ATE258552T1 - Oxazolidinon-derivate als antibiotika, verfahren zu ihrer herstellung und diese derivate enthaltende pharmazeutische zusammensetzungen - Google Patents

Oxazolidinon-derivate als antibiotika, verfahren zu ihrer herstellung und diese derivate enthaltende pharmazeutische zusammensetzungen

Info

Publication number
ATE258552T1
ATE258552T1 AT99925181T AT99925181T ATE258552T1 AT E258552 T1 ATE258552 T1 AT E258552T1 AT 99925181 T AT99925181 T AT 99925181T AT 99925181 T AT99925181 T AT 99925181T AT E258552 T1 ATE258552 T1 AT E258552T1
Authority
AT
Austria
Prior art keywords
derivatives
antibiotics
production
pharmaceutical compositions
compositions containing
Prior art date
Application number
AT99925181T
Other languages
English (en)
Inventor
Michael Barry Gravestock
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Application granted granted Critical
Publication of ATE258552T1 publication Critical patent/ATE258552T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT99925181T 1998-06-05 1999-06-03 Oxazolidinon-derivate als antibiotika, verfahren zu ihrer herstellung und diese derivate enthaltende pharmazeutische zusammensetzungen ATE258552T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9812019.9A GB9812019D0 (en) 1998-06-05 1998-06-05 Chemical compounds
PCT/GB1999/001737 WO1999064416A2 (en) 1998-06-05 1999-06-03 Oxazolidinone derivatives, process for their preparation and pharmaceutical compositions containing them

Publications (1)

Publication Number Publication Date
ATE258552T1 true ATE258552T1 (de) 2004-02-15

Family

ID=10833201

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99925181T ATE258552T1 (de) 1998-06-05 1999-06-03 Oxazolidinon-derivate als antibiotika, verfahren zu ihrer herstellung und diese derivate enthaltende pharmazeutische zusammensetzungen

Country Status (16)

Country Link
EP (2) EP1357122A3 (de)
JP (1) JP2002517497A (de)
KR (1) KR20010052590A (de)
CN (1) CN1304410A (de)
AT (1) ATE258552T1 (de)
AU (1) AU753865B2 (de)
BR (1) BR9910915A (de)
CA (1) CA2332831A1 (de)
DE (1) DE69914478T2 (de)
GB (1) GB9812019D0 (de)
HU (1) HUP0103404A3 (de)
IL (1) IL140085A0 (de)
NO (1) NO20006149L (de)
NZ (1) NZ507973A (de)
WO (1) WO1999064416A2 (de)
ZA (1) ZA200006697B (de)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6608081B2 (en) 1999-08-12 2003-08-19 Ortho-Mcneil Pharmaceutical, Inc. Bicyclic heterocyclic substituted phenyl oxazolidinone antibacterials, and related compositions and methods
GB9928568D0 (en) 1999-12-03 2000-02-02 Zeneca Ltd Chemical compounds
PE20010851A1 (es) * 1999-12-14 2001-08-17 Upjohn Co Esteres del acido benzoico de oxazolidinonas que tienen un substituyente hidroxiacetilpiperazina
GB0009803D0 (en) * 2000-04-25 2000-06-07 Astrazeneca Ab Chemical compounds
PE20020689A1 (es) * 2000-11-17 2002-08-03 Upjohn Co Oxazolidinonas con un heterociclo de 6 o 7 miembros unidos con enlace anular al benceno
PE20030044A1 (es) 2000-11-17 2003-02-09 Upjohn Co Isoxazolinonas biciclicas de formula i
AU2002256995A1 (en) 2001-02-07 2002-08-28 Ortho-Mcneil Pharmaceutical, Inc. Pyridoarylphenyl oxazolidinone antibacterials, and related compositions and methods
IL160739A0 (en) 2001-09-11 2004-08-31 Astrazeneca Ab Oxazolidinone and/or isoxazoline as antibacterial agents
WO2003035648A1 (en) * 2001-10-25 2003-05-01 Astrazeneca Ab Aryl substituted oxazolidinones with antibacterial activity
US7022705B2 (en) 2001-10-25 2006-04-04 Astrazeneca Ab Isoxazoline derivatives useful as antimicrobials
KR20040086465A (ko) 2002-02-28 2004-10-08 아스트라제네카 아베 화합물
MXPA04008312A (es) 2002-02-28 2004-11-26 Astrazeneca Ab Derivados de 3-cilil-5-(anillo de 5 miembros que contienen nitrogeno)-metil-oxazolidinona y sus uso como agentes antibacterianos.
AR043050A1 (es) 2002-09-26 2005-07-13 Rib X Pharmaceuticals Inc Compuestos heterociclicos bifuncionales y metodos para preparar y usar los mismos
US7012088B2 (en) * 2003-02-24 2006-03-14 Pharmacia & Upjohn Company Indolone oxazolidinones and derivatives thereof
GB0306358D0 (en) * 2003-03-20 2003-04-23 Astrazeneca Ab Chemical compounds
US8324398B2 (en) 2003-06-03 2012-12-04 Rib-X Pharmaceuticals, Inc. Process for the synthesis of biaryl oxazolidinones
AU2004267007C1 (en) 2003-06-03 2010-04-29 Melinta Subsidiary Corp. Biaryl heterocyclic compounds and methods of making and using the same
US7129259B2 (en) 2003-12-17 2006-10-31 Rib-X Pharmaceuticals, Inc. Halogenated biaryl heterocyclic compounds and methods of making and using the same
EP1723159B1 (de) 2004-02-27 2019-06-12 Melinta Therapeutics, Inc. Makrozyklische verbindungen, deren herstellung und verwendung
MX2007001526A (es) * 2004-08-06 2007-03-27 Pharmacia & Upjohn Co Llc Oxazolidinonas que contienen oxindoles como agentes antibacterianos.
AR051026A1 (es) 2004-09-20 2006-12-13 Xenon Pharmaceuticals Inc Derivados heterociclicos y su uso como inhibidores de la estearoil-coa desaturasa
US8071603B2 (en) 2004-09-20 2011-12-06 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as stearoyl-CoA desaturase inhibitors
EP2316458A1 (de) 2004-09-20 2011-05-04 Xenon Pharmaceuticals Inc. Pyridazin-Derivate zur Verhinderung menschlicher Stearoyl-coa-desaturas
AU2005286647A1 (en) 2004-09-20 2006-03-30 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as stearoyl-CoA desaturase inhibitors
WO2006101521A2 (en) 2004-09-20 2006-09-28 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as stearoyl-coa desaturase inhibitors
AU2005286846A1 (en) 2004-09-20 2006-03-30 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as therapeutic agents
US7951805B2 (en) 2004-09-20 2011-05-31 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as mediators of stearoyl-CoA desaturase
WO2006043121A1 (en) * 2004-10-20 2006-04-27 Ranbaxy Laboratories Limited Oxazolidinone derivatives as antimicrobials
JP2009513563A (ja) 2005-06-03 2009-04-02 ゼノン・ファーマシューティカルズ・インコーポレイテッド ヒトのステアロイル−ＣｏＡデサチュラーゼ阻害剤としてのアミノチアゾール誘導体
DE602006019870D1 (de) 2005-06-08 2011-03-10 Rib X Pharmaceuticals Inc Verfahren zur synthese von triazolen
US7618989B2 (en) 2006-08-15 2009-11-17 Wyeth Tricyclic oxazolidone derivatives useful as PR modulators
US7652018B2 (en) 2006-08-15 2010-01-26 Wyeth Llc Imidazolidin-2-one derivatives useful as PR modulators
US7538107B2 (en) 2006-08-15 2009-05-26 Wyeth Oxazinan-2-one derivatives useful as PR modulators
US7649007B2 (en) 2006-08-15 2010-01-19 Wyeth Llc Oxazolidine derivatives as PR modulators
CN101798302B (zh) 2009-02-06 2014-11-05 上海盟科药业有限公司 抗生素类药物1-(邻-氟苯基)二氢吡啶酮的合成及生产的方法和工艺
WO2013182070A1 (zh) * 2012-06-08 2013-12-12 四川贝力克生物技术有限责任公司 一种用于预防或治疗分支杆菌疾病的药物

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2112129C (en) * 1992-04-30 1997-10-07 Shingo Yano Oxazolidine derivative and pharmaceutically acceptable salt thereof
SK283420B6 (sk) * 1992-05-08 2003-07-01 Pharmacia & Upjohn Company Antimikrobiálne oxazolidinóny obsahujúce substituované diazínové skupiny
AU668818B2 (en) * 1993-04-07 1996-05-16 Taiho Pharmaceutical Co., Ltd. Thiazolidine derivative and pharmaceutical composition containing the same
DE4332384A1 (de) * 1993-09-23 1995-03-30 Merck Patent Gmbh Adhäsionsrezeptor-Antagonisten III
DK0710657T3 (da) * 1994-11-02 1999-05-25 Merck Patent Gmbh Adhæsionsreceptor-antagonister
DK0844874T3 (da) * 1995-08-14 2006-01-16 Scripps Research Inst Fremgangsmåder og sammensætninger egnet til inhibering af alfa v beta 5-medieret angiogenese
FI980452A7 (fi) * 1995-09-01 1998-02-27 Upjohn Co Fenyylioksatsolidinoneja, jotka ovat liittyneet C-C-sidoksella 4-8-jäs enisiin heterosyklisiin renkaisiin

Also Published As

Publication number Publication date
NZ507973A (en) 2003-10-31
EP1357122A3 (de) 2003-12-10
AU4156599A (en) 1999-12-30
NO20006149D0 (no) 2000-12-04
EP1082322A2 (de) 2001-03-14
KR20010052590A (ko) 2001-06-25
IL140085A0 (en) 2002-02-10
DE69914478D1 (de) 2004-03-04
ZA200006697B (en) 2002-02-18
NO20006149L (no) 2001-02-02
BR9910915A (pt) 2001-03-06
AU753865B2 (en) 2002-10-31
DE69914478T2 (de) 2004-11-11
GB9812019D0 (en) 1998-07-29
HUP0103404A2 (hu) 2002-05-29
HUP0103404A3 (en) 2002-08-28
EP1082322B1 (de) 2004-01-28
CN1304410A (zh) 2001-07-18
WO1999064416A3 (en) 2000-01-27
WO1999064416A2 (en) 1999-12-16
CA2332831A1 (en) 1999-12-16
JP2002517497A (ja) 2002-06-18
EP1357122A2 (de) 2003-10-29

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