ATE258T1 - Verfahren zur herstellung von 7,8-dichlor-1,2,3,4-tetrahydroisochinolin und zwischenprodukte. - Google Patents
Verfahren zur herstellung von 7,8-dichlor-1,2,3,4-tetrahydroisochinolin und zwischenprodukte.Info
- Publication number
- ATE258T1 ATE258T1 AT79102847T AT79102847T ATE258T1 AT E258 T1 ATE258 T1 AT E258T1 AT 79102847 T AT79102847 T AT 79102847T AT 79102847 T AT79102847 T AT 79102847T AT E258 T1 ATE258 T1 AT E258T1
- Authority
- AT
- Austria
- Prior art keywords
- tetrahydroisochinoline
- dichloro
- manufacture
- intermediate products
- products
- Prior art date
Links
- WFPUBEDBBOGGIQ-UHFFFAOYSA-N 7,8-dichloro-1,2,3,4-tetrahydroisoquinoline Chemical compound C1CNCC2=C(Cl)C(Cl)=CC=C21 WFPUBEDBBOGGIQ-UHFFFAOYSA-N 0.000 title 1
- 239000013067 intermediate product Substances 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/932,586 US4251660A (en) | 1978-08-10 | 1978-08-10 | Method for preparing tetrahydroisoquinolines |
| EP79102847A EP0008405B1 (en) | 1978-08-10 | 1979-08-07 | Method for preparing 7,8-dichloro-1,2,3,4-tetrahydroisoquinoline and n-chloroethyl-, n-bromoethyl- or n-hydroxyethyl-2,3-dichlorobenzylamine intermediate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE258T1 true ATE258T1 (de) | 1981-10-15 |
Family
ID=25462546
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT79102847T ATE258T1 (de) | 1978-08-10 | 1979-08-07 | Verfahren zur herstellung von 7,8-dichlor-1,2,3,4-tetrahydroisochinolin und zwischenprodukte. |
Country Status (29)
| Country | Link |
|---|---|
| US (1) | US4251660A (cs) |
| EP (1) | EP0008405B1 (cs) |
| JP (1) | JPS5524196A (cs) |
| AR (1) | AR220218A1 (cs) |
| AT (1) | ATE258T1 (cs) |
| AU (1) | AU522843B2 (cs) |
| BG (1) | BG32714A3 (cs) |
| CA (1) | CA1130290A (cs) |
| CS (1) | CS226006B2 (cs) |
| DD (1) | DD145532A5 (cs) |
| DE (1) | DE2961141D1 (cs) |
| DK (1) | DK330579A (cs) |
| ES (1) | ES483151A1 (cs) |
| FI (1) | FI65062C (cs) |
| GR (1) | GR69853B (cs) |
| HU (1) | HU178110B (cs) |
| IE (1) | IE48618B1 (cs) |
| IL (1) | IL57980A (cs) |
| IN (1) | IN152421B (cs) |
| IT (1) | IT1227791B (cs) |
| MX (1) | MX5581E (cs) |
| NO (1) | NO153807C (cs) |
| NZ (1) | NZ191227A (cs) |
| PH (1) | PH24441A (cs) |
| PL (1) | PL217684A1 (cs) |
| PT (1) | PT70029A (cs) |
| RO (1) | RO78160A (cs) |
| SU (1) | SU860698A3 (cs) |
| ZA (1) | ZA793308B (cs) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0161350A1 (en) * | 1981-11-27 | 1985-11-21 | Smithkline Beckman Corporation | Process for preparing benzazepines |
| US4541954A (en) * | 1984-09-05 | 1985-09-17 | Smithkline Beckman Corporation | Method for preparing 6-chloro-N-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2771468A (en) * | 1954-02-19 | 1956-11-20 | Sterling Drug Inc | 4-aralkyl-3-morpholones, 4-aralkyl-3-homomorpholones and their preparation |
| US3947456A (en) * | 1970-01-06 | 1976-03-30 | Hoffman-La Roche Inc. | Substituted 4-phenyl isoquinolines |
| US3752892A (en) * | 1970-03-11 | 1973-08-14 | Ciba Geigy Corp | Anorexigenic tetrahydrobenzazepine derivative method and composition thereof |
-
1978
- 1978-08-10 US US05/932,586 patent/US4251660A/en not_active Expired - Lifetime
-
1979
- 1979-06-27 IN IN470/DEL/79A patent/IN152421B/en unknown
- 1979-07-03 ZA ZA793308A patent/ZA793308B/xx unknown
- 1979-08-02 IT IT7924894A patent/IT1227791B/it active
- 1979-08-03 CA CA333,200A patent/CA1130290A/en not_active Expired
- 1979-08-03 AR AR277592A patent/AR220218A1/es active
- 1979-08-03 PH PH22859A patent/PH24441A/en unknown
- 1979-08-03 AU AU49547/79A patent/AU522843B2/en not_active Ceased
- 1979-08-06 GR GR59778A patent/GR69853B/el unknown
- 1979-08-06 ES ES483151A patent/ES483151A1/es not_active Expired
- 1979-08-06 PT PT70029A patent/PT70029A/pt unknown
- 1979-08-06 IL IL57980A patent/IL57980A/xx unknown
- 1979-08-06 FI FI792436A patent/FI65062C/fi not_active IP Right Cessation
- 1979-08-06 NZ NZ191227A patent/NZ191227A/xx unknown
- 1979-08-07 JP JP10115279A patent/JPS5524196A/ja active Pending
- 1979-08-07 DE DE7979102847T patent/DE2961141D1/de not_active Expired
- 1979-08-07 DK DK330579A patent/DK330579A/da not_active Application Discontinuation
- 1979-08-07 EP EP79102847A patent/EP0008405B1/en not_active Expired
- 1979-08-07 AT AT79102847T patent/ATE258T1/de not_active IP Right Cessation
- 1979-08-08 RO RO7998406A patent/RO78160A/ro unknown
- 1979-08-09 HU HU79SI1715A patent/HU178110B/hu unknown
- 1979-08-09 CS CS795460A patent/CS226006B2/cs unknown
- 1979-08-09 NO NO792601A patent/NO153807C/no unknown
- 1979-08-09 IE IE1534/79A patent/IE48618B1/en unknown
- 1979-08-09 DD DD79214893A patent/DD145532A5/de unknown
- 1979-08-10 BG BG044609A patent/BG32714A3/xx unknown
- 1979-08-10 MX MX798312U patent/MX5581E/es unknown
- 1979-08-10 PL PL21768479A patent/PL217684A1/xx unknown
- 1979-08-10 SU SU792798064A patent/SU860698A3/ru active
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |