ATE273514T1 - Methode zum bestimmen der aktivierung von zytokinrezeptoren mit hilfe eines antikörpers - Google Patents
Methode zum bestimmen der aktivierung von zytokinrezeptoren mit hilfe eines antikörpersInfo
- Publication number
- ATE273514T1 ATE273514T1 AT98911331T AT98911331T ATE273514T1 AT E273514 T1 ATE273514 T1 AT E273514T1 AT 98911331 T AT98911331 T AT 98911331T AT 98911331 T AT98911331 T AT 98911331T AT E273514 T1 ATE273514 T1 AT E273514T1
- Authority
- AT
- Austria
- Prior art keywords
- antibody
- receptor
- conformation
- inactive
- growth hormone
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2869—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against hormone receptors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/575—Hormones
- G01N2333/61—Growth hormones [GH] (Somatotropin)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/715—Assays involving receptors, cell surface antigens or cell surface determinants for cytokines; for lymphokines; for interferons
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9701010A SE9701010D0 (sv) | 1997-03-19 | 1997-03-19 | Antibody |
PCT/SE1998/000496 WO1998041872A1 (en) | 1997-03-19 | 1998-03-19 | Method for determining cytokine receptor activation by the use of an antibody |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE273514T1 true ATE273514T1 (de) | 2004-08-15 |
Family
ID=20406234
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT98911331T ATE273514T1 (de) | 1997-03-19 | 1998-03-19 | Methode zum bestimmen der aktivierung von zytokinrezeptoren mit hilfe eines antikörpers |
Country Status (13)
Country | Link |
---|---|
US (1) | US6645723B2 (de) |
EP (1) | EP0979410B1 (de) |
JP (1) | JP2001524816A (de) |
AT (1) | ATE273514T1 (de) |
AU (1) | AU739758B2 (de) |
CA (1) | CA2285036A1 (de) |
DE (1) | DE69825583T2 (de) |
DK (1) | DK0979410T3 (de) |
ES (1) | ES2224367T3 (de) |
NZ (1) | NZ337636A (de) |
PT (1) | PT979410E (de) |
SE (1) | SE9701010D0 (de) |
WO (1) | WO1998041872A1 (de) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6821738B2 (en) | 1999-01-20 | 2004-11-23 | The Board Of Regents For Oklahoma State University | Broad spectrum bio-detection of nerve agents, organophosphates, and other chemical warfare agents |
GB9904395D0 (en) * | 1999-02-25 | 1999-04-21 | Fluorescience Ltd | Protein assay |
US6972198B2 (en) * | 1999-02-26 | 2005-12-06 | Cyclacel, Ltd. | Methods and compositions using protein binding partners |
DE10306992A1 (de) * | 2003-02-19 | 2005-08-11 | Klinikum der Universität München Großhadern-Innenstadt | Verfahren zur quantitativen Messung von Liganden in der Probe gelöster Bindungsproteine |
SE0301917D0 (sv) | 2003-06-30 | 2003-06-30 | Biovitrum Ab | Methods for identifying active compounds |
JP2005325055A (ja) * | 2004-05-14 | 2005-11-24 | Peptide Door Co Ltd | リガンド結合タンパク質含有複合体及びリガンド結合タンパク質に結合する物質のスクリーニング方法 |
EP3256465B1 (de) * | 2015-02-12 | 2021-04-07 | University of Southern California | Blocker des wachstumshormonrezeptors in der krankheitsvorbeugung und -behandlung |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5593844A (en) * | 1990-11-19 | 1997-01-14 | Genentech, Inc. | Ligand-mediated immunofunctional hormone binding protein assay method |
JP3417558B2 (ja) | 1991-05-10 | 2003-06-16 | ジェネンテク,インコーポレイテッド | 配位子作用薬および拮抗薬の選択 |
WO1993021230A1 (en) * | 1992-04-10 | 1993-10-28 | Dana-Farber Cancer Institute, Inc. | Activation-state-specific phosphoprotein immunodetection |
US5470952A (en) * | 1993-10-20 | 1995-11-28 | Regeneron Pharmaceuticals, Inc. | CNTF and IL-6 antagonists |
-
1997
- 1997-03-19 SE SE9701010A patent/SE9701010D0/xx unknown
-
1998
- 1998-03-19 AU AU65304/98A patent/AU739758B2/en not_active Ceased
- 1998-03-19 JP JP54044798A patent/JP2001524816A/ja not_active Ceased
- 1998-03-19 EP EP98911331A patent/EP0979410B1/de not_active Expired - Lifetime
- 1998-03-19 DE DE69825583T patent/DE69825583T2/de not_active Expired - Fee Related
- 1998-03-19 US US09/044,154 patent/US6645723B2/en not_active Expired - Fee Related
- 1998-03-19 CA CA002285036A patent/CA2285036A1/en not_active Abandoned
- 1998-03-19 WO PCT/SE1998/000496 patent/WO1998041872A1/en active IP Right Grant
- 1998-03-19 NZ NZ337636A patent/NZ337636A/en unknown
- 1998-03-19 DK DK98911331T patent/DK0979410T3/da active
- 1998-03-19 AT AT98911331T patent/ATE273514T1/de not_active IP Right Cessation
- 1998-03-19 PT PT98911331T patent/PT979410E/pt unknown
- 1998-03-19 ES ES98911331T patent/ES2224367T3/es not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
DE69825583T2 (de) | 2005-08-11 |
DE69825583D1 (de) | 2004-09-16 |
EP0979410A1 (de) | 2000-02-16 |
AU6530498A (en) | 1998-10-12 |
ES2224367T3 (es) | 2005-03-01 |
EP0979410B1 (de) | 2004-08-11 |
US6645723B2 (en) | 2003-11-11 |
DK0979410T3 (da) | 2004-11-22 |
AU739758B2 (en) | 2001-10-18 |
WO1998041872A1 (en) | 1998-09-24 |
JP2001524816A (ja) | 2001-12-04 |
PT979410E (pt) | 2004-11-30 |
CA2285036A1 (en) | 1998-09-24 |
US20030077663A1 (en) | 2003-04-24 |
SE9701010D0 (sv) | 1997-03-19 |
NZ337636A (en) | 2001-06-29 |
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Legal Events
Date | Code | Title | Description |
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UEP | Publication of translation of european patent specification |
Ref document number: 0979410 Country of ref document: EP |
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REN | Ceased due to non-payment of the annual fee |