IL130609A - Method for preparing aminoepoxides from aminoaldehydes - Google Patents

Method for preparing aminoepoxides from aminoaldehydes

Info

Publication number
IL130609A
IL130609A IL13060997A IL13060997A IL130609A IL 130609 A IL130609 A IL 130609A IL 13060997 A IL13060997 A IL 13060997A IL 13060997 A IL13060997 A IL 13060997A IL 130609 A IL130609 A IL 130609A
Authority
IL
Israel
Prior art keywords
organometallic reagent
mixing zone
preparing
protected aminoaldehyde
aminoepoxides
Prior art date
Application number
IL13060997A
Other languages
English (en)
Other versions
IL130609A0 (en
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Searle & Co filed Critical Searle & Co
Publication of IL130609A0 publication Critical patent/IL130609A0/xx
Publication of IL130609A publication Critical patent/IL130609A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/36—Compounds containing oxirane rings with hydrocarbon radicals, substituted by nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Epoxy Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Phenolic Resins Or Amino Resins (AREA)
  • Epoxy Resins (AREA)
IL13060997A 1996-12-31 1997-12-19 Method for preparing aminoepoxides from aminoaldehydes IL130609A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3380196P 1996-12-31 1996-12-31
PCT/US1997/022989 WO1998029401A1 (en) 1996-12-31 1997-12-19 Aminoepoxides from aminoaldehydes and in-situ formed halomethyl organometallic reagent

Publications (2)

Publication Number Publication Date
IL130609A0 IL130609A0 (en) 2000-06-01
IL130609A true IL130609A (en) 2003-04-10

Family

ID=21872516

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13060997A IL130609A (en) 1996-12-31 1997-12-19 Method for preparing aminoepoxides from aminoaldehydes

Country Status (21)

Country Link
US (1) US6127556A (de)
EP (1) EP0970066B1 (de)
JP (1) JP3710488B2 (de)
KR (1) KR100523190B1 (de)
CN (1) CN1247535A (de)
AT (1) ATE250047T1 (de)
AU (1) AU733905B2 (de)
BR (1) BR9714129A (de)
CA (1) CA2276488C (de)
CY (1) CY2521B1 (de)
CZ (1) CZ297432B6 (de)
DE (1) DE69725014T2 (de)
ES (1) ES2207760T3 (de)
IL (1) IL130609A (de)
NO (1) NO320276B1 (de)
NZ (1) NZ336451A (de)
PL (1) PL334387A1 (de)
PT (1) PT970066E (de)
RO (1) RO120135B1 (de)
RU (1) RU2194045C2 (de)
WO (1) WO1998029401A1 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6123662A (en) 1998-07-13 2000-09-26 Acorn Cardiovascular, Inc. Cardiac disease treatment and device
US6085754A (en) 1998-07-13 2000-07-11 Acorn Cardiovascular, Inc. Cardiac disease treatment method
US6230714B1 (en) * 1998-11-18 2001-05-15 Acorn Cardiovascular, Inc. Cardiac constraint with prior venus occlusion methods
US6169922B1 (en) 1998-11-18 2001-01-02 Acorn Cardiovascular, Inc. Defibrillating cardiac jacket with interwoven electrode grids
US6155972A (en) 1999-02-02 2000-12-05 Acorn Cardiovascular, Inc. Cardiac constraint jacket construction
US6179791B1 (en) 1999-09-21 2001-01-30 Acorn Cardiovascular, Inc. Device for heart measurement
US6193648B1 (en) 1999-09-21 2001-02-27 Acorn Cardiovascular, Inc. Cardiac constraint with draw string tensioning
US6174279B1 (en) 1999-09-21 2001-01-16 Acorn Cardiovascular, Inc. Cardiac constraint with tension indicator
US6293906B1 (en) 2000-01-14 2001-09-25 Acorn Cardiovascular, Inc. Delivery of cardiac constraint jacket
WO2001070672A2 (en) 2000-03-23 2001-09-27 Elan Pharmaceuticals, Inc. Compounds and methods to treat alzheimer's disease
US6846813B2 (en) 2000-06-30 2005-01-25 Pharmacia & Upjohn Company Compounds to treat alzheimer's disease
AU2001271686A1 (en) 2000-06-30 2002-01-14 Elan Pharmaceuticals, Inc. Compounds to treat alzheimer's disease
PE20020276A1 (es) 2000-06-30 2002-04-06 Elan Pharm Inc COMPUESTOS DE AMINA SUSTITUIDA COMO INHIBIDORES DE ß-SECRETASA PARA EL TRATAMIENTO DE ALZHEIMER
EP1666452A2 (de) 2000-06-30 2006-06-07 Elan Pharmaceuticals, Inc. Verbindungen zur Behandlung der Alzheimerischen Krankheit
US6755779B2 (en) 2000-12-01 2004-06-29 Acorn Cardiovascular, Inc. Apparatus and method for delivery of cardiac constraint jacket
US6575921B2 (en) 2001-02-09 2003-06-10 Acorn Cardiovascular, Inc. Device for heart measurement
CA2452039A1 (en) 2001-06-27 2003-01-09 Elan Pharmaceuticals, Inc. Beta-hydroxyamine derivatives useful in treatment of alzheimer's disease
US6696594B2 (en) 2002-05-13 2004-02-24 Saudi Basic Industries Corporation Process for the conversion of aldehydes to esters
JP5295976B2 (ja) 2006-12-29 2013-09-18 アボット ゲーエムベーハー ウント カンパニー カーゲー カルボキサミド化合物およびカルパイン阻害剤としてのこれらの使用
US20110178305A1 (en) * 2008-05-08 2011-07-21 Ranbaxy Laboratories Limited Process for the preparation of 3,4-epoxy-2-amino-1-substituted butane derivatives and intermediate compounds thereof
EP2328883B1 (de) * 2008-09-24 2014-08-06 Zach System Verfahren zur herstellung von nebivolol

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4268688A (en) * 1973-02-16 1981-05-19 Monsanto Company Asymmetric hydroformylation process
DE3711911A1 (de) * 1987-04-08 1988-10-20 Bayer Ag Optisch aktive (alpha)-aminoaldehyde, verfahren zu ihrer herstellung und ihre verwendung zur stereoselektiven herstellung optisch aktiver ss-aminoalkohole
AU4253193A (en) * 1992-05-20 1993-12-13 G.D. Searle & Co. Urea-containing hydroxyethylamine compounds as retroviral protease inhibitors
DE69424065T2 (de) * 1993-11-23 2000-09-28 G.D. Searle & Co., Chicago Verfahren zur herstellung von zwischenprodukten, die für die herstellung von retroviral-protease hemmenden verbindungen verwendbar sind
CA2137406C (en) * 1994-12-06 2005-09-13 Pierre Louis Beaulieu Process for key intermediates for hiv protease inhibitors

Also Published As

Publication number Publication date
DE69725014D1 (de) 2003-10-23
KR100523190B1 (ko) 2005-10-21
ATE250047T1 (de) 2003-10-15
PT970066E (pt) 2004-02-27
AU5700898A (en) 1998-07-31
US6127556A (en) 2000-10-03
DE69725014T2 (de) 2004-06-09
EP0970066B1 (de) 2003-09-17
AU733905B2 (en) 2001-05-31
IL130609A0 (en) 2000-06-01
CY2521B1 (en) 2006-02-08
BR9714129A (pt) 2000-02-29
NO320276B1 (no) 2005-11-21
PL334387A1 (en) 2000-02-28
CZ230599A3 (cs) 1999-11-17
CA2276488A1 (en) 1998-07-09
RO120135B1 (ro) 2005-09-30
NO993223D0 (no) 1999-06-29
EP0970066A1 (de) 2000-01-12
WO1998029401A1 (en) 1998-07-09
JP3710488B2 (ja) 2005-10-26
KR20000069808A (ko) 2000-11-25
NO993223L (no) 1999-08-24
ES2207760T3 (es) 2004-06-01
CN1247535A (zh) 2000-03-15
CA2276488C (en) 2006-07-18
RU2194045C2 (ru) 2002-12-10
CZ297432B6 (cs) 2006-12-13
NZ336451A (en) 2000-09-29
JP2001507693A (ja) 2001-06-12

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees