ATE250047T1 - Verfahren zur herstellung von aminoepoxiden aus aminoaldehyden und einem in situ erzeugten halogenomethylorganometallischen reagenz - Google Patents

Verfahren zur herstellung von aminoepoxiden aus aminoaldehyden und einem in situ erzeugten halogenomethylorganometallischen reagenz

Info

Publication number
ATE250047T1
ATE250047T1 AT97953210T AT97953210T ATE250047T1 AT E250047 T1 ATE250047 T1 AT E250047T1 AT 97953210 T AT97953210 T AT 97953210T AT 97953210 T AT97953210 T AT 97953210T AT E250047 T1 ATE250047 T1 AT E250047T1
Authority
AT
Austria
Prior art keywords
reagent
halogenomethylorganometallic
aminoepoxides
aminoaldehydes
producing
Prior art date
Application number
AT97953210T
Other languages
English (en)
Inventor
Chin Liu
John S Ng
James R Behling
Arthur L Campbell
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Searle & Co filed Critical Searle & Co
Application granted granted Critical
Publication of ATE250047T1 publication Critical patent/ATE250047T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/36—Compounds containing oxirane rings with hydrocarbon radicals, substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Epoxy Compounds (AREA)
  • Phenolic Resins Or Amino Resins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Resins (AREA)
AT97953210T 1996-12-31 1997-12-19 Verfahren zur herstellung von aminoepoxiden aus aminoaldehyden und einem in situ erzeugten halogenomethylorganometallischen reagenz ATE250047T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3380196P 1996-12-31 1996-12-31
PCT/US1997/022989 WO1998029401A1 (en) 1996-12-31 1997-12-19 Aminoepoxides from aminoaldehydes and in-situ formed halomethyl organometallic reagent

Publications (1)

Publication Number Publication Date
ATE250047T1 true ATE250047T1 (de) 2003-10-15

Family

ID=21872516

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97953210T ATE250047T1 (de) 1996-12-31 1997-12-19 Verfahren zur herstellung von aminoepoxiden aus aminoaldehyden und einem in situ erzeugten halogenomethylorganometallischen reagenz

Country Status (21)

Country Link
US (1) US6127556A (de)
EP (1) EP0970066B1 (de)
JP (1) JP3710488B2 (de)
KR (1) KR100523190B1 (de)
CN (1) CN1247535A (de)
AT (1) ATE250047T1 (de)
AU (1) AU733905B2 (de)
BR (1) BR9714129A (de)
CA (1) CA2276488C (de)
CY (1) CY2521B1 (de)
CZ (1) CZ297432B6 (de)
DE (1) DE69725014T2 (de)
ES (1) ES2207760T3 (de)
IL (1) IL130609A (de)
NO (1) NO320276B1 (de)
NZ (1) NZ336451A (de)
PL (1) PL334387A1 (de)
PT (1) PT970066E (de)
RO (1) RO120135B1 (de)
RU (1) RU2194045C2 (de)
WO (1) WO1998029401A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6123662A (en) 1998-07-13 2000-09-26 Acorn Cardiovascular, Inc. Cardiac disease treatment and device
US6085754A (en) 1998-07-13 2000-07-11 Acorn Cardiovascular, Inc. Cardiac disease treatment method
US6230714B1 (en) * 1998-11-18 2001-05-15 Acorn Cardiovascular, Inc. Cardiac constraint with prior venus occlusion methods
US6169922B1 (en) 1998-11-18 2001-01-02 Acorn Cardiovascular, Inc. Defibrillating cardiac jacket with interwoven electrode grids
US6155972A (en) 1999-02-02 2000-12-05 Acorn Cardiovascular, Inc. Cardiac constraint jacket construction
US6174279B1 (en) 1999-09-21 2001-01-16 Acorn Cardiovascular, Inc. Cardiac constraint with tension indicator
US6179791B1 (en) 1999-09-21 2001-01-30 Acorn Cardiovascular, Inc. Device for heart measurement
US6193648B1 (en) 1999-09-21 2001-02-27 Acorn Cardiovascular, Inc. Cardiac constraint with draw string tensioning
US6293906B1 (en) 2000-01-14 2001-09-25 Acorn Cardiovascular, Inc. Delivery of cardiac constraint jacket
PE20020276A1 (es) 2000-06-30 2002-04-06 Elan Pharm Inc COMPUESTOS DE AMINA SUSTITUIDA COMO INHIBIDORES DE ß-SECRETASA PARA EL TRATAMIENTO DE ALZHEIMER
EP1666452A2 (de) 2000-06-30 2006-06-07 Elan Pharmaceuticals, Inc. Verbindungen zur Behandlung der Alzheimerischen Krankheit
US6755779B2 (en) 2000-12-01 2004-06-29 Acorn Cardiovascular, Inc. Apparatus and method for delivery of cardiac constraint jacket
US6575921B2 (en) 2001-02-09 2003-06-10 Acorn Cardiovascular, Inc. Device for heart measurement
US6696594B2 (en) 2002-05-13 2004-02-24 Saudi Basic Industries Corporation Process for the conversion of aldehydes to esters
CA2673580C (en) 2006-12-29 2015-11-24 Abbott Gmbh & Co. Kg Carboxamide compounds and their use as calpain inhibitors
EP2288593A1 (de) * 2008-05-08 2011-03-02 Ranbaxy Laboratories Limited Verfahren zur herstellung von 3,4-epoxy-2-amino-1-substituierten butanderivaten und zwischenprodukte dafür
JP5744738B2 (ja) * 2008-09-24 2015-07-08 ザック システム ネビボロールの調製方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4268688A (en) * 1973-02-16 1981-05-19 Monsanto Company Asymmetric hydroformylation process
DE3711911A1 (de) * 1987-04-08 1988-10-20 Bayer Ag Optisch aktive (alpha)-aminoaldehyde, verfahren zu ihrer herstellung und ihre verwendung zur stereoselektiven herstellung optisch aktiver ss-aminoalkohole
CA2131182C (en) * 1992-05-20 2005-04-26 John S. Ng Method for making intermediates useful in synthesis of retroviral protease inhibitors
EP0855388B1 (de) * 1993-11-23 2002-03-06 G.D. Searle & Co. Verfahren zur Herstellung von Zwischenprodukten, die für die Herstellung von Retroviral-Protease hemmenden Verbindungen verwendbar sind
CA2137406C (en) * 1994-12-06 2005-09-13 Pierre Louis Beaulieu Process for key intermediates for hiv protease inhibitors

Also Published As

Publication number Publication date
JP2001507693A (ja) 2001-06-12
ES2207760T3 (es) 2004-06-01
CN1247535A (zh) 2000-03-15
US6127556A (en) 2000-10-03
NO320276B1 (no) 2005-11-21
EP0970066A1 (de) 2000-01-12
CA2276488C (en) 2006-07-18
WO1998029401A1 (en) 1998-07-09
KR20000069808A (ko) 2000-11-25
IL130609A0 (en) 2000-06-01
PT970066E (pt) 2004-02-27
DE69725014D1 (de) 2003-10-23
AU5700898A (en) 1998-07-31
CA2276488A1 (en) 1998-07-09
KR100523190B1 (ko) 2005-10-21
NZ336451A (en) 2000-09-29
NO993223D0 (no) 1999-06-29
CY2521B1 (en) 2006-02-08
CZ230599A3 (cs) 1999-11-17
NO993223L (no) 1999-08-24
DE69725014T2 (de) 2004-06-09
PL334387A1 (en) 2000-02-28
CZ297432B6 (cs) 2006-12-13
IL130609A (en) 2003-04-10
RO120135B1 (ro) 2005-09-30
AU733905B2 (en) 2001-05-31
JP3710488B2 (ja) 2005-10-26
EP0970066B1 (de) 2003-09-17
BR9714129A (pt) 2000-02-29
RU2194045C2 (ru) 2002-12-10

Similar Documents

Publication Publication Date Title
ATE250047T1 (de) Verfahren zur herstellung von aminoepoxiden aus aminoaldehyden und einem in situ erzeugten halogenomethylorganometallischen reagenz
DE3482094D1 (de) Bei hoher temperatur stabiler katalysator, verfahren zu dessen herstellung und verfahren zur durchfuehrung von chemischen reaktionen unter dessen verwendung.
NO308343B1 (no) Katalysatorblanding eller reaktantblanding, samt fremgangsmÕte for utførelse av kjemiske reaksjoner
ATE240923T1 (de) Herstellung von arylethern sowie damit verbundene reagentien und verfahren
DE3763072D1 (de) Katalytisches verfahren zur herstellung von oximen.
DE59810804D1 (de) Verfahren zur herstellung von gemischen monoolefinischer c 5-mononitrile durch katalytische hydrocyanierung in gebenwart eines katalysators, umfassend wenigstens einen metallocenphosphor (iii)-nickel(0)-komplex
ATE134203T1 (de) Dendritisches makromolecül und verfahren zu seiner herstellung
DE3765211D1 (de) Stabilisierter zirconocen/aluminoxan-katalysator und verfahren zur herstellung desselben.
DE69813170D1 (de) Silberkatalysator, Verfahren zu dessen Herstellung und Verfahren zur Herstellung von Ethylenoxid
DE3579850D1 (de) Verfahren zur herstellung von rohren aus mikriporoesem isoliermaterial und danach hergestellte rohre.
DE3773318D1 (de) Titanoxid-katalysator, verfahren zu dessen herstellung und dessen verwendung fuer die herstellung von linearen polyaethylenpolyaminen.
ATE147398T1 (de) 3,4-dimethyl-2,5-6-tris(p-sulfonatophenyl)-1- phosphanorbornadien, verfahren zu seiner herstellung und verfahren zur hydroformylierung von olefinisch ungesättigten verbindungen
ATE95809T1 (de) Verfahren zur herstellung von kohlenwasserstoffaminen.
DE60027341D1 (de) Verfahren zur Herstellung von Ammoniak und Ammoniak-Synthese-Katalysator
ATE212004T1 (de) Verfahren und vorrichtung zur herstellung von phosgen aus diphosgen und/oder triphosgen
ATE234827T1 (de) Verfahren zur herstellung von 3-aryl- benzofuranonen
DK1047669T3 (da) Perfluor-N-alkylsulfonsyrederivater
DE69017345D1 (de) Verfahren zur Herstellung von Cellobiose.
DE3762020D1 (de) Verfahren zur herstellung von hydrierungskatalysatoren aus hydrogelen und so hergestellte katalysatoren.
ATE71939T1 (de) Verfahren zur herstellung von 2,3,6trichlorpyridin und 2,3,5,6-tetrachlorpyridin in der gasphase.
DE69028833D1 (de) Verfahren zur herstellung ungesättigter ketone
DE69002017D1 (de) Katalytisches verfahren zur herstellung von oximen.
DE69924293D1 (de) Katalysatorsystem und verfahren zur dessen herstellung und dessen verwendung in einem polymerisationsverfahren
DE3865794D1 (de) Hydroraffinationskatalysator, ausgehend von hydrogelen, verfahren zur herstellung und verwendung.
DE69606305D1 (de) Katalyst, herstellungsverfahren und verwendung in einem verfahren zur herstellung von metyhlaminen

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 0970066

Country of ref document: EP

REN Ceased due to non-payment of the annual fee