ATE2532T1 - Verfahren zur herstellung von omega-amino-1hydroxyalkyliden-1,1-bisphosphonsaeuren. - Google Patents

Verfahren zur herstellung von omega-amino-1hydroxyalkyliden-1,1-bisphosphonsaeuren.

Info

Publication number
ATE2532T1
ATE2532T1 AT81102991T AT81102991T ATE2532T1 AT E2532 T1 ATE2532 T1 AT E2532T1 AT 81102991 T AT81102991 T AT 81102991T AT 81102991 T AT81102991 T AT 81102991T AT E2532 T1 ATE2532 T1 AT E2532T1
Authority
AT
Austria
Prior art keywords
acid
omega
amino
mixture
preparation
Prior art date
Application number
AT81102991T
Other languages
German (de)
English (en)
Inventor
Helmut Blum
Karl-Heinz Dr. Worms
Original Assignee
Henkel Kommanditgesellschaft Auf Aktien
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Henkel Kommanditgesellschaft Auf Aktien filed Critical Henkel Kommanditgesellschaft Auf Aktien
Application granted granted Critical
Publication of ATE2532T1 publication Critical patent/ATE2532T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3839—Polyphosphonic acids
    • C07F9/3873—Polyphosphonic acids containing nitrogen substituent, e.g. N.....H or N-hydrocarbon group which can be substituted by halogen or nitro(so), N.....O, N.....S, N.....C(=X)- (X =O, S), N.....N, N...C(=X)...N (X =O, S)
    • C—CHEMISTRY; METALLURGY
    • C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02F1/00—Treatment of water, waste water, or sewage
    • C02F1/68—Treatment of water, waste water, or sewage by addition of specified substances, e.g. trace elements, for ameliorating potable water
    • C02F1/683—Treatment of water, waste water, or sewage by addition of specified substances, e.g. trace elements, for ameliorating potable water by addition of complex-forming compounds
    • C—CHEMISTRY; METALLURGY
    • C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02F5/00—Softening water; Preventing scale; Adding scale preventatives or scale removers to water, e.g. adding sequestering agents
    • C02F5/08—Treatment of water with complexing chemicals or other solubilising agents for softening, scale prevention or scale removal, e.g. adding sequestering agents
    • C02F5/10—Treatment of water with complexing chemicals or other solubilising agents for softening, scale prevention or scale removal, e.g. adding sequestering agents using organic substances
    • C02F5/14—Treatment of water with complexing chemicals or other solubilising agents for softening, scale prevention or scale removal, e.g. adding sequestering agents using organic substances containing phosphorus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Environmental & Geological Engineering (AREA)
  • Hydrology & Water Resources (AREA)
  • Engineering & Computer Science (AREA)
  • Water Supply & Treatment (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT81102991T 1980-04-28 1981-04-18 Verfahren zur herstellung von omega-amino-1hydroxyalkyliden-1,1-bisphosphonsaeuren. ATE2532T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19803016289 DE3016289A1 (de) 1980-04-28 1980-04-28 Verfahren zur herstellung von omega -amino-1-hydroxyalkyliden-1,1-bis-phosphonsaeuren
EP81102991A EP0039033B1 (de) 1980-04-28 1981-04-18 Verfahren zur Herstellung von omega-Amino-1-hydroxyalkyliden-1,1-bisphosphonsäuren

Publications (1)

Publication Number Publication Date
ATE2532T1 true ATE2532T1 (de) 1983-03-15

Family

ID=6101134

Family Applications (1)

Application Number Title Priority Date Filing Date
AT81102991T ATE2532T1 (de) 1980-04-28 1981-04-18 Verfahren zur herstellung von omega-amino-1hydroxyalkyliden-1,1-bisphosphonsaeuren.

Country Status (5)

Country Link
US (1) US4407761A (en:Method)
EP (1) EP0039033B1 (en:Method)
JP (1) JPS5731691A (en:Method)
AT (1) ATE2532T1 (en:Method)
DE (2) DE3016289A1 (en:Method)

Families Citing this family (86)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2489334A1 (fr) * 1980-09-04 1982-03-05 Vysoka Skola Chem Tech Acide 6-amino-1-hydroxyhexilidene-diphosphonique, ses sels, et procede pour l'obtention de ces produits
IT1194748B (it) * 1981-02-12 1988-09-28 Gentili Ist Spa Composizioni farmaceutiche per il trattamento di osteopatie
IT1201087B (it) * 1982-04-15 1989-01-27 Gentili Ist Spa Bifosfonati farmacologicamente attivi,procedimento per la loro preparazione e relative composizioni farmaceutiche
DE19675047I2 (de) * 1982-04-15 2003-06-12 Gentili Ist Spa Pharmazeutische Zusammensetzung mit einem Gehalt an 4-amino-1-hydroxybutan-1, 1-biphosphonsaeure
DE3225469A1 (de) * 1982-07-05 1984-01-05 Schering AG, 1000 Berlin und 4709 Bergkamen Diphosphonsaeure-derivate und diese enthaltende pharmazeutische praeparate
DE3334211A1 (de) * 1983-09-22 1985-04-04 Henkel KGaA, 4000 Düsseldorf Dihydroxyalkandiphosphonsaeuren
US4639338A (en) * 1984-08-06 1987-01-27 Ciba-Geigy Corporation Preparation of crystalline disodium 3-amino-1-hydroxypropane-1,1-diphosphonate pentahydrate
DE3434667A1 (de) * 1984-09-21 1986-04-03 Henkel KGaA, 4000 Düsseldorf 4-dimethylamino-1-hydroxybutan-1,1-diphosphonsaeure, deren wasserloesliche salze, verfahren zu ihrer herstellung sowie ihre verwendung
IT1196315B (it) * 1984-10-29 1988-11-16 Gentili Ist Spa Procedimento per la preparazione di acidi difosfonici
IL77243A (en) * 1984-12-21 1996-11-14 Procter & Gamble Pharmaceutical compositions containing geminal diphosphonic acid compounds and certain such novel compounds
DE3540150A1 (de) * 1985-11-13 1987-05-14 Boehringer Mannheim Gmbh Neue diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel
IL86951A (en) * 1987-07-06 1996-07-23 Procter & Gamble Pharma Methylene phosphonoalkylphosphinates and pharmaceutical preparations containing them
US4963681A (en) * 1987-07-06 1990-10-16 Norwich Eaton Pharmaceuticals, Inc. Process for synthesis of aminomethylene phosphonoalkylphosphinates
DE3805663A1 (de) * 1988-02-24 1989-09-07 Henkel Kgaa Oxaalkanpolyphosphonsaeuren, ihre verwendung als thresholder sowie diese verbindungen enthaltende, komplexierend wirkende zusammensetzungen
US4922007A (en) * 1989-06-09 1990-05-01 Merck & Co., Inc. Process for preparing 4-amino-1-hydroxybutylidene-1,1-bisphosphonic acid or salts thereof
US5019651A (en) * 1990-06-20 1991-05-28 Merck & Co., Inc. Process for preparing 4-amino-1-hydroxybutylidene-1,1-bisphosphonic acid (ABP) or salts thereof
GB2248061A (en) * 1990-09-18 1992-03-25 Merck & Co Inc Amino-hydroxy-alkylidene bis phosphonic acids
US5039819A (en) * 1990-09-18 1991-08-13 Merck & Co., Inc. Diphosphonate intermediate for preparing an antihypercalcemic agent
US5159108A (en) * 1990-09-18 1992-10-27 Merck & Co., Inc. Process for preparing an antihypercalcemic agent
IT1246992B (it) * 1991-01-08 1994-12-12 Gentili Ist Spa Procedimento per la preparazione di acidi difosfonici e loro sali
US5183815A (en) * 1991-01-22 1993-02-02 Merck & Co., Inc. Bone acting agents
KR950701929A (ko) * 1992-05-29 1995-05-17 제이코버스 코넬리스 레이서 비정상적인 칼슘 및 인산염 대사를 치료하기 위한 황-함유 포스포네이트 화합물(sulfur-containing phosphonate compounds for treating abnormal calcium and phosphate metabolism)
US5753634A (en) * 1992-05-29 1998-05-19 The Procter & Gamble Company Quaternary nitrogen containing phosphonate compounds, pharmaceutical compostions, and methods for treating abnormal calcium and phosphate metabolism
JPH07506569A (ja) * 1992-05-29 1995-07-20 プロクター、エンド、ギャンブル、ファーマスーティカルズ、インコーポレーテッド 異常カルシウム及びリン酸代謝と歯石及び歯垢を治療するための四級窒素含有ホスホネート化合物
US5391743A (en) * 1992-05-29 1995-02-21 Procter & Gamble Pharmaceuticals, Inc. Quaternary nitrogen-containing phosphonate compounds, pharmaceutical compositions, and methods of treating abnormal calcium and phosphate metabolism and methods of treating and preventing dental calculus and plaque
SG47603A1 (en) * 1992-05-29 1998-04-17 Procter & Gamble Pharma Thio-substitute nitrogen containing heterocyclic phosphonate compounds for treating abnormal calcium and phosphate metabolism
US5763611A (en) * 1992-05-29 1998-06-09 The Procter & Gamble Company Thio-substituted cyclic phosphonate compounds, pharmaceutical compositions, and methods for treating abnormal calcium and phosphate metabolism
US5358941A (en) * 1992-12-02 1994-10-25 Merck & Co., Inc. Dry mix formulation for bisphosphonic acids with lactose
US5510517A (en) * 1993-08-25 1996-04-23 Merck & Co., Inc. Process for producing N-amino-1-hydroxy-alkylidene-1,1-bisphosphonic acids
TW257765B (en:Method) * 1993-08-25 1995-09-21 Merck & Co Inc
US20010007863A1 (en) * 1998-06-18 2001-07-12 Merck & Co., Inc. Wet granulation formulation for bisphosphonic acids
KR100192215B1 (ko) * 1996-09-03 1999-06-15 강재헌 3-아미노-1-히드록시프로판-1,1-디포스폰산의 제조방법
CA2197267C (en) * 1997-02-11 2000-02-08 Yong Tao Process for the production of 4-amino-1-hydroxybutylidene-1,1-bisphosphonic acid or salts thereof
RO122854B1 (ro) * 1998-08-27 2010-03-30 Teva Pharmaceutical Industries Ltd. Alendronat de sodiu hidrat, procedeu de obţinere şi compoziţie farmaceutică
SK285163B6 (sk) * 1999-02-17 2006-07-07 Teva Pharmaceutical Industries Ltd. Spôsob prípravy kyseliny alendrónovej
US6315566B1 (en) 1999-05-18 2001-11-13 3M Innovative Properties Company Dental materials
US6143919A (en) * 1999-05-18 2000-11-07 3M Innovative Properties Company Polymerizable acidic compounds and methods of preparation
US6963008B2 (en) * 1999-07-19 2005-11-08 Teva Pharmaceutical Industries Ltd. Hydrate forms of alendronate sodium, processes for manufacture thereof, and pharmaceutical compositions thereof
ES2153794B1 (es) 1999-08-06 2001-10-16 Medichem Sa Procedimiento para la obtencion del acido 4-amino-1-hidroxibutiliden-1,1-bisfosfonico y de su sal monosodica trihidratada.
AR021347A1 (es) 1999-10-20 2002-07-17 Cipla Ltd Una composicion farmaceutica que contiene acido(s) bisfosfoncio o sal(es) del mismo y un proceso de preparacion de la misma
US6677320B2 (en) 2000-01-20 2004-01-13 Hoffmann-La Roches Inc. Parenteral bisphosphonate composition with improved local tolerance
US6410520B2 (en) 2000-02-01 2002-06-25 The Procter & Gamble Company Selective crystallization of 3-pyridyl-1-hydroxyethylidene-1, 1-bisphosphonic acid sodium as the hemipentahydrate or monohydrate
US6562974B2 (en) 2000-02-01 2003-05-13 The Procter & Gamble Company Process for making geminal bisphosphonates
US6476006B2 (en) 2000-06-23 2002-11-05 Teva Pharmaceutical Industries, Ltd. Composition and dosage form for delayed gastric release of alendronate and/or other bis-phosphonates
JP2004519463A (ja) * 2001-01-23 2004-07-02 ガドール エス アー 骨の代謝病の予防および／または治療のための組成物、その組成物の調製方法およびその使用
TR200101250A2 (tr) * 2001-05-10 2003-04-21 E�S Eczaciba�I �Zg�N K�Myasal �R�Nler Sanay� A.�. 4-amino-1-hidroksibutiliden-1,1-bifosfonik asit veya tuzlarının hazırlanmasına ilişkin proses
GB0115824D0 (en) * 2001-06-28 2001-08-22 Rhodia Cons Spec Ltd Improved solvent systems
PL371264A1 (en) * 2001-12-21 2005-06-13 The Procter & Gamble Company Method for the treatment of bone disorders
ITMI20020908A1 (it) * 2002-04-29 2003-10-29 Chemi Spa Processo di preparazione di sodio alendronato
KR20120065435A (ko) 2002-05-10 2012-06-20 에프. 호프만-라 로슈 아게 골다공증 치료 및 예방용 비스포스폰산
JP3857706B2 (ja) * 2002-05-17 2006-12-13 テバ ファーマシューティカル インダストリーズ リミティド ビスホスホン酸作製のための特定の希釈剤の使用
JP4485117B2 (ja) * 2002-06-27 2010-06-16 日東電工株式会社 保護剥離用フィルム
US20040138180A1 (en) * 2002-10-03 2004-07-15 Barr Laboratories, Inc. Bisphosphonate composition and process for the preparation thereof
AU2003250218B2 (en) * 2002-12-20 2006-10-26 F. Hoffmann-La Roche Ag High dose Ibandronate formulation
US20040206932A1 (en) 2002-12-30 2004-10-21 Abuelyaman Ahmed S. Compositions including polymerizable bisphosphonic acids and methods
HUP0300227A2 (hu) * 2003-01-28 2004-09-28 Richter Gedeon Vegyészeti Gyár Rt. Eljárás nagy tisztaságú 2-szubsztituált -1-(hidroxi-etilidén)-1,1-biszfoszfonsavak és sóik előállítására
US20040213917A1 (en) * 2003-04-23 2004-10-28 Courtney Douglas L. Spray booth and filter system
CN1325506C (zh) * 2003-05-15 2007-07-11 中国科学院上海药物研究所 骨重吸收抑制剂阿伦膦酸及生理可接受的盐和它的制备
US7452924B2 (en) * 2003-08-12 2008-11-18 3M Espe Ag Self-etching emulsion dental compositions and methods
US7411087B2 (en) * 2003-08-21 2008-08-12 Sun Pharmaceutical Industries Limited Process for preparation of bisphosphonic acid compounds
EP2206717B1 (en) * 2003-12-23 2013-03-27 Alchymars S.p.A. A process for the preparation of alkyl- and aryl-diphosphonic acids and salts thereof
WO2006014597A1 (en) 2004-07-08 2006-02-09 3M Innovative Properties Company Dental methods, compositions, and kits including acid-sensitive dyes
KR101260525B1 (ko) 2004-08-11 2013-05-06 쓰리엠 도이칠란드 게엠베하 다수의 산성 화합물을 포함하는 자체-접착성 조성물
US7361761B2 (en) * 2004-09-28 2008-04-22 Orchid Chemicals & Pharmaceuticals Ltd. Process for the preparation of bisphosphonic acid
PL199215B1 (pl) * 2004-12-28 2008-08-29 Politechnika Gdanska Sposób wytwarzania kwasu [1-hydroksy-2-(3-pirydylo)etylidenobisfosfonowego] oraz jego soli monosodowej dwu i pół wodnej
EP1891081B1 (en) * 2005-06-13 2014-08-20 Jubilant Organosys Limited Process for producing bisphosphonic acids and forms thereof
US8003820B2 (en) * 2005-10-20 2011-08-23 Dr. Reddy's Laboratories Limited Process for preparing bisphosphonic acids
PT1803727E (pt) * 2005-12-27 2009-06-15 Ipca Lab Ltd Processo melhorado para o fabrico de ácido 4-amino-hidroxibutilideno-1,1 bisfosfónico e seus sais
WO2007083240A2 (en) 2006-01-20 2007-07-26 Aurobindo Pharma Limited An improved process for the preparation of bisphosphonic acids
EP1984430A2 (de) 2006-02-03 2008-10-29 Universität Stuttgart - Institut für Chemische Verfahrenstechnik Phosphonsäure-haltige blends und phosphonsäure-haltige polymere
MX2008014248A (es) * 2006-05-11 2009-02-23 Ind Swift Lab Ltd Proceso para la preparacion de sales y acido risedronico puros.
CA2570949A1 (en) * 2006-12-12 2008-06-12 Apotex Pharmachem Inc. Ibandronate sodium propylene glycol solvate and processes for the preparation thereof
CN101557791B (zh) 2006-12-13 2013-05-22 3M创新有限公司 使用具有酸性组分和可光漂白染料的牙科用组合物的方法
WO2009050731A2 (en) * 2007-06-20 2009-04-23 Alkem Laboratories Ltd Novel process for preparing risedronic acid
US8026388B2 (en) * 2008-07-11 2011-09-27 Synthon Bv Process for making 1-hydroxyalkylidene-1,1-biphosphonic acids
US7964584B2 (en) * 2008-08-01 2011-06-21 Dong Wha Pharmaceutical Co., Ltd. Method of treating or preventing osteoporosis comprising administering to a patient in need thereof an effective amount of pharmaceutical composition comprising benzamidine derivatives or their salts, and alendronic acid or its salt
US20100130746A1 (en) * 2008-11-26 2010-05-27 Martin Kas Process for Making Zoledronic Acid
EA201270328A1 (ru) 2009-08-28 2012-09-28 Синтон Б. В. Способ получения 1-гидроксиалкилиден-1,1-дифосфоновых кислот
CA2775004A1 (en) 2009-10-02 2011-04-07 Straitmark Holding Ag Method for the manufacture of aminohydroxy diphosphonic acids
EP2609101B1 (en) 2010-07-14 2015-01-28 Pharmathen S.A. Process for the preparation of 3-(n-methyl-n-pentyl)amino-1-hydroxypropane-1,1-diphosphonic acid salt or derivatives thereof
FI20115315A0 (fi) * 2011-04-01 2011-04-01 Itae Suomen Yliopisto Menetelmä metallien keräämiseksi
EP2875036A1 (en) 2012-07-17 2015-05-27 Straitmark Holding AG Method for the synthesis of aminoalkylenephosphonic acid
RU2674022C9 (ru) 2012-07-17 2019-01-24 МОНСАНТО ТЕКНОЛОДЖИ ЭлЭлСи Способ синтеза альфа-аминоалкиленфосфоновой кислоты
IN2015DN01082A (en:Method) * 2012-07-17 2015-06-26 Straitmark Holding Ag
PL407922A1 (pl) 2014-04-16 2015-10-26 Wrocławskie Centrum Badań Eit + Spółka Z Ograniczoną Odpowiedzialnością Nowe bisfosfoniany i ich zastosowanie
CN106179235A (zh) * 2016-08-29 2016-12-07 江苏海普功能材料有限公司 一种除化学镍吸附剂及其制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2130794C3 (de) * 1971-06-22 1974-07-11 Joh. A. Benckiser Gmbh, 6700 Ludwigshafen Verfahren zur Herstellung von l-Hydroxy-S-amino-propan-ljl-diphosphonsäure
DE2534391C2 (de) * 1975-08-01 1983-01-13 Henkel KGaA, 4000 Düsseldorf 1-Hydroxy-3-aminoalkan-1,1-diphosphonsäuren
DE2658961C3 (de) 1976-12-24 1981-09-24 Joh. A. Benckiser Gmbh, 6700 Ludwigshafen Verfahren zur Herstellung von 1-Hydroxy-3-amino-propan-1,1-diphosphonsäuren
DE2702631A1 (de) 1977-01-22 1978-07-27 Henkel Kgaa Verfahren zur herstellung von 1-hydroxy-3-amino-propan-1,1-diphosphonsaeuren
DE2745083C2 (de) * 1977-10-07 1985-05-02 Henkel KGaA, 4000 Düsseldorf Hydroxydiphosphonsäuren und Verfahren zu deren Herstellung
DE2943498C2 (de) * 1979-10-27 1983-01-27 Henkel KGaA, 4000 Düsseldorf Verfahren zur Herstellung von 3-Amino-1-hydroxypropan-1,1-diphosphonsäure
US4304734A (en) * 1980-10-16 1981-12-08 Vysoka Skola Chemicko-Technologicka 6-Amino-1-hydroxyhexylidene diphosphonic acid, salts and a process for production thereof

Also Published As

Publication number Publication date
EP0039033B1 (de) 1983-02-16
DE3160078D1 (en) 1983-03-24
EP0039033A1 (de) 1981-11-04
JPH0120159B2 (en:Method) 1989-04-14
JPS5731691A (en) 1982-02-20
US4407761A (en) 1983-10-04
DE3016289A1 (de) 1981-10-29

Similar Documents

Publication Publication Date Title
ATE2532T1 (de) Verfahren zur herstellung von omega-amino-1hydroxyalkyliden-1,1-bisphosphonsaeuren.
ATE1242T1 (de) Verfahren zur herstellung von 3-amino-1-hydroxypropan-1,1-diphosphonsaeure.
DK0462663T3 (da) Forbedret fremgangsmåde til fremstilling af 4-amino-1-hydroxybutyliden-1,1-bisphosphonsyre (ABP) eller salte deraf
SE8504687D0 (sv) Forfarande for framstellning av difosfonsyror
JPS5377015A (en) Preparation of fluorine-containing phosphoric acid ester
DE69331314D1 (de) Verfahren zur Herstellung von N-Phosphonomethyliminodiessigsäure
KR840005158A (ko) N-포스포노 메틸글리신의 제조방법
ATE44382T1 (de) Verfahren zur herstellung von l-homoalanin-4yl(methyl)-phosphinsaeure sowie ihrer alkylester.
ATE67500T1 (de) Verfahren zur herstellung von aminomethylenphosphonalkylphosphinaten.
DE69202062D1 (de) Verfahren zur Herstellung von Diphosphonsäuren und Salzen davon.
ATE21107T1 (de) Verfahren zur herstellung von 3-amino-1hydroxypropan-1,1-diphosphonsaeure.
ATE12501T1 (de) Verfahren zur herstellung von methyldichlorphosphan.
ATE12775T1 (de) Verfahren zur herstellung von aminomethylphosphonsaeure.
ATE77T1 (de) N,n'-dialkyl-ureidomethan-diphosphonsaeure, deren herstellung und verwendung.
DE3767903D1 (de) Verfahren zur herstellung von alkali-phosphonoformiaten.
EP0155165A3 (en) Process for introducing phosphinoyl groups into amino groups
ATE55372T1 (de) Verfahren zur herstellung von 4-chlorbutanalen.
EP0241115A3 (en) Process for producing unsaturated phosphonic acid dichlorides
ATE13763T1 (de) Verfahren zur herstellung von n-(1-formylamido2,2,2-trichloraethyl)-morpholin.
ATE82256T1 (de) N-sulfomethylglycinate, verfahren zu ihrer herstellung und ihre verwendung bei der herstellung von glyphosat-herbiziden.
ATE16392T1 (de) Verfahren zur herstellung von dichlor-phenylphosphan.
IT1251707B (it) Procedimento per la produzione di acido n-fosfonometiliminodiacetico.

Legal Events

Date Code Title Description
EEIH Change in the person of patent owner
EELA Cancelled due to lapse of time