DE69926624D1 - Verfahren zum screenen einer die oligomerisierung von rezeptorproteinmolekülen fördernden substanz - Google Patents

Verfahren zum screenen einer die oligomerisierung von rezeptorproteinmolekülen fördernden substanz

Info

Publication number
DE69926624D1
DE69926624D1 DE69926624T DE69926624T DE69926624D1 DE 69926624 D1 DE69926624 D1 DE 69926624D1 DE 69926624 T DE69926624 T DE 69926624T DE 69926624 T DE69926624 T DE 69926624T DE 69926624 D1 DE69926624 D1 DE 69926624D1
Authority
DE
Germany
Prior art keywords
receptor protein
protein molecules
oligomerization
screening
peptide fragments
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69926624T
Other languages
English (en)
Other versions
DE69926624T2 (de
Inventor
M Higuchi
Y Shimonaka
Keiko Esaki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chugai Pharmaceutical Co Ltd
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Publication of DE69926624D1 publication Critical patent/DE69926624D1/de
Application granted granted Critical
Publication of DE69926624T2 publication Critical patent/DE69926624T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G01N33/746—Erythropoetin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/475—Assays involving growth factors
    • G01N2333/505—Erythropoietin [EPO]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/71—Assays involving receptors, cell surface antigens or cell surface determinants for growth factors; for growth regulators
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/20—Screening for compounds of potential therapeutic value cell-free systems

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DE69926624T 1998-04-14 1999-04-13 Verfahren zum screenen einer die oligomerisierung von rezeptorproteinmolekülen fördernden substanz Expired - Lifetime DE69926624T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP10232598 1998-04-14
JP10232598 1998-04-14
PCT/JP1999/001965 WO1999053313A1 (fr) 1998-04-14 1999-04-13 Procede de recherche d'une substance favorisant l'oligomerisation de molecules de proteines receptrices

Publications (2)

Publication Number Publication Date
DE69926624D1 true DE69926624D1 (de) 2005-09-15
DE69926624T2 DE69926624T2 (de) 2006-05-18

Family

ID=14324407

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69926624T Expired - Lifetime DE69926624T2 (de) 1998-04-14 1999-04-13 Verfahren zum screenen einer die oligomerisierung von rezeptorproteinmolekülen fördernden substanz

Country Status (8)

Country Link
US (1) US20070238128A9 (de)
EP (1) EP1079230B1 (de)
JP (1) JP4397122B2 (de)
AT (1) ATE301833T1 (de)
AU (1) AU3169599A (de)
DE (1) DE69926624T2 (de)
ES (1) ES2247790T3 (de)
WO (1) WO1999053313A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0007217D0 (en) * 2000-03-24 2000-05-17 Europ I Of Oncology Materials and methods relating to the treatment of leukaemias
EP1469309A4 (de) * 2001-12-27 2007-11-21 Japan Science & Tech Agency Verfahren zur beurteilung der zellaktivität

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6247555A (ja) * 1985-08-23 1987-03-02 エフ．ホフマン　―　ラ　ロシュ　アーゲー シンチレ−シヨン近接定量法
DE69231467T2 (de) * 1991-05-10 2001-01-25 Genentech, Inc. Auswählen von agonisten und antagonisten von liganden
DE4228839A1 (de) * 1992-08-29 1994-03-03 Behringwerke Ag Verfahren zum Nachweis und zur Bestimmung von Mediatoren

Also Published As

Publication number Publication date
JP4397122B2 (ja) 2010-01-13
EP1079230A4 (de) 2001-12-12
EP1079230B1 (de) 2005-08-10
AU3169599A (en) 1999-11-01
ATE301833T1 (de) 2005-08-15
DE69926624T2 (de) 2006-05-18
WO1999053313A1 (fr) 1999-10-21
ES2247790T3 (es) 2006-03-01
EP1079230A1 (de) 2001-02-28
US20070238128A9 (en) 2007-10-11
US20060183153A1 (en) 2006-08-17

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition