ATE368750T1 - Screening-verfahren zum identifizieren von g- proteinen und anderen verbindungen,die die phosphodiesterase (pde)-aktivität beeinflussen - Google Patents
Screening-verfahren zum identifizieren von g- proteinen und anderen verbindungen,die die phosphodiesterase (pde)-aktivität beeinflussenInfo
- Publication number
- ATE368750T1 ATE368750T1 AT01979243T AT01979243T ATE368750T1 AT E368750 T1 ATE368750 T1 AT E368750T1 AT 01979243 T AT01979243 T AT 01979243T AT 01979243 T AT01979243 T AT 01979243T AT E368750 T1 ATE368750 T1 AT E368750T1
- Authority
- AT
- Austria
- Prior art keywords
- proteins
- compounds
- relates
- pde
- identifying
- Prior art date
Links
- 102000004861 Phosphoric Diester Hydrolases Human genes 0.000 title abstract 3
- 108090001050 Phosphoric Diester Hydrolases Proteins 0.000 title abstract 3
- 150000001875 compounds Chemical class 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 3
- 238000012216 screening Methods 0.000 title 1
- 108091006027 G proteins Proteins 0.000 abstract 3
- 102000030782 GTP binding Human genes 0.000 abstract 3
- 108091000058 GTP-Binding Proteins 0.000 abstract 3
- 230000019491 signal transduction Effects 0.000 abstract 2
- 230000011664 signaling Effects 0.000 abstract 2
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 230000004913 activation Effects 0.000 abstract 1
- 238000003556 assay Methods 0.000 abstract 1
- 239000012636 effector Substances 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/44—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving esterase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/72—Assays involving receptors, cell surface antigens or cell surface determinants for hormones
- G01N2333/726—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/02—Screening involving studying the effect of compounds C on the interaction between interacting molecules A and B (e.g. A = enzyme and B = substrate for A, or A = receptor and B = ligand for the receptor)
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- General Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pathology (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Peptides Or Proteins (AREA)
- Enzymes And Modification Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23255200P | 2000-09-14 | 2000-09-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE368750T1 true ATE368750T1 (de) | 2007-08-15 |
Family
ID=22873601
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01979243T ATE368750T1 (de) | 2000-09-14 | 2001-09-14 | Screening-verfahren zum identifizieren von g- proteinen und anderen verbindungen,die die phosphodiesterase (pde)-aktivität beeinflussen |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7179614B2 (de) |
| EP (1) | EP1317564B1 (de) |
| AT (1) | ATE368750T1 (de) |
| AU (1) | AU2002211228A1 (de) |
| CA (1) | CA2421938A1 (de) |
| DE (1) | DE60129719T2 (de) |
| DK (1) | DK1317564T3 (de) |
| ES (1) | ES2291362T3 (de) |
| WO (1) | WO2002022649A2 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7803982B2 (en) | 2001-04-20 | 2010-09-28 | The Mount Sinai School Of Medicine Of New York University | T1R3 transgenic animals, cells and related methods |
| EP1572871A4 (de) * | 2001-04-20 | 2007-11-14 | Sinai School Medicine | T1r3, ein neuer geschmacksrezeptor |
| US20050260258A1 (en) | 2003-12-18 | 2005-11-24 | The Texas A&M University System | Use of vitelline protein B as a microencapsulating additive |
| US9128079B2 (en) | 2011-08-08 | 2015-09-08 | The Coca-Cola Company | Methods of using lung or bronchial epithelial cells to identify bitter taste modulators |
| WO2014169087A2 (en) * | 2013-04-10 | 2014-10-16 | The Trustees Of Columbia University In The City Of New York | Treatment of proximal spinal muscular atrophy |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5168062A (en) * | 1985-01-30 | 1992-12-01 | University Of Iowa Research Foundation | Transfer vectors and microorganisms containing human cytomegalovirus immediate-early promoter-regulatory DNA sequence |
| US5034506A (en) * | 1985-03-15 | 1991-07-23 | Anti-Gene Development Group | Uncharged morpholino-based polymers having achiral intersubunit linkages |
| IL92124A (en) | 1988-10-28 | 1996-10-31 | Sidney Pestka | Recombinant proteins modified to contain post-phosphorylation that do not occur in nature |
| DE69002618T2 (de) * | 1990-06-06 | 1994-03-10 | Propper Mfg Co Inc | Biologische Sterilisationstestpackung. |
| US5792844A (en) * | 1990-07-27 | 1998-08-11 | Isis Pharmaceuticals, Inc. | Oligonucleoside linkages containing adjacent nitrogen atoms |
| US5677437A (en) * | 1990-07-27 | 1997-10-14 | Isis Pharmaceuticals, Inc. | Heteroatomic oligonucleoside linkages |
| US5783682A (en) * | 1990-07-27 | 1998-07-21 | Isis Pharmaceuticals, Inc. | Oligonucleotide mimics having nitrogen-containing linkages |
| JP3895366B2 (ja) | 1990-09-25 | 2007-03-22 | キャンタブ ファーマシューティカルズ リサーチ リミティド | ウィルス ワクチン |
| US5217889A (en) * | 1990-10-19 | 1993-06-08 | Roninson Igor B | Methods and applications for efficient genetic suppressor elements |
| WO1992018541A1 (en) * | 1991-04-19 | 1992-10-29 | The Board Of Regents Of The University Of Washington | Dna encoding mammalian phosphodiesterases |
| US6008000A (en) * | 1992-04-09 | 1999-12-28 | Linguagen Corporation | Gustducin materials and methods |
| US5817759A (en) * | 1992-04-09 | 1998-10-06 | Linguagen Corporation | Gustducin polypeptides and fragments |
| US5281400A (en) * | 1992-09-30 | 1994-01-25 | Carr Metal Products | Plastic autoclave tray and lid combination |
| CA2158148A1 (en) | 1993-03-19 | 1994-09-29 | Stephen Charles Inglis | Defective mutant non-retroviral virus (e.g. hsv) as vaccine |
| ES2333691T3 (es) * | 1993-05-27 | 2010-02-26 | Board Of Regents Of The University Of Washington | Union a gmp ciclica, materiales de fosfodiesterasa especificos a gmp ciclicos y metodos. |
| US5637684A (en) * | 1994-02-23 | 1997-06-10 | Isis Pharmaceuticals, Inc. | Phosphoramidate and phosphorothioamidate oligomeric compounds |
| CA2187818A1 (en) | 1994-04-15 | 1995-10-26 | Robert W. Overell | Gene delivery fusion proteins |
| AU702075B2 (en) * | 1994-04-26 | 1999-02-11 | Cadus Pharmaceutical Corporation | Functional expression of mammalian adenylyl cyclase in yeast |
| CA2135253A1 (en) * | 1994-11-07 | 1996-05-08 | Michael Dennis | Compound screening based on a window of chemical-messenger-independent activity |
| WO1997014709A1 (en) * | 1995-10-13 | 1997-04-24 | F. Hoffmann-La Roche Ag | Antisense oligomers |
| US5814500A (en) * | 1996-10-31 | 1998-09-29 | The Johns Hopkins University School Of Medicine | Delivery construct for antisense nucleic acids and methods of use |
| US6096272A (en) * | 1997-05-23 | 2000-08-01 | Becton Dickinson & Company | Automated microbiological testing apparatus and methods therefor |
| US5834313A (en) * | 1997-09-19 | 1998-11-10 | Johnson & Johnson Medical, Inc. | Container monitoring system |
| US6815206B2 (en) * | 1997-09-19 | 2004-11-09 | Ethicon, Inc. | Container monitoring system |
| US6355448B1 (en) * | 1998-06-02 | 2002-03-12 | 3M Innovative Properties Company | Sterilization indicator with chemically stabilized enzyme |
| WO2000027861A1 (en) | 1998-11-12 | 2000-05-18 | The Board Of Trustees Of The Leland Stanford Junior University | Novel phosphodiesterase interacting proteins |
| GB9927331D0 (en) * | 1999-11-18 | 2000-01-12 | Fluorescience Ltd | Assay for measuring enzyme activity in vivo |
| AU2001270129A1 (en) * | 2000-06-22 | 2002-01-02 | Incyte Genomics, Inc. | Human phosphodiesterases |
| US20030108643A1 (en) * | 2001-10-24 | 2003-06-12 | Walter Hornsby | System and method for packaging meat products in low oxygen environment |
-
2001
- 2001-09-14 ES ES01979243T patent/ES2291362T3/es not_active Expired - Lifetime
- 2001-09-14 EP EP01979243A patent/EP1317564B1/de not_active Expired - Lifetime
- 2001-09-14 US US10/380,393 patent/US7179614B2/en not_active Expired - Fee Related
- 2001-09-14 AT AT01979243T patent/ATE368750T1/de not_active IP Right Cessation
- 2001-09-14 AU AU2002211228A patent/AU2002211228A1/en not_active Abandoned
- 2001-09-14 DE DE60129719T patent/DE60129719T2/de not_active Expired - Fee Related
- 2001-09-14 WO PCT/US2001/028663 patent/WO2002022649A2/en not_active Ceased
- 2001-09-14 DK DK01979243T patent/DK1317564T3/da active
- 2001-09-14 CA CA002421938A patent/CA2421938A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2002022649A3 (en) | 2002-05-30 |
| DE60129719T2 (de) | 2008-06-05 |
| DE60129719D1 (de) | 2007-09-13 |
| WO2002022649A2 (en) | 2002-03-21 |
| EP1317564B1 (de) | 2007-08-01 |
| AU2002211228A1 (en) | 2002-03-26 |
| US7179614B2 (en) | 2007-02-20 |
| DK1317564T3 (da) | 2007-12-03 |
| EP1317564A4 (de) | 2005-01-19 |
| US20040063148A1 (en) | 2004-04-01 |
| EP1317564A2 (de) | 2003-06-11 |
| CA2421938A1 (en) | 2002-03-21 |
| ES2291362T3 (es) | 2008-03-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1317564 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |