoding binding proteins of the high-affinity branched-chain amino acid transport in Salmonella typhimurium