DK1066044T3 - Dextranformuleringer til behandling af inflammatoriske ledsygdomme - Google Patents

Dextranformuleringer til behandling af inflammatoriske ledsygdomme

Info

Publication number
DK1066044T3
DK1066044T3 DK99909118T DK99909118T DK1066044T3 DK 1066044 T3 DK1066044 T3 DK 1066044T3 DK 99909118 T DK99909118 T DK 99909118T DK 99909118 T DK99909118 T DK 99909118T DK 1066044 T3 DK1066044 T3 DK 1066044T3
Authority
DK
Denmark
Prior art keywords
dextran
treatment
molecular weight
joint diseases
inflammatory joint
Prior art date
Application number
DK99909118T
Other languages
English (en)
Inventor
June Ha Green
Peter B Buckley
Original Assignee
Glenpharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glenpharma filed Critical Glenpharma
Application granted granted Critical
Publication of DK1066044T3 publication Critical patent/DK1066044T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0009Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
    • C08B37/0021Dextran, i.e. (alpha-1,4)-D-glucan; Derivatives thereof, e.g. Sephadex, i.e. crosslinked dextran
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Rheumatology (AREA)
  • Polymers & Plastics (AREA)
  • Materials Engineering (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
DK99909118T 1998-03-27 1999-03-25 Dextranformuleringer til behandling af inflammatoriske ledsygdomme DK1066044T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/049,055 US5902800A (en) 1998-03-27 1998-03-27 Dextran formulations and method for treatment of inflammatory joint disorders

Publications (1)

Publication Number Publication Date
DK1066044T3 true DK1066044T3 (da) 2004-07-12

Family

ID=21957832

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99909118T DK1066044T3 (da) 1998-03-27 1999-03-25 Dextranformuleringer til behandling af inflammatoriske ledsygdomme

Country Status (12)

Country Link
US (1) US5902800A (da)
EP (1) EP1066044B1 (da)
JP (1) JP4511031B2 (da)
AT (1) ATE261308T1 (da)
AU (1) AU753124B2 (da)
BR (1) BR9909199A (da)
CA (1) CA2326510C (da)
DE (1) DE69915458T2 (da)
DK (1) DK1066044T3 (da)
ES (1) ES2217741T3 (da)
MX (1) MXPA00009159A (da)
WO (1) WO1999049874A1 (da)

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DE19908441C1 (de) * 1999-02-26 2000-08-31 Chakravarty Adusumalli Injektionslösung zur Behandlung von Arthrosen
US6800298B1 (en) * 2000-05-11 2004-10-05 Clemson University Biological lubricant composition and method of applying lubricant composition
US7387796B2 (en) * 2002-01-30 2008-06-17 Hebert Rolland F Stable compositions of S-adenosyl-l-methionine with dextran
AU2003249366A1 (en) 2002-06-24 2004-01-06 Tufts University Silk biomaterials and methods of use thereof
CA2562415C (en) 2003-04-10 2015-10-27 Tufts University Concentrated aqueous silk fibroin solutions free of organic solvents and uses thereof
US8178656B2 (en) 2004-06-11 2012-05-15 Trustees Of Tufts College Silk-based drug delivery system
US20100028451A1 (en) 2006-09-26 2010-02-04 Trustees Of Tufts College Silk microspheres for encapsulation and controlled release
WO2008106485A2 (en) 2007-02-27 2008-09-04 Trustees Of Tufts College Tissue-engineered silk organs
WO2008130587A2 (en) 2007-04-16 2008-10-30 Corium International, Inc. Solvent-cast microneedle arrays containing active
US9808557B2 (en) 2007-08-10 2017-11-07 Trustees Of Tufts College Tubular silk compositions and methods of use thereof
HUE050574T2 (hu) * 2009-09-23 2020-12-28 Glenpharma Ab Készítmények és módszerek kötõszövet gyógyulás indukálására vagy elõsegítésére
US9687641B2 (en) 2010-05-04 2017-06-27 Corium International, Inc. Method and device for transdermal delivery of parathyroid hormone using a microprojection array
WO2011160146A1 (en) 2010-06-23 2011-12-29 Croma-Pharma Gesellschaft M.B.H. Pharmaceutical preparation containing dextran and sodium hyaluronate for the treatment of joint disorders
GB201020300D0 (en) * 2010-11-30 2011-01-12 Vitrolife Sweden Ab Product
WO2012145652A1 (en) 2011-04-20 2012-10-26 Trustees Of Tufts College Dynamic silk coatings for implantable devices
JP2015510818A (ja) 2012-03-20 2015-04-13 トラスティーズ オブ タフツ カレッジ 薬物送達のための絹リザーバー
WO2013155404A1 (en) 2012-04-13 2013-10-17 Trustees Of Tufts College Methods and compositions for preparing a silk microsphere
US10034945B2 (en) 2012-07-13 2018-07-31 Trustees Of Tufts College Silk powder compaction for production of constructs with high mechanical strength and stiffness
MX2015008157A (es) 2012-12-21 2016-02-22 Corium Int Inc Microarreglo para la entrega de agente terapeutico y metodos de uso.
BR112015022253B1 (pt) 2013-03-12 2022-03-15 Corium, Inc Aplicador de microprojeções
AU2014237279B2 (en) 2013-03-15 2018-11-22 Corium Pharma Solutions, Inc. Microarray with polymer-free microstructures, methods of making, and methods of use
US11376329B2 (en) 2013-03-15 2022-07-05 Trustees Of Tufts College Low molecular weight silk compositions and stabilizing silk compositions
BR112015022625B1 (pt) 2013-03-15 2023-01-31 Corium, Inc Aparelho de microestrutura para entrega de agente terapêutico
WO2014145002A2 (en) 2013-03-15 2014-09-18 Kluge Jonathan A Low molecular weight silk compositions and stabilizing silk compositions
CA2903459C (en) 2013-03-15 2024-02-20 Corium International, Inc. Multiple impact microprojection applicators and methods of use
US10285702B2 (en) 2013-04-24 2019-05-14 Trustees Of Tufts College Bioresorbable biopolymer anastomosis devices
JP6527888B2 (ja) 2014-02-10 2019-06-05 バイオ−エ・エッレ・ジ・エッセ・エッレ・エッレ デキストランの製造方法
WO2016036866A1 (en) 2014-09-04 2016-03-10 Corium International, Inc. Microstructure array, methods of making, and methods of use
US10758645B2 (en) 2014-12-17 2020-09-01 Tufts University Injectable, flexible hydroxyapatite-silk foams for osteochondral and dental repair
US10857093B2 (en) 2015-06-29 2020-12-08 Corium, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making
CA2995233C (en) 2015-07-20 2024-01-02 Tufts University Biodegradable silk ear tubes
US10864299B2 (en) 2016-04-29 2020-12-15 Trustees Of Tufts College Artificial silk based innervated cornea
WO2018006037A1 (en) 2016-07-01 2018-01-04 Trustees Of Tufts College Innervated artificial skin
US11248313B2 (en) 2016-08-01 2022-02-15 Trustees Of Tufts College Biomimetic mechanical tension driven fabrication of nanofibrillar architecture
US20200000713A1 (en) 2017-01-20 2020-01-02 Massachusetts Institute Of Technology Injectable polymer micro-depots for controlled local drug delivery
WO2019089567A1 (en) 2017-10-30 2019-05-09 Massachusetts Institute Of Technology Layer-by-layer nanoparticles for cytokine therapy in cancer treatment
US20210236644A1 (en) 2017-11-10 2021-08-05 Cocoon Biotech Inc. Ocular applications of silk-based products
KR102075596B1 (ko) * 2017-12-04 2020-02-10 이일훈 덱스트란 또는 폴록사머를 포함하는 관절 질환 또는 결체조직 질환 치료용 조성물
US12018315B2 (en) 2019-05-30 2024-06-25 Massachusetts Institute Of Technology Peptide nucleic acid functionalized hydrogel microneedles for sampling and detection of interstitial fluid nucleic acids
WO2020247594A1 (en) 2019-06-04 2020-12-10 Cocoon Biotech Inc. Silk-based products, formulations, and methods of use
KR102172290B1 (ko) * 2020-02-04 2020-10-30 메디슨파크 주식회사 덱스트란 또는 폴록사머를 포함하는 관절 질환 또는 결체조직 질환 치료용 조성물
KR102316719B1 (ko) * 2020-02-04 2021-10-25 메디슨파크 주식회사 덱스트란 또는 폴록사머를 포함하는 관절 질환 또는 결체조직 질환 치료용 조성물
KR102468374B1 (ko) * 2020-10-26 2022-11-17 메디슨파크 주식회사 덱스트란 또는 폴록사머를 포함하는 관절 질환 또는 결체조직 질환 치료용 조성물

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* Cited by examiner, † Cited by third party
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US4758429A (en) * 1985-11-04 1988-07-19 Gordon Robert T Method for the treatment of arthritis and inflammatory joint diseases
DK505488D0 (da) * 1987-12-21 1988-09-09 Bar Shalom Daniel Middel og anvendelse af samme
DK110188D0 (da) * 1988-03-02 1988-03-02 Claus Selch Larsen High molecular weight prodrug derivatives of antiinflammatory drugs
JP2788340B2 (ja) * 1989-12-21 1998-08-20 株式会社ニッショー 炎症治療剤
AU1154992A (en) * 1991-01-30 1992-09-07 Hoechst Aktiengesellschaft Use of substituted polysaccharides for the treatment of degenerative articular ailments
CA2060223C (en) * 1991-02-12 1999-07-20 Clarence C. Lee Injectable medical lubricating fluid composition and method of use

Also Published As

Publication number Publication date
US5902800A (en) 1999-05-11
BR9909199A (pt) 2000-12-05
CA2326510A1 (en) 1999-10-07
WO1999049874A1 (en) 1999-10-07
EP1066044A1 (en) 2001-01-10
DE69915458T2 (de) 2005-02-24
MXPA00009159A (es) 2004-11-22
ATE261308T1 (de) 2004-03-15
AU2848299A (en) 1999-10-18
AU753124B2 (en) 2002-10-10
ES2217741T3 (es) 2004-11-01
EP1066044B1 (en) 2004-03-10
DE69915458D1 (de) 2004-04-15
JP2002509890A (ja) 2002-04-02
JP4511031B2 (ja) 2010-07-28
CA2326510C (en) 2007-06-12

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