IL57980A - Method for preparing 7,8-dichlorotetrahydroisoquinoline hydrochloride and n-hydroxyethyl-n-2,3-dichlorobenzylamine as intermediate therefor - Google Patents

Method for preparing 7,8-dichlorotetrahydroisoquinoline hydrochloride and n-hydroxyethyl-n-2,3-dichlorobenzylamine as intermediate therefor

Info

Publication number
IL57980A
IL57980A IL57980A IL5798079A IL57980A IL 57980 A IL57980 A IL 57980A IL 57980 A IL57980 A IL 57980A IL 5798079 A IL5798079 A IL 5798079A IL 57980 A IL57980 A IL 57980A
Authority
IL
Israel
Prior art keywords
dichlorotetrahydroisoquinoline
dichlorobenzylamine
hydrochloride
hydroxyethyl
preparing
Prior art date
Application number
IL57980A
Other languages
English (en)
Other versions
IL57980A0 (en
Original Assignee
Smithkline Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Corp filed Critical Smithkline Corp
Publication of IL57980A0 publication Critical patent/IL57980A0/xx
Publication of IL57980A publication Critical patent/IL57980A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL57980A 1978-08-10 1979-08-06 Method for preparing 7,8-dichlorotetrahydroisoquinoline hydrochloride and n-hydroxyethyl-n-2,3-dichlorobenzylamine as intermediate therefor IL57980A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/932,586 US4251660A (en) 1978-08-10 1978-08-10 Method for preparing tetrahydroisoquinolines

Publications (2)

Publication Number Publication Date
IL57980A0 IL57980A0 (en) 1979-12-30
IL57980A true IL57980A (en) 1984-08-31

Family

ID=25462546

Family Applications (1)

Application Number Title Priority Date Filing Date
IL57980A IL57980A (en) 1978-08-10 1979-08-06 Method for preparing 7,8-dichlorotetrahydroisoquinoline hydrochloride and n-hydroxyethyl-n-2,3-dichlorobenzylamine as intermediate therefor

Country Status (29)

Country Link
US (1) US4251660A (xx)
EP (1) EP0008405B1 (xx)
JP (1) JPS5524196A (xx)
AR (1) AR220218A1 (xx)
AT (1) ATE258T1 (xx)
AU (1) AU522843B2 (xx)
BG (1) BG32714A3 (xx)
CA (1) CA1130290A (xx)
CS (1) CS226006B2 (xx)
DD (1) DD145532A5 (xx)
DE (1) DE2961141D1 (xx)
DK (1) DK330579A (xx)
ES (1) ES483151A1 (xx)
FI (1) FI65062C (xx)
GR (1) GR69853B (xx)
HU (1) HU178110B (xx)
IE (1) IE48618B1 (xx)
IL (1) IL57980A (xx)
IN (1) IN152421B (xx)
IT (1) IT1227791B (xx)
MX (1) MX5581E (xx)
NO (1) NO153807C (xx)
NZ (1) NZ191227A (xx)
PH (1) PH24441A (xx)
PL (1) PL217684A1 (xx)
PT (1) PT70029A (xx)
RO (1) RO78160A (xx)
SU (1) SU860698A3 (xx)
ZA (1) ZA793308B (xx)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0161350A1 (en) * 1981-11-27 1985-11-21 Smithkline Beckman Corporation Process for preparing benzazepines
US4541954A (en) * 1984-09-05 1985-09-17 Smithkline Beckman Corporation Method for preparing 6-chloro-N-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2771468A (en) * 1954-02-19 1956-11-20 Sterling Drug Inc 4-aralkyl-3-morpholones, 4-aralkyl-3-homomorpholones and their preparation
US3947456A (en) * 1970-01-06 1976-03-30 Hoffman-La Roche Inc. Substituted 4-phenyl isoquinolines
US3752892A (en) * 1970-03-11 1973-08-14 Ciba Geigy Corp Anorexigenic tetrahydrobenzazepine derivative method and composition thereof

Also Published As

Publication number Publication date
PT70029A (en) 1979-09-01
CS226006B2 (en) 1984-03-19
NO792601L (no) 1980-02-12
AU4954779A (en) 1980-02-14
FI65062C (fi) 1984-03-12
NO153807C (no) 1986-05-28
EP0008405A3 (en) 1980-04-30
ATE258T1 (de) 1981-10-15
GR69853B (xx) 1982-07-19
DE2961141D1 (en) 1981-12-10
AR220218A1 (es) 1980-10-15
IT1227791B (it) 1991-05-07
RO78160A (ro) 1982-02-01
EP0008405A2 (en) 1980-03-05
IE791534L (en) 1980-02-10
ZA793308B (en) 1980-09-24
FI792436A (fi) 1980-02-11
BG32714A3 (en) 1982-09-15
CA1130290A (en) 1982-08-24
ES483151A1 (es) 1980-04-16
JPS5524196A (en) 1980-02-21
IL57980A0 (en) 1979-12-30
EP0008405B1 (en) 1981-09-30
IE48618B1 (en) 1985-03-20
IT7924894A0 (it) 1979-08-02
NO153807B (no) 1986-02-17
DD145532A5 (de) 1980-12-17
AU522843B2 (en) 1982-07-01
MX5581E (es) 1983-10-26
PH24441A (en) 1990-06-25
PL217684A1 (xx) 1980-06-16
IN152421B (xx) 1984-01-07
DK330579A (da) 1980-02-11
SU860698A3 (ru) 1981-08-30
US4251660A (en) 1981-02-17
HU178110B (en) 1982-03-28
NZ191227A (en) 1981-10-19
FI65062B (fi) 1983-11-30

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