IL130609A - Method for preparing aminoepoxides from aminoaldehydes - Google Patents
Method for preparing aminoepoxides from aminoaldehydesInfo
- Publication number
- IL130609A IL130609A IL13060997A IL13060997A IL130609A IL 130609 A IL130609 A IL 130609A IL 13060997 A IL13060997 A IL 13060997A IL 13060997 A IL13060997 A IL 13060997A IL 130609 A IL130609 A IL 130609A
- Authority
- IL
- Israel
- Prior art keywords
- organometallic reagent
- mixing zone
- preparing
- protected aminoaldehyde
- aminoepoxides
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 239000003153 chemical reaction reagent Substances 0.000 abstract 5
- 239000007795 chemical reaction product Substances 0.000 abstract 1
- 125000002524 organometallic group Chemical group 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/36—Compounds containing oxirane rings with hydrocarbon radicals, substituted by nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Epoxy Compounds (AREA)
- Epoxy Resins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Phenolic Resins Or Amino Resins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3380196P | 1996-12-31 | 1996-12-31 | |
| PCT/US1997/022989 WO1998029401A1 (en) | 1996-12-31 | 1997-12-19 | Aminoepoxides from aminoaldehydes and in-situ formed halomethyl organometallic reagent |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL130609A0 IL130609A0 (en) | 2000-06-01 |
| IL130609A true IL130609A (en) | 2003-04-10 |
Family
ID=21872516
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL13060997A IL130609A (en) | 1996-12-31 | 1997-12-19 | Method for preparing aminoepoxides from aminoaldehydes |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US6127556A (de) |
| EP (1) | EP0970066B1 (de) |
| JP (1) | JP3710488B2 (de) |
| KR (1) | KR100523190B1 (de) |
| CN (1) | CN1247535A (de) |
| AT (1) | ATE250047T1 (de) |
| AU (1) | AU733905B2 (de) |
| BR (1) | BR9714129A (de) |
| CA (1) | CA2276488C (de) |
| CY (1) | CY2521B1 (de) |
| CZ (1) | CZ297432B6 (de) |
| DE (1) | DE69725014T2 (de) |
| ES (1) | ES2207760T3 (de) |
| IL (1) | IL130609A (de) |
| NO (1) | NO320276B1 (de) |
| NZ (1) | NZ336451A (de) |
| PL (1) | PL334387A1 (de) |
| PT (1) | PT970066E (de) |
| RO (1) | RO120135B1 (de) |
| RU (1) | RU2194045C2 (de) |
| WO (1) | WO1998029401A1 (de) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6123662A (en) | 1998-07-13 | 2000-09-26 | Acorn Cardiovascular, Inc. | Cardiac disease treatment and device |
| US6085754A (en) | 1998-07-13 | 2000-07-11 | Acorn Cardiovascular, Inc. | Cardiac disease treatment method |
| US6230714B1 (en) * | 1998-11-18 | 2001-05-15 | Acorn Cardiovascular, Inc. | Cardiac constraint with prior venus occlusion methods |
| US6169922B1 (en) | 1998-11-18 | 2001-01-02 | Acorn Cardiovascular, Inc. | Defibrillating cardiac jacket with interwoven electrode grids |
| US6155972A (en) | 1999-02-02 | 2000-12-05 | Acorn Cardiovascular, Inc. | Cardiac constraint jacket construction |
| US6179791B1 (en) | 1999-09-21 | 2001-01-30 | Acorn Cardiovascular, Inc. | Device for heart measurement |
| US6193648B1 (en) | 1999-09-21 | 2001-02-27 | Acorn Cardiovascular, Inc. | Cardiac constraint with draw string tensioning |
| US6174279B1 (en) | 1999-09-21 | 2001-01-16 | Acorn Cardiovascular, Inc. | Cardiac constraint with tension indicator |
| US6293906B1 (en) | 2000-01-14 | 2001-09-25 | Acorn Cardiovascular, Inc. | Delivery of cardiac constraint jacket |
| JP2003528071A (ja) | 2000-03-23 | 2003-09-24 | エラン ファーマスーティカルズ インコーポレイテッド | アルツハイマー病治療用組成物および方法 |
| PE20020276A1 (es) | 2000-06-30 | 2002-04-06 | Elan Pharm Inc | COMPUESTOS DE AMINA SUSTITUIDA COMO INHIBIDORES DE ß-SECRETASA PARA EL TRATAMIENTO DE ALZHEIMER |
| JP2004502665A (ja) | 2000-06-30 | 2004-01-29 | イーラン ファーマスーティカルズ、インコーポレイテッド | アルツハイマー病を治療する化合物 |
| US6846813B2 (en) | 2000-06-30 | 2005-01-25 | Pharmacia & Upjohn Company | Compounds to treat alzheimer's disease |
| EP1666452A2 (de) | 2000-06-30 | 2006-06-07 | Elan Pharmaceuticals, Inc. | Verbindungen zur Behandlung der Alzheimerischen Krankheit |
| US6755779B2 (en) | 2000-12-01 | 2004-06-29 | Acorn Cardiovascular, Inc. | Apparatus and method for delivery of cardiac constraint jacket |
| US6575921B2 (en) | 2001-02-09 | 2003-06-10 | Acorn Cardiovascular, Inc. | Device for heart measurement |
| WO2003002122A1 (en) | 2001-06-27 | 2003-01-09 | Elan Pharmaceuticals, Inc. | Beta-hydroxyamine derivatives useful in treatment of alzheimer's disease |
| US6696594B2 (en) | 2002-05-13 | 2004-02-24 | Saudi Basic Industries Corporation | Process for the conversion of aldehydes to esters |
| PT2439205E (pt) | 2006-12-29 | 2015-07-16 | Abbvie Deutschland | Compostos de carboxamida e seus usos como inibidores de calpaína |
| WO2009136365A1 (en) * | 2008-05-08 | 2009-11-12 | Ranbaxy Laboratories Limited | Process for the preparation of 3,4-epoxy-2-amino-1-substituted butane derivatives and intermediate compounds thereof |
| BRPI0919257B8 (pt) * | 2008-09-24 | 2021-05-25 | Zach System | processo de preparação de nebivolol |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4268688A (en) * | 1973-02-16 | 1981-05-19 | Monsanto Company | Asymmetric hydroformylation process |
| DE3711911A1 (de) * | 1987-04-08 | 1988-10-20 | Bayer Ag | Optisch aktive (alpha)-aminoaldehyde, verfahren zu ihrer herstellung und ihre verwendung zur stereoselektiven herstellung optisch aktiver ss-aminoalkohole |
| AU4253193A (en) * | 1992-05-20 | 1993-12-13 | G.D. Searle & Co. | Urea-containing hydroxyethylamine compounds as retroviral protease inhibitors |
| WO1995014653A1 (en) * | 1993-11-23 | 1995-06-01 | G.D. Searle & Co. | Method for making intermediates useful in synthesis of retroviral protease inhibitors |
| CA2137406C (en) * | 1994-12-06 | 2005-09-13 | Pierre Louis Beaulieu | Process for key intermediates for hiv protease inhibitors |
-
1997
- 1997-12-16 US US08/991,598 patent/US6127556A/en not_active Expired - Fee Related
- 1997-12-19 JP JP53006298A patent/JP3710488B2/ja not_active Expired - Fee Related
- 1997-12-19 PL PL97334387A patent/PL334387A1/xx not_active Application Discontinuation
- 1997-12-19 BR BR9714129-1A patent/BR9714129A/pt not_active Application Discontinuation
- 1997-12-19 AU AU57008/98A patent/AU733905B2/en not_active Ceased
- 1997-12-19 AT AT97953210T patent/ATE250047T1/de not_active IP Right Cessation
- 1997-12-19 WO PCT/US1997/022989 patent/WO1998029401A1/en not_active Ceased
- 1997-12-19 KR KR10-1999-7005958A patent/KR100523190B1/ko not_active Expired - Fee Related
- 1997-12-19 RU RU99116620/04A patent/RU2194045C2/ru not_active IP Right Cessation
- 1997-12-19 DE DE69725014T patent/DE69725014T2/de not_active Expired - Fee Related
- 1997-12-19 RO RO99-00756A patent/RO120135B1/ro unknown
- 1997-12-19 CA CA002276488A patent/CA2276488C/en not_active Expired - Fee Related
- 1997-12-19 ES ES97953210T patent/ES2207760T3/es not_active Expired - Lifetime
- 1997-12-19 IL IL13060997A patent/IL130609A/xx not_active IP Right Cessation
- 1997-12-19 NZ NZ336451A patent/NZ336451A/xx unknown
- 1997-12-19 CZ CZ0230599A patent/CZ297432B6/cs not_active IP Right Cessation
- 1997-12-19 PT PT97953210T patent/PT970066E/pt unknown
- 1997-12-19 CN CN97181934A patent/CN1247535A/zh active Pending
- 1997-12-19 EP EP97953210A patent/EP0970066B1/de not_active Expired - Lifetime
-
1999
- 1999-06-29 NO NO19993223A patent/NO320276B1/no unknown
-
2005
- 2005-03-16 CY CY0500018A patent/CY2521B1/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0970066B1 (de) | 2003-09-17 |
| CA2276488C (en) | 2006-07-18 |
| KR100523190B1 (ko) | 2005-10-21 |
| US6127556A (en) | 2000-10-03 |
| EP0970066A1 (de) | 2000-01-12 |
| PL334387A1 (en) | 2000-02-28 |
| DE69725014T2 (de) | 2004-06-09 |
| CA2276488A1 (en) | 1998-07-09 |
| JP3710488B2 (ja) | 2005-10-26 |
| AU5700898A (en) | 1998-07-31 |
| AU733905B2 (en) | 2001-05-31 |
| KR20000069808A (ko) | 2000-11-25 |
| CY2521B1 (en) | 2006-02-08 |
| ATE250047T1 (de) | 2003-10-15 |
| WO1998029401A1 (en) | 1998-07-09 |
| ES2207760T3 (es) | 2004-06-01 |
| DE69725014D1 (de) | 2003-10-23 |
| CZ297432B6 (cs) | 2006-12-13 |
| RO120135B1 (ro) | 2005-09-30 |
| NO993223L (no) | 1999-08-24 |
| IL130609A0 (en) | 2000-06-01 |
| PT970066E (pt) | 2004-02-27 |
| NZ336451A (en) | 2000-09-29 |
| RU2194045C2 (ru) | 2002-12-10 |
| NO993223D0 (no) | 1999-06-29 |
| NO320276B1 (no) | 2005-11-21 |
| CN1247535A (zh) | 2000-03-15 |
| BR9714129A (pt) | 2000-02-29 |
| CZ230599A3 (cs) | 1999-11-17 |
| JP2001507693A (ja) | 2001-06-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| MM9K | Patent not in force due to non-payment of renewal fees |