ATE269089T1 - Verwendung von vitamin d derivaten zur verstärkung der wirkung von zytotoxischen stoffen - Google Patents

Verwendung von vitamin d derivaten zur verstärkung der wirkung von zytotoxischen stoffen

Info

Publication number
ATE269089T1
ATE269089T1 AT98957308T AT98957308T ATE269089T1 AT E269089 T1 ATE269089 T1 AT E269089T1 AT 98957308 T AT98957308 T AT 98957308T AT 98957308 T AT98957308 T AT 98957308T AT E269089 T1 ATE269089 T1 AT E269089T1
Authority
AT
Austria
Prior art keywords
vitamin
derivatives
increase
effect
cytotoxic
Prior art date
Application number
AT98957308T
Other languages
English (en)
Inventor
Candace Johnson
Donald Trump
Original Assignee
Univ Pittsburgh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Pittsburgh filed Critical Univ Pittsburgh
Application granted granted Critical
Publication of ATE269089T1 publication Critical patent/ATE269089T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/59Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/675Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/243Platinum; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT98957308T 1997-08-29 1998-08-27 Verwendung von vitamin d derivaten zur verstärkung der wirkung von zytotoxischen stoffen ATE269089T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/921,170 US6087350A (en) 1997-08-29 1997-08-29 Use of pretreatment chemicals to enhance efficacy of cytotoxic agents
PCT/US1998/017732 WO1999016451A1 (en) 1997-08-29 1998-08-27 Use of vitamin d derivatives to enhance efficacy of cytotoxic agents

Publications (1)

Publication Number Publication Date
ATE269089T1 true ATE269089T1 (de) 2004-07-15

Family

ID=25445023

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98957308T ATE269089T1 (de) 1997-08-29 1998-08-27 Verwendung von vitamin d derivaten zur verstärkung der wirkung von zytotoxischen stoffen

Country Status (10)

Country Link
US (5) US6087350A (de)
EP (2) EP1491198A1 (de)
JP (1) JP2001517705A (de)
AT (1) ATE269089T1 (de)
AU (1) AU1359499A (de)
DE (1) DE69824622T2 (de)
DK (1) DK1030670T3 (de)
ES (1) ES2222615T3 (de)
PT (1) PT1030670E (de)
WO (1) WO1999016451A1 (de)

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AU1359499A (en) 1999-04-23
US20030176403A1 (en) 2003-09-18
PT1030670E (pt) 2004-09-30
EP1491198A1 (de) 2004-12-29
WO1999016451A1 (en) 1999-04-08
DE69824622T2 (de) 2009-09-24
JP2001517705A (ja) 2001-10-09
US20030216359A1 (en) 2003-11-20
EP1030670B1 (de) 2004-06-16
US20080003304A1 (en) 2008-01-03
US6087350A (en) 2000-07-11
DK1030670T3 (da) 2004-10-04
EP1030670A1 (de) 2000-08-30
US6559139B1 (en) 2003-05-06
ES2222615T3 (es) 2005-02-01
DE69824622D1 (de) 2004-07-22

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