ATE261308T1 - Dextran formulierungen zur behandlung entzündlicher gelenkerkrankungen - Google Patents

Dextran formulierungen zur behandlung entzündlicher gelenkerkrankungen

Info

Publication number
ATE261308T1
ATE261308T1 AT99909118T AT99909118T ATE261308T1 AT E261308 T1 ATE261308 T1 AT E261308T1 AT 99909118 T AT99909118 T AT 99909118T AT 99909118 T AT99909118 T AT 99909118T AT E261308 T1 ATE261308 T1 AT E261308T1
Authority
AT
Austria
Prior art keywords
dextran
treatment
molecular weight
joint diseases
inflammatory joint
Prior art date
Application number
AT99909118T
Other languages
English (en)
Inventor
June Ha Green
Peter B Buckley
Original Assignee
Glenpharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glenpharma filed Critical Glenpharma
Application granted granted Critical
Publication of ATE261308T1 publication Critical patent/ATE261308T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
    • C08B37/0021—Dextran, i.e. (alpha-1,4)-D-glucan; Derivatives thereof, e.g. Sephadex, i.e. crosslinked dextran
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Rheumatology (AREA)
  • Polymers & Plastics (AREA)
  • Materials Engineering (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
AT99909118T 1998-03-27 1999-03-25 Dextran formulierungen zur behandlung entzündlicher gelenkerkrankungen ATE261308T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/049,055 US5902800A (en) 1998-03-27 1998-03-27 Dextran formulations and method for treatment of inflammatory joint disorders
PCT/IB1999/000525 WO1999049874A1 (en) 1998-03-27 1999-03-25 Dextran formulations and method for treatment of inflammatory joint disorders

Publications (1)

Publication Number Publication Date
ATE261308T1 true ATE261308T1 (de) 2004-03-15

Family

ID=21957832

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99909118T ATE261308T1 (de) 1998-03-27 1999-03-25 Dextran formulierungen zur behandlung entzündlicher gelenkerkrankungen

Country Status (12)

Country Link
US (1) US5902800A (de)
EP (1) EP1066044B1 (de)
JP (1) JP4511031B2 (de)
AT (1) ATE261308T1 (de)
AU (1) AU753124B2 (de)
BR (1) BR9909199A (de)
CA (1) CA2326510C (de)
DE (1) DE69915458T2 (de)
DK (1) DK1066044T3 (de)
ES (1) ES2217741T3 (de)
MX (1) MXPA00009159A (de)
WO (1) WO1999049874A1 (de)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19908441C1 (de) * 1999-02-26 2000-08-31 Chakravarty Adusumalli Injektionslösung zur Behandlung von Arthrosen
US6800298B1 (en) * 2000-05-11 2004-10-05 Clemson University Biological lubricant composition and method of applying lubricant composition
US7387796B2 (en) * 2002-01-30 2008-06-17 Hebert Rolland F Stable compositions of S-adenosyl-l-methionine with dextran
WO2004000915A2 (en) 2002-06-24 2003-12-31 Tufts University Silk biomaterials and methods of use thereof
JP4698596B2 (ja) 2003-04-10 2011-06-08 タフツ ユニバーシティー 濃縮された水性シルクフィブロイン溶液およびそれらの使用
CA2608862C (en) 2004-06-11 2020-05-05 Trustees Of Tufts College Silk-based drug delivery system
WO2008118133A2 (en) 2006-09-26 2008-10-02 Trustees Of Tufts College Silk microspheres for encapsulation and controlled release
JP2010522583A (ja) 2007-02-27 2010-07-08 トラスティーズ オブ タフツ カレッジ 組織工学的に作製された絹製臓器
WO2008130587A2 (en) 2007-04-16 2008-10-30 Corium International, Inc. Solvent-cast microneedle arrays containing active
US9808557B2 (en) 2007-08-10 2017-11-07 Trustees Of Tufts College Tubular silk compositions and methods of use thereof
WO2011037912A1 (en) * 2009-09-23 2011-03-31 Glenpharma Ab Compositions and methods for inducing or enhancing connective tissue repair
EP2566501B1 (de) 2010-05-04 2019-03-13 Corium International, Inc. Verfahren und vorrichtung zur transdermalen verabreichung von parathormon mithilfe eines mikroprojektions-arrays
WO2011160146A1 (en) 2010-06-23 2011-12-29 Croma-Pharma Gesellschaft M.B.H. Pharmaceutical preparation containing dextran and sodium hyaluronate for the treatment of joint disorders
GB201020300D0 (en) * 2010-11-30 2011-01-12 Vitrolife Sweden Ab Product
WO2012145652A1 (en) 2011-04-20 2012-10-26 Trustees Of Tufts College Dynamic silk coatings for implantable devices
US9554989B2 (en) 2012-03-20 2017-01-31 Trustees Of Tufts College Silk reservoirs for drug delivery
CN104602713A (zh) 2012-04-13 2015-05-06 塔夫茨大学信托人 用于制备丝微球的方法和组合物
US10034945B2 (en) 2012-07-13 2018-07-31 Trustees Of Tufts College Silk powder compaction for production of constructs with high mechanical strength and stiffness
BR112015014969B1 (pt) 2012-12-21 2021-12-07 Corium, Inc Aparelho de microestruturas e método de fabricar um aparelho de microestruturas
EP2968887B1 (de) 2013-03-12 2022-05-04 Corium, Inc. Mikroprojektionsapplikatoren
US10195409B2 (en) 2013-03-15 2019-02-05 Corium International, Inc. Multiple impact microprojection applicators and methods of use
KR20210149207A (ko) 2013-03-15 2021-12-08 트러스티즈 오브 터프츠 칼리지 저분자량 실크 조성물 및 안정화 실크 조성물
CA2903763C (en) * 2013-03-15 2021-11-16 Corium International, Inc. Microarray with polymer-free microstructures, methods of making, and methods of use
US11376329B2 (en) 2013-03-15 2022-07-05 Trustees Of Tufts College Low molecular weight silk compositions and stabilizing silk compositions
CN105246458B (zh) 2013-03-15 2020-09-15 考里安公司 用于治疗剂递送的微阵列及其使用方法
WO2014176458A2 (en) 2013-04-24 2014-10-30 Trustees Of Tufts College Bioresorbable biopolymer anastomosis devices
EP3105339A1 (de) 2014-02-10 2016-12-21 Bio-E.R.G. S.r.l. Verfahren zur herstellung von dextran
EP3188714A1 (de) 2014-09-04 2017-07-12 Corium International, Inc. Mikrostrukturanordnung, verfahren zur herstellung und verfahren zur verwendung
WO2016100721A1 (en) 2014-12-17 2016-06-23 Tufts University Injectable, flexible hydroxyapatite-silk foams for osteochondral and dental repair
US10857093B2 (en) 2015-06-29 2020-12-08 Corium, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making
EP3865101A1 (de) 2015-07-20 2021-08-18 Tufts University Biologisch abbaubare paukenröhrchen aus seide
US10864299B2 (en) 2016-04-29 2020-12-15 Trustees Of Tufts College Artificial silk based innervated cornea
WO2018006037A1 (en) 2016-07-01 2018-01-04 Trustees Of Tufts College Innervated artificial skin
WO2018026853A1 (en) 2016-08-01 2018-02-08 Trustees Of Tufts College Biomimetic mechanical tension driven fabrication of nanofibrillar architecture
WO2018136754A1 (en) 2017-01-20 2018-07-26 Massachusetts Institute Of Technology Injectable polymer micro-depots for controlled local drug delivery
US11419947B2 (en) 2017-10-30 2022-08-23 Massachusetts Institute Of Technology Layer-by-layer nanoparticles for cytokine therapy in cancer treatment
US20210236644A1 (en) 2017-11-10 2021-08-05 Cocoon Biotech Inc. Ocular applications of silk-based products
KR102075596B1 (ko) * 2017-12-04 2020-02-10 이일훈 덱스트란 또는 폴록사머를 포함하는 관절 질환 또는 결체조직 질환 치료용 조성물
AU2020288624A1 (en) 2019-06-04 2022-02-03 Cocoon Biotech Inc. Silk-based products, formulations, and methods of use
KR102316719B1 (ko) * 2020-02-04 2021-10-25 메디슨파크 주식회사 덱스트란 또는 폴록사머를 포함하는 관절 질환 또는 결체조직 질환 치료용 조성물
KR102172290B1 (ko) * 2020-02-04 2020-10-30 메디슨파크 주식회사 덱스트란 또는 폴록사머를 포함하는 관절 질환 또는 결체조직 질환 치료용 조성물
KR102468374B1 (ko) * 2020-10-26 2022-11-17 메디슨파크 주식회사 덱스트란 또는 폴록사머를 포함하는 관절 질환 또는 결체조직 질환 치료용 조성물

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4758429A (en) * 1985-11-04 1988-07-19 Gordon Robert T Method for the treatment of arthritis and inflammatory joint diseases
DK505488D0 (da) * 1987-12-21 1988-09-09 Bar Shalom Daniel Middel og anvendelse af samme
DK110188D0 (da) * 1988-03-02 1988-03-02 Claus Selch Larsen High molecular weight prodrug derivatives of antiinflammatory drugs
JP2788340B2 (ja) * 1989-12-21 1998-08-20 株式会社ニッショー 炎症治療剤
WO1992013541A1 (de) * 1991-01-30 1992-08-20 Hoechst Aktiengesellschaft Die verwendung substituierter polysaccharide zur behandlung von degenerativen gelenkerkrankungen
AU652022B2 (en) * 1991-02-12 1994-08-11 C.R. Bard Inc. Injectable medical device

Also Published As

Publication number Publication date
WO1999049874A1 (en) 1999-10-07
ES2217741T3 (es) 2004-11-01
CA2326510C (en) 2007-06-12
AU2848299A (en) 1999-10-18
JP4511031B2 (ja) 2010-07-28
US5902800A (en) 1999-05-11
EP1066044A1 (de) 2001-01-10
DK1066044T3 (da) 2004-07-12
BR9909199A (pt) 2000-12-05
CA2326510A1 (en) 1999-10-07
MXPA00009159A (es) 2004-11-22
AU753124B2 (en) 2002-10-10
JP2002509890A (ja) 2002-04-02
EP1066044B1 (de) 2004-03-10
DE69915458D1 (de) 2004-04-15
DE69915458T2 (de) 2005-02-24

Similar Documents

Publication Publication Date Title
ATE261308T1 (de) Dextran formulierungen zur behandlung entzündlicher gelenkerkrankungen
PT1079806E (pt) Preparacoes para a aplicacao de anti-inflamatorios, especialmente, agentes anti-septicos e/ou agentes de promocao da cura de feridas, no tracto respiratorio superior e/ou no ouvido
TW262461B (de)
BRPI9908182B8 (pt) composições de proteína de matriz para cura de feridas
NO952863D0 (no) Fluoxetin-farmasöytiske sammensetninger
BR0112962A (pt) Composições farmacêuticas para o tratamento de condições inflamatórias e ulcerativas dolorosas de maioria das superfìcies epiteliais tais como mucosite, estomatite e sìndrome de behcet
SE0300010D0 (sv) Novel Compounds
ZA829046B (en) Pharmaceutically active phenylcarboxylic and derivatives
DE69905368T2 (de) Oxydiertes thymosin beta 4
BG101118A (en) Therapeutical compounds
AU2002231889A1 (en) Halogenated composition, method for preparing same and uses thereof
SE9804614A0 (en) New peptides and use thereof
HUP9602498A2 (hu) Antimikrobiális hatású gyógyászati készítmények
HUP0301506A3 (en) Pharmaceutical compositions for the treatment of painful, inflammatory and ulcerative conditions of moist epithelial surfaces such as mucositis, stomatitis and behcet's syndrome
ATE267816T1 (de) Tan-1057 derivate
GB0315632D0 (en) Pharmaceutical formulations
ATE316379T1 (de) Oxyhuminsäure und ihre verwendung zur behandlung von verschiedenenen störungen
TR200002847T2 (tr) Biçim VI 5, 6-dikloro-2-(izopropilamino) -1-(beta-L-ribofüranosil) -1H-benzimidazol.
WO2002000839A3 (en) Statement as to federally sponsored research
ATE255890T1 (de) Pantothensäure-enthaltende arzneimittel zur behandlung von entzündlichen gelenkserkrankungen
JO2370B1 (en) Pharmaceutical formulations for the treatment of painful, inflamed and ulcerated conditions of wet epithelial surfaces such as mucositis, stomatitis and Behçet syndrome
WO2000029433A3 (en) 12-25-kda bacterial proteins and their 116-58 kda polymers for use e.g. in anti-tumor vaccines
UA49889C2 (uk) Антибактеріальний препарат "бороцин"

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1066044

Country of ref document: EP