AU9231898A - Protease-deficient strains of (pichia methanolica) - Google Patents

Protease-deficient strains of (pichia methanolica)

Info

Publication number
AU9231898A
AU9231898A AU92318/98A AU9231898A AU9231898A AU 9231898 A AU9231898 A AU 9231898A AU 92318/98 A AU92318/98 A AU 92318/98A AU 9231898 A AU9231898 A AU 9231898A AU 9231898 A AU9231898 A AU 9231898A
Authority
AU
Australia
Prior art keywords
protease
pichia methanolica
deficient strains
deficient
strains
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU92318/98A
Inventor
Christopher K. Raymond
Erica Vanaja
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zymogenetics Inc
Original Assignee
Zymogenetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zymogenetics Inc filed Critical Zymogenetics Inc
Publication of AU9231898A publication Critical patent/AU9231898A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/102—Mutagenizing nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C12N15/815—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/58—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi
    • C12N9/60—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi from yeast
AU92318/98A 1997-09-15 1998-09-11 Protease-deficient strains of (pichia methanolica) Abandoned AU9231898A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US92974897A 1997-09-15 1997-09-15
US08929748 1997-09-15
PCT/US1998/019449 WO1999014347A1 (en) 1997-09-15 1998-09-11 PROTEASE-DEFICIENT STRAINS OF $i(PICHIA METHANOLICA)

Publications (1)

Publication Number Publication Date
AU9231898A true AU9231898A (en) 1999-04-05

Family

ID=25458387

Family Applications (1)

Application Number Title Priority Date Filing Date
AU92318/98A Abandoned AU9231898A (en) 1997-09-15 1998-09-11 Protease-deficient strains of (pichia methanolica)

Country Status (2)

Country Link
AU (1) AU9231898A (en)
WO (1) WO1999014347A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000078978A1 (en) * 1999-06-24 2000-12-28 Zymogenetics, Inc. Pichia methanolica glyceraldehyde 3-phosphate dehydrogenase 1 promoter and terminator
US6645739B2 (en) * 2001-07-26 2003-11-11 Phoenix Pharmacologies, Inc. Yeast expression systems, methods of producing polypeptides in yeast, and compositions relating to same
WO2006087366A1 (en) * 2005-02-16 2006-08-24 Cilian Ag Screening method for identifying protease secretion-deficient mutants of microorganisms
EP2401357B1 (en) * 2009-02-26 2015-03-25 GlaxoSmithKline LLC Host cells and methods of use
US8703444B2 (en) 2009-12-14 2014-04-22 Centre Hospitalier Universitaire Vaudois (Chuv) Pichia pastoris deficient in endogenous secreted protease

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE220105T1 (en) * 1991-04-01 2002-07-15 Merck & Co Inc GENES AFFECTING THE PROTEOLYTIC ACTIVITY OF PICHIA AND THEIR USE
EP0862640A2 (en) * 1995-11-09 1998-09-09 ZymoGenetics, Inc. Production of gad65 in methylotrophic yeast

Also Published As

Publication number Publication date
WO1999014347A1 (en) 1999-03-25

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase