BR9910915A - Composto, processos para preparar um composto e para produzir um efeito antibacteriano em um animal de sangue quente, uso de um composto, e, composição farmacêutica - Google Patents

Composto, processos para preparar um composto e para produzir um efeito antibacteriano em um animal de sangue quente, uso de um composto, e, composição farmacêutica

Info

Publication number
BR9910915A
BR9910915A BR9910915-8A BR9910915A BR9910915A BR 9910915 A BR9910915 A BR 9910915A BR 9910915 A BR9910915 A BR 9910915A BR 9910915 A BR9910915 A BR 9910915A
Authority
BR
Brazil
Prior art keywords
compound
processes
pharmaceutical composition
antibacterial effect
warm
Prior art date
Application number
BR9910915-8A
Other languages
English (en)
Inventor
Michael Barry Gravestock
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of BR9910915A publication Critical patent/BR9910915A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

"COMPOSTO, PROCESSOS PARA PREPARAR UM COMPOSTO E PARA PRODUZIR UM EFEITO ANTIBACTERIANO EM UM ANIMAL DE SANGUE QUENTE, USO DE UM COMPOSTO, E, COMPOSIçãO FARMACêUTICA". São descritos compostos de fórmula (I): ou um seu sal farmaceuticamente aceitável ou um éster hidrolisável in vivo, em que, por exemplo, X é -O- ou -S-; HET é um anel heteroarila de 6-membros ligado-C, contendo 1 ou 2 N átomos; Q é selecionado de, por exemplo, (Q1) e (Q2); R² e R³ são independentemente hidrogênio ou fluoro; T é selecionado de uma faixa de grupos, por exemplo, um sistema de anéis heteroarila de 5-membros N-ligado (totalmente insaturado) ou um grupo 3,6-diidro-(2H)-piran-4-ila ou um grupo piperazino 4-substituído; são úteis como agentes antibactericanos; e processos para sua manufatura e composições farmacêuticas contendo-os.
BR9910915-8A 1998-06-05 1999-06-03 Composto, processos para preparar um composto e para produzir um efeito antibacteriano em um animal de sangue quente, uso de um composto, e, composição farmacêutica BR9910915A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9812019.9A GB9812019D0 (en) 1998-06-05 1998-06-05 Chemical compounds
PCT/GB1999/001737 WO1999064416A2 (en) 1998-06-05 1999-06-03 Oxazolidinone derivatives, process for their preparation and pharmaceutical compositions containing them

Publications (1)

Publication Number Publication Date
BR9910915A true BR9910915A (pt) 2001-03-06

Family

ID=10833201

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9910915-8A BR9910915A (pt) 1998-06-05 1999-06-03 Composto, processos para preparar um composto e para produzir um efeito antibacteriano em um animal de sangue quente, uso de um composto, e, composição farmacêutica

Country Status (16)

Country Link
EP (2) EP1357122A3 (pt)
JP (1) JP2002517497A (pt)
KR (1) KR20010052590A (pt)
CN (1) CN1304410A (pt)
AT (1) ATE258552T1 (pt)
AU (1) AU753865B2 (pt)
BR (1) BR9910915A (pt)
CA (1) CA2332831A1 (pt)
DE (1) DE69914478T2 (pt)
GB (1) GB9812019D0 (pt)
HU (1) HUP0103404A3 (pt)
IL (1) IL140085A0 (pt)
NO (1) NO20006149L (pt)
NZ (1) NZ507973A (pt)
WO (1) WO1999064416A2 (pt)
ZA (1) ZA200006697B (pt)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6608081B2 (en) 1999-08-12 2003-08-19 Ortho-Mcneil Pharmaceutical, Inc. Bicyclic heterocyclic substituted phenyl oxazolidinone antibacterials, and related compositions and methods
PE20010851A1 (es) * 1999-12-14 2001-08-17 Upjohn Co Esteres del acido benzoico de oxazolidinonas que tienen un substituyente hidroxiacetilpiperazina
GB0009803D0 (en) * 2000-04-25 2000-06-07 Astrazeneca Ab Chemical compounds
PE20020689A1 (es) * 2000-11-17 2002-08-03 Upjohn Co Oxazolidinonas con un heterociclo de 6 o 7 miembros unidos con enlace anular al benceno
PE20030044A1 (es) 2000-11-17 2003-02-09 Upjohn Co Isoxazolinonas biciclicas de formula i
JP2004518724A (ja) * 2001-02-07 2004-06-24 オーソーマクニール ファーマシューティカル， インコーポレイテッド ピリドアリールフェニル・オキサゾリジノン抗菌剤、および関連の組成物および方法
SI1427711T1 (sl) 2001-09-11 2005-12-31 Astrazeneca Ab Oksazolidinonski in/ali izoksazolinski derivati kot antibakterijska sredstva
EP1443930A1 (en) 2001-10-25 2004-08-11 AstraZeneca AB Isoxazoline derivatives useful as antimicrobials
US20050043374A1 (en) * 2001-10-25 2005-02-24 Gravestock Michael Barry Aryl substituted oxazolidinones with antibacterial activity
PL372191A1 (en) 2002-02-28 2005-07-11 Astrazeneca Ab 3-cyclyl-5-(nitrogen-containing 5-membered ring) methyl-oxazolidinone derivatives and their use as antibacterial agents
MXPA04008273A (es) 2002-02-28 2004-11-10 Astrazeneca Ab Derivados de oxazolidinona, procesos para su preparacion, y composiciones farmaceuticas que los contienen.
TW200420573A (en) 2002-09-26 2004-10-16 Rib X Pharmaceuticals Inc Bifunctional heterocyclic compounds and methods of making and using same
US7012088B2 (en) 2003-02-24 2006-03-14 Pharmacia & Upjohn Company Indolone oxazolidinones and derivatives thereof
GB0306358D0 (en) * 2003-03-20 2003-04-23 Astrazeneca Ab Chemical compounds
US8324398B2 (en) 2003-06-03 2012-12-04 Rib-X Pharmaceuticals, Inc. Process for the synthesis of biaryl oxazolidinones
JP5043428B2 (ja) 2003-06-03 2012-10-10 リブ−エックス ファーマシューティカルズ，インコーポレイテッド ビアリール複素環式化合物ならびにその製造および使用方法
TW200526649A (en) 2003-12-17 2005-08-16 Rib X Pharmaceuticals Inc Halogenated biaryl heterocyclic compounds and methods of making and using the same
WO2005085266A2 (en) 2004-02-27 2005-09-15 Rib-X Pharmaceuticals, Inc. Macrocyclic compounds and methods of making and using the same
EP1781643A1 (en) * 2004-08-06 2007-05-09 Pharmacia & Upjohn Company LLC Oxindole oxazolidinones as antibacterial agents
AR051202A1 (es) 2004-09-20 2006-12-27 Xenon Pharmaceuticals Inc Derivados heterociclicos y su uso como inhibidores de la estearoil-coa desaturasa
CN101083994A (zh) 2004-09-20 2007-12-05 泽农医药公司 杂环衍生物及其用作硬脂酰CoA去饱和酶抑制剂的用途
AU2005286793A1 (en) 2004-09-20 2006-03-30 Xenon Pharmaceuticals Inc. Heterocyclic derivatives for the treatment of diseases mediated by stearoyl-CoA desaturase enzymes
BRPI0515482A (pt) 2004-09-20 2008-07-22 Xenon Pharmaceuticals Inc derivados heterocìclicos e seus usos como agentes terapêuticos
AR051090A1 (es) 2004-09-20 2006-12-20 Xenon Pharmaceuticals Inc Derivados heterociclicos y su uso como inhibidores de la estearoil-coa desaturasa
CN101083992A (zh) 2004-09-20 2007-12-05 泽农医药公司 抑制人硬脂酰CoA去饱和酶的哒嗪衍生物
EP1799668A1 (en) 2004-09-20 2007-06-27 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as mediators of stearoyl-coa desaturase
WO2006043121A1 (en) * 2004-10-20 2006-04-27 Ranbaxy Laboratories Limited Oxazolidinone derivatives as antimicrobials
EP2029138A1 (en) 2005-06-03 2009-03-04 Xenon Pharmaceuticals Inc. Aminothiazole derivatives as human stearoyl-coa desaturase inhibitors
EP1904489B1 (en) 2005-06-08 2011-01-26 Rib-X Pharmaceuticals, Inc. Process for the synthesis of triazoles
US7649007B2 (en) 2006-08-15 2010-01-19 Wyeth Llc Oxazolidine derivatives as PR modulators
US7652018B2 (en) 2006-08-15 2010-01-26 Wyeth Llc Imidazolidin-2-one derivatives useful as PR modulators
US7618989B2 (en) 2006-08-15 2009-11-17 Wyeth Tricyclic oxazolidone derivatives useful as PR modulators
US7538107B2 (en) 2006-08-15 2009-05-26 Wyeth Oxazinan-2-one derivatives useful as PR modulators
CN101798302B (zh) 2009-02-06 2014-11-05 上海盟科药业有限公司 抗生素类药物1-(邻-氟苯基)二氢吡啶酮的合成及生产的方法和工艺
WO2013182070A1 (zh) * 2012-06-08 2013-12-12 四川贝力克生物技术有限责任公司 一种用于预防或治疗分支杆菌疾病的药物

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR0146931B1 (ko) * 1992-04-30 1998-08-17 고바야시 유끼오 옥사졸리딘 유도체 및 그의 약학적으로 허용가능한 염
SK283420B6 (sk) * 1992-05-08 2003-07-01 Pharmacia & Upjohn Company Antimikrobiálne oxazolidinóny obsahujúce substituované diazínové skupiny
US5521202A (en) * 1993-04-07 1996-05-28 Taiho Pharmaceutical Co., Ltd. Thiazolidine derivatives and pharmaceutical compositions containing the same
DE4332384A1 (de) * 1993-09-23 1995-03-30 Merck Patent Gmbh Adhäsionsrezeptor-Antagonisten III
ES2123889T3 (es) * 1994-11-02 1999-01-16 Merck Patent Gmbh Antagonistas de receptores de adhesion.
CA2754102C (en) * 1995-08-14 2012-12-18 The Scripps Research Institute Monoclonal antibodies and compositions comprising such useful for inhibition of .alpha.v.beta.5 mediated angiogenesis
DK0856002T3 (da) * 1995-09-01 2002-02-11 Upjohn Co Phenyloxazolidinoner med en C-C-binding til 4-8 ledede heterocycliske ringe

Also Published As

Publication number Publication date
AU4156599A (en) 1999-12-30
NZ507973A (en) 2003-10-31
KR20010052590A (ko) 2001-06-25
WO1999064416A2 (en) 1999-12-16
HUP0103404A3 (en) 2002-08-28
DE69914478T2 (de) 2004-11-11
CN1304410A (zh) 2001-07-18
EP1082322B1 (en) 2004-01-28
EP1357122A3 (en) 2003-12-10
IL140085A0 (en) 2002-02-10
JP2002517497A (ja) 2002-06-18
ATE258552T1 (de) 2004-02-15
CA2332831A1 (en) 1999-12-16
NO20006149D0 (no) 2000-12-04
EP1357122A2 (en) 2003-10-29
GB9812019D0 (en) 1998-07-29
HUP0103404A2 (hu) 2002-05-29
AU753865B2 (en) 2002-10-31
ZA200006697B (en) 2002-02-18
NO20006149L (no) 2001-02-02
WO1999064416A3 (en) 2000-01-27
DE69914478D1 (de) 2004-03-04
EP1082322A2 (en) 2001-03-14

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6A, 7A E 8A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1911 DE 21/08/2007.