ATE269089T1 - Verwendung von vitamin d derivaten zur verstärkung der wirkung von zytotoxischen stoffen - Google Patents
Verwendung von vitamin d derivaten zur verstärkung der wirkung von zytotoxischen stoffenInfo
- Publication number
- ATE269089T1 ATE269089T1 AT98957308T AT98957308T ATE269089T1 AT E269089 T1 ATE269089 T1 AT E269089T1 AT 98957308 T AT98957308 T AT 98957308T AT 98957308 T AT98957308 T AT 98957308T AT E269089 T1 ATE269089 T1 AT E269089T1
- Authority
- AT
- Austria
- Prior art keywords
- vitamin
- derivatives
- increase
- effect
- cytotoxic
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/243—Platinum; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Inorganic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/921,170 US6087350A (en) | 1997-08-29 | 1997-08-29 | Use of pretreatment chemicals to enhance efficacy of cytotoxic agents |
PCT/US1998/017732 WO1999016451A1 (en) | 1997-08-29 | 1998-08-27 | Use of vitamin d derivatives to enhance efficacy of cytotoxic agents |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE269089T1 true ATE269089T1 (de) | 2004-07-15 |
Family
ID=25445023
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT98957308T ATE269089T1 (de) | 1997-08-29 | 1998-08-27 | Verwendung von vitamin d derivaten zur verstärkung der wirkung von zytotoxischen stoffen |
Country Status (10)
Country | Link |
---|---|
US (5) | US6087350A (de) |
EP (2) | EP1491198A1 (de) |
JP (1) | JP2001517705A (de) |
AT (1) | ATE269089T1 (de) |
AU (1) | AU1359499A (de) |
DE (1) | DE69824622T2 (de) |
DK (1) | DK1030670T3 (de) |
ES (1) | ES2222615T3 (de) |
PT (1) | PT1030670E (de) |
WO (1) | WO1999016451A1 (de) |
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US6573256B2 (en) | 1996-12-30 | 2003-06-03 | Bone Care International, Inc. | Method of inhibiting angiogenesis using active vitamin D analogues |
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US6087350A (en) * | 1997-08-29 | 2000-07-11 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Use of pretreatment chemicals to enhance efficacy of cytotoxic agents |
US6521608B1 (en) | 1998-03-27 | 2003-02-18 | Oregon Health & Science University | Vitamin D and its analogs in the treatment of tumors and other hyperproliferative disorders |
CA2370003C (en) | 1999-01-13 | 2008-08-19 | Tracey Brown | A composition and method for the enhancement of the efficacy of drugs |
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US20060189586A1 (en) * | 2003-06-11 | 2006-08-24 | Cleland Jeffrey L | Pharmaceutical compositions comprising active vitamin D compounds |
JP2007501865A (ja) * | 2003-06-11 | 2007-02-01 | ノバセア インコーポレイティッド | 放射線治療薬および放射線治療と併用した、活性ビタミンd化合物による癌の治療法 |
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US20190038641A1 (en) * | 2016-02-04 | 2019-02-07 | The Board Of Regents Of The University Of Texas System | Combination therapy for castration-resistant prostrate cancer |
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US6359152B2 (en) * | 1997-07-21 | 2002-03-19 | Wisconsin Alumni Research Foundation | 18-substituted-19-nor-vitamin D compounds |
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US6087350A (en) | 1997-08-29 | 2000-07-11 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Use of pretreatment chemicals to enhance efficacy of cytotoxic agents |
US6521608B1 (en) * | 1998-03-27 | 2003-02-18 | Oregon Health & Science University | Vitamin D and its analogs in the treatment of tumors and other hyperproliferative disorders |
AUPP332898A0 (en) | 1998-05-04 | 1998-05-28 | Unisearch Limited | Pharmaceutical composition |
US6114317A (en) * | 1998-05-21 | 2000-09-05 | Wisconsin Alumni Research Foundation | Method of locking 1α-OH of vitamin D compounds in axial orientation |
US5972917A (en) | 1998-05-29 | 1999-10-26 | Bone Care Int Inc | 1 α-hydroxy-25-ene-vitamin D, analogs and uses thereof |
US6552009B2 (en) * | 1998-07-16 | 2003-04-22 | Gentrix Llc | Compositions and methods of treating abnormal cell proliferation |
US20010002396A1 (en) * | 1998-07-16 | 2001-05-31 | Charles Achkar | Compositions and methods of treating skin conditions |
US6218430B1 (en) * | 1998-08-24 | 2001-04-17 | Ligand Pharmaceuticals Incorporated | Vitamin D3 mimics |
CA2348235A1 (en) * | 1998-10-23 | 2000-05-04 | Teijin Limited | Vitamin d3 derivatives and treating agent for inflammatory respiratory disease using same |
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US6267985B1 (en) | 1999-06-30 | 2001-07-31 | Lipocine Inc. | Clear oil-containing pharmaceutical compositions |
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PL353639A1 (en) * | 1999-07-16 | 2003-12-01 | Leo Pharma A/Sleo Pharma A/S | Aminobenzophenones as inhibitors of il-1beta and tnf-alpha |
US6051567A (en) * | 1999-08-02 | 2000-04-18 | Abbott Laboratories | Low oxygen content compositions of 1α, 25-dihydroxycholecalciferol |
FR2798855B1 (fr) * | 1999-09-28 | 2003-04-25 | Oreal | Utilisation de complexes inorganiques-organiques dans une composition a usage topique |
US6703380B2 (en) * | 1999-09-29 | 2004-03-09 | Colotech A/S | Prevention of cancer |
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CN1193003C (zh) * | 1999-12-06 | 2005-03-16 | 里奥制药有限公司 | 作为IL-1β与TNF-α抑制剂的氨基二苯酮 |
US6989377B2 (en) * | 1999-12-21 | 2006-01-24 | Wisconsin Alumni Research Foundation | Treating vitamin D responsive diseases |
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-
1997
- 1997-08-29 US US08/921,170 patent/US6087350A/en not_active Expired - Fee Related
-
1998
- 1998-08-27 AT AT98957308T patent/ATE269089T1/de active
- 1998-08-27 WO PCT/US1998/017732 patent/WO1999016451A1/en active IP Right Grant
- 1998-08-27 JP JP2000513585A patent/JP2001517705A/ja active Pending
- 1998-08-27 EP EP20040014012 patent/EP1491198A1/de not_active Withdrawn
- 1998-08-27 DK DK98957308T patent/DK1030670T3/da active
- 1998-08-27 DE DE69824622T patent/DE69824622T2/de not_active Expired - Lifetime
- 1998-08-27 EP EP98957308A patent/EP1030670B1/de not_active Expired - Lifetime
- 1998-08-27 ES ES98957308T patent/ES2222615T3/es not_active Expired - Lifetime
- 1998-08-27 PT PT98957308T patent/PT1030670E/pt unknown
- 1998-10-06 AU AU13594/99A patent/AU1359499A/en not_active Abandoned
-
2000
- 2000-04-06 US US09/544,724 patent/US6559139B1/en not_active Expired - Fee Related
-
2003
- 2003-03-17 US US10/390,234 patent/US20030176403A1/en not_active Abandoned
- 2003-05-05 US US10/429,840 patent/US20030216359A1/en not_active Abandoned
-
2007
- 2007-01-29 US US11/668,330 patent/US20080003304A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
AU1359499A (en) | 1999-04-23 |
US20030176403A1 (en) | 2003-09-18 |
PT1030670E (pt) | 2004-09-30 |
EP1491198A1 (de) | 2004-12-29 |
WO1999016451A1 (en) | 1999-04-08 |
DE69824622T2 (de) | 2009-09-24 |
JP2001517705A (ja) | 2001-10-09 |
US20030216359A1 (en) | 2003-11-20 |
EP1030670B1 (de) | 2004-06-16 |
US20080003304A1 (en) | 2008-01-03 |
US6087350A (en) | 2000-07-11 |
DK1030670T3 (da) | 2004-10-04 |
EP1030670A1 (de) | 2000-08-30 |
US6559139B1 (en) | 2003-05-06 |
ES2222615T3 (es) | 2005-02-01 |
DE69824622D1 (de) | 2004-07-22 |
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