ATE300611T1 - Auf rezeptorgrundlage arbeitende screening- verfahren für protein wechselwirkungen - Google Patents

Auf rezeptorgrundlage arbeitende screening- verfahren für protein wechselwirkungen

Info

Publication number
ATE300611T1
ATE300611T1 AT01960237T AT01960237T ATE300611T1 AT E300611 T1 ATE300611 T1 AT E300611T1 AT 01960237 T AT01960237 T AT 01960237T AT 01960237 T AT01960237 T AT 01960237T AT E300611 T1 ATE300611 T1 AT E300611T1
Authority
AT
Austria
Prior art keywords
receptor
binding
screening methods
protein interactions
based screening
Prior art date
Application number
AT01960237T
Other languages
English (en)
Inventor
Sven Eyckerman
Ostade Xaveer Van
Joel Vandekerckhove
Annick Verhee
Jan Tavernier
Original Assignee
Vlaams Interuniv Inst Biotech
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vlaams Interuniv Inst Biotech filed Critical Vlaams Interuniv Inst Biotech
Application granted granted Critical
Publication of ATE300611T1 publication Critical patent/ATE300611T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1055—Protein x Protein interaction, e.g. two hybrid selection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/90—Fusion polypeptide containing a motif for post-translational modification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/027—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a retrovirus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/06—Uses of viruses as vector in vitro
AT01960237T 2000-05-22 2001-05-22 Auf rezeptorgrundlage arbeitende screening- verfahren für protein wechselwirkungen ATE300611T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP00201771 2000-05-22
PCT/EP2001/005916 WO2001090188A2 (en) 2000-05-22 2001-05-22 Receptor-based interaction trap

Publications (1)

Publication Number Publication Date
ATE300611T1 true ATE300611T1 (de) 2005-08-15

Family

ID=8171515

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01960237T ATE300611T1 (de) 2000-05-22 2001-05-22 Auf rezeptorgrundlage arbeitende screening- verfahren für protein wechselwirkungen

Country Status (8)

Country Link
US (2) US7855270B2 (de)
EP (2) EP1283878B1 (de)
JP (1) JP4756813B2 (de)
AT (1) ATE300611T1 (de)
AU (2) AU8178401A (de)
CA (1) CA2407872C (de)
DE (1) DE60112282T2 (de)
WO (1) WO2001090188A2 (de)

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GB201103453D0 (en) 2011-03-01 2011-04-13 Vib Vzw Kinase substrate sensor
US9746470B2 (en) * 2011-05-09 2017-08-29 Whitehead Institute For Biomedical Research Chaperone interaction assays and uses thereof
US10336811B2 (en) 2012-03-06 2019-07-02 Vib Vzw Membrane span-kinase fusion protein and the uses thereof
CA2874268C (en) 2012-05-24 2022-06-07 Universiteit Gent Virus-like particle based protein-protein interaction
GB201504859D0 (en) 2015-03-23 2015-05-06 Vib Vzw Viral particle based small molecule-protein interaction trap
GB201909491D0 (en) * 2019-07-01 2019-08-14 Governing Council Of The Univ Of Toronto Detection of protein to protein interactions
CN115210381A (zh) * 2019-12-17 2022-10-18 奥里尼斯生物科学股份有限公司 新型降解相关相互作用的检测
US20230026360A1 (en) * 2019-12-17 2023-01-26 Orionis Biosciences, Inc. Detection of molecular interactions
CA3232203A1 (en) * 2021-09-22 2023-03-30 James MATTHAEI Il5ra cell surface markers

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Also Published As

Publication number Publication date
JP4756813B2 (ja) 2011-08-24
EP1612221A2 (de) 2006-01-04
CA2407872A1 (en) 2001-11-29
DE60112282D1 (de) 2005-09-01
EP1283878B1 (de) 2005-07-27
WO2001090188A9 (en) 2002-09-19
AU2001281784B2 (en) 2005-09-15
CA2407872C (en) 2013-11-12
EP1283878A2 (de) 2003-02-19
WO2001090188A3 (en) 2002-06-13
US20030100021A1 (en) 2003-05-29
JP2003533998A (ja) 2003-11-18
AU8178401A (en) 2001-12-03
US7855270B2 (en) 2010-12-21
US20100173408A1 (en) 2010-07-08
WO2001090188A2 (en) 2001-11-29
EP1612221A3 (de) 2008-07-23
DE60112282T2 (de) 2006-04-20
US8003757B2 (en) 2011-08-23

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