ATE269070T1 - Verwendung von histondecarboxylase-hemmern zur behandlung der fibrose - Google Patents

Verwendung von histondecarboxylase-hemmern zur behandlung der fibrose

Info

Publication number
ATE269070T1
ATE269070T1 AT97202644T AT97202644T ATE269070T1 AT E269070 T1 ATE269070 T1 AT E269070T1 AT 97202644 T AT97202644 T AT 97202644T AT 97202644 T AT97202644 T AT 97202644T AT E269070 T1 ATE269070 T1 AT E269070T1
Authority
AT
Austria
Prior art keywords
fibrosis
trichostatin
histone
collagens
decarboxylase inhibitors
Prior art date
Application number
AT97202644T
Other languages
English (en)
Inventor
Albert Emmanuel Corneil Geerts
Toshiro Niki
Original Assignee
Univ Bruxelles
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Bruxelles filed Critical Univ Bruxelles
Application granted granted Critical
Publication of ATE269070T1 publication Critical patent/ATE269070T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT97202644T 1996-09-04 1997-08-29 Verwendung von histondecarboxylase-hemmern zur behandlung der fibrose ATE269070T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP96202460A EP0827742A1 (de) 1996-09-04 1996-09-04 Verwendung von Histondeacetylasehemmern zur Behandlung von Fibrose oder Zirrhose

Publications (1)

Publication Number Publication Date
ATE269070T1 true ATE269070T1 (de) 2004-07-15

Family

ID=8224350

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97202644T ATE269070T1 (de) 1996-09-04 1997-08-29 Verwendung von histondecarboxylase-hemmern zur behandlung der fibrose

Country Status (8)

Country Link
US (1) US5993845A (de)
EP (2) EP0827742A1 (de)
JP (1) JPH10114681A (de)
AT (1) ATE269070T1 (de)
DE (1) DE69729517D1 (de)
DK (1) DK0827743T3 (de)
ES (1) ES2218638T3 (de)
PT (1) PT827743E (de)

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Also Published As

Publication number Publication date
DK0827743T3 (da) 2004-10-11
EP0827743A1 (de) 1998-03-11
PT827743E (pt) 2004-08-31
JPH10114681A (ja) 1998-05-06
EP0827743B1 (de) 2004-06-16
EP0827742A1 (de) 1998-03-11
DE69729517D1 (de) 2004-07-22
ES2218638T3 (es) 2004-11-16
US5993845A (en) 1999-11-30

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