ATE247478T1 - Bioartifizielle vorrichtungen und hierfür verwendete zellhaltige matrix - Google Patents
Bioartifizielle vorrichtungen und hierfür verwendete zellhaltige matrixInfo
- Publication number
- ATE247478T1 ATE247478T1 AT96941993T AT96941993T ATE247478T1 AT E247478 T1 ATE247478 T1 AT E247478T1 AT 96941993 T AT96941993 T AT 96941993T AT 96941993 T AT96941993 T AT 96941993T AT E247478 T1 ATE247478 T1 AT E247478T1
- Authority
- AT
- Austria
- Prior art keywords
- cell
- used therefor
- matrix used
- containing matrix
- bioartificial devices
- Prior art date
Links
- 239000011159 matrix material Substances 0.000 title abstract 4
- 239000000017 hydrogel Substances 0.000 abstract 2
- 102000008186 Collagen Human genes 0.000 abstract 1
- 108010035532 Collagen Proteins 0.000 abstract 1
- 229920002307 Dextran Polymers 0.000 abstract 1
- 108010010803 Gelatin Proteins 0.000 abstract 1
- 125000002059 L-arginyl group Chemical class O=C([*])[C@](N([H])[H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H] 0.000 abstract 1
- 229940123134 Nitric oxide inhibitor Drugs 0.000 abstract 1
- 208000036142 Viral infection Diseases 0.000 abstract 1
- 230000001413 cellular effect Effects 0.000 abstract 1
- 229920001436 collagen Polymers 0.000 abstract 1
- 239000008273 gelatin Substances 0.000 abstract 1
- 229920000159 gelatin Polymers 0.000 abstract 1
- 235000019322 gelatine Nutrition 0.000 abstract 1
- 235000011852 gelatine desserts Nutrition 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
- 230000009385 viral infection Effects 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/02—Preservation of living parts
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/02—Preservation of living parts
- A01N1/0205—Chemical aspects
- A01N1/0231—Chemically defined matrices, e.g. alginate gels, for immobilising, holding or storing cells, tissue or organs for preservation purposes; Chemically altering or fixing cells, tissue or organs, e.g. by cross-linking, for preservation purposes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/022—Artificial gland structures using bioreactors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
- A61L27/222—Gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
- A61L27/24—Collagen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/26—Mixtures of macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0012—Cell encapsulation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0676—Pancreatic cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0676—Pancreatic cells
- C12N5/0677—Three-dimensional culture, tissue culture or organ culture; Encapsulated cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
- A61F2310/00005—The prosthesis being constructed from a particular material
- A61F2310/00365—Proteins; Polypeptides; Degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/126—Immunoprotecting barriers, e.g. jackets, diffusion chambers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/05—Inorganic components
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/32—Amino acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2509/00—Methods for the dissociation of cells, e.g. specific use of enzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/30—Synthetic polymers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/50—Proteins
- C12N2533/54—Collagen; Gelatin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/70—Polysaccharides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Transplantation (AREA)
- Genetics & Genomics (AREA)
- Dermatology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Epidemiology (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Environmental Sciences (AREA)
- Dentistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Biophysics (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Neurosurgery (AREA)
- Dispersion Chemistry (AREA)
- Botany (AREA)
- Obesity (AREA)
- Cardiology (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/568,694 US5830492A (en) | 1992-02-24 | 1995-12-07 | Bioartificial devices and cellular matrices therefor |
PCT/US1996/018209 WO1997020569A2 (en) | 1995-12-07 | 1996-11-14 | Bioartificial devices and cellular matrices therefor |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE247478T1 true ATE247478T1 (de) | 2003-09-15 |
Family
ID=24272337
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT96941993T ATE247478T1 (de) | 1995-12-07 | 1996-11-14 | Bioartifizielle vorrichtungen und hierfür verwendete zellhaltige matrix |
AT03075752T ATE321126T1 (de) | 1995-12-07 | 1996-11-14 | Hydrogelmatrix für zellgewebelagerung |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT03075752T ATE321126T1 (de) | 1995-12-07 | 1996-11-14 | Hydrogelmatrix für zellgewebelagerung |
Country Status (9)
Country | Link |
---|---|
US (1) | US5830492A (de) |
EP (2) | EP1321516B1 (de) |
JP (1) | JP3606585B2 (de) |
AT (2) | ATE247478T1 (de) |
AU (1) | AU714465B2 (de) |
CA (1) | CA2239498C (de) |
DE (2) | DE69635940T2 (de) |
WO (1) | WO1997020569A2 (de) |
ZA (1) | ZA9610297B (de) |
Families Citing this family (40)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6352707B1 (en) * | 1992-02-24 | 2002-03-05 | Anton-Lewis Usala | Transplant encapsulation in a hydrogel matrix to obscure immune recognition |
US5908633A (en) * | 1992-02-24 | 1999-06-01 | Usala; Anton-Lewis | Bioartificial hormone releasing device |
US6231881B1 (en) | 1992-02-24 | 2001-05-15 | Anton-Lewis Usala | Medium and matrix for long-term proliferation of cells |
US6703017B1 (en) | 1994-04-28 | 2004-03-09 | Ixion Biotechnology, Inc. | Reversal of insulin-dependent diabetes by islet-producing stem cells, islet progenitor cells and islet-like structures |
AU3623199A (en) * | 1998-05-15 | 1999-12-06 | Modex Therapeutiques, S.A. | Flat sheet cell encapsulation device |
AU757968B2 (en) * | 1998-07-10 | 2003-03-13 | Encelle, Inc. | Methods for increasing vascularization and promoting wound healing |
FR2801313A1 (fr) | 1999-05-19 | 2001-05-25 | Coletica | Produit collagenique contenant du collagene d'origine marine a faible odeur et de preference a proprietes mecaniques ameliorees, ainsi que son utilisation sous forme de compositions ou de produits cosmetiques ou pharmaceutiques |
EP1224259A4 (de) * | 1999-09-27 | 2005-04-27 | Univ Florida | Rückbildung von insulinabhängigem diabetes durch inselbildende stammzellen, inselvorläuferzellen und inselähnliche strukturen |
US20030167054A1 (en) * | 2000-05-05 | 2003-09-04 | Lawrence Rosenberg | Device for cell implantation |
US6790454B1 (en) | 2000-05-26 | 2004-09-14 | Coletica | Processes for the preparation of novel collagen-based supports for tissue engineering, and biomaterials obtained |
WO2001092322A1 (fr) * | 2000-05-26 | 2001-12-06 | Coletica | Utilisation de collagene d'origine aquatique pour la realisation de supports destines a l'ingenierie tissulaire, et supports et biomateriaux obtenus |
FR2809314B1 (fr) * | 2000-05-26 | 2005-11-18 | Coletica | Utilisation de collagene d'origine aquatique pour la realisation de supports destines a l'ingenierie tissulaire, et supports et biomateriaux obtenus |
US6974679B2 (en) | 2000-05-26 | 2005-12-13 | Coletica | Support with collagen base for tissue engineering and manufacture of biomaterials |
FR2809412A1 (fr) * | 2000-05-26 | 2001-11-30 | Coletica | Utilisation de collagene d'origine aquatique pour la realisation de supports destines a l'ingenierie tissulaire, et supports et biomateriaux obtenus |
AU2001263495B2 (en) * | 2000-05-31 | 2005-06-02 | Encelle, Inc. | Method of treating chronic ulcers |
EP2316394B1 (de) | 2001-06-12 | 2016-11-23 | The Johns Hopkins University | Reservoirvorrichtung für die intraokulare Arzneimittelabgabe |
WO2003002021A2 (en) | 2001-06-29 | 2003-01-09 | The Regents Of The University Of California | Biodegradable/bioactive nucleus pulposus implant and method for treating degenerated intervertebral discs |
US20080086792A1 (en) | 2006-10-13 | 2008-04-17 | Thomas Charles Kuracina | Method and apparatus for diverting sweat, liquid, moisture or the like from an eye |
CA2476656C (en) | 2002-02-21 | 2008-11-25 | Encelle, Inc. | Immobilized bioactive hydrogel matrices as surface coatings |
US7947759B2 (en) * | 2005-08-08 | 2011-05-24 | Angstrom Medica | Cement products and methods of making and using the same |
US20070098695A1 (en) * | 2005-10-31 | 2007-05-03 | Deolden James | Methods of islet separation during isolation |
JP4853637B2 (ja) | 2006-08-08 | 2012-01-11 | Kisco株式会社 | 細胞培養用基材およびその製造方法 |
US8815973B2 (en) * | 2007-08-28 | 2014-08-26 | Pioneer Surgical Technology, Inc. | Cement products and methods of making and using the same |
JP5237714B2 (ja) * | 2008-07-29 | 2013-07-17 | BioROIS株式会社 | 細胞輸送用担体及びそれを使用した細胞の輸送方法 |
US8623395B2 (en) | 2010-01-29 | 2014-01-07 | Forsight Vision4, Inc. | Implantable therapeutic device |
SG173167A1 (en) | 2009-01-29 | 2011-08-29 | Forsight Labs Llc | Posterior segment drug delivery |
CN105435338B (zh) | 2010-08-05 | 2019-03-26 | 弗赛特影像4股份有限公司 | 用于药物输送的注入器装置和方法 |
PT2600812T (pt) | 2010-08-05 | 2021-11-09 | Forsight Vision4 Inc | Aparelho para tratar um olho |
JP5592842B2 (ja) | 2011-06-24 | 2014-09-17 | Kisco株式会社 | 細胞培養用基膜、細胞培養用基材、及び細胞培養用基材の製造方法 |
WO2013040247A2 (en) | 2011-09-16 | 2013-03-21 | Forsight Vision4, Inc. | Fluid exchange apparatus and methods |
EP2574349A1 (de) * | 2011-09-29 | 2013-04-03 | Biorigen S.r.l | Therapeutische Verwendung von Gelatin-Hydrogelen mit Gel-Sol-Übergang bei Körpertemperatur |
WO2013045689A1 (en) | 2011-09-29 | 2013-04-04 | BIORIGEN Srl | Therapeutic use of gelatin hydrogels with a gel-sol transition at body temperature |
CN104080468A (zh) | 2011-11-02 | 2014-10-01 | 哈尔西恩股份有限公司 | 用于创伤治疗的方法和组合物 |
MX352601B (es) | 2011-12-23 | 2017-11-30 | Pioneer Surgical Tech | Matriz continua con particulas osteoconductoras dispersadas en ella, método para formarla y método para regenerar hueso con ella. |
EP2978393B1 (de) | 2013-03-28 | 2023-12-27 | ForSight Vision4, Inc. | Augenimplantat zur abgabe von therapeutischen substanzen |
CA3005238A1 (en) | 2015-11-20 | 2017-05-26 | Forsight Vision4, Inc. | Porous structures for extended release drug delivery devices |
WO2018165327A1 (en) | 2017-03-08 | 2018-09-13 | Alafair Biosciences, Inc. | Hydrogel medium for the storage and preservation of tissue |
JP7210095B2 (ja) * | 2019-06-28 | 2023-01-23 | 持田製薬株式会社 | 化学架橋アルギン酸を用いた移植用デバイス |
WO2022137345A1 (ja) * | 2020-12-22 | 2022-06-30 | 持田製薬株式会社 | 化学架橋アルギン酸を用いた移植用デバイス |
JP7451818B1 (ja) | 2023-11-10 | 2024-03-18 | 洋之 高尾 | Diffusion Chamber型人工膵島器 |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5132223A (en) * | 1983-11-10 | 1992-07-21 | Thomas Jefferson University | Process and medium for cloning and long-term serial cultivation of adult human endothelial cells |
CA1204399A (en) * | 1983-11-10 | 1986-05-13 | Elliot M. Levine | Process and medium for cloning and long-term serial cultivation of human endothelial cells |
US4868121A (en) * | 1985-02-07 | 1989-09-19 | Mcdonnell Douglas Corporation | Islet isolation process |
US4769404A (en) * | 1985-02-28 | 1988-09-06 | Technicon Instruments Corporation | Lyophilization of reagent-coated particles |
GB8604497D0 (en) * | 1986-02-24 | 1986-04-03 | Connaught Lab | Separation of islets of langerhans |
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SU1724687A1 (ru) * | 1990-05-05 | 1992-04-07 | Институт полиомиелита и вирусных энцефалитов АМН СССР | Способ получени желатиновых микроносителей дл культивировани клеток животных |
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DE69221484T2 (de) * | 1991-04-25 | 1998-02-19 | Univ Brown Res Found | Implantierbare, biokompatible immunisolator-trägersubstanz zum abgeben ausgesuchter, therapeutischer produkte |
JP3291297B2 (ja) * | 1992-02-24 | 2002-06-10 | エンセル,インコーポレイテッド | 生物人工内分泌装置 |
US5422261A (en) * | 1993-04-16 | 1995-06-06 | Baxter International Inc. | Composition containing collagenase and chymopapain for hydrolyzing connective tissue to isolate cells |
EP1418228B1 (de) * | 1994-01-13 | 2006-03-15 | The Rogosin Institute | Makroeingekapselte sekretorische Zellen |
-
1995
- 1995-12-07 US US08/568,694 patent/US5830492A/en not_active Expired - Lifetime
-
1996
- 1996-11-14 JP JP52127597A patent/JP3606585B2/ja not_active Expired - Lifetime
- 1996-11-14 EP EP03075752A patent/EP1321516B1/de not_active Expired - Lifetime
- 1996-11-14 EP EP96941993A patent/EP0865288B1/de not_active Expired - Lifetime
- 1996-11-14 AU AU11192/97A patent/AU714465B2/en not_active Expired
- 1996-11-14 DE DE69635940T patent/DE69635940T2/de not_active Expired - Lifetime
- 1996-11-14 AT AT96941993T patent/ATE247478T1/de not_active IP Right Cessation
- 1996-11-14 AT AT03075752T patent/ATE321126T1/de not_active IP Right Cessation
- 1996-11-14 CA CA002239498A patent/CA2239498C/en not_active Expired - Lifetime
- 1996-11-14 DE DE69629583T patent/DE69629583T2/de not_active Expired - Lifetime
- 1996-11-14 WO PCT/US1996/018209 patent/WO1997020569A2/en active IP Right Grant
- 1996-12-06 ZA ZA9610297A patent/ZA9610297B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
CA2239498A1 (en) | 1997-06-12 |
DE69635940D1 (de) | 2006-05-11 |
EP1321516A3 (de) | 2003-07-02 |
EP0865288B1 (de) | 2003-08-20 |
AU714465B2 (en) | 2000-01-06 |
AU1119297A (en) | 1997-06-27 |
US5830492A (en) | 1998-11-03 |
WO1997020569A3 (en) | 1997-09-18 |
JP2000507202A (ja) | 2000-06-13 |
EP0865288A2 (de) | 1998-09-23 |
EP1321516A2 (de) | 2003-06-25 |
WO1997020569A2 (en) | 1997-06-12 |
ZA9610297B (en) | 1997-06-18 |
DE69629583D1 (de) | 2003-09-25 |
EP1321516B1 (de) | 2006-03-22 |
JP3606585B2 (ja) | 2005-01-05 |
ATE321126T1 (de) | 2006-04-15 |
DE69635940T2 (de) | 2006-10-26 |
CA2239498C (en) | 2003-09-09 |
DE69629583T2 (de) | 2004-08-19 |
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